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Zenporate Cr 300Mg Tablet is used to treat seizures and manage manic episodes in bipolar disorder. It also helps prevent migraine attacks. It supports better brain stability and reduces symptom frequency. This helps improve daily functioning and overall quality of life.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

VALPROIC ACID-300MG

Manufacturer/Marketer :

Elder Pharmaceuticals Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

NPPA :

Regulated

About Zenporate Cr 300Mg Tablet

Zenporate Cr 300Mg Tablet is an oral prescription medication used to control various types of seizures in people with epilepsy. It is also prescribed to treat the manic phase of bipolar disorder and to prevent migraine headaches from occurring. This medicine works by calming overactive nerve activity in the brain to help stabilise your mood and prevent abnormal brain signals.

To get the best results, you must take Zenporate Cr 300Mg Tablet consistently every day at the same time as directed by your doctor. You can take this medicine with or without food, but taking it with meals can help prevent an upset stomach. Incorporating a regular sleep schedule, managing stress levels, and avoiding known seizure or migraine triggers can also support the effectiveness of your treatment.

While taking Zenporate Cr 300Mg Tablet , you may experience some common side effects such as mild sleepiness, nausea, or temporary hair thinning. However, you must seek medical help immediately if you notice serious symptoms like severe abdominal pain, dark urine, yellowing of your skin or eyes, or unusual mood changes.

Before starting this medication, tell your doctor if you have a history of liver problems, kidney disease, or pancreatic disorders. Do not take this if you have a family history of severe liver damage or genetic mitochondrial disorders. Pregnant women, or those planning to become pregnant, should not take this medicine for migraine prevention, and should only use it for epilepsy or bipolar disorder if no other treatments are suitable, due to a high risk of birth defects.

Zenporate Cr 300Mg Tablet can interact with alcohol, which can worsen drowsiness, and with other medicines like aspirin or certain antidepressants by changing how your body processes them. If you are pregnant, breastfeeding, or an older adult, consult your doctor or pharmacist to discuss the risks and benefits before starting this medicine.

Uses of Zenporate Cr 300Mg Tablet

Zenporate Cr 300Mg Tablet is used for the treatment of epilepsy (seizures), bipolar disorder, and migraine. The detailed uses of Zenporate Cr 300Mg Tablet are as follows:

  • Epilepsy and Seizure Control: Zenporate Cr 300Mg Tablet helps prevent and control various types of seizures, including absence seizures, complex partial seizures, and generalised tonic-clonic seizures, by reducing abnormal electrical activity in the brain.
  • Bipolar Disorder (Manic Episodes): Zenporate Cr 300Mg Tablet helps stabilise mood swings and manage manic episodes, which are periods of overly high, excited, or irritable mood.
  • Migraine Prevention: Zenporate Cr 300Mg Tablet reduces the frequency and severity of migraine headaches when taken daily as a preventive treatment.

Key Benefits

Zenporate Cr 300Mg Tablet helps manage seizures, stabilise mood in bipolar disorder, and prevent migraine headaches, helping you lead a more active and balanced life.

The following are the benefits of Zenporate Cr 300Mg Tablet :

