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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Xoten A 10/75mgmg Capsule is a combination medication that contains Rosuvastatin (a statin) and Clopidogrel (an antiplatelet). It helps prevent heart attacks, strokes, and chest pain (angina) by lowering bad cholesterol and fats in the blood and preventing blood clots. Common side effects may include headache, nausea, ankle swelling, and a slow heartbeat. Take this medicine exactly as prescribed. Tell your doctor if you have liver problems, bleeding issues, or if you're pregnant, breastfeeding, or taking other blood thinners. Avoid drinking alcohol while on this medication.

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Manufacturer/Marketer :

Alteus Biogenics Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Xoten A 10/75mgmg Capsule

Xoten A 10/75mgmg Capsule is a combination of two types of medicines: a statin and an antiplatelet. It is used to help prevent heart attacks, strokes, and chest pain (angina) in people who are at high risk of heart problems. A heart attack happens when the coronary arteries, blood vessels that supply blood and oxygen to the heart, become blocked by fatty deposits (plaques), including cholesterol. These plaques narrow the arteries, leading to atherosclerosis and coronary artery disease, which are the leading causes of most heart attacks.

Xoten A 10/75mgmg Capsule contains two active ingredients that work together to protect your heart. Rosuvastatin lowers cholesterol production in the liver. It reduces bad cholesterol (LDL) and triglycerides (TG) while increasing good cholesterol (HDL). Clopidogrel is an antiplatelet medicine (blood thinner) that prevents blood cells (platelets) from clumping together and forming clots. Together, these medicines improve blood flow and reduce the risk of blocked arteries, helping prevent serious heart and brain complications.

Take Xoten A 10/75mgmg Capsule exactly as prescribed by your doctor, usually once a day with or without food. Do not skip doses or stop taking the medicine without consulting a doctor. Common side effects may include headache, nausea, dizziness, swollen ankles (oedema), and in rare cases, slow heart rate. Most side effects are mild and go away on their own, but contact your doctor if they persist or worsen. If you miss a dose, take it as soon as you remember. If it’s almost time for your next dose, skip the missed one. Do not take two doses at the same time.

Do not stop taking Xoten A 10/75mgmg Capsule without consulting your doctor, as stopping it suddenly may increase your risk of heart attack or stroke. Please inform your doctor of any medical conditions or allergies you may have before starting Xoten A 10/75mgmg Capsule . Always inform your doctor that you are taking Xoten A 10/75mgmg Capsule before any surgery or if a new medicine is prescribed. Xoten A 10/75mgmg Capsule should not be used during pregnancy or breastfeeding, as it may harm the baby. It is also not recommended for use in children below 10 years.

Uses of Xoten A 10/75mgmg Capsule

Xoten A 10/75mgmg Capsule is used to reduce the risk of serious heart and blood vessel problems in people at high risk of cardiovascular disease. It is commonly prescribed for:

  • Prevention of heart attacks: It helps lower LDL (bad) cholesterol and reduces the formation of blood clots that could block the coronary arteries.
  • Prevention of strokes: It improves blood flow to the brain and decreases the risk of clot-related (thrombotic) events.
  • Management of chest pain (angina): It enhances the blood supply to the heart muscles, relieving chest pain and discomfort caused by reduced blood flow.
  • Slowing the progression of atherosclerosis: It reduces the buildup of cholesterol and plaque in blood vessels, helping to maintain healthy arteries.
  • Secondary prevention of cardiovascular events: It is used in people who have already had a heart attack, stroke, or undergone heart procedures such as angioplasty or bypass surgery to help prevent future events.

Directions for Use

  • Take Xoten A 10/75mgmg Capsule with or without food as advised by your doctor.
  • It is recommended to follow your doctor’s recommendations regarding the dosage and duration.
  • Swallow it as a whole with a glass of water.
  • Do not crush, chew or break it.

Medicinal Benefits

  • Xoten A 10/75mgmg Capsule effectively reduces the risk of heart attacks and strokes by lowering bad cholesterol and preventing blood clots.
  • Slows the progression of atherosclerosis, helping keep arteries open and reducing cardiovascular strain.
  • Provides dual protection. Rosuvastatin stabilises cholesterol plaques, while Clopidogrel prevents clot formation on them.
  • Improves long-term cardiovascular outcomes in patients with coronary artery disease or those who’ve had angioplasty or bypass surgery.
  • Lowers the chance of future cardiovascular events in high-risk individuals or those with a history of heart attack or stroke.

