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  3. Zapdol-Plus Tablet 10's

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Zapdol-Plus Tablet 10's, Pack of 10
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Written By Lakshmithulasi Yarragunta ,
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Zapdol-Plus Tablet 10's is used in the symptomatic treatment of moderate to severe pain. It works by blocking the release of certain chemical messengers in the brain that cause pain. Also, it blocks the transmission of pain signals to the brain to lower pain perception. It may cause nausea, vomiting, anxiety, stomach pain, indigestion, loss of appetite, dryness in the mouth, dizziness, dleepiness, and heartburn. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Composition :

ACECLOFENAC-100MG + PARACETAMOL-325MG + TRAMADOL-37.5MG

Manufacturer/Marketer :

Renocis Pharmaceuticals Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Zapdol-Plus Tablet 10's

Zapdol-Plus Tablet 10's belongs to the class of analgesics and is used in the symptomatic treatment of moderate to severe pain. Pain can be temporary (acute) or long-lasting (chronic) in nature. Acute pain is induced for a brief period of time by injury to muscle, bone, or other organ tissues. While chronic pain lasts for a long duration and is caused due to pathologies like nerve damage, osteoarthritis, etc.

Zapdol-Plus Tablet 10's contains Aceclofenac, Paracetamol, and Tramadol. Aceclofenac is a non-steroidal antiinflammatory drug (NSAID). Paracetamol is a common pain killer and has an antipyretic effect (reduces fever), whereas Tramadol is an opioid analgesic. Aceclofenac and Paracetamol both work by blocking the release of certain chemical messengers in the brain that cause pain. Tramadol is an opioid analgesic (a very strong pain reliever) that works by blocking the transmission of pain signals to the brain to lower pain perception.

Zapdol-Plus Tablet 10's can be taken with or after the meal. If stomach upset or irritation occurs, it is advisable to take Zapdol-Plus Tablet 10's with food or milk. It should be swallowed whole with a glass of water. People taking Zapdol-Plus Tablet 10's may experience Nausea, Vomiting, Anxiety, Stomach pain, Indigestion, Loss of appetite, Dryness in the mouth, Dizziness, Sleepiness, and Heartburn. However, all patients may not develop the same side effects. Inform your doctor if you notice any abnormal side effects. Stop taking this medicine and consult a doctor immediately if you experience symptoms like tightness of the chest, breathing difficulties, fever, skin rashes, increased heart rate, and or in case of any signs of hypersensitivity.

Before taking Zapdol-Plus Tablet 10's, inform your doctor if you have any known allergies to tramadol, paracetamol, or any other medications, foods, or herbal supplements. Ask the doctor if it is safe to use in children below 12 years, pregnant women, and breastfeeding mothers. It is advisable not to exceed the recommended dose or duration of treatment. Inform your doctor if you have liver or kidney disease, severe heart failure, and epilepsy.

Uses of Zapdol-Plus Tablet 10's

Treatment of Pain, Arthritis, etc.

Directions for Use

• Take Zapdol-Plus Tablet 10's with food to avoid stomach upset or as advised by a doctor.• Follow your doctor's instructions on the dosage and timing of this medication, to ensure the safety.• Swallow the medicine as a whole with glass of water.• Do not crush, break, or chew it.

Medicinal Benefits

Zapdol-Plus Tablet 10's plays a vital role in reducing pain and inflammation by blocking the release of chemical substances which cause pain and fever. Zapdol-Plus Tablet 10's relieves pain and inflammation in arthritic conditions with the benefit of increased antibiotic penetration and flow of blood at the injury site. Paracetamol can produce less gastric irritation compared to other painkillers like aspirin. So, it is well-tolerated in almost all age groups.$ name in combination has a faster onset of action and provides quick relief from the pain, and it is also prescribed for the conditions like fever and arthritis.

How Zapdol-Plus Tablet 10's Works

Zapdol-Plus Tablet 10's contains Aceclofenac, Paracetamol, and Tramadol. Aceclofenac is a non-steroidal antiinflammatory drug (NSAID). Paracetamol is a common pain killer and has an antipyretic effect (reduces fever), whereas Tramadol is an opioid analgesic. Aceclofenac and Paracetamol both work by blocking the release of certain chemical messengers in the brain that cause pain. Tramadol is an opioid analgesic (a very strong pain reliever) that works by blocking the transmission of pain signals to the brain to lower pain perception.

Storage

stored at room temperature below 30°C
Side effects of Zapdol-Plus Tablet
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.
  • Consume more fruits, vegetables, and cruciferous foods like cabbage, kale, and broccoli.
  • Reduced alcohol intake can enhance liver enzyme function.
  • Oxidative stress can be managed by eating foods rich in antioxidants, such as vitamins C and E.
  • Liver function tests regularly can help manage increased levels of AST.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
  • Include iron-rich foods like dark leafy vegetables, lean red meat, legumes and fish in your diet.
  • Consume vitamin C-rich foods as they aid iron absorption.
  • Limit tea, cocoa, and coffee as these can slow iron absorption.
  • Exercise regularly; however, do not overdo it.
  • Rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
  • Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
  • Protect your skin from extreme heat and try to apply wet compresses.
  • Soak in the cool bath, which gives a soothing impact to the affected area.

What if I have taken an overdose of Zapdol-Plus Tablet 10's

Do not take more than the prescribed dose of Zapdol-Plus Tablet 10's as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

Consumption of alcohol should be avoided during the treatment with Zapdol-Plus Tablet 10's as it may increase the risk of liver damage. Patients with stomach ulcers, gastric bleeding, severe heart failure, and liver or kidney disease should not take Zapdol-Plus Tablet 10's on their own. Besides this, it should be avoided during the last trimester of pregnancy unless there are compelling reasons for doing so. If you have a severe allergy to painkillers like asthma, rhinitis, angioedema (swelling under the skin), or skin rashes, immediately stop taking Zapdol-Plus Tablet 10's. Maintain caution when driving or operating machinery.

Drug-Drug Interactions

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TramadolSafinamide
Critical
TramadolTranylcypromine
Critical

Drug-Drug Interactions

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TramadolSafinamide
Critical
How does the drug interact with Zapdol-Plus Tablet:
Taking Safinamide with Zapdol-Plus Tablet can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Safinamide with Zapdol-Plus Tablet is not recommended as it can possibly result in an interaction, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination(seeing and hearing things that do not exist), fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and loose stools. Do not discontinue any medications without consulting your doctor.
TramadolTranylcypromine
Critical
How does the drug interact with Zapdol-Plus Tablet:
Combining Tranylcypromine with Zapdol-Plus Tablet can increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Tranylcypromine with Zapdol-Plus Tablet is not recommended, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination(seeing and hearing things that do not exist), fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting your doctor.
TramadolLinezolid
Critical
How does the drug interact with Zapdol-Plus Tablet:
Co-administration of Linezolid with Zapdol-Plus Tablet can increase the risk of serotonin syndrome and seizures.

How to manage the interaction:
Taking Linezolid with Zapdol-Plus Tablet is not recommended, consult a doctor before taking it. Consult a doctor if you experience confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea. Do not stop using any medications without talking to a doctor.
TramadolZiprasidone
Critical
How does the drug interact with Zapdol-Plus Tablet:
Co-administration of Ziprasidone with Zapdol-Plus Tablet can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Zapdol-Plus Tablet with Ziprasidone together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not discontinue any medications without consulting a doctor.
TramadolRasagiline
Critical
How does the drug interact with Zapdol-Plus Tablet:
Taking rasagiline with Zapdol-Plus Tablet can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Zapdol-Plus Tablet with Rasagiline is not recommended, as it can lead to an interaction, but can be taken if advised by your doctor. However, if you experience any symptoms like severe headache, blurred vision, confusion, seizures, chest pain, nausea or vomiting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, sweating, lightheadedness, and fainting, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
TramadolAlvimopan
Critical
How does the drug interact with Zapdol-Plus Tablet:
Co-administration of Zapdol-Plus Tablet with Alvimopan can make the side effects worse or more dangerous.

How to manage the interaction:
Taking Alvimopan with Zapdol-Plus Tablet is not recommended, please consult your doctor before taking it.
TramadolPhenelzine
Critical
How does the drug interact with Zapdol-Plus Tablet:
Combining Phenelzine with Zapdol-Plus Tablet can increase the risk of serotonin syndrome and seizures.

How to manage the interaction:
Taking Zapdol-Plus Tablet with Phenelzine is not recommended, please consult your doctor before taking it.
AceclofenacAtenolol
Severe
How does the drug interact with Zapdol-Plus Tablet:
Co-administration of Atenolol with Zapdol-Plus Tablet could increase the risk of low blood pressure.

