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  3. Zestril 5 mg Tablet 15's

Zestril 5 mg Tablet 15's, Pack of 15 TabletS
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Composition :

LISINOPRIL-5MG

Manufacturer/Marketer :

Astra Zeneca Pharma India Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Zestril 5 mg Tablet

Zestril 5 mg Tablet is used to treat high blood pressure (hypertension) and reduce the risk of having a heart attack, stroke, or heart failure. High blood pressure is a chronic condition in which the pressure in the blood vessels is high. The blood exerts high pressure on blood vessel walls (arteries), leading to hypertension. Heart failure can occur when your heart cannot pump the blood sufficiently required for the body's remaining. A heart attack or stroke is the blockage of blood flow to the heart muscle. The blockade usually occurs due to fat/cholesterol build-up in the coronary artery (which supplies blood to the heart). 

Zestril 5 mg Tablet contains lisinopril, which works by lowering the body’s production of substances that could increase blood pressure. Zestril 5 mg Tablet relaxes and widens the blood vessels, making it easier for the heart to pump blood to all parts of the body, lowering the raised blood pressure and reducing the risk of heart failure, heart attack or stroke.

Take Zestril 5 mg Tablet with or without food. Do not chew, crush, or break the tablet; swallow it as a whole with a glass of water. Take Zestril 5 mg Tablet at the same time every day. Sometimes, you may experience common side effects like headache, dizziness, fatigue, and cough. Most of these side effects do not require medical attention and resolve gradually over time. Talk to your doctor if you experience these side effects persistently.

To treat your condition effectually, continue taking Zestril 5 mg Tablet for as long as your doctor has prescribed it. Try not to stop taking it on your own as it may cause a sudden increase the blood pressure, chest pain or heart attack. Regular monitoring of blood pressure, electrolyte levels and kidney functioning is advised while taking Zestril 5 mg Tablet . It would help to consume low table salt (sodium chloride) and a low-fat diet while taking Zestril 5 mg Tablet . Avoid taking Zestril 5 mg Tablet if you are pregnant or breastfeeding. Talk to your doctor. They may prescribe you alternate medicine. Zestril 5 mg Tablet is not recommended for children below 18 years of age as efficacy and safety have not been established.

Directions for Use

• Zestril 5 mg Tablet can be taken with or without food as advised by your doctor.• Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.• Swallow Zestril 5 mg Tablet as a whole with a glass of water.• Do not chew, crush or break it.

Medicinal Benefits

Zestril 5 mg Tablet relaxes and widens the blood vessels, making it easier for the heart to pump blood to all body parts. This helps lower blood pressure and the risk of a heart attack or stroke. Zestril 5 mg Tablet helps reduce standing and lying down blood pressure without any orthostatic effect (a sudden decrease in blood pressure might occur when a person stands up suddenly). However, when dehydrated, Zestril 5 mg Tablet may show an orthostatic effect. Continued usage of Zestril 5 mg Tablet reduces the severity of heart failure, hospitalization rate and symptoms such as weakness and shortness of breath. Zestril 5 mg Tablet is used alone or in combination with other medicines to treat high blood pressure.

How Zestril 5 mg Tablet Works

Zestril 5 mg Tablet contains lisinopril, which works by lowering the body's production of substances that could increase blood pressure. Zestril 5 mg Tablet relaxes and widens the blood vessels, making it easier for the heart to pump blood to all parts of the body, lowering the raised blood pressure and reducing the risk of heart failure, heart attack or stroke.