How Xoten A 10/75mgmg Capsule Works

Xoten A 10/75mgmg Capsule is a combination of two medications, Rosuvastatin and Clopidogrel, used to reduce the risk of heart attack, stroke, and other cardiovascular events. Rosuvastatin is a statin that lowers cholesterol by inhibiting the HMG-CoA reductase enzyme, thereby reducing levels of LDL (bad cholesterol) and triglycerides while increasing HDL (good cholesterol). Clopidogrel is an antiplatelet agent that prevents blood platelets from clumping together, helping to reduce the risk of harmful blood clots. Together, they work to manage high cholesterol and prevent clot-related complications, offering comprehensive protection against serious heart and blood vessel conditions.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if I have taken an overdose of Xoten A 10/75mgmg Capsule

Do not take more than the prescribed dose. Using more medication will not improve your symptoms; rather, they may cause poisoning or serious side effects. If you suspect that you may have overdosed of Xoten A 10/75mgmg Capsule or if you experience any adverse events, please go to the emergency department of the closest hospital.

Drug Warnings

  • Do not take Xoten A 10/75mgmg Capsule if you are allergic to any of its ingredients.
  • Do not use Xoten A 10/75mgmg Capsule if you are pregnant, planning to become pregnant, or breastfeeding, as Rosuvastatin may harm the unborn baby and is strictly contraindicated during pregnancy.
  • Avoid Xoten A 10/75mgmg Capsule if you have active liver disease or any active bleeding conditions, such as stomach ulcers or brain haemorrhage, unless specifically advised by your doctor.
  • Inform your doctor about all medications you are taking, especially antibiotics (like clarithromycin), antifungals (like itraconazole), HIV medicines, or blood thinners like warfarin, due to the risk of serious interactions.
  • Tell your doctor you are taking Xoten A 10/75mgmg Capsule before any surgery or if a new medicine is being prescribed, to avoid potential complications or interactions.
  • Do not stop taking Xoten A 10/75mgmg Capsule suddenly without medical advice, as this may increase the risk of heart attack, stroke, or other serious cardiovascular events.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Xoten A 10/75mgmg Capsule:
Taking Xoten A 10/75mgmg Capsule together with mifepristone increases the risk of vaginal bleeding in women.

How to manage the interaction:
Although taking Xoten A 10/75mgmg Capsule with mifepristone is not recommended, that would certainly result in interaction, it can be taken if a doctor prescribes it. If you experience prolonged and heavy bleeding, consult a doctor immediately. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Xoten A 10/75mgmg Capsule:
When Selexipag and Xoten A 10/75mgmg Capsule are taken together, the body's ability to break down Selexipag may be reduced.

How to manage the interaction:
Taking Xoten A 10/75mgmg Capsule with Selexipag is not recommended, please consult your doctor before taking it. They can be taken if prescribed by your doctor.
How does the drug interact with Xoten A 10/75mgmg Capsule:
Co-administration of Xoten A 10/75mgmg Capsule with lenalidomide may increase the risk of a rare condition called rhabdomyolysis (breakdown of skeletal muscle tissue).

How to manage the interaction:
Although there is an interaction between lenalidomide and Xoten A 10/75mgmg Capsule, it can be taken if prescribed by a doctor. However, if you experience muscle pain, tenderness, or weakness, consult the doctor immediately. Do not discontinue any medications without consulting a doctor.
RosuvastatinSimeprevir
Severe
How does the drug interact with Xoten A 10/75mgmg Capsule:
Co-administration of Simeprevir and Xoten A 10/75mgmg Capsule can increase the blood levels of Xoten A 10/75mgmg Capsule and can increase the risk of side effects like liver damage and rhabdomyolysis( breakdown of skeletal muscle tissue).

How to manage the interaction:
Co-administration of Simeprevir and Xoten A 10/75mgmg Capsule can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like muscle pain, tenderness, weakness, dark-colored urine, fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, and yellowing of the skin or eyes, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Xoten A 10/75mgmg Capsule:
Co-administration of Gemfibrozil and Xoten A 10/75mgmg Capsule may increase the risk or severity of side effects like muscle injury.

How to manage the interaction:
Co-administration of Gemfibrozil and Xoten A 10/75mgmg Capsule can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like muscle pain, tenderness, weakness, or dark-colored urine, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Xoten A 10/75mgmg Capsule:
Co-administration of leflunomide and Xoten A 10/75mgmg Capsule can increase the risk of developing liver problems.