How to manage the interaction:
Although there is a possible interaction between Atenolol and Zapdol-Plus Tablet, you can take these medicines together if prescribed by a doctor. Consult a doctor if you experience excessive sweating, shortness of breath, palpitations, or chest discomfort. Do not discontinue any medications without consulting a doctor.
ParacetamolLeflunomide
Severe
How does the drug interact with Zapdol-Plus Tablet:
Co-administration of Zapdol-Plus Tablet and Leflunomide may increase the risk of liver problems.

How to manage the interaction:
Although there is a possible interaction between Zapdol-Plus Tablet and Leflunomide, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
ParacetamolTeriflunomide
Severe
How does the drug interact with Zapdol-Plus Tablet:
Co-administration of Teriflunomide with Zapdol-Plus Tablet may increase the risk or severity of Liver problems.

How to manage the interaction:
Taking Zapdol-Plus Tablet with Teriflunomide together can possibly result in an interaction, but it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Do not go for heavy exercise as it may increase your joint pain in arthritis. Instead, you can do stretching and low-impact aerobic exercises like walking on a treadmill, bike riding, and swimming. You can also strengthen your muscle strength by lifting light weights.
  • In a chronic condition of arthritis or joint pain, try to include fish like salmon, trout, tuna, and sardines. These fishes are enriched with omega-3 fatty acids that have a minimum level of chemicals called cytokines, which ramp up inflammation.
  • Your sitting posture is important, especially when you have pain and inflammation condition. Try to sit as little as possible and only for a short time (10-15 min). Use back support like a rolled-up towel at the back of your curve to minimize pain. Keep your knees and hips at a right angle. Besides this, you can use a footrest if required.
  • Do not take alcohol. 
  • Take adequate rest whenever required.
  • Avoid driving or operating heavy machinery.

Habit Forming

Yes

Therapeutic Class

ANALGESICS

Zapdol-Plus Tablet 10's Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Unsafe

Taking excessive alcohol with Zapdol-Plus Tablet 10's can cause liver damage. So, it is advisable to avoid or limit intake of alcohol during the treatment with Zapdol-Plus Tablet 10's.

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Pregnancy

Caution

Zapdol-Plus Tablet 10's can have harmful effects on pregnancy. If you are pregnant, consult your doctor before taking this medicine. See medical advice if you become pregnant while on treatment with Zapdol-Plus Tablet 10's.

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Breast Feeding

Caution

If you are breastfeeding, you may experience some harmful effects of Zapdol-Plus Tablet 10's. In case you experience any of these, discontinue its use until you consult your doctor.

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Driving

Caution

Avoid driving or operating heavy machinery after taking Zapdol-Plus Tablet 10's as you may feel sleepy.

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Liver

Caution

The liver can be affected by Zapdol-Plus Tablet 10's. If you experience any unwanted effects of this drug, stop taking it and consult your doctor. You should restart Zapdol-Plus Tablet 10's only after medical advice.

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Kidney

Caution

Zapdol-Plus Tablet 10's rarely may affect kidneys. If you experience unwanted symptoms while using this medicine, seek medical advice.

bannner image

Children

Caution

Zapdol-Plus Tablet 10's should not be administered to children unless a child expert has prescribed it. The dose of the medication will be determined by your doctor based on your child's weight and the severity of the problem.

Have a query?

FAQs

Zapdol-Plus Tablet 10's is used in the symptomatic treatment of moderate to severe pain.

Your doctor decides the dose and duration of the medicine depending on your health condition. In general, it is not used for more than five days, as prolonged usage may lead to dependence.

Zapdol-Plus Tablet 10's, when taken by patients who are allergic to painkillers or NSAIDs, can be harmful. It should also be avoided in a person with a history of heart failure, kidney or liver disease, and stomach ulcers.

No. Zapdol-Plus Tablet 10's is not indicated for stomach pain. If you have stomach pain, refer to the doctor, as it may be a sign of stomach ulcer or gastric bleeding.

Country of origin

India

Manufacturer/Marketer address

B-58A, Path No. 8 Jamuna Nagar, Sodala Jaipur Jaipur Rj 302006 In
Other Info - ZAP0077

Disclaimer

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Author Details

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 18, 2025 | 6:44 AM IST

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Reference

  1. https://www.ndrugs.com/?s=aceclofenac/paracetamol/tramadol
  2. https://www.webmd.com/drugs/2/drug-21823/tramadol-acetaminophen-oral/details
  3. https://www.drugsupdate.com/generic/view/645

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