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  1. Home
  2. Medicine

  3. Yesom 40 mg Injection 1's

Prescription drug
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Yesom 40 mg Injection 1's, Pack of 1 Injection
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Extra 15% Off with Bank Offers

Composition :

ESOMEPRAZOLE-40MG

Manufacturer/Marketer :

Hetero Healthcare Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Yesom 40 mg Injection

Yesom 40 mg Injection belongs to the class of drugs known as proton pump inhibitors, used for the short-term treatment of gastroesophageal reflux disease (GERD) and stomach ulcers caused by NSAIDs. It also reduces the risk of further ulcer bleeding following an endoscopy in adults.

Yesom 40 mg Injection is indicated in adults and children aged 1 month or older who have had damage to their oesophagus and are unable to take esomeprazole by mouth.

Yesom 40 mg Injection contains 'Esomeprazole' that works by reducing the amount of acid made in the stomach. As a result, it relieves symptoms of gastroesophageal reflux disease (GERD) and stomach ulcers.

In some cases, Yesom 40 mg Injection may cause headache, diarrhoea, stomach pain, constipation, wind (flatulence), nausea, vomiting, and injection site reactions such as pain, itching, swelling or redness. Most of these side effects do not require medical attention and may resolve with time. However, if they persist or worsen, consult a doctor.

Do not take Yesom 40 mg Injection if you have/had any allergy or hypersensitivity to esomeprazole, any other proton pump inhibitor medications (such as pantoprazole, lansoprazole, rabeprazole, or omeprazole), or any of the other ingredients in Yesom 40 mg Injection. Consult your doctor if you are breastfeeding, pregnant, or intend to become pregnant.

Uses of Yesom 40 mg Injection

Yesom 40 mg Injection is used for short-term treatment of acid-related disorders. The detailed uses of Yesom 40 mg Injection are as follows:

  • Gastroesophageal reflux disease (GERD): Yesom 40 mg Injection is used to treat acid reflux in adults and children aged 1 to 18 years, reducing symptoms such as heartburn, irritation, and pain.
  • Management of stomach ulcers caused by NSAIDs: Yesom 40 mg Injection is used to treat pre-existing ulcers caused by nonsteroidal anti-inflammatory medications.
  • Prevention of NSAID-associated ulcers: Yesom 40 mg Injection helps prevent ulcer formation in individuals who need long-term NSAID medication.
  • Prevention of rebleeding in gastric or duodenal ulcers: Yesom 40 mg Injection is used after endoscopic therapy to prevent bleeding from stomach or upper intestine ulcers.

Have a query?

Directions for Use

  • Follow your doctor’s instructions on the dosage and timing of this medication to ensure safe and effective use.
  • Yesom 40 mg Injection will be administered by the doctor or healthcare professional.
  • Do not self-administer.

Medicinal Benefits

  • Yesom 40 mg Injection contains Esomeprazole, a proton pump inhibitor (PPI) that effectively reduces stomach acid production.
  • It is used to treat gastroesophageal reflux disease (GERD), relieving symptoms like heartburn, acid regurgitation, and discomfort.
  • Yesom 40 mg Injection helps heal stomach and duodenal ulcers, including those caused by NSAID use, promoting gastrointestinal health.
  • It is also used to reduce the risk of further ulcer bleeding following an endoscopy in adults.
  • By blocking the proton pump that secretes stomach acid, Yesom 40 mg Injection provides relief from acidity-related conditions and prevents damage to the stomach and oesophageal lining.

How Yesom 40 mg Injection Works

Yesom 40 mg Injection contains 'Esomeprazole' that works by reducing the amount of acid made in the stomach. As a result, it relieves symptoms of gastroesophageal reflux disease (GERD) and stomach ulcers.

Storage

• Store in a cool and dry place away from sunlight.• Keep out of sight and reach of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Yesom 40 mg Injection
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the steps to manage Gastrointestinal Air and Swelling (GAS) caused by medication:
  • Tell your doctor about your GAS symptoms. They may change your medication regimen or prescribe additional drugs to help you manage them.
  • To manage GAS symptoms, eat a balanced diet of fibre, vegetables, and fruits.
  • Drink enough water throughout the day to avoid constipation and treat GAS symptoms.
  • Regular exercise like yoga and walking may help stimulate digestion and alleviate GAS symptoms.
  • Take probiotics only if your doctor advises, as they may help alleviate GAS symptoms by promoting gut health.
  • Take medication for GAS symptoms only if your doctor advises, as certain medications can interact with your existing prescriptions or worsen symptoms.
  • If symptoms persist, worsen, or are accompanied by severe abdominal pain, vomiting, or bleeding, seek immediate medical attention.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
Here are the steps to manage the medication-triggered Cough:
  • Tell your doctor about the cough symptoms you're experiencing, which may be triggered by your medication.
  • Your doctor may adjust your treatment plan by changing your medication, adding new medications, or providing guidance on managing your cough symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Stay hydrated by drinking plenty of fluids, such as water, tea, or soup, to help thin out mucus and soothe your throat.
  • Get plenty of rest and engage in stress-reducing activities to help your body recover. If your cough persists or worsens, consult your doctor for further guidance.
Here are the few steps for dealing with itching caused by drug use:
  • Report the itching to your doctor immediately; they may need to change your medication or dosage.
  • Use a cool, damp cloth on the itchy area to help soothe and calm the skin, reducing itching and inflammation.
  • Keep your skin hydrated and healthy with gentle, fragrance-free moisturizers.
  • Try not to scratch, as this can worsen the itching and irritate your skin.
  • If your doctor prescribes, you can take oral medications or apply topical creams or ointments to help relieve itching.
  • Track your itching symptoms and follow your doctor's guidance to adjust your treatment plan if needed. If the itching persists, consult your doctor for further advice.

What if I have taken an overdose of Yesom 40 mg Injection

A healthcare professional administers Yesom 40 mg Injection in a hospital setting. Hence, the chances of overdose are less. If you experience stomach cramps, bloating, watery, severe diarrhoea that occasionally turns bloody, fever, nausea, vomiting, or unusual weakness or tiredness, consult your doctor right away.

Drug Warnings

  • Avoid taking Yesom 40 mg Injection if you are allergic to any of its components.
  • Inform your doctor if you are taking other proton pump inhibitors or if you are taking certain HIV medications such as nelfinavir.
  • Consult your doctor if you are a pregnant woman/nursing mother.
  • Let your doctor know if you have liver/kidney problems or if you are due to undergo a Chromogranin A test.
  • Taking Yesom 40 mg Injection for more than a year may modestly raise your risk of hip, wrist, or spine fracture.
  • If you use corticosteroids (which can increase the risk of osteoporosis) or have osteoporosis, tell your doctor.
  • Keep your doctor informed about your health condition and all the medicines you take to rule out any side effects/interactions.

Drug-Drug Interactions

verifiedApollotooltip
EsomeprazoleRilpivirine
Critical
EsomeprazoleGefitinib
Severe

Drug-Drug Interactions

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EsomeprazoleRilpivirine
Critical
How does the drug interact with Yesom 40 mg Injection:
Yesom 40 mg Injection may reduce rilpivirine absorption and blood levels, making the medicine less effective against HIV.

How to manage the interaction:
Although taking Yesom 40 mg Injection with Rilpivirine can possibly result in an interaction, they can be taken together if prescribed by your doctor. However, contact your doctor immediately if your symptoms do not improve. Do not discontinue using any medications without consulting a doctor.
EsomeprazoleGefitinib
Severe
How does the drug interact with Yesom 40 mg Injection:
Taking gefitinib with Yesom 40 mg Injection may reduce the effectiveness of gefitinib.

How to manage the interaction:
Although taking Yesom 40 mg Injection and Gefitinib together can possibly result in an interaction, they can be taken together if prescribed by your doctor. It is recommended to take Gefitionib 12 hours before or after taking Yesom 40 mg Injection. Do not stop taking any medications without consulting a doctor.
EsomeprazoleTacrolimus
Severe
How does the drug interact with Yesom 40 mg Injection:
Taking tacrolimus with Yesom 40 mg Injection may significantly increase the blood levels of tacrolimus, which can lead to an increased risk of side effects.

How to manage the interaction:
Although taking Yesom 40 mg Injection with Tacrolimus can result in an interaction, they can be taken together if prescribed by your doctor. However, contact a doctor immediately if you experience irregular heartbeat, blurring of vision, fever, chills, or muscle spasms. Do not discontinue any medications without consulting a doctor.
EsomeprazoleCitalopram
Severe
How does the drug interact with Yesom 40 mg Injection:
Combining Yesom 40 mg Injection with Citalopram can increase the risk of irregular heart rhythm. .

How to manage the interaction:
Co-administration of Yesom 40 mg Injection with Citalopram can possibly result in an interaction, but it can be taken if your doctor has advised it. If you're having any symptoms like irregular heart rhythm, dizziness, fainting, or shortness of breath, it's important to contact your doctor immediately. Do not stop using any medications without a doctor's advice.
EsomeprazoleDasatinib
Severe
How does the drug interact with Yesom 40 mg Injection:
Using Dasatinib together with Yesom 40 mg Injection may decrease the levels of Dasatinib.

How to manage the interaction:
Although taking Yesom 40 mg Injection together with Dasatinib can result in an interaction, they can be taken together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
EsomeprazoleDacomitinib
Severe
How does the drug interact with Yesom 40 mg Injection:
Yesom 40 mg Injection can make Dacomitinib less effective by reducing its absorption and lowering its concentration in the blood.

How to manage the interaction:
Co-administration of Yesom 40 mg Injection with Dacomitinib can result in an interaction, but it can be taken if your doctor has advised it. Do not stop using any medications without talking to your doctor.
EsomeprazoleAcalabrutinib
Severe
How does the drug interact with Yesom 40 mg Injection:
Yesom 40 mg Injection may interfere with the absorption of Acalabrutinib and reduce their efficacy.

How to manage the interaction:
Taking Yesom 40 mg Injection with Acalabrutinib together can result in an interaction, but it can be taken if your doctor has advised it. Do not stop using any medications without talking to your doctor.
EsomeprazoleMethotrexate
Severe
How does the drug interact with Yesom 40 mg Injection:
Co-administration of methotrexate and Yesom 40 mg Injection can increase the blood levels and side effects of methotrexate.

How to manage the interaction:
Although taking Yesom 40 mg Injection with Methotrexate can result in an interaction, they can be taken together if prescribed by a doctor. However, contact your doctor if you experience headache, dizziness, nausea and vomiting. Do not discontinue any medications without consulting a doctor.
EsomeprazoleClopidogrel
Severe
How does the drug interact with Yesom 40 mg Injection:
Coadministration of Clopidogrel with Yesom 40 mg Injection may reduce the effectiveness of clopidogrel.

How to manage the interaction:
Taking clopidogrel and Yesom 40 mg Injection together possibly has an interaction, but you can take these medications together if your doctor has advised it. Do not stop using any medications without talking to your doctor.
EsomeprazoleErlotinib
Severe
How does the drug interact with Yesom 40 mg Injection:
Coadministration of erlotinib and Yesom 40 mg Injection can reduce effects of erlotinib.

How to manage the interaction:
Taking Erlotinib and Yesom 40 mg Injection together is generally avoided as it can possibly result in an interaction. It can be taken if your doctor has advised it. Do not stop using any medications without first talking to your doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Avoid intake of acid or heartburn-triggering foods or drinks like onions, peppermint, chocolate, caffeinated beverages, citrus fruits or juices, tomatoes, high-fat and spicy foods.
  • Before going to sleep, try to raise your bedhead so that your head and chest are higher than your feet. Do not use piles of pillows. Instead, one raised block is fine. This will not allow the stomach acid to backflow through your food pipe.
  • Avoid alcohol and smoking. Alcohol can raise the production of stomach acid, leading to heartburn and acid reflux. On the other hand, smoking damages the sphincter, which prevents backflow of the stomach acid back into the food pipe.
  • Include high fibre-containing foods, berries, cherries, leafy green vegetables (kale, spinach) and black pepper in your meal. These foods are full of antioxidants, calcium and vitamin B 12 that can help cope with the long-term effects of the medicine.
  • Fermented dairy products like miso, sauerkraut, and kimchi contain probiotics, which help prevent excess stomach acid production. Cranberry juice can be beneficial for peptic ulcers and H pylori infection.
  • Avoid sitting continuously, as it can increase stomach acid production. Take a 5-minute break each hour by brisk walking or stretching.

Habit Forming

No

Therapeutic Class

ANTACIDS

Yesom 40 mg Injection Substitute

Substitutes safety advice
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Alcohol

Caution

Drinking alcohol or alcoholic beverages with Yesom 40 mg Injection may cause dehydration and elevate the level of stomach acid thereby decreasing its efficiency. So try to avoid/limit alcohol.

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Pregnancy

Caution

Consult a doctor if you are pregnant. Your doctor will weigh the benefits and potential risks before prescribing Yesom 40 mg Injection.

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Breast Feeding

Caution

Consult a doctor if you are breastfeeding. Your doctor will weigh the benefits and potential risks before prescribing Yesom 40 mg Injection.

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Driving

Caution

In rare cases, Yesom 40 mg Injection may cause dizziness and impaired vision. Do not drive if you experience these symptoms.

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Liver

Caution

Yesom 40 mg Injection should be taken with precaution in patients with liver disease. Inform your doctor before receiving Yesom 40 mg Injection if you have had a liver impairment/disorder history. The doctor will prescribe only if the benefits outweigh the risks.

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Kidney

Caution

Yesom 40 mg Injection should be taken with precaution in patients with kidney disease. Inform your doctor before receiving Yesom 40 mg Injection if you have had a history of severe kidney impairment/disorder. The doctor will prescribe only if the benefits outweigh the risks.

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Children

Safe if prescribed

Yesom 40 mg Injection can be given to children aged 1 month or older under the supervision of a healthcare provider.

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Heart

Yesom 40 mg Injection should be administered with caution in patients with heart problems. Therefore, please inform your doctor before receiving Yesom 40 mg Injection.

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Geriatrics

Caution

Yesom 40 mg Injection should be administered with caution in elderly patients due to an increased risk of side effects. Seek medical advice if you have any concerns.

FAQs

Yesom 40 mg Injection belongs to the class of drugs known as proton pump inhibitors, used for the short-term treatment of gastroesophageal reflux disease (GERD) and stomach ulcers caused by NSAIDs. It also reduces the risk of further ulcer bleeding following an endoscopy in adults.

Yesom 40 mg Injection impairs the function of proton pumps. This decreases the quantity of acid produced by the stomach, thereby helping treat GERD.

No. Gas and acidity are two different conditions. Acidity is caused by improper functioning of the valve (sphincter) located at the junction of the stomach and the food pipe. As a result, stomach acid backflows and enters the upper part of the food pipe, causing heartburn. On the other hand, gas is the result of the digestion of food and drinks, eliminating gases like carbon dioxide, hydrogen, nitrogen, methane, etc., from the body.

On long-term treatment, Yesom 40 mg Injection may cause low magnesium levels. Low magnesium levels can make you tired, confused, and dizzy and cause muscle cramps, shakiness, and an irregular heartbeat. Inform the doctor if you experience any of these symptoms.

Yesom 40 mg Injection may alter certain medical tests, like secretin stimulation tests and urine screening tests for tetrahydrocannabinol (THC). So, if you are undergoing diagnostic tests, inform your doctor that you are taking Yesom 40 mg Injection.

Yesom 40 mg Injection may slightly increase the risk of hip, wrist, or spine fracture, especially if you take it for longer than a year. Let your doctor know if you have osteoporosis or are taking corticosteroids (which can increase the risk of osteoporosis).

Country of origin

India
Other Info - YES0066

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Santoshini Reddy GDoctor badge

Reviewed By

Santoshini Reddy G

M Pharmacy

Last Updated

Oct 14, 2025 | 1:09 PM IST

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Reference

  1. https://www.medicines.org.uk/emc/files/pil.4095.pdf
  2. https://medlineplus.gov/druginfo/meds/a619032.html

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