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  3. XAMDEX 100MCG/ML INJECTION 2ML

XAMDEX 100MCG/ML INJECTION 2ML, Pack of 1 INJECTION
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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
XAMDEX 100MCG/ML INJECTION 2ML belongs to the class of sedative and hypnotic medicines used to sedate patients in acute settings such as the ICU, during surgical procedures and in those who require a mechanical ventilator. This medicine works by inhibiting the release of norepinephrine and subsequently blocks pain signals. Common side effects include slow heart rate, a change in blood pressure and an alteration in breathing pattern.
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Composition :

DEXMEDETOMIDINE-100MCG

Manufacturer/Marketer :

Abbott India Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About XAMDEX 100MCG/ML INJECTION 2ML

XAMDEX 100MCG/ML INJECTION 2ML belongs to the group of sedatives used to sedate patients in acute settings such as the ICU, during surgical procedures and in those who require a mechanical ventilator. Sedation is defined as a state of relaxation, drowsiness or sleep.

XAMDEX 100MCG/ML INJECTION 2ML contains Dexmedetomidine which works by inhibiting the release of an active neurotransmitter (nerve substance) called norepinephrine and subsequently blocks pain signals. Hence XAMDEX 100MCG/ML INJECTION 2ML brings on a sense of relaxation and numbness through massive pain relief. 

XAMDEX 100MCG/ML INJECTION 2ML will be administered by a healthcare professional. Do not self-administer. XAMDEX 100MCG/ML INJECTION 2ML may cause certain common side effects such as a slow heart rate, a change in blood pressure and an alteration in breathing pattern. You are advised to talk to your doctor if these side effects persist. 

It is advisable to inform the doctor if you are allergic to any of the components of XAMDEX 100MCG/ML INJECTION 2ML. Consult your doctor if you are pregnant, planning to get pregnant or if you are breastfeeding, as XAMDEX 100MCG/ML INJECTION 2ML should be used with caution in these states. Avoid driving or operating machinery as XAMDEX 100MCG/ML INJECTION 2ML causes sedation. Consult your doctor before consuming alcohol with XAMDEX 100MCG/ML INJECTION 2ML.

Uses of XAMDEX 100MCG/ML INJECTION 2ML

Used for Sedation

Directions for Use

XAMDEX 100MCG/ML INJECTION 2ML will be administered by a healthcare professional. Do not self-administer.

Medicinal Benefits

XAMDEX 100MCG/ML INJECTION 2ML is a sedative that is used for the purpose of sedation in acute settings such as the intensive care unit (ICU). XAMDEX 100MCG/ML INJECTION 2ML finds application in aiding anaesthesia before surgical procedures and is also used to relax patients on mechanical ventilation. XAMDEX 100MCG/ML INJECTION 2ML contains Dexmedetomidine. XAMDEX 100MCG/ML INJECTION 2ML blocks pain signals, so the brain doesn't perceive pain or sensation and hence, brings on a sense of numbness and anaesthesia.

How XAMDEX 100MCG/ML INJECTION 2ML Works

XAMDEX 100MCG/ML INJECTION 2ML contains Dexmedetomidine which works by inhibiting the release of an active neurotransmitter (nerve substance) called norepinephrine and subsequently blocks pain signals. Hence XAMDEX 100MCG/ML INJECTION 2ML brings on a sense of relaxation and numbness through massive pain relief.

Storage

Store in a cool and dry place away from sunlight
Side effects of Xamdex 100mcg/ml Injection 2ml
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
Managing Low Blood Pressure Triggered by Medication: Expert Advice:
  • If you experience low blood pressure symptoms like dizziness, lightheadedness, or fainting while taking medication, seek immediate medical attention.
  • Make lifestyle modifications and adjust your medication regimen under medical guidance to manage low blood pressure.
  • As your doctor advises, regularly check your blood pressure at home. Record your readings to detect any changes and share them with your doctor.
  • Fluid intake plays a vital role in managing blood pressure by maintaining blood volume, regulating blood pressure, and supporting blood vessel function. Drinking enough fluids helps prevent dehydration, maintain electrolyte balance, and regulate fluid balance.
  • Take regular breaks to sit or lie down if you need to stand for long periods.
  • When lying down, elevate your head with extra pillows to help improve blood flow.
  • Avoid heavy exercise or strenuous activities that can worsen low blood pressure.
  • Wear compression socks as your doctor advises to enhance blood flow, reduce oedema, and control blood pressure.
  • If symptoms persist or worsen, or if you have concerns about your condition, seek medical attention for personalized guidance and care.
  • Exercising regularly helps lower the risk of heart problems.
  • Maintain a healthy diet, including vegetables and fruits.
  • Rest well; get enough sleep.
  • Manage stress with yoga and meditation.
  • Limit alcohol and smoking.
Here are the steps to manage the medication-triggered Tachycardia (Fast Heart Rate):
  • Contact your doctor immediately if you're experiencing a fast heart rate, palpitations, or other heart-related symptoms. This is crucial to determine whether the symptoms are related to your medication.
  • Your doctor may need to adjust your medication regimen to alleviate the fast heart rate symptoms. This could involve changing the medication, reducing the dosage, or adding new medications to counteract the side effects.
  • Follow your doctor's advice on monitoring your heart rate and blood pressure. This will help track any changes and ensure your heart rate returns normal.
  • If you experience severe symptoms such as chest pain, dizziness, or shortness of breath, seek immediate medical attention. These symptoms can indicate a more serious condition that requires prompt treatment.
  • Include iron-rich foods like dark leafy vegetables, lean red meat, legumes and fish in your diet.
  • Consume vitamin C-rich foods as they aid iron absorption.
  • Limit tea, cocoa, and coffee as these can slow iron absorption.
  • Exercise regularly; however, do not overdo it.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.

What if I have taken an overdose of XAMDEX 100MCG/ML INJECTION 2ML

Since XAMDEX 100MCG/ML INJECTION 2ML is administered by a healthcare professional, an overdose is unlikely to occur. However, seek medical attention if you experience any unusual symptoms.

Drug Warnings

It is advisable to inform the doctor if you are allergic to any of the components of XAMDEX 100MCG/ML INJECTION 2ML. Keep your doctor informed if you suffer from any bleeding disorders, disorders of heart rhythm, hypotension (very low blood pressure), stroke, cardiovascular disorders, neurological problems or liver disease. Consult your doctor before taking alcohol with XAMDEX 100MCG/ML INJECTION 2ML. Inform the doctor if you are on anticoagulant (blood-thinner) therapy, sedatives, anaesthetics or any pain killers. Consult your doctor if you are pregnant, planning to get pregnant, or if you are breastfeeding as XAMDEX 100MCG/ML INJECTION 2ML should be used with caution in these states.

Drug-Drug Interactions

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DexmedetomidineTizanidine
Severe

Drug-Drug Interactions

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DexmedetomidineTizanidine
Severe
How does the drug interact with Xamdex 100mcg/ml Injection 2ml:
Combining Tizanidine and Xamdex 100mcg/ml Injection 2ml can increase the risk of low blood pressure.

How to manage the interaction:
Taking Tizanidine and Xamdex 100mcg/ml Injection 2ml together can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any symptoms like dizziness, palpitations, chest pain, or excessive sweating, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Invest in a balanced diet. Load up on lean meats, fruits, green leafy vegetables, nuts, oily fish etc. 
  • Cut back on alcohol as this can have an adverse effect on pain states as well as the quality of your sleep.
  • Try meditation and deep breathing to reduce overall stress and pain. 
  • Stop smoking as smoking is known to worsen pain conditions. 
  • Engage in mild physical exercise daily and keep your body active. 

Habit Forming

No

Therapeutic Class

SEDATIVES AND HYPNOTICS

XAMDEX 100MCG/ML INJECTION 2ML Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Unsafe

There can be a reaction of alcohol with XAMDEX 100MCG/ML INJECTION 2ML. Use of XAMDEX 100MCG/ML INJECTION 2ML with alcohol is hence not recommended. Please consult your doctor if you have any concerns.

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Pregnancy

Caution

XAMDEX 100MCG/ML INJECTION 2ML should be used with caution during pregnancy. Please consult your doctor if you have any concerns.

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Breast Feeding

Caution

XAMDEX 100MCG/ML INJECTION 2ML should be used with caution during breastfeeding. Please consult your doctor if you have any concerns.

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Driving

Unsafe

XAMDEX 100MCG/ML INJECTION 2ML is used only in hospitalised patients. Avoid driving or operating machinery as XAMDEX 100MCG/ML INJECTION 2ML causes sedation.

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Liver

Caution

Exercise caution before using XAMDEX 100MCG/ML INJECTION 2ML in case of liver conditions. Please consult your doctor to address any concerns.

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Kidney

Caution

Exercise caution before using XAMDEX 100MCG/ML INJECTION 2ML in case of kidney problems. Please consult your doctor to address any concerns.

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Children

Unsafe

XAMDEX 100MCG/ML INJECTION 2ML is not recommended for use in children below 12 years of age. Please consult your physician if you have any concerns.

Have a query?

FAQs

XAMDEX 100MCG/ML INJECTION 2ML belongs to the group of sedatives used to sedate patients in acute settings such as the ICU, during surgical procedures and in those who require a mechanical ventilator. Sedation is defined as a state of relaxation, drowsiness or sleep.

XAMDEX 100MCG/ML INJECTION 2ML works by inhibiting the release of an active neurotransmitter (nerve substance) called norepinephrine and subsequently blocks pain signals.

Inform your doctor if you have high blood pressure or if you are taking blood pressure-lowering medicines as XAMDEX 100MCG/ML INJECTION 2ML may cause alterations in blood pressure.

XAMDEX 100MCG/ML INJECTION 2ML is not recommended for people with heart rhythm problems, and very low blood pressure that does not respond to treatment. Inform your doctor if you have heart problems, abnormally slow heart rate, or high/low blood pressure.

XAMDEX 100MCG/ML INJECTION 2ML may cause a slow heart rate. Inform your doctor if you have an abnormally slow heart rate as XAMDEX 100MCG/ML INJECTION 2ML may increase the risk of cardiac arrest.

No, XAMDEX 100MCG/ML INJECTION 2ML is not a controlled substance. It is a sedative for patients in acute settings such as the ICU, during surgical procedures, and in those who require a mechanical ventilator.

Yes, XAMDEX 100MCG/ML INJECTION 2ML is approved by the FDA in the year 1999.

In rare cases, XAMDEX 100MCG/ML INJECTION 2ML may cause amnesia in some individuals as it has sedative and hypnotic properties, leading to memory impairment.

The common side effects of XAMDEX 100MCG/ML INJECTION 2ML, which may occur in some individuals, include a slow heart rate, blood pressure changes, and breathing patterns. If these side effects persist, you are advised to consult your doctor.

Country of origin

India

Manufacturer/Marketer address

16th Floor, Godrej BKC, Plot – C, “G” Block, Bandra-Kurla Complex, Bandra (East), Mumbai – 400 051, India
Other Info - XAM0006

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Author Details

Veda MaddalaDoctor badge

Written By

Veda Maddala

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jan 1, 2025 | 2:46 PM IST

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Reference

  1. https://www.researchgate.net/publication/298788377_Dexmedetomidine_Mechanism_of_Action_an_update
  2. https://www.medicines.org.uk/emc/files/pil.4783.pdf
  3. https://www.accessdata.fda.gov/drugsatfda_docs/label/2013/021038s021lbl.pdf
  4. https://www.ema.europa.eu/en/documents/product-information/dexdor-epar-product-information_en.pdf
  5. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1291306/
  6. https://www.sciencedirect.com/topics/neuroscience/dexmedetomidine
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