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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Zimpril 8mg Tablet belongs to the class of antihypertensive medicines used in the treatment of high blood pressure. It also helps reduce the chances of heart problems such as heart attack and stroke. This medication functions by inhibiting the angiotensin-converting enzyme, which lowers the body's production of angiotensin II, thereby widening the blood vessels and reducing blood pressure. Common side effects include dizziness, weakness, blurred vision, nausea, and cough.
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Manufacturer/Marketer :

Zim Laboratories Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

About Zimpril 8mg Tablet

Zimpril 8mg Tablet is used to treat high blood pressure and heart failure. It is also used to reduce the risk of cardiac events like a heart attack in patients with coronary artery disease and who have had a heart attack and/or surgery to improve the blood supply to the heart. Hypertension (High blood pressure) is a condition in which the force exerted by the blood against the artery walls becomes so high that it causes health problems, such as heart disease.

Zimpril 8mg Tablet contains Perindopril erbumine, an angiotensin-converting enzyme (ACE) inhibitor; it reduces increased blood pressure by blocking a naturally occurring substance known as angiotensin II (that tightens your blood vessels). Zimpril 8mg Tablet relaxes and widens the blood vessels, thereby lowering the blood pressure and making it easier for the heart to pump blood throughout the body. 

Take Zimpril 8mg Tablet as prescribed. Your doctor will advise you on the dosage and duration based on your medical condition. In some cases, you may experience dizziness, headache, weakness, vomiting, and nausea. Most of these side effects of Zimpril 8mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Try not to stop taking this medicine on your own, even if your blood pressure becomes normal; doing so may worsen your condition. Avoid taking Zimpril 8mg Tablet if you are pregnant or breastfeeding. Zimpril 8mg Tablet is not recommended for children below 18 years. Zimpril 8mg Tablet may cause dizziness and weakness, so drive or operate machinery only if you are alert. Keep your doctor informed about your health condition and medications to rule out any interactions.

Uses of Zimpril 8mg Tablet

Treatment of Hypertension, Heart failure and Prevention of heart attack

Directions for Use

Swallow Zimpril 8mg Tablet as a whole with water; do not crush or chew it.

Medicinal Benefits

Zimpril 8mg Tablet is used to treat high blood pressure and heart failure. Additionally, it is also used to reduce the risk of cardiac events like a heart attack in patients with coronary artery disease and who have had a heart attack and/or surgery to improve the blood supply to the heart. Zimpril 8mg Tablet contains Perindopril erbumine, an angiotensin-converting enzyme (ACE) inhibitor; it reduces increased blood pressure by blocking a naturally occurring substance known as angiotensin II (that tightens your blood vessels). Zimpril 8mg Tablet allows constricted blood vessels to relax and, therefore, helps lower high blood pressure.

How Zimpril 8mg Tablet Works

Zimpril 8mg Tablet contains Perindopril erbumine, an angiotensin-converting enzyme (ACE) inhibitor; it reduces increased blood pressure by blocking a naturally occurring substance known as angiotensin II (that tightens your blood vessels). Zimpril 8mg Tablet relaxes and widens the blood vessels, thereby lowering the blood pressure and making it easier for the heart to pump blood throughout the body.

Storage

Store in a cool and dry place away from sunlight
Side effects of Zimpril 8mg Tablet
Here are the steps to manage the medication-triggered Cough:
  • Tell your doctor about the cough symptoms you're experiencing, which may be triggered by your medication.
  • Your doctor may adjust your treatment plan by changing your medication, adding new medications, or providing guidance on managing your cough symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Stay hydrated by drinking plenty of fluids, such as water, tea, or soup, to help thin out mucus and soothe your throat.
  • Get plenty of rest and engage in stress-reducing activities to help your body recover. If your cough persists or worsens, consult your doctor for further guidance.
Managing Low Blood Pressure Triggered by Medication: Expert Advice:
  • If you experience low blood pressure symptoms like dizziness, lightheadedness, or fainting while taking medication, seek immediate medical attention.
  • Make lifestyle modifications and adjust your medication regimen under medical guidance to manage low blood pressure.
  • As your doctor advises, regularly check your blood pressure at home. Record your readings to detect any changes and share them with your doctor.
  • Fluid intake plays a vital role in managing blood pressure by maintaining blood volume, regulating blood pressure, and supporting blood vessel function. