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Zaptra LS 12.5 Capsule 15's is used in the treatment of depression. It contains Clonazepam and Paroxetine, which increases levels of a calming chemical in the brain and also increases the serotonin hormone levels that improve mood, behaviour and prevent symptoms of depression. It may cause common side effects such as nausea, vomiting, diarrhoea, memory impairment, uncoordinated body movements, drowsiness, low sexual desire and delayed ejaculation. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Written By Lakshmithulasi Yarragunta , PharmD (PB)
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
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More about the Product

Manufacturer/Marketer :

Intas Pharmaceuticals Ltd

Consume Type :

Oral

Expires on or after :

Jan-28

Return Policy :

Not Returnable

About Zaptra LS 12.5 Capsule 15's

Zaptra LS 12.5 Capsule 15's is a prescription medicine used to treat generalized anxiety disorder, panic disorder, and anxiety associated with depression. It contains two medicines that work together to provide both rapid relief of anxiety symptoms and long-term improvement in mood and anxiety control.

For best results, take Zaptra LS 12.5 Capsule 15's exactly as prescribed and at the same time each day. It may be taken with or without food. Maintaining healthy sleep habits, regular physical activity, and stress-management techniques may help improve treatment outcomes.

Some people may experience mild side effects such as drowsiness, dry mouth, nausea, dizziness, or changes in appetite, especially during the first few weeks of treatment. These effects are often temporary and improve as the body adjusts to the medicine.

Seek immediate medical attention if you experience suicidal thoughts, thoughts of self-harm, severe mood changes, extreme confusion, difficulty breathing, or signs of a severe allergic reaction. Contact your doctor if side effects become persistent or troublesome.

Before starting treatment, inform your doctor if you have glaucoma, liver or kidney disease, breathing problems, sleep apnea, bipolar disorder, seizures, a history of substance misuse, or allergies to similar medicines. Avoid alcohol while taking Zaptra LS 12.5 Capsule 15's, and consult your doctor before use during pregnancy, breastfeeding, in older adults, or in children and adolescents.

Uses of Zaptra LS 12.5 Capsule 15's

Zaptra LS 12.5 Capsule 15's is used in the treatment of depression. The detailed uses of Zaptra LS 12.5 Capsule 15's are as follows:

  • Depression with Anxiety: Helps improve symptoms of depression while also reducing anxiety-related symptoms.
  • Generalized Anxiety Disorder: Helps reduce excessive worry, nervousness, irritability, and physical symptoms of anxiety.
  • Panic Disorder: Helps reduce the frequency and severity of panic attacks and the fear associated with them.

Key Benefits

Zaptra LS 12.5 Capsule 15's helps manage anxiety and related mood symptoms, supporting improved emotional well-being and daily functioning. By providing both short-term symptom relief and long-term emotional support, it helps individuals feel more comfortable and in control of their daily lives. Benefits may include:

  • Helps reduce anxiety, nervousness, and panic-related symptoms.
  • Provides early relief from anxiety symptoms while supporting long-term symptom control.
  • Helps improve mood and reduce persistent feelings of worry or emotional distress.
  • Supports emotional balance and overall mental well-being.
  • May promote better sleep by reducing anxiety-related sleep disturbances.
  • Improves daily functioning, social interactions, and overall quality of life.

Directions for Use

  • Take Zaptra LS 12.5 Capsule 15's with or without food or as advised by a doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication, to ensure the safety.
  • Swallow the medicine as a whole with glass of water.
  • Do not crush, break, or chew it.

How Zaptra LS 12.5 Capsule 15's Works

Zaptra LS 12.5 Capsule 15's contains Paroxetine and Clonazepam. • Paroxetine: It helps improve mood and emotional well-being by balancing certain chemicals in the brain. It helps reduce symptoms of anxiety, depression, excessive worry, and panic over time. • Clonazepam: It helps calm the brain and nervous system, reducing symptoms such as anxiety, panic, restlessness, nervousness, and muscle tension. It provides relatively quick relief from anxiety-related symptoms.
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Alcohol

Caution

Avoid consumption of alcohol while taking Zaptra LS 12.5 Capsule 15's as it may cause an increased sedative effect.

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Pregnancy

Unsafe

Zaptra LS 12.5 Capsule 15's may cause toxic effects to the fetus. So, it is not recommended for use in women who are pregnant or planning to become pregnant.

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Breast Feeding

Caution

Zaptra LS 12.5 Capsule 15's should be used with caution in breastfeeding mothers. Your doctor may advise you to stop breastfeeding while taking this medication.

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Driving

Caution

Do not drive or operate heavy machinery as Zaptra LS 12.5 Capsule 15's may cause drowsiness.

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Liver

Caution

Zaptra LS 12.5 Capsule 15's should be used with caution in patients with severe liver impairment. Dose adjustments may be required in such cases.

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Kidney

Caution

Zaptra LS 12.5 Capsule 15's should be used with caution in patients with kidney problems. Dose adjustments may be required in such cases. If you have any concerns regarding the use of Zaptra LS 12.5 Capsule 15's in patients with kidney problems, please consult a doctor.

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Children

Caution

Zaptra LS 12.5 Capsule 15's should not be used in children unless prescribed by a child specialist.

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Heart

Caution

Zaptra LS 12.5 Capsule 15's should be taken with extreme caution in patients with heart disease. Please consult your physician.

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Geriatrics

Caution

Zaptra LS 12.5 Capsule 15's can be given in elderly patients with extreme caution due to increased risk of adverse effects.

What if I have taken an overdose of Zaptra LS 12.5 Capsule 15's

If you take more than your prescribed dose, seek emergency medical attention immediately. Symptoms of an overdose may include severe drowsiness, confusion, slow reflexes, shallow breathing, or loss of consciousness.

Diet & Lifestyle Advise

  • Avoid alcohol and limit caffeine: Alcohol can cause dangerous drowsiness when combined with Zaptra LS 12.5 Capsule 15's, while caffeine can trigger panic attacks and worsen anxiety.
  • Eat high-fiber foods: Paroxetine can occasionally cause mild constipation. Eating fruits, vegetables, and whole grains while drinking plenty of water can keep your digestion smooth.
  • Maintain a consistent sleep routine: Go to bed and wake up at the same time daily to help support your brain's natural rhythms and maximize the calming effects of the medication.
  • Engage in low-impact exercise: Regular, gentle physical activities like walking, swimming, or stretching can help reduce stress and naturally boost your mood.
     
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How Soon It Starts Working

The time required for Zaptra LS 12.5 Capsule 15's to start to work: The time required for Zaptra LS 12.5 Capsule 15's to show its action is unknown. 

The time for which the effects of Zaptra LS 12.5 Capsule 15's last: The duration of action for Zaptra LS 12.5 Capsule 15's is unknown.

What if you forget to take Zaptra LS 12.5 Capsule 15's

If you miss a dose, take it as soon as you remember. However, if your next scheduled dose is only a few hours away, skip the missed dose and resume your regular schedule. Do not take two doses at the same time to make up for a missed one.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

  • Use caution during activities requiring alertness: Zaptra LS 12.5 Capsule 15's may cause significant drowsiness, dizziness, and slowed reflexes. Avoid driving, riding a bicycle, operating machinery, or performing hazardous tasks until you know how the medicine affects you.
  • Do not stop treatment abruptly: Never stop taking Zaptra LS 12.5 Capsule 15's suddenly, as this may cause withdrawal symptoms such as dizziness, anxiety, irritability, sleep disturbances, sweating, shaking, flu-like symptoms, or electric shock-like sensations. Your doctor will advise a gradual dose reduction when treatment needs to be stopped.
  • Use the medicine exactly as prescribed: Zaptra LS 12.5 Capsule 15's may cause physical dependence, especially when used for a long time. Do not increase the dose, use it more frequently than prescribed, or share it with anyone else.
  • Monitor for mood and behavior changes: Paroxetine carries a warning for an increased risk of suicidal thoughts and behavior in children, adolescents, and young adults, especially during the first few months of treatment or after dose changes. Close monitoring by family members, caregivers, and healthcare professionals is recommended during these periods.
  • Inform your doctor about all other medicines: Always tell your doctor or pharmacist about any prescription medicines, over-the-counter pain relievers, cough and cold products, or herbal supplements you are using, as many can interact with Zaptra LS 12.5 Capsule 15's.
  • Follow your treatment plan carefully: Zaptra LS 12.5 Capsule 15's is often used for short-term symptom relief. The duration of treatment will depend on your condition and response to therapy, as determined by your doctor.

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Drug-Drug Interactions

  • Monoamine oxidase inhibitors (MAOIs) (e.g., phenelzine, tranylcypromine): Taking these medicines alongside Zaptra LS 12.5 Capsule 15's can cause a life-threatening condition called serotonin syndrome. Do not use these medicines within 14 days of each other.
  • Pain relievers (e.g., aspirin, ibuprofen): Combining these with Zaptra LS 12.5 Capsule 15's may increase the risk of bruising, stomach bleeding, or internal bleeding.
  • Blood thinners (e.g., warfarin): Taking these medicines alongside Zaptra LS 12.5 Capsule 15's may increase the risk of serious bleeding and may require closer monitoring.
  • Selective Estrogen Receptor Modulators (hormone therapy )(e.g., Tamoxifen): Paroxetine may reduce the effectiveness of tamoxifen, a medicine used to treat breast cancer.
  • Sleeping pills, muscle relaxants, and opioid pain relievers: Taking these alongside Zaptra LS 12.5 Capsule 15's may cause excessive drowsiness, severe sedation, and dangerously slow breathing.

Drug-Food Interactions

Alcohol: Avoid consuming alcohol while taking Zaptra LS 12.5 Capsule 15's, as it can greatly increase drowsiness, dizziness, impaired coordination, and breathing problems.

Drug-Disease Interactions

  • Narrow-angle glaucoma: Zaptra LS 12.5 Capsule 15's may worsen symptoms in patients with narrow-angle glaucoma and should be used with caution.
  • Liver disease: Patients with liver impairment may process Zaptra LS 12.5 Capsule 15's more slowly, increasing the risk of side effects due to drug accumulation.
  • Kidney disease: Reduced kidney function may affect the removal of Zaptra LS 12.5 Capsule 15's from the body, increasing the likelihood of side effects.
  • Breathing disorders (e.g., asthma, sleep apnea, chronic lung disease): Zaptra LS 12.5 Capsule 15's may further suppress breathing and should be used with caution in patients with respiratory conditions.

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Habit Forming

Yes

Therapeutic Class

[ANTIDEPRESSANT]

FAQs

Zaptra LS 12.5 Capsule 15's is used in the treatment of depression.
Zaptra LS 12.5 Capsule 15's causes sleepiness, drowsiness, and dizziness. Do not drive or operate machinery if you experience these symptoms after taking Zaptra LS 12.5 Capsule 15's.
Zaptra LS 12.5 Capsule 15's causes weight gain due to increased appetite. Eat a healthy diet and exercise regularly to maintain a healthy weight.
Do not discontinue Zaptra LS 12.5 Capsule 15's without consulting your doctor as it could lead to recurring symptoms. To treat your condition effectually continue taking Zaptra LS 12.5 Capsule 15's for as long as prescribed. Moreover, stopping this medicine suddenly may result in withdrawal symptoms. Do not be reluctant to speak with your doctor if you feel any difficulty while taking Zaptra LS 12.5 Capsule 15's.
Zaptra LS 12.5 Capsule 15's may cause decreased sex-drive, problems with erection and orgasm. Consult your doctor if you have any concerns regarding this.
Dry mouth could be a side-effect of Zaptra LS 12.5 Capsule 15's. Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy might stimulate saliva and prevent drying of the mouth.
Some patients experienced increased suicidal thoughts or actions in the first few months of the treatment with Zaptra LS 12.5 Capsule 15's. Report to your doctor immediately if you notice any changes in your behaviour or mood while on this medication.
Yes, the use of Zaptra LS 12.5 Capsule 15's can cause sleepiness as a side effect. It's important to avoid driving or operating heavy machinery until you know how Zaptra LS 12.5 Capsule 15's affects you.
No, it's not safe to drink alcohol while taking Zaptra LS 12.5 Capsule 15's. Alcohol can increase the sedative effects of Zaptra LS 12.5 Capsule 15's, leading to increased drowsiness and dizziness. It's best to avoid alcohol to prevent these increased side effects.
Zaptra LS 12.5 Capsule 15's typically takes several weeks to show full effects, but it may differ from person to person. However, it’s important to complete the full course of treatment as prescribed by your doctor.
Store the Zaptra LS 12.5 Capsule 15's at room temperature protected from light and moisture. Keep it out of reach of children.
The common side effects of Zaptra LS 12.5 Capsule 15's are nausea, vomiting, diarrhoea, memory impairment, uncoordinated body movements, drowsiness, low sexual desire and delayed ejaculation. If any of these side effects persist or worsen, please consult doctor.

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Country of origin

India

Manufacturer/Marketer address

Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.
Other Info - ZAP0076
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