  • Helps reduce the frequency and severity of seizures.
  • Improves mood stability in people with bipolar disorder.
  • Reduces the occurrence of migraine headaches.
  • Supports better concentration and emotional well-being.
  • Promotes greater confidence in carrying out everyday activities.
  • Provides long-term control of symptoms with regular treatment.
Side effects of Zenporate Cr 300Mg Tablet
Here are the steps to manage medication-triggered tremors or involuntary shaking:
  • Notify your doctor immediately if you experience tremors or involuntary shaking after taking medication or adjusting your medication regimen.
  • Your doctor may adjust your medication regimen or recommend alternative techniques like relaxation, meditation, or journaling to alleviate tremor symptoms.
  • Your doctor may direct you to practice stress-reducing techniques, such as deep breathing exercises, yoga, or journaling.
  • Regular physical activity, such as walking or jogging, can help reduce anxiety and alleviate tremor symptoms.
  • Your doctor may recommend lifestyle changes, such as avoiding caffeine, getting enough sleep, and staying hydrated, to help manage tremors.
  • Maintain regular follow-up appointments with your doctor to monitor tremor symptoms and adjust treatment plans as needed.
  • Managing a low platelet count (thrombocytopenia) caused by medication usage requires a multi-step approach. Here are some steps to help manage the condition:
  • Inform your doctor about your low platelet count and medication usage. They will assess the situation and guide the best course of action.
  • Your doctor may recommend adjusting or stopping the medication that is causing a low platelet count. This could involve switching to alternative medication or reducing the dosage.
  • Monitor your platelet count regularly through blood tests to track any changes. This will help the doctor determine the effectiveness of the treatment plan.
  • If an underlying condition, such as infection or inflammation, contributes to the low platelet count, your doctor will treat it.
  • In some cases, alternative treatments like platelet transfusions or medications that stimulate platelet production may be necessary.
  • Avoid risky activities and certain medications; eat a balanced diet with plenty of water to reduce bleeding risk and boost overall health.
  • If you experience severe bleeding or bruising, seek emergency medical attention immediately.
  • Include iron-rich foods like dark leafy vegetables, lean red meat, legumes and fish in your diet.
  • Consume vitamin C-rich foods as they aid iron absorption.
  • Limit tea, cocoa, and coffee as these can slow iron absorption.
  • Exercise regularly; however, do not overdo it.
  • Consume controlled amounts of salt to raise sodium levels.
  • Eat fresh fruits like apples, berries, oranges, mangoes, and bananas.
  • Include fresh vegetables like broccoli, sweet potatoes, beets, okra, spinach, peppers, carrots, and edamame.
  • Choose frozen vegetables without added butter or sauce.
  • Drink electrolyte beverages like sports drinks or electrolyte solutions to replenish sodium and other electrolytes.
  • Avoid excessive salt intake, but allow for controlled increases as needed.
  • Monitor and manage underlying health conditions that may contribute to hyponatremia.
  • Polycystic ovary syndrome is a commonly occurring health condition that needs to be corrected.
  • Maintain a diet rich in omega fatty acids like fish, nuts and plant oils.
  • Exercise to maintain a healthy weight within BMI to improve your condition.
  • Make sure to get sufficient sleep and avoid stress, which could increase the side effects of PCOD.
  • Smoking and drinking alcohol can worsen PCOD; therefore, avoid them.
  • Confusion is a major psychotic disorder that needs immediate medical attention.
  • Acknowledge your experience and put effort to control confusion.
  • Avoid smoking and alcohol intake as it can worsen the condition and increase your confusion.
  • Practice meditation and yoga to avoid anxiety, which can be one of the leading causes.
  • Talk to your dietician and consume food that can improve your mental health.
  • Hallucination is a major psychotic disorder that needs immediate medical attention.
  • Acknowledge your experience and put effort to control hallucinations. You can share what is being seen with a therapist to know whether they are real or imaginary.
  • Avoid smoking and alcohol intake as it can worsen the condition and increase your imagination.
  • Practice meditation and yoga to avoid anxiety, which can be one of the leading causes of hallucinations.
  • Talk to your dietician and consume food that can improve your mental health.

Directions for Use

  • Swallow the tablets or capsules whole with a full glass of water. Do not crush, chew, or break it.
  • Take this medicine with food if it causes an upset stomach.
  • Never change your dose or stop taking this medication suddenly without talking to your doctor first. Stopping abruptly can cause your seizures to return or worsen.
  • Always follow your doctor's exact instructions regarding your dosing schedule.

How Zenporate Cr 300Mg Tablet Works

Zenporate Cr 300Mg Tablet contains valproic acid, which works by stabilising electrical activity in the brain. In conditions like epilepsy, bipolar disorder, and migraines, brain cells can become overactive and send rapid, uncontrolled signals. To help restore balance, Zenporate Cr 300Mg Tablet increases the levels of a natural calming chemical in the brain called gamma-aminobutyric acid (GABA), which helps slow excessive nerve activity. It also reduces abnormal electrical signalling by blocking certain sodium channels and T-type calcium channels in nerve cells. Together, these actions help keep nerve signals stable, thereby preventing seizures, managing mood shifts, and reducing processes that can trigger migraines.
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Alcohol

Unsafe

Do not consume alcohol while taking Zenporate Cr 300Mg Tablet as alcohol can worsen the side effects of the Zenporate Cr 300Mg Tablet , including sleepiness and dizziness.