How to manage the interaction:
Co-administration of Leflunomide and Xoten A 10/75mgmg Capsule can lead to an interaction, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Xoten A 10/75mgmg Capsule:
Coadministration of colchicine and Xoten A 10/75mgmg Capsule may increase the risk of conditions that affect your muscles and kidneys.

How to manage the interaction:
Taking Colchicine with Xoten A 10/75mgmg Capsule may possibly result in an interaction, but they can be taken together if prescribed by your doctor. However, contact your doctor immediately if you experience abdominal discomfort, nausea, vomiting, diarrhea, back pain, weakness, or tingling or numbness in your hands and feet. Do not discontinue any medication without consulting your doctor.
How does the drug interact with Xoten A 10/75mgmg Capsule:
Co-administration of Xoten A 10/75mgmg Capsule and Atazanavir can increase the blood levels of Xoten A 10/75mgmg Capsule and can increase the risk of liver damage and rhabdomyolysis( breakdown of skeletal muscle tissue).

How to manage the interaction:
Co-administration of Xoten A 10/75mgmg Capsule and Atazanavir can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like muscle pain, tenderness, weakness, dark-colored urine, fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, and yellowing of the skin or eyes, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Xoten A 10/75mgmg Capsule:
Co-administration of Ritonavir and Xoten A 10/75mgmg Capsule can increase the blood levels of Xoten A 10/75mgmg Capsule.

How to manage the interaction:
Co-administration of Ritonavir and Xoten A 10/75mgmg Capsule can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like muscle pain, tenderness, weakness, dark-colored urine, fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of hunger, weakness, nausea, vomiting, and yellowing of the skin or eyes, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Xoten A 10/75mgmg Capsule:
Taking Xoten A 10/75mgmg Capsule with clopidogrel can increase the blood levels of Xoten A 10/75mgmg Capsule. This can increase the risk of side effects.

How to manage the interaction:
Although taking clopidogrel together with Xoten A 10/75mgmg Capsule may result in an interaction, it can be taken if prescribed by your doctor. However, consult your doctor immediately if you experience chills, joint pain or swelling, skin rash, itching, nausea, vomiting, dark-colored urine, and/or yellowing of the skin or eyes. Do not discontinue any medication without consulting your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Follow a Mediterranean or DASH diet rich in vegetables, fruits, whole grains, legumes, nuts, and healthy fats, such as olive oil, which has been shown to reduce the risk of cardiovascular events.
  • Limit your intake of saturated fats and eliminate trans fats to lower LDL cholesterol and reduce your risk of atherosclerosis.
  • Reduce sodium intake to less than 2,300 mg per day to help control blood pressure and lower the risk of stroke and heart disease.
  • Engage in at least 150 minutes of moderate aerobic exercise per week, such as brisk walking, swimming, or cycling, to improve heart health and cholesterol levels.
  • Quit smoking and avoid secondhand smoke exposure, as tobacco significantly increases the risk of clot formation and arterial damage.
  • Limit alcohol consumption to no more than one standard drink per day for women and two for men, as excessive alcohol raises blood pressure and cardiovascular risk.
  • Maintain a healthy weight (BMI 18.5–24.9); even modest weight loss improves cholesterol, blood pressure, and blood sugar control.
  • Manage blood sugar effectively, especially in patients with diabetes, to prevent accelerated vascular damage and cardiovascular complications.
  • Reduce chronic stress through techniques like mindfulness, relaxation, or yoga, and aim for 7–8 hours of quality sleep to support overall cardiovascular health.
  • Take medications like Rosuvastatin and Clopidogrel exactly as prescribed, and attend regular medical check-ups to monitor lipid levels, clotting function, and overall cardiovascular risk.

Habit Forming

No

Therapeutic Class

ANTICOAGULANT/ANTITHROMBOTIC
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Alcohol

Unsafe

Xoten A 10/75mgmg Capsule should not be taken with alcohol as it may worsen your liver condition with increased secretion of liver enzymes like transaminase. Keep your doctor informed if you drink alcohol.

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Pregnancy

Unsafe

Xoten A 10/75mgmg Capsule contains Rosuvastatin, which is a pregnancy category X medicine. It may cause harm to both the pregnant mother and the fetus. Hence, it is not recommended for pregnant women and those who are planning for a pregnancy. Your doctor may prescribe it only in extreme cases.

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Breast Feeding

Caution

Take Xoten A 10/75mgmg Capsule only when prescribed, it is known to pass on in a limited quantity via breast milk to the child.

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Driving

Caution

Drive with caution, Xoten A 10/75mgmg Capsule usually causes blurry vision and may affect driving ability.