Storage

Store in a cool and dry place away from sunlight
Side effects of Zestril 5 mg Tablet
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
Managing Low Blood Pressure Triggered by Medication: Expert Advice:
  • If you experience low blood pressure symptoms like dizziness, lightheadedness, or fainting while taking medication, seek immediate medical attention.
  • Make lifestyle modifications and adjust your medication regimen under medical guidance to manage low blood pressure.
  • As your doctor advises, regularly check your blood pressure at home. Record your readings to detect any changes and share them with your doctor.
  • Fluid intake plays a vital role in managing blood pressure by maintaining blood volume, regulating blood pressure, and supporting blood vessel function. Drinking enough fluids helps prevent dehydration, maintain electrolyte balance, and regulate fluid balance.
  • Take regular breaks to sit or lie down if you need to stand for long periods.
  • When lying down, elevate your head with extra pillows to help improve blood flow.
  • Avoid heavy exercise or strenuous activities that can worsen low blood pressure.
  • Wear compression socks as your doctor advises to enhance blood flow, reduce oedema, and control blood pressure.
  • If symptoms persist or worsen, or if you have concerns about your condition, seek medical attention for personalized guidance and care.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
Here are the seven steps to manage medication-triggered Dyspnea (Difficulty Breathing or Shortness of Breath):
  • Tell your doctor immediately if you experience shortness of breath after taking medication.
  • Your doctor may adjust the medication regimen or dosage or give alternative medical procedures to minimize the symptoms of shortness of breath.
  • Monitor your oxygen levels and breathing rate regularly to track changes and potential side effects.
  • For controlling stress and anxiety, try relaxation techniques like deep breathing exercises, meditation, or yoga.
  • Make lifestyle changes, such as quitting smoking, exercising regularly, and maintaining a healthy weight.
  • Seek emergency medical attention if you experience severe shortness of breath, chest pain, or difficulty speaking.
  • Follow up regularly with your doctor to monitor progress, adjust treatment plans, and address any concerns or questions.
Here are the steps to manage the medication-triggered Cough:
  • Tell your doctor about the cough symptoms you're experiencing, which may be triggered by your medication.
  • Your doctor may adjust your treatment plan by changing your medication, adding new medications, or providing guidance on managing your cough symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Stay hydrated by drinking plenty of fluids, such as water, tea, or soup, to help thin out mucus and soothe your throat.
  • Get plenty of rest and engage in stress-reducing activities to help your body recover. If your cough persists or worsens, consult your doctor for further guidance.
Here are the few steps for dealing with itching caused by drug use:
  • Report the itching to your doctor immediately; they may need to change your medication or dosage.
  • Use a cool, damp cloth on the itchy area to help soothe and calm the skin, reducing itching and inflammation.
  • Keep your skin hydrated and healthy with gentle, fragrance-free moisturizers.
  • Try not to scratch, as this can worsen the itching and irritate your skin.
  • If your doctor prescribes, you can take oral medications or apply topical creams or ointments to help relieve itching.
  • Track your itching symptoms and follow your doctor's guidance to adjust your treatment plan if needed. If the itching persists, consult your doctor for further advice.

What if I have taken an overdose of Zestril 5 mg Tablet

Do not take more than the prescribed dose of Zestril 5 mg Tablet as it may cause overdose. The symptoms of overdose include lightheadedness and fainting. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

Do not take Zestril 5 mg Tablet if you are allergic to Zestril 5 mg Tablet or any of its contents. Talk to your doctor if you have heart, kidney or liver problems. Zestril 5 mg Tablet may sometimes cause lower blood pressure than normal, especially in dehydrated people who take diuretics (medicines to treat oedema) and low sodium levels. Regularly check your blood pressure levels to avoid any risks. Avoid taking Zestril 5 mg Tablet if you are pregnant or breastfeeding. Talk to your doctor. They may prescribe you alternate medicine. Zestril 5 mg Tablet is not recommended for children below 18 years of age as efficacy and safety have not been established. Inform your doctor about your medications and your health condition to rule out any unpleasant side effects. Consult your doctor if you have lost a lot of body fluids through vomiting, diarrhoea, or sweating more than normal or if you are taking low water tablets to treat oedema (diuretics), or if you undergo dialysis. Stop taking Zestril 5 mg Tablet one day before receiving an anaesthetic to undergo any surgery or dental procedure. Inform your doctor that you are taking Zestril 5 mg Tablet . Regular monitoring of blood pressure, electrolyte levels and kidney functioning is advised while taking Zestril 5 mg Tablet .

Drug-Drug Interactions

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LisinoprilAliskiren
Critical
LisinoprilPotassium chloride
Severe

Drug-Drug Interactions

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LisinoprilAliskiren
Critical
How does the drug interact with Zestril 5 mg Tablet:
Combining Aliskiren with Zestril 5 mg Tablet can increase the potassium levels in the blood.