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Pregnancy

Unsafe

Zenporate Cr 300Mg Tablet is a Category D pregnancy drug. It is not recommended for use during pregnancy as it may cause an increase in the risk of a cleft lip, which is a congenital disability in the unborn baby. If you are a female able to have a baby, you must use an effective method of birth control (contraception) without interruption during your entire treatment with Zenporate Cr 300Mg Tablet .

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Breast Feeding

Caution

Zenporate Cr 300Mg Tablet passes into breast milk and may harm your infant. Please consult a doctor if you are breastfeeding before taking Zenporate Cr 300Mg Tablet . Breastfed infants are at risk for valproic acid-induced hepatotoxicity, so infants should be monitored for jaundice and other signs of liver damage during maternal therapy.

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Driving

Unsafe

Zenporate Cr 300Mg Tablet may cause dizziness, drowsiness, or fatigue in some individuals. Therefore, avoid driving if you feel drowsy, dizzy or tired after taking Zenporate Cr 300Mg Tablet .

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Liver

Caution

Inform your doctor before taking the Zenporate Cr 300Mg Tablet if you have a history of liver diseases. Extreme caution is recommended in patients with impaired liver function. Your doctor will weigh the benefits and potential risks before prescribing Zenporate Cr 300Mg Tablet .

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please inform your doctor if you have kidney impairment.

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Children

Caution

Use is not recommended for children under 10 years old. Your doctor will decide the dose based on your child's condition if they are more than ten years old.

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Heart

Caution

Zenporate Cr 300Mg Tablet can be used cautiously in patients with heart disease if prescribed by a physician.

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Geriatrics

Caution

Zenporate Cr 300Mg Tablet can be given to elderly patients with extreme caution if prescribed by a physician.

What if I have taken an overdose of Zenporate Cr 300Mg Tablet

If you suspect an overdose, seek immediate emergency medical attention or call your local poison control centre. Symptoms of an overdose may include severe drowsiness, shallow breathing, or loss of consciousness.

Diet & Lifestyle Advise

  • Avoid alcohol: Do not drink alcohol while taking this medicine, as it can increase drowsiness, dizziness, and the risk of liver problems.
  • Maintain a healthy diet: Eat a balanced diet and check your weight regularly, as this medicine may increase your appetite and lead to weight gain.
  • Stay well hydrated: Drink plenty of water throughout the day to support kidney function and your overall health.
  • Care for your hair and skin: Use gentle hair care products and moisturising skin creams if you notice temporary hair thinning or dry skin while taking this medicine.
  • Keep a symptom diary: Record your seizures, mood changes, or migraine episodes to help your doctor monitor your progress and adjust your treatment if needed.
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Have a query?

How Soon It Starts Working

  • The time required for Zenporate Cr 300Mg Tablet to start to work: Zenporate Cr 300Mg Tablet ideally shows its action within 1 to 4 hours after administration.
  • The time for which the effects of Zenporate Cr 300Mg Tablet last: The effect of Zenporate Cr 300Mg Tablet lasts for 13 to 19 hours.

What if you forget to take Zenporate Cr 300Mg Tablet

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.

Storage

• Store in a cool and dry place away from sunlight.• Keep Zenporate Cr 300Mg Tablet out of the sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

  • Attend regular blood tests: Get the blood tests your doctor recommends to check your liver, pancreas, and the amount of medicine in your body. This helps ensure the medicine is working safely.
  • Use effective birth control: If you can become pregnant, use reliable birth control while taking this medicine. Zenporate Cr 300Mg Tablet can seriously harm an unborn baby.
  • Watch for mood changes: Contact your doctor right away if you notice unusual changes in your mood, behaviour, or thoughts, including feelings of depression or thoughts of self-harm.
  • Tell healthcare providers about this medicine: Inform your doctor, dentist, or surgeon that you are taking this medicine before any procedure. It can affect how your blood clots.
  • Be careful with activities requiring alertness: Do not drive, operate heavy machinery, or do other dangerous activities until you know how this medicine affects you. It may cause drowsiness or reduce alertness.