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Liver

Caution

Xoten A 10/75mgmg Capsule to be taken with caution, especially if you have a history of liver diseases/conditions. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Xoten A 10/75mgmg Capsule to be taken with caution, especially if you have a history of kidney diseases/conditions. The dose may have to be adjusted by your doctor.

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Children

Caution

Xoten A 10/75mgmg Capsule is not recommended for children below the age of 10 years. The safety and effectiveness of Xoten A 10/75mgmg Capsule have not been established in children due to limited testing of Xoten A 10/75mgmg Capsule on children by competent authorities worldwide.

Have a query?

FAQs

Xoten A 10/75mgmg Capsule is used to prevent heart attacks and strokes in the future. It lowers the raised level of cholesterol and fats (triglycerides) in the body.

Xoten A 10/75mgmg Capsule is composed of two medicines, namely: Rosuvastatin and Clopidogrel. Rosuvastatin is a lipid-lowering medication that inhibits the enzyme responsible for producing cholesterol in the body. As a result, it lowers the bad cholesterol (low-density lipoproteins or LDL) and triglycerides (TG), and increases the levels of good cholesterol (high-density lipoproteins or HDL). Clopidogrel is a blood thinner (anticoagulant) that collectively prevents the formation of clots in the blood vessels. Together, Xoten A 10/75mgmg Capsule reduces the increased levels of bad cholesterol (low-density lipoprotein and triglycerides) and prevents blood clots, thereby reducing the risk of heart attack, stroke, and heart-related chest pain (angina).

Yes, Xoten A 10/75mgmg Capsule contains clopidogrel that prevents blood clotting. It works by preventing platelets (a type of blood cell) from sticking together and forming clots, thereby preventing heart attacks and strokes.

No, Xoten A 10/75mgmg Capsule contains Rosuvastatin, pregnancy category X medicine, and can harm both pregnant mother and unborn baby. Even if you are planning for pregnancy, tell your doctor that you are using Xoten A 10/75mgmg Capsule .

If you accidentally take an overdose of Xoten A 10/75mgmg Capsule , you may have liver problems (increased secretion of liver enzymes) and bleeding complications. If problems persist, please go to the nearest clinic or hospital immediately.

It would be best if you had total lipid profile (TG, HDL, LDL, VLDL, TC) and Blood coagulation tests like Complete blood count (CBC), Factor V assay, Fibrinogen Test, Prothrombin time (PT or PT-INR), Platelet count, Thrombin time and Bleeding time to analyze your blood clot timing and cholesterol level.

Do not drink grapefruit juice while taking Xoten A 10/75mgmg Capsule . Grapefruit juice may increase the blood-thinning effect of your medicine.

Yes, prolonged use of Xoten A 10/75mgmg Capsule may cause muscle diseases like myopathy and rhabdomyolysis. So if you feel any musculoskeletal pain after taking Xoten A 10/75mgmg Capsule , consult your doctor about this issue.

Yes, taking Xoten A 10/75mgmg Capsule can increase bleeding risk as it contains aspirin and clopidogrel, which belong to a class of blood-thinning agents. Therefore, please exercise caution when shaving, cutting fingernails or toenails, or using sharp objects to prevent bleeding. Before undergoing any surgical procedure, please inform your doctor that you are taking Xoten A 10/75mgmg Capsule .

Consult your doctor before taking other medications while on treatment with Xoten A 10/75mgmg Capsule to prevent any potential interactions. Let the doctor know if you are taking antibiotics, anti-HIV drugs, antifungal, blood thinners, anti-arthritis medicines, oral contraceptives, cardiac medicines or immunosuppressants.

If you are due to undergo any surgery or dental procedure, inform the doctor that you are taking Xoten A 10/75mgmg Capsule . The doctor might ask you to stop Xoten A 10/75mgmg Capsule before surgery as it might increase the risk of bleeding.

Follow a healthy diet and exercise regularly. Avoid smoking and alcohol consumption. Manage stress by doing meditation. Be cautious while using sharp objects.

It might be safe to use paracetamol while taking Xoten A 10/75mgmg Capsule as other painkillers may increase the risk of bleeding. However, consult the doctor before using any painkiller medicines.

Side effects of Xoten A 10/75mgmg Capsule include headaches, ankle swelling due to fluid retention (oedema), slow heart rate, and nausea. If the side effects are persistent, reach out to your doctor.

Country of origin

INDIA

Manufacturer/Marketer address

Alteus Biogenics Pvt. Ltd., 14-B Dover Lane, Kolkata - 700029, WB, India.
Other Info - XOT0007

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