How to manage the interaction:
Although taking Aliskiren and Zestril 5 mg Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, consult a doctor if you experience symptoms including weakness, tiredness, confusion, numbness or tingling, and irregular heartbeats. Do not discontinue any medications without a doctor's advice.
LisinoprilPotassium chloride
Severe
How does the drug interact with Zestril 5 mg Tablet:
Taking Potassium chloride with Zestril 5 mg Tablet can increase the risk of high potassium levels which may increase the risk of side effects.

How to manage the interaction:
Although taking Zestril 5 mg Tablet and Potassium chloride together can cause an interaction, it can be taken if a doctor has suggested it. However, consult the doctor if you experience nausea, vomiting, weakness, confusion, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. Do not discontinue any medications without a doctor's advice.
LisinoprilOlmesartan medoxomil
Severe
How does the drug interact with Zestril 5 mg Tablet:
Coadministration of Olmesartan medoxomil with Zestril 5 mg Tablet may increase potassium levels in the blood.

How to manage the interaction:
Although taking olmesartan medoxomil together with Zestril 5 mg Tablet may lead to an interaction but can be taken if prescribed by the doctor. However, consult the doctor if you experience nausea, vomiting, weakness, confusion, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without talking to a doctor.
LisinoprilCandesartan
Severe
How does the drug interact with Zestril 5 mg Tablet:
Taking Zestril 5 mg Tablet with candesartan can increase the risk of high potassium levels.

How to manage the interaction:
Taking Zestril 5 mg Tablet with Candesartan together can possibly result in an interaction, but it can be taken if your doctor has advised it. It's important to keep an eye on your blood pressure regularly. If you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without talking to a doctor.
LisinoprilTrimethoprim
Severe
How does the drug interact with Zestril 5 mg Tablet:
Taking Zestril 5 mg Tablet with Trimethoprim may increase potassium levels in the blood.

How to manage the interaction:
Although taking Trimethoprim and Zestril 5 mg Tablet together can evidently cause an interaction, it can be taken if your doctor has suggested it. However, consult the doctor immediately if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without consulting doctor.
LisinoprilLosartan
Severe
How does the drug interact with Zestril 5 mg Tablet:
Coadministration of Losartan with Zestril 5 mg Tablet can increase potassium levels.

How to manage the interaction:
Taking Losartan with Zestril 5 mg Tablet together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, or irregular heartbeat, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
LisinoprilPotassium acetate
Severe
How does the drug interact with Zestril 5 mg Tablet:
Combining Potassium acetate with Zestril 5 mg Tablet can increase the risk of hyperkalemia(high potassium levels in blood).

How to manage the interaction:
Although taking Zestril 5 mg Tablet and Potassium acetate together can evidently cause an interaction, it can be taken if your doctor has suggested it. However, consult your doctor if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without a doctor's advice.
LisinoprilAllopurinol
Severe
How does the drug interact with Zestril 5 mg Tablet:
Co-administration of Allopurinol with Zestril 5 mg Tablet may increase the risk of severe allergic reactions and infections.

How to manage the interaction:
Although there is a possible interaction between Allopurinol and Zestril 5 mg Tablet, you can take these medicines together if prescribed by your doctor. However, if you develop throat tightness, shortness of breath, itching, rash, swelling of the face, lips, or tongue, fever, and/or muscle pain or weakness chills, sore throat, extreme tiredness, body pains, consult a doctor. Do not discontinue any medications without consulting a doctor.
Lisinoprilpotassium phosphate
Severe
How does the drug interact with Zestril 5 mg Tablet:
Taking Zestril 5 mg Tablet with potassium phosphate may increase potassium levels in the blood.

How to manage the interaction:
Co-administration of Zestril 5 mg Tablet with potassium phosphate can possibly result in an interaction, but it can be taken if your doctor has advised it. However, consult the doctor immediately if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without consulting doctor.
LisinoprilAmiloride
Severe
How does the drug interact with Zestril 5 mg Tablet:
Zestril 5 mg Tablet combined with amiloride may cause a rise in potassium levels in your blood.

