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Zeftabac Injection is an antibiotic used in treating bacterial infections. This medicine stops the growth of bacteria and thereby helps reduce various bacterial infections of the urinary tract, respiratory tract and abdomen. This medicine is not effective for treating viral infections. Common side effects include diarrhoea, nausea & vomiting. This medicine is not effective for the treatment of viral infections.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Manufacturer/Marketer :

Lupin Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Zeftabac Injection

Zeftabac Injection is a prescription antibiotic injection used to treat severe bacterial infections caused by certain bacteria, including some that are resistant to many commonly used antibiotics. It is commonly prescribed for complicated infections of the urinary tract, abdomen, and lungs. This medicine helps clear the infection by stopping the growth of harmful bacteria.

Because this antibiotic is often reserved for difficult-to-treat or multidrug-resistant (MDR) bacterial infections, it should only be used when prescribed by a healthcare professional. Using antibiotics only when needed helps reduce antibiotic resistance and keeps them effective for future infections.

This medicine is injected directly into a vein, usually on a regular schedule determined by your doctor to maintain a constant level of the drug in your body. Because it is given as an injection, food does not affect how it works. Drinking plenty of fluids, eating a balanced diet, and getting adequate rest can support your body's recovery during treatment.

While using Zeftabac Injection, you may experience mild side effects such as nausea, diarrhea, headache, or redness at the injection site. However, contact your doctor immediately if you develop severe watery or bloody diarrhea, skin rashes, swelling of the face or throat, difficulty breathing, seizures, or yellowing of the skin or eyes.

If you have a severe infection, it is normal to feel tired or worried about your recovery. Taking your medicine exactly as prescribed and keeping in touch with your healthcare team can help ensure the best possible outcome.

Talk to your doctor before starting this medicine if you have kidney problems, a history of seizures, liver disease, or allergies to cephalosporin, penicillin, or other beta-lactam antibiotics. Tell your doctor about all medicines you take, especially water pills (diuretics) or other medicines that may affect kidney function. Inform your healthcare provider if you are pregnant, breastfeeding, caring for a child receiving this medicine, or if the patient is elderly, as closer monitoring may be needed.

Uses of Zeftabac Injection

Zeftabac Injection is used in the treatment of Bacterial infections. The detailed uses of Zeftabac Injection are as follows:

  • Complicated urinary tract infections: Zeftabac Injection helps clear deep-seated bacterial infections in the bladder and kidneys, reducing pain and fever.
  • Complicated intra-abdominal infections: This medicine works with other treatments to clear serious bacterial infections inside the stomach and abdomen.
  • Hospital-acquired pneumonia: Zeftabac Injection treats severe lung infections acquired during a hospital stay, helping to restore normal breathing and lung function.

Key Benefits

Zeftabac Injection provides reliable treatment for severe bacterial infections, including many infections caused by bacteria that have become resistant to commonly used antibiotics. By delivering the antibiotic directly into the bloodstream, it quickly reaches the site of infection, helping control bacterial growth, reduce complications, and support recovery when used exactly as prescribed.

  • Treats severe bacterial infections: Helps control serious bacterial infections that may not respond to standard antibiotics.
  • Works quickly: Delivers the antibiotic directly into the bloodstream, allowing it to reach the infection site rapidly.
  • Prevents the spread of infection: Helps stop bacteria from spreading to other parts of the body, reducing the risk of complications.
  • Overcomes bacterial resistance: Avibactam blocks certain bacterial enzymes (beta-lactamases) that can break down ceftazidime, helping the antibiotic remain effective against many resistant bacteria.
  • Supports faster recovery: By effectively controlling the infection, it helps relieve symptoms and promotes recovery when used as prescribed.

Directions for Use

  • Follow your doctor's instructions regarding dosage and timing of Zeftabac Injection.
  • Zeftabac Injection will be administered by a healthcare professional.
  • Do not self-administer.

How Zeftabac Injection Works

Zeftabac Injection contains two active ingredients. Ceftazidime is a cephalosporin antibiotic that kills bacteria by blocking the formation of their protective outer cell wall. Without this wall, the bacteria become weak and eventually die. Avibactam is a beta-lactamase inhibitor. Some bacteria produce enzymes called beta-lactamases that can destroy antibiotics before they work. Avibactam blocks many of these enzymes, protecting ceftazidime from being broken down and allowing it to remain effective against many resistant bacteria.
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Alcohol

Caution

The interaction of Zeftabac Injection with alcohol is unknown. Please consult a doctor before consuming alcohol while using Zeftabac Injection.

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Pregnancy

Caution

Please consult a doctor if you are pregnant or planning for pregnancy. Your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Zeftabac Injection may be excreted in human milk in small amounts. Therefore, it is given to breastfeeding mothers only if the doctor thinks benefits are greater than risks. Please consult a doctor if you are breastfeeding.

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Driving

Caution

Zeftabac Injection may cause dizziness. Therefore, avoid driving if you feel dizzy after taking Zeftabac Injection.

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Liver

Caution

Take Zeftabac Injection with caution, especially if you have a history of liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Zeftabac Injection with caution, especially if you have a history of kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Caution

Zeftabac Injection should be used in children only in doses as prescribed by a doctor. Zeftabac Injection is not recommended for use in children below 3months.

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Heart

Caution

Zeftabac Injection should be administered with caution in patients with heart problems. Please inform your doctor if you have any pre-existing heart problems before receiving Zeftabac Injection.

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Geriatrics

Caution

Zeftabac Injection should be administered with caution in elderly patients due to an increased risk of side effects. Seek medical advice if you have any concerns.

What if I have taken an overdose of Zeftabac Injection

An overdose is rare when the medicine is given by a professional. However, if you suspect an overdose or experience severe side effects like muscle twitching or seizures, seek immediate medical attention or contact a poison control center right away.

Diet & Lifestyle Advise

  • Stay well-hydrated: Drink plenty of water to help your kidneys process the medication and flush out toxins.
  • Support your gut health: Antibiotics can temporarily disrupt your gut bacteria. Consider eating fermented foods like yogurt or taking a probiotic supplement after completing your course, but talk to your doctor first.
  • Get plenty of rest: Allow your body to direct its energy toward fighting the infection by getting adequate sleep.
  • Eat easy-to-digest foods: If you experience nausea or mild stomach upset, stick to plain foods like rice, toast, or clear broths.
  • Practice good hand hygiene and complete the full course of antibiotics to help prevent the spread of infection and reduce antibiotic resistance.
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How Soon It Starts Working

The time required for Zeftabac Injection to start to work: Zeftabac Injection ideally shows its action within 1 hour of administration. The time for which the effects of Zeftabac Injection last: Zeftabac Injection effect lasts for 6 to 8 hours.

What if you forget to take Zeftabac Injection

Since this medicine is usually injected by a healthcare provider in a clinical setting, a missed dose is unlikely. If you are managing your infusions at home and miss a dose, contact your doctor or nurse immediately for guidance. Do not inject a double dose to make up for a missed one.

Storage

• Store the dry powder vials of Zeftabac Injection at controlled room temperature, between 20°C to 25°C (68°F to 77°F).

Drug Warnings

  • Always check the injection solution for discoloration or visible particles before use. Do not use it if it appears cloudy or contains particles.
  • Complete the full prescribed course, even if you feel better, unless your doctor tells you to stop.
  • This antibiotic is usually reserved for serious infections caused by resistant bacteria. Do not use it for viral illnesses such as colds or flu.
  • Inform your healthcare provider if you have ever had an allergic reaction to ceftazidime, avibactam, cephalosporins, penicillins, or other beta-lactam antibiotics.
  • Your doctor may perform blood tests during treatment to monitor kidney function and, during prolonged therapy, liver function and blood cell counts.
  • Seek medical attention immediately if you develop severe diarrhea during treatment or even several weeks after completing the antibiotic, as this may be caused by Clostridioides difficile (C. difficile) infection.
  • Do not use Zeftabac Injection if you have had a severe allergic reaction (such as anaphylaxis) to ceftazidime, avibactam, or any other cephalosporin antibiotic or you have experienced a serious allergic reaction to other beta-lactam antibiotics, such as penicillins or carbapenems, unless your doctor determines that the benefits outweigh the risks.

Drug-Drug Interactions

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  • Chloramphenicol: Taking this antibiotic alongside Zeftabac Injection may reduce the overall effectiveness of your treatment.
  • Strong water pills (diuretics like furosemide): Combining these medications with Zeftabac Injection can increase the risk of kidney strain.
No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

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  • No clinically significant food interactions are known with Zeftabac Injection when used as directed.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTIBIOTICS]

FAQs

Zeftabac Injection belongs to a class of medicines called antibiotics used in the treatment of bacterial infections of the urinary tract, respiratory tract and abdomen.
Zeftabac Injection works by damaging the bacterial cell wall (protective covering) that is necessary for their survival and by increasing bacterial sensitivity.
Exercise caution while taking Zeftabac Injection with diuretics/water tablets. You are not advised to take Zeftabac Injection with a diuretic called furosemide as co-administration of these two medicines may increase the risk of kidney problems, especially in patients with kidney impairment and also when Zeftabac Injection is given in high doses. However, please consult your doctor before taking Zeftabac Injection with other medicines.
Before receiving Zeftabac Injection, you must inform your doctor if you are allergic to foods or medicines. You should also inform your doctor if you have kidney problems or diabetes or if you are pregnant or breastfeeding. If you are on a controlled sodium diet, let your doctor know before starting the medication. Also, inform your doctor if you are receiving or scheduled to receive any vaccinations.
The common side effects of Zeftabac Injection include nausea, diarrhoea, and redness and swelling at the site of injection. These side effects are usually temporary, and not everyone will experience them. In most cases, they resolve on their own without the need for medical treatment. However, if the side effects persist or worsen, please consult your doctor for further advice and management.
If a bacterial infection is not treated, the bacteria can continue to grow and spread throughout the body. This may lead to serious health complications, such as damage to vital organs or tissues. In severe cases, it can result in sepsis (a life-threatening, body-wide infection). Additionally, the infection may become harder to treat over time, as the bacteria can develop resistance to antibiotics. It is important to seek medical treatment to prevent these risks and help your body recover.
Zeftabac Injection is given as an injection directly into a vein (intravenous infusion) by a doctor or nurse, usually in a hospital or clinic setting. Talk to your doctor if you have questions about your administration schedule.
In some cases, you may be allowed to inject this medicine at home after receiving proper training from a healthcare professional. Always follow the exact instructions provided by your medical team and talk to your doctor if you face any difficulties.
Mild diarrhea can happen during antibiotic treatment, but if you experience severe, watery, or bloody diarrhea with stomach cramps, contact your healthcare provider immediately as this could be a sign of a serious gut infection. Talk to your doctor before taking any over-the-counter anti-diarrheal medicines.
There is limited information about the use of Zeftabac Injection during pregnancy. Your doctor will prescribe it only if the expected benefit outweighs any possible risk to the baby. Small amounts of ceftazidime may pass into breast milk, so breastfeeding mothers should discuss the benefits and potential risks with their doctor before treatment.
There is no known direct interaction between alcohol and Zeftabac Injection. However, alcohol may worsen side effects such as dizziness, nausea, or dehydration and may slow your recovery from a serious infection. It is generally best to avoid or limit alcohol until you have recovered. Talk to your doctor if you have questions.
If you are receiving this medicine in a hospital, your medical team will manage your doses. If you are taking it at home and miss a dose, contact your healthcare provider immediately to schedule your next dose. Talk to your doctor or pharmacist if you have questions.
No, Zeftabac Injection is an antibiotic and only works against infections caused by bacteria. It will not work against viral infections like the common cold, flu, or COVID-19. Talk to your doctor to ensure you receive the correct diagnosis.
This medicine starts fighting bacteria as soon as it enters your bloodstream. However, you may not notice an improvement in your symptoms for a couple of days. Always finish the full course of treatment as prescribed. Talk to your doctor if you do not feel better after a few days.
Yes. This medicine may be prescribed for children when appropriate. However, the dose is carefully calculated based on the child's age, body weight, kidney function, and the type of infection. It should only be given under the supervision of a healthcare professional. Talk to your child's doctor if you have any questions.

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Country of origin

India

Manufacturer/Marketer address

Lupin Ltd, 3Rd Floor Kalpataru Inspire, Off. W E Highway, Santacruz (East), Mumbai 400 055. India.
Other Info - ZEF0088
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