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compositionComposition:CEFIXIME-100MG
prescription
Prescription Medicine
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Zifi 100 Dry Syrup is used to treat a wide range of bacterial infections in children, including infections of the respiratory tract, ear, throat, urinary tract, and other susceptible bacterial infections. It helps relieve symptoms and discomfort caused by infection, supports faster recovery, and prevents the spread of bacteria in the body when taken as prescribed by the doctor.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

CEFIXIME-100MG

Manufacturer/Marketer :

FDC Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

NPPA :

Regulated

About Zifi 100 Dry Syrup

Zifi 100 Dry Syrup is a prescription antibiotic medicine designed to treat a variety of bacterial infections in children. It is commonly prescribed to treat infections of the ears, throat, airways, and urinary tract. By targeting the source of the infection, this medicine helps your child recover safely and comfortably.

For the best results, this medicine must be given at consistent times every day as directed by your doctor. It can be taken with or without food, but giving it with a meal can help prevent a mild upset stomach. Ensuring your child gets plenty of rest and stays hydrated during treatment will also support their recovery.

While highly effective, this medicine can sometimes cause mild side effects such as loose stools or nausea. These usually go away on their own, but you should consult your doctor immediately if your child develops severe watery diarrhoea, a skin rash, or face swelling.

Before starting this medicine, tell your doctor if your child has kidney problems or severe allergies. Do not give this medicine if your child has had a severe allergic reaction to cephalosporin antibiotics or penicillin in the past.

Be sure to inform your healthcare provider about any other medicines your child is taking, as certain drugs or vaccines may interact with this treatment. Always consult your doctor or pharmacist before introducing any new prescription or over-the-counter medicine.

Uses of Zifi 100 Dry Syrup

Zifi 100 Dry Syrup is used to treat bacterial infections in children. The detailed uses of Zifi 100 Dry Syrup are as follows:

  • Middle ear infections: Zifi 100 Dry Syrup helps clear painful bacterial infections in the middle ear, reducing swelling and pressure.
  • Throat and tonsil infections: It eliminates the bacteria responsible for pharyngitis and tonsillitis, relieving painful swallowing.
  • Urinary tract infections: The medicine targets and clears bacteria in the bladder and kidneys, easing pain and discomfort during urination.
  • Chest and lung infections: It treats bacterial bronchitis, helping to relieve chest congestion and coughing.

Key Benefits

Zifi 100 Dry Syrup provides effective treatment for bacterial infections in children by stopping the growth of bacteria and helping the body recover. The key benefits of Zifi 100 Dry Syrup are as follows:

  • Faster Recovery from Infection: By stopping bacterial growth, Zifi 100 Dry Syrup helps reduce fever and relieve symptoms, allowing your child to regain energy and return to normal daily activities sooner.
  • Easy Administration for Children: Available as a dry syrup and suspension, Zifi 100 Dry Syrup is easy to measure and administer to infants and young children who cannot swallow tablets, helping ensure accurate dosing with minimal stress.
Side effects of Zifi 100 Dry Syrup 30 ml
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Here are the step-by-step strategies to manage the side effects of "indigestion" caused by medication usage:
  • Take medications with food (if recommended): It can help prevent stomach distress and indigestion.
  • Eat smaller, more frequent meals: Divide daily food intake into smaller, more frequent meals to ease digestion.
  • Avoid trigger foods: Identify and avoid foods that trigger indigestion, such as spicy, fatty, or acidic foods.
  • Stay upright after eating: Sit or stand upright for at least 1-2 hours after eating to prevent stomach acid from flowing into the oesophagus.
  • Avoid carbonated drinks: Avoid drinking carbonated beverages, such as soda or beer, which can worsen indigestion.
  • Manage stress: To alleviate indigestion, engage in stress-reducing activities like deep breathing exercises or meditation.
  • Consult a doctor if needed: If indigestion worsens or persists, consult a healthcare professional to adjust the medication regimen or explore alternative treatments.

Directions for Use

  • Zifi 100 Dry Syrup can be administered with or without food.
  • Follow your doctor’s instructions on the dosage and timing of this medication to ensure safety.
  • Check the label for directions. Mix the powder with the recommended amount of sterile water, stir well, and administer the prescribed dose to your child.
  • Shake the bottle well before use.

How Zifi 100 Dry Syrup Works

Zifi 100 Dry Syrup contains cefixime, a cephalosporin antibiotic that works by interfering with the formation of the bacterial cell wall. Bacteria need this protective cell wall to survive and multiply. By preventing the cell wall from forming properly, Zifi 100 Dry Syrup causes the bacterial cells to break down and die, stopping the spread of the infection and allowing your child's immune system to eliminate the remaining bacteria.
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Alcohol

Not applicable

It is intended for Children.

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Pregnancy

Not applicable

It is intended for Children.

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Breast Feeding

Not applicable

It is intended for Children.

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Driving

Not applicable

It is intended for Children.

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Liver

Caution

Inform your doctor if your child has liver problems. Your doctor will weigh the benefits and potential risks before prescribing it.

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Kidney

Caution

Inform your doctor if your child has kidney problems. Your doctor will weigh the benefits and potential risks before prescribing it.

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Children

Safe if prescribed

Zifi 100 Dry Syrup is safe for children if prescribed by the doctor. Your paediatrician may prescribe the dose based on the child's condition and age.

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Heart

Consult your doctor

Please consult your doctor before giving Zifi 100 Dry Syrup to your child. Your doctor will prescribe Zifi 100 Dry Syrup if the benefits outweigh the risks.

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Geriatrics

Not applicable

Zifi 100 Dry Syrup is for paediatric patients only.

What if I have taken an overdose of Zifi 100 Dry Syrup

If your child takes more than the prescribed amount, contact your doctor or seek emergency medical help right away.

Diet & Lifestyle Advise

  • Stay Hydrated: Ensure your child drinks plenty of water, broth, or oral rehydration solutions to help prevent dehydration, especially if they experience loose stools.
  • Choose Gentle Foods: Offer bland foods such as rice, toast, applesauce, or crackers if your child has a mild upset stomach after taking the medicine.
  • Avoid Stomach Irritants: Avoid giving your child high-fibre foods, extremely greasy foods, or highly sugary juices while their stomach is settling.
  • Encourage Rest: Make sure your child gets plenty of rest to help their body fight the infection and recover more quickly.
  • Maintain Good Hygiene: Encourage regular handwashing to help prevent the spread of bacteria to others.

Health Queries

Is 5 ml of ZIFI twice a day (morning and bedtime) the correct dose for my 9-month-old daughter who has severe, bloody diarrhea and a fever?

Vikas Singh

Vikas Singh

M Pharmacy

To confirm if 5 ml of Zifi (cefixime) is correct, a doctor needs your daughter's exact weight and the specific strength of the liquid medicine. More importantly, bloody diarrhea and fever in a nine-month-old can quickly lead to dehydration and require immediate evaluation by a pediatrician. Please take her to see a doctor or visit an emergency room right away. They can safely check her hydration, find the exact cause, and ensure she receives the correct treatmen.

My daughter has a cough that only occurs when she is sleeping. Is Zifi 100 suitable for this condition, and what is the recommended dosage and frequency?

Veda Maddala

Veda Maddala

M Pharmacy

A cough that occurs only during sleep is typically caused by allergies, post-nasal drip, or mild asthma-related airway sensitivity, rather than a bacterial infection. Cefixime (the active ingredient in the medication you mentioned) is an antibiotic and is not suitable or effective for these types of coughs. Using antibiotics unnecessarily will not help and can cause side effects. I recommend consulting a pediatrician to evaluate her chest and determine the exact cause. They can prescribe the correct treatment, which may include simple home remedies, anti-allergy medications, or inhalers, rather than an antibiotic.

I've been suffering from a dry cough for the last 3 days. I've taken Zifi CV, Trump D syrup, and Maintain LC for 5 days. Please help me.

Y. Lakshmi Thulasi

Y. Lakshmi Thulasi

Pharm-D (Post baccalaureate)

Antibiotics like Zifi CV are frequently unnecessary and won't be very helpful for a three-day dry cough, which is typically viral or allergic. If the cough persists for more than a week, gets worse, or is accompanied by fever or dyspnea, stop taking unneeded antibiotics, drink warm liquids, utilize steam inhalation, and consult a physician.
health query

Have a query?

How Soon It Starts Working

The time required for Zifi 100 Dry Syrup to start to work: Zifi 100 Dry Syrup ideally shows its action within few hours after administration.

The time for which the effects of Zifi 100 Dry Syrup last: The effect of Zifi 100 Dry Syrup lasts for 12 to 24 hours.

What if you forget to take Zifi 100 Dry Syrup

If you miss a dose, give it as soon as you remember. If it is almost time for the next scheduled dose, skip the missed dose and resume your regular schedule. Do not give a double dose to make up for a missed one.

Storage

•Store the sealed bottle at room temperature (below 25°C) in a dry place. Keep it protected from direct heat, moisture, and light.•Store the prepared liquid suspension in a refrigerator (between 2°C and 8°C). Do not freeze it.

Drug Warnings

  • Inspect Before Use: Check the prepared suspension before every dose. Do not use it if you notice unusual colour changes, clumping, or an off-odour.
  • Use the Measuring Device: Always use the specialised measuring device provided with the product packaging to ensure your child receives the correct dose.
  • Do Not Share the Medicine: Never give this medicine to other children, even if they have similar symptoms, as it should only be used when prescribed by a doctor.
  • Prepare the Suspension Correctly: Do not mix the dry powder with hot water, as heat may affect the medicine. Use cooled, boiled water to prepare the suspension.
  • Keep the Bottle Tightly Closed: Ensure the bottle cap is securely closed after each use to help prevent contamination and maintain the quality of the medicine.

Drug-Drug Interactions

verifiedApollotooltip
  • Blood Thinners (Anticoagulants): Zifi 100 Dry Syrup may increase the effects of blood thinners, such as warfarin, which can raise the risk of bleeding and may require closer monitoring.
  • Live Vaccines: Zifi 100 Dry Syrup may reduce the effectiveness of certain live bacterial vaccines, such as the oral typhoid vaccine.
CefiximeCholera, live attenuated
Severe

Drug-Drug Interactions

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CefiximeCholera, live attenuated
Severe
How does the drug interact with Zifi 100 Dry Syrup 30 ml:
Co-administration of Zifi 100 Dry Syrup 30 ml with Cholera vaccine may reduce the effectiveness of the vaccine.

How to manage the interaction:
Talk to your doctor before receiving the cholera vaccine if you are currently being treated with Zifi 100 Dry Syrup 30 ml or have been treated within the last 14 days. To ensure adequate vaccine response, you should not receive cholera vaccine until at least 14 days after you complete your antibiotic therapy. Do not discontinue the medication without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip

No clinically significant food interactions are known with Zifi 100 Dry Syrup when used as directed. 

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[ANTI- BACTERIALS]

FAQs

Zifi 100 Dry Syrup is used to treat bacterial infections of the ear, nose, sinuses (sinusitis), throat (tonsillitis, pharyngitis), chest and lungs (bronchitis, pneumonia) and urinary system (cystitis and kidney infections).
Zifi 100 Dry Syrup inhibits cell wall synthesis, weakening and ultimately destroying the bacterial cell wall, leading to death. As a result, Zifi 100 Dry Syrup helps to treat bacterial infections.
Zifi 100 Dry Syrup can cause diarrhoea. If your child has diarrhoea that is watery or bloody, call your paediatrician. Do not use anti-diarrhoea medicine unless your paediatrician.
Yes, Zifi 100 Dry Syrup can be used to treat urinary tract infection (UTI). However, it should be taken under the supervision of a healthcare professional.
Zifi 100 Dry Syrup is active against a very wide spectrum of bacteria such as Staphylococcus aureus, Streptococcus pneumoniae, Streptococcus pyogenes (the cause of strep throat), Hemophilus influenzae, Moraxella catarrhalis, E. coli, Klebsiella, Proteus mirabilis, Salmonella, Shigella, and Neisseria gonorrhoeae.
No, you must complete the full course prescribed by your doctor. Stopping early can allow the remaining bacteria to survive, multiply, and become resistant to the antibiotic. Talk to your doctor if you have concerns.
Shake the dry powder to loosen it. Add boiled and cooled water up to the ring mark on the bottle in two portions, shaking well after each addition. Let it sit for a few minutes until a smooth suspension forms. Talk to your pharmacist if you need help.
Yes, you can give this medicine with or without food. Giving it with a meal or milk can help prevent mild stomach upset or nausea in sensitive children.
If your child vomits within 30 minutes of taking a dose, you may need to give the same dose again. If they vomit more than 30 minutes after taking it, do not give an extra dose. Talk to your doctor or pharmacist for specific guidance.
No, this medicine is an antibiotic and only treats bacterial infections. It will not work against viral infections like common colds, flu, or viral coughs. Talk to your doctor for an accurate diagnosis.
Once mixed with water, the liquid suspension is typically safe and effective for up to 14 days when stored in a refrigerator. Always check the packaging instructions or talk to your pharmacist for the exact shelf life.

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Reference

  1. U.S. Food and Drug Administration (FDA). 202091S009Lbl [FDA Prescribing Information]. Silver Spring, MD: FDA; 2024. [Accessed on 02 Jun. 2026]Check here
  2. Electronic Medicines Compendium (EMC). Pil.5534 Patient Information Leaflet (PIL). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026]Check here
  3. Drugs.com Clinical Review Team. Cefixime Drug Interactions Reference. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026]Check here
  4. Cefixime Cefixime. 1986. [Accessed on 29 Mar. 2019]Check here
  5. Cefixime [Drug Label]. 2003. [Accessed on 25 Jul. 2024]Check here
  6. Electronic Medicines Compendium. [Name of Product] – Summary of Product Characteristics [Internet]. London: emc; [Accessed on 2025 Sep 16]Check here
  7. Cefixime capsules: Label information [Internet]. DailyMed (U.S. National Library of Medicine, National Institutes of Health). [Accessed on 2025 Sep 16]Check here

Country of origin

India

Manufacturer/Marketer address

FDC LIMITED, B-8, MIDC Area, Waluj - 431 136, Dist. Aurangabad, Maharashtra
Other Info - ZIF0019
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