How to manage the interaction:
Although taking amiloride and Zestril 5 mg Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, consult a doctor if you experience symptoms including weakness, tiredness, confusion, numbness or tingling, and irregular heartbeats. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

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LISINOPRIL-5MGPotassium rich foods
Moderate

Drug-Food Interactions

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LISINOPRIL-5MGPotassium rich foods
Moderate
Common Foods to Avoid:
Lentils, Orange Juice, Oranges, Raisins, Potatoes, Salmon Dried, Spinach, Sweet Potatoes, Tomatoes, Coconut Water, Beans, Beetroot, Broccoli, Bananas, Apricots, Avocado, Yogurt

How to manage the interaction:
Consuming potassium rich diet when on treatment with Zestril 5 mg Tablet can increase the potassium levels in the blood. Although there is a possible interaction, Zestril 5 mg Tablet can be taken on doctor's advice with limiting potassium-containing food. If you experience any unusual effects like weakness, tiredness, confusion, numbness or tingling, and irregular heartbeats, consult a doctor. Do not discontinue any medication without doctor's advise.

Diet & Lifestyle Advise

  • You are advised to consume low salt and low-fat diet while taking Zestril 5 mg Tablet .

  • Regular exercise is also recommended to complement treatment with Zestril 5 mg Tablet .

  • Eat a diet rich in whole grains, vegetables, and fruits.

  • Avoid smoking and alcohol consumption.

  • Maintain a healthy weight with proper diet and exercise.

  • Managing stress with meditation, yoga, and massage would also help treat high blood pressure.

Habit Forming

No

Therapeutic Class

ACE INHIBITORS

Zestril 5 mg Tablet Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Unsafe

You are recommended to avoid alcohol consumption while taking Zestril 5 mg Tablet to avoid unpleasant side-effects. Alcohol intake might interfere with the working of Zestril 5 mg Tablet . Please consult your doctor if you have any concerns regarding this.

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Pregnancy

Unsafe

It is not recommended to take Zestril 5 mg Tablet while you are pregnant. Please consult your doctor if you have any concerns regarding this, your doctor will decide whether Zestril 5 mg Tablet can be given to pregnant women or not.

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Breast Feeding

Unsafe

It is not recommended to take Zestril 5 mg Tablet while you are breastfeeding. Please consult your doctor if you have any concerns regarding this, your doctor will decide whether Zestril 5 mg Tablet can be given to breast-feeding mothers or not.

bannner image

Driving

Caution

Zestril 5 mg Tablet may cause dizziness, do not drive or operate heavy machinery if you feel dizzy.

bannner image

Liver

Caution

Dose adjustment may be needed. Zestril 5 mg Tablet should be used with caution in patients with liver disease. Please consult your doctor if you have any concerns regarding this.

bannner image

Kidney

Caution

Dose adjustment may be needed. Zestril 5 mg Tablet should be used with caution in patients with kidney disease. Please consult your doctor if you have any concerns regarding this.

bannner image

Children

Unsafe

Zestril 5 mg Tablet should not be used by children, as the efficacy and safety have not been established.

Have a query?

FAQs

Zestril 5 mg Tablet is used to treat high blood pressure (hypertension) and reduce the risk of having a heart attack, stroke, or heart failure.

Zestril 5 mg Tablet belongs to the group of medicines called Angiotensin Converting Enzyme (ACE) Inhibitors that works by lowering the body’s production of substances that could increase the blood pressure. Zestril 5 mg Tablet relaxes and widens the blood vessels making it easier for the heart to pump blood to all parts of the body. This helps in lowering the blood pressure and the risk of having a heart attack or stroke.

If you are diabetic you should monitor your blood glucose levels often especially in the first few weeks because Zestril 5 mg Tablet can lower glucose/sugar levels in the blood. However, please consult your doctor before taking Zestril 5 mg Tablet if you are diabetic.

Please do not stop taking Zestril 5 mg Tablet without consulting your doctor on your own as it may lead to rise in blood pressure. Continue taking Zestril 5 mg Tablet for as long as your doctor has prescribed it to you. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Zestril 5 mg Tablet .

Yes, orthostatic hypotension could be a side-effect of Zestril 5 mg Tablet especially in people who are dehydrated. Orthostatic hypotension is a sudden lowering in blood pressure leading to dizziness on standing. If you experience this, do not try to stand up suddenly or start walking, instead lie down and get up slowly only when you feel better. People taking Zestril 5 mg Tablet are advised to regularly monitor their blood pressure levels to avoid such unpleasant events.

Do not overdose on Zestril 5 mg Tablet or any medicine as it could lead to very unpleasant side-effects. Take Zestril 5 mg Tablet only as prescribed by your doctor. Overdose of Zestril 5 mg Tablet can cause increased heartbeat, dizziness, and sleepiness. Rush to your nearest doctor as early as possible if you have overdosed on Zestril 5 mg Tablet .

The most common side-effects of Zestril 5 mg Tablet are headache, nausea, dizziness, weakness, low blood pressure, inflammation of the sinus (sinusitis), shortness of breath, stomach pain, diarrhea, indigestion, skin rash, chest pain, muscle pain, and increased levels of potassium in the blood. Please consult your doctor if you experience any of these side-effects persistently.

Zestril 5 mg Tablet may cause nasal congestion due to dilation of vessels in the nasal mucosa.

Before taking Zestril 5 mg Tablet you should tell your doctor if you are allergic to Zestril 5 mg Tablet or any of its ingredients, if you have diabetes, irregular blood pressure, any problems related to heart, kidneys (if you are on dialysis), liver, or blood, such as a low white blood cell count (neutropenia or agranulocytosis) and if you have recently had diarrhea or vomiting. Let your doctor know about all the other medicines you are taking as they may affect, or be affected by Zestril 5 mg Tablet . If you are pregnant or breastfeeding or are planning to conceive, consult your doctor before taking Zestril 5 mg Tablet to avoid any harmful effects on the baby.

Zestril 5 mg Tablet should be taken at the same time every day to reduce the chances of a missed dose. As it can make you dizzy, your doctor may advise you to take your first dose before bedtime. If you do not feel dizzy after the first dose, you may take Zestril 5 mg Tablet at any time of the day.

Yes, Zestril 5 mg Tablet may make you feel dizzy or lightheaded. If you feel dizzy when you stand up, try getting up very slowly or stay seated until you feel better. To avoid fainting, lie down if you begin to feel dizzy, then sit until you feel better. Avoid driving or using tools or machines and anything requiring concentration while you are feeling dizzy or shaky.

Avoid taking excess salt in your diet and find ways to manage or reduce stress in your life. Take up a hobby, or practice meditation or yoga. Make sure that you have a sound sleep every night as this also lowers stress levels and helps to keep your blood pressure normal. Quit smoking and alcohol consumption as this helps in lowering your blood pressure and preventing heart problems. Exercise regularly and eat a balanced diet that includes fresh fruits, vegetables, whole grains, and fat-free products. If you need any further guidance, consult your doctor to get the maximum benefit of Zestril 5 mg Tablet and to keep yourself healthy.

Some people may experience dry cough, as a side effect of Zestril 5 mg Tablet , which can be persistent and may not be relieved by any medicine. Talk to your doctor if it bothers you or if you have problems falling asleep. Your doctor may advice ways of managing the cough or may recommend another medicine. Remember, do not stop taking Zestril 5 mg Tablet without first consulting your doctor as it may raise your blood pressure and increase the risk of developing a heart attack or stroke. Even if you stop taking Zestril 5 mg Tablet , the cough may take a few days to a month to resolve completely.

There is no proof that Zestril 5 mg Tablet affects either men or women’s fertility. However, if you are planning to conceive, consult your doctor first as Zestril 5 mg Tablet is not recommended in pregnancy.

Zestril 5 mg Tablet may increase blood potassium levels, especially if you have kidney problems, uncontrolled diabetes mellitus, and dehydration. Also, potassium levels may increase in patients who are using potassium salts or medicines or are over 70 years of age. Therefore, if you have any of these conditions and are using Zestril 5 mg Tablet , be cautious and get regular blood tests done to check potassium levels.

Country of origin

India

Manufacturer/Marketer address

Corporate & Registered Office, Block N1, 12th Floor, Manyata Embassy Business Park, Rachenahalli, Outer Ring Road, 560045, Bangalore
Other Info - ZES0001

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

May 20, 2025 | 6:21 PM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://medlineplus.gov/druginfo/meds/a692051.html
  2. https://www.healthline.com/health/lisinopril-oral-tablet
  3. https://www.nhs.uk/medicines/lisinopril/

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