XAMDEX 100MCG INJECTION
MRP ₹847
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About XAMDEX 100MCG INJECTION
XAMDEX 100MCG INJECTION belongs to the group of sedatives used to sedate patients in acute settings such as the ICU, during surgical procedures and in those who require a mechanical ventilator. Sedation is defined as a state of relaxation, drowsiness or sleep.
XAMDEX 100MCG INJECTION contains Dexmedetomidine which works by inhibiting the release of an active neurotransmitter (nerve substance) called norepinephrine and subsequently blocks pain signals. Hence XAMDEX 100MCG INJECTION brings on a sense of relaxation and numbness through massive pain relief.
XAMDEX 100MCG INJECTION will be administered by a healthcare professional. Do not self-administer. XAMDEX 100MCG INJECTION may cause certain common side effects such as a slow heart rate, a change in blood pressure and an alteration in breathing pattern. You are advised to talk to your doctor if these side effects persist.
It is advisable to inform the doctor if you are allergic to any of the components of XAMDEX 100MCG INJECTION. Consult your doctor if you are pregnant, planning to get pregnant or if you are breastfeeding, as XAMDEX 100MCG INJECTION should be used with caution in these states. Avoid driving or operating machinery as XAMDEX 100MCG INJECTION causes sedation. Consult your doctor before consuming alcohol with XAMDEX 100MCG INJECTION.
Uses of XAMDEX 100MCG INJECTION
XAMDEX 100MCG INJECTION is used for Sedation. The detailed uses of XAMDEX 100MCG INJECTION are as follows:
- Sedation in intensive care units (ICU): XAMDEX 100MCG INJECTION is used for intubated and mechanically ventilated patients.
- Procedural sedation: XAMDEX 100MCG INJECTION is used for non-intubated patients during surgeries or diagnostic procedures.
- Postoperative pain management: XAMDEX 100MCG INJECTION is used to treat pain especially in high-risk patients.
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Directions for Use
- Your doctor will decide the dosage and timing of XAMDEX 100MCG INJECTION, depending on the desired level of sedation and your response to treatment.
- XAMDEX 100MCG INJECTION will be administered by a healthcare professional in a hospital setting.
- Do not self-administer this medication.
Key Benefits
XAMDEX 100MCG INJECTION is a sedative that is used for the purpose of sedation in acute settings such as the intensive care unit (ICU). XAMDEX 100MCG INJECTION finds application in aiding anaesthesia before surgical procedures and is also used to relax patients on mechanical ventilation. XAMDEX 100MCG INJECTION contains Dexmedetomidine. XAMDEX 100MCG INJECTION blocks pain signals, so the brain doesn't perceive pain or sensation and hence, brings on a sense of numbness and anaesthesia.
How XAMDEX 100MCG INJECTION Works
Storage
- Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
- Divide your daily food intake into smaller, more frequent meals to reduce nausea.
- Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
- Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
- Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
- Use ginger (tea, ale, or candies) to help relieve nausea.
- Get adequate rest and also avoid strenuous activities that can worsen nausea.
- Talk to your doctor about taking anti-nausea medication if your nausea is severe.
- Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
- If you experience low blood pressure symptoms like dizziness, lightheadedness, or fainting while taking medication, seek immediate medical attention.
- Make lifestyle modifications and adjust your medication regimen under medical guidance to manage low blood pressure.
- As your doctor advises, regularly check your blood pressure at home. Record your readings to detect any changes and share them with your doctor.
- Fluid intake plays a vital role in managing blood pressure by maintaining blood volume, regulating blood pressure, and supporting blood vessel function. Drinking enough fluids helps prevent dehydration, maintain electrolyte balance, and regulate fluid balance.
- Take regular breaks to sit or lie down if you need to stand for long periods.
- When lying down, elevate your head with extra pillows to help improve blood flow.
- Avoid heavy exercise or strenuous activities that can worsen low blood pressure.
- Wear compression socks as your doctor advises to enhance blood flow, reduce oedema, and control blood pressure.
- If symptoms persist or worsen, or if you have concerns about your condition, seek medical attention for personalized guidance and care.
- Exercising regularly helps lower the risk of heart problems.
- Maintain a healthy diet, including vegetables and fruits.
- Rest well; get enough sleep.
- Manage stress with yoga and meditation.
- Limit alcohol and smoking.
- Contact your doctor immediately if you're experiencing a fast heart rate, palpitations, or other heart-related symptoms. This is crucial to determine whether the symptoms are related to your medication.
- Your doctor may need to adjust your medication regimen to alleviate the fast heart rate symptoms. This could involve changing the medication, reducing the dosage, or adding new medications to counteract the side effects.
- Follow your doctor's advice on monitoring your heart rate and blood pressure. This will help track any changes and ensure your heart rate returns normal.
- If you experience severe symptoms such as chest pain, dizziness, or shortness of breath, seek immediate medical attention. These symptoms can indicate a more serious condition that requires prompt treatment.
- Include iron-rich foods like dark leafy vegetables, lean red meat, legumes and fish in your diet.
- Consume vitamin C-rich foods as they aid iron absorption.
- Limit tea, cocoa, and coffee as these can slow iron absorption.
- Exercise regularly; however, do not overdo it.
- Hydrate your body: Drink enough water to prevent dehydration and headaches.
- Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
- Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
- Take rest: lie down in a quiet, dark environment.
- Cold or warm compresses can help reduce tension.
- Stay Upright: Maintain good posture to keep symptoms from getting worse.
- To treat headaches naturally, try acupuncture or massage therapy.
- Over-the-counter pain relievers include acetaminophen and ibuprofen.
- Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
- Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
- Frequent Headaches: If you get reoccurring headaches, consult your doctor.
- Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
What if I have taken an overdose of XAMDEX 100MCG INJECTION
Drug Warnings
It is advisable to inform the doctor if you are allergic to any of the components of XAMDEX 100MCG INJECTION. Keep your doctor informed if you suffer from any bleeding disorders, disorders of heart rhythm, hypotension (very low blood pressure), stroke, cardiovascular disorders, neurological problems or liver disease. Consult your doctor before taking alcohol with XAMDEX 100MCG INJECTION. Inform the doctor if you are on anticoagulant (blood-thinner) therapy, sedatives, anaesthetics or any pain killers. Consult your doctor if you are pregnant, planning to get pregnant, or if you are breastfeeding as XAMDEX 100MCG INJECTION should be used with caution in these states.
Drug-Drug Interactions
Drug-Drug Interactions
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Combining Tizanidine and Xamdex 100mcg Injection can increase the risk of low blood pressure.
How to manage the interaction:
Taking Tizanidine and Xamdex 100mcg Injection together can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any symptoms like dizziness, palpitations, chest pain, or excessive sweating, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
Drug-Food Interactions
Drug-Food Interactions
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Diet & Lifestyle Advise
- Invest in a balanced diet. Load up on lean meats, fruits, green leafy vegetables, nuts, oily fish etc.
- Cut back on alcohol as this can have an adverse effect on pain states as well as the quality of your sleep.
- Try meditation and deep breathing to reduce overall stress and pain.
- Stop smoking as smoking is known to worsen pain conditions.
- Engage in mild physical exercise daily and keep your body active.
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Alcohol
Safe if prescribed
There can be a reaction of alcohol with XAMDEX 100MCG INJECTION. Use of XAMDEX 100MCG INJECTION with alcohol is hence not recommended. Please consult your doctor if you have any concerns.
Pregnancy
Consult your doctor
XAMDEX 100MCG INJECTION should be used with caution during pregnancy. Please consult your doctor if you have any concerns.
Breast Feeding
Consult your doctor
XAMDEX 100MCG INJECTION should be used with caution during breastfeeding. Please consult your doctor if you have any concerns.
Driving
Safe if prescribed
XAMDEX 100MCG INJECTION is used only in hospitalised patients. Avoid driving or operating machinery as XAMDEX 100MCG INJECTION causes sedation.
Liver
Consult your doctor
Exercise caution before using XAMDEX 100MCG INJECTION in case of liver conditions. Please consult your doctor to address any concerns.
Kidney
Consult your doctor
Exercise caution before using XAMDEX 100MCG INJECTION in case of kidney problems. Please consult your doctor to address any concerns.
Children
Safe if prescribed
XAMDEX 100MCG INJECTION is not recommended for use in children below 12 years of age. Please consult your physician if you have any concerns.
Heart
XAMDEX 100MCG INJECTION should be administered with caution in patients with heart problems. Please inform your doctor about any existing heart problems before receiving XAMDEX 100MCG INJECTION.
Geriatrics
Consult your doctor
XAMDEX 100MCG INJECTION should be administered with caution in elderly patients due to an increased risk of side effects. Seek medical advice if you have any concerns.
FAQs
XAMDEX 100MCG INJECTION belongs to the group of sedatives used to sedate patients in acute settings such as the ICU, during surgical procedures and in those who require a mechanical ventilator. Sedation is defined as a state of relaxation, drowsiness or sleep.
XAMDEX 100MCG INJECTION works by inhibiting the release of an active neurotransmitter (nerve substance) called norepinephrine and subsequently blocks pain signals.
Inform your doctor if you have high blood pressure or if you are taking blood pressure-lowering medicines as XAMDEX 100MCG INJECTION may cause alterations in blood pressure.
XAMDEX 100MCG INJECTION is not recommended for people with heart rhythm problems, and very low blood pressure that does not respond to treatment. Inform your doctor if you have heart problems, abnormally slow heart rate, or high/low blood pressure.
XAMDEX 100MCG INJECTION may cause a slow heart rate. Inform your doctor if you have an abnormally slow heart rate as XAMDEX 100MCG INJECTION may increase the risk of cardiac arrest.
No, XAMDEX 100MCG INJECTION is not a controlled substance. It is a sedative for patients in acute settings such as the ICU, during surgical procedures, and in those who require a mechanical ventilator.
Yes, XAMDEX 100MCG INJECTION is approved by the FDA in the year 1999.
In rare cases, XAMDEX 100MCG INJECTION may cause amnesia in some individuals as it has sedative and hypnotic properties, leading to memory impairment.
The common side effects of XAMDEX 100MCG INJECTION, which may occur in some individuals, include a slow heart rate, blood pressure changes, and breathing patterns. If these side effects persist, you are advised to consult your doctor.
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Reference
- https://www.researchgate.net/publication/298788377_Dexmedetomidine_Mechanism_of_Action_an_update
- https://www.medicines.org.uk/emc/files/pil.4783.pdf
- https://www.accessdata.fda.gov/drugsatfda_docs/label/2013/021038s021lbl.pdf
- https://www.ema.europa.eu/en/documents/product-information/dexdor-epar-product-information_en.pdf
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1291306/
- https://www.sciencedirect.com/topics/neuroscience/dexmedetomidine