Drug-Drug Interactions

verifiedApollotooltip
  • Anti-seizure medicines (e.g., phenytoin, carbamazepine): Taking these medicines alongside Zenporate Cr 300Mg Tablet may affect how either medicine works and may increase the risk of side effects or reduce seizure control.
  • Blood thinners (e.g., warfarin): Taking these medicines with Zenporate Cr 300Mg Tablet may increase the risk of bleeding and may require closer monitoring.
  • Certain antibiotics (e.g., meropenem, imipenem): These antibiotics may greatly reduce the amount of Zenporate Cr 300Mg Tablet in the body, increasing the risk of breakthrough seizures.
Sodium ValproateSodium phenylbutyrate
Critical

Drug-Drug Interactions

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Sodium ValproateSodium phenylbutyrate
Critical
How does the drug interact with Zenporate Cr 300Mg Tablet:
Combining Sodium phenylbutyrate and Zenporate Cr 300Mg Tablet can increase ammonia levels in the blood.

How to manage the interaction:
Taking Sodium phenylbutyrate with Zenporate Cr 300Mg Tablet is not recommended, but it can be taken if prescribed by a doctor. If you experience any symptoms like sudden dizziness, lightheadedness, fainting, headache, shortness of breath, nausea, vomiting, chest pain or tightness, rapid heartbeat, or memory loss, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Zenporate Cr 300Mg Tablet:
Co-administration of Meropenam and Zenporate Cr 300Mg Tablet together can reduce the effect of Zenporate Cr 300Mg Tablet.

How to manage the interaction:
Co-administration of Meropenam and Zenporate Cr 300Mg Tablet can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any unusual symptoms, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Zenporate Cr 300Mg Tablet:
Co-administration of Lithium with Zenporate Cr 300Mg Tablet can increase the risk irregular heart rhythm.

How to manage the interaction:
Co-administration of Lithium and Zenporate Cr 300Mg Tablet can lead to an interaction, but it can be taken if advised by your doctor. However, consult your doctor immediately if you experience any symptoms like dizziness, drowsiness, confusion, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, and difficulty concentrating. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Zenporate Cr 300Mg Tablet:
Co-administration of Teriflunomide and Zenporate Cr 300Mg Tablet can increase the risk of causing liver problems.

How to manage the interaction:
Co-administration of Teriflunomide and Zenporate Cr 300Mg Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark-colored urine, light-colored stools, and yellowing of the skin or eyes. Avoid alcohol while taking these medications, and consult your doctor immediately. Do not discontinue any medications without consulting your doctor.
How does the drug interact with Zenporate Cr 300Mg Tablet:
Co-administration of Ketamine and Zenporate Cr 300Mg Tablet can increase side effects and cause respiratory depression.

How to manage the interaction:
Co-administration of Ketamine and Zenporate Cr 300Mg Tablet can lead to an interaction, but it can be taken if your doctor advises. However, consult your doctor immediately if you experience any symptoms like dizziness, drowsiness, confusion, difficulty concentrating, excessive sedation, impaired thinking, judgment, and motor coordination. Avoid driving or operating hazardous machinery until you know how these medications affect you. Do not discontinue any medications without consulting the doctor.
How does the drug interact with Zenporate Cr 300Mg Tablet:
Co-administration of Leflunomide and Zenporate Cr 300Mg Tablet can increase the risk of causing liver problems.

How to manage the interaction:
Co-administration of Leflunomide and Zenporate Cr 300Mg Tablet can lead to an interaction, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Severe
How does the drug interact with Zenporate Cr 300Mg Tablet:
Co-administration of Vorinostat with Zenporate Cr 300Mg Tablet can increase the risk of unusual bleeding.

How to manage the interaction:
Co-administration of Vorinostat and Zenporate Cr 300Mg Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, consult your doctor immediately. Do not discontinue any medications without consulting your doctor.
How does the drug interact with Zenporate Cr 300Mg Tablet:
Using buprenorphine together with Zenporate Cr 300Mg Tablet may increase the risk of severe side effects, including respiratory problems and loss of consciousness.

How to manage the interaction:
Although the administration of buprenorphine alongside Zenporate Cr 300Mg Tablet can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Zenporate Cr 300Mg Tablet:
Co-administration of Zenporate Cr 300Mg Tablet with doripenem can reduce the blood levels of valproic acid.

How to manage the interaction:
Co-administration of Doripenam and Zenporate Cr 300Mg Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, involuntary muscle movements, or memory loss, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Zenporate Cr 300Mg Tablet:
The combined use of Ertapenem and Zenporate Cr 300Mg Tablet can reduce the blood levels of valproic acid.

How to manage the interaction:
Co-administration of Ertapenem and Zenporate Cr 300Mg Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like loss of seizure control or changes in behavior, consult your doctor immediately. Do not discontinue any medications without consulting the doctor.

Drug-Food Interactions

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  • Carbonated beverages (e.g., soda, sparkling water): Consuming these drinks while taking Zenporate Cr 300Mg Tablet may increase the risk of irritation to the mouth and throat.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[ANTICONVULSANT]

FAQs

Zenporate Cr 300Mg Tablet is used to treat epilepsy/seizures/fits. In addition, it also helps treat manic episodes associated with bipolar disorder and prevent migraine symptoms (like a headache).
Zenporate Cr 300Mg Tablet decreases the excessive and abnormal nerve activity in the brain. Thereby helping in controlling seizures.
Zenporate Cr 300Mg Tablet helps to treat manic episodes associated with bipolar disorder by increasing the amount of a chemical substance called GABA; this helps block nerve transmission across the brain and provides a calming effect.
Zenporate Cr 300Mg Tablet limits the transmission of nerve pain, thereby preventing migraine headaches. Migraines are a neurological condition characterised by intense headaches.
Zenporate Cr 300Mg Tablet may cause weight gain due to an increase in appetite. Maintain a healthy weight by following a healthy diet and exercising regularly.
Use an effective method of contraception during the treatment with Zenporate Cr 300Mg Tablet . Avoid getting pregnant while taking Zenporate Cr 300Mg Tablet as it could lead to serious birth defects. Do not stop taking Zenporate Cr 300Mg Tablet and consult your doctor immediately if you become pregnant.
Zenporate Cr 300Mg Tablet may cause weight gain due to an increase in appetite. Maintain a healthy weight by following a healthy diet and exercising regularly.
Zenporate Cr 300Mg Tablet may cause common side effects such as nausea, vomiting, headache, sleepiness, tremor, weakness, dizziness, stomach pain, and weight gain. If these side effects persist or worsen, please consult your doctor.
Zenporate Cr 300Mg Tablet contains Valproic acid as its active ingredient.
Take Zenporate Cr 300Mg Tablet with food to avoid stomach upset or as advised by your doctor.
You are recommended to avoid alcohol consumption while taking Zenporate Cr 300Mg Tablet as it may worsen the side effects of the Zenporate Cr 300Mg Tablet , including sleepiness and dizziness.
No, Zenporate Cr 300Mg Tablet does not cause addiction. However, Zenporate Cr 300Mg Tablet should be used as per the dose and duration prescribed by your doctor. Do not self-medicate.
Zenporate Cr 300Mg Tablet does not cure epilepsy; it only helps prevent seizures. However, you must take Zenporate Cr 300Mg Tablet for as long as your doctor advises. If you face any difficulty while taking Zenporate Cr 300Mg Tablet , consult your doctor.
If you stop taking Zenporate Cr 300Mg Tablet suddenly, it may increase the risk of recurrence of seizures. Therefore, it should be stopped gradually. If you feel the need to discontinue Zenporate Cr 300Mg Tablet , please consult your physician.
Some birth control pills (oestrogen-containing birth control pills) may lower the levels of Zenporate Cr 300Mg Tablet in blood. Thus, inform your doctor if you are using birth control pills and discuss with your doctor about a suitable method of contraception.
Zenporate Cr 300Mg Tablet is safe for long-term use in many patients when prescribed by a physician. In rare cases, prolonged use of Zenporate Cr 300Mg Tablet may weaken bones, thereby increasing the risk of fractures (osteopenia and osteoporosis). Get regular checkups for bone health if you have been taking Zenporate Cr 300Mg Tablet for a long time.
Zenporate Cr 300Mg Tablet may cause hair thinning, hair colour changes and even hair loss. If you have any concerns about this, please ask your doctor whether it is possible to reduce the dose of Zenporate Cr 300Mg Tablet . Your hair may regrow after either lowering your dose or changing medication.
Your doctor will order regular blood tests to check the levels of Zenporate Cr 300Mg Tablet in your body and to monitor how well your liver and blood cells are working. This ensures the medicine is working safely and effectively. Talk to your doctor if you have questions about your tests.

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Country of origin

India

Manufacturer/Marketer address

“Elder House” Plot No. C-9, Dalia Industrial Estate, Off Veera Desai Road, Andheri (W), Mumbai – 400053.
Other Info - ZEN0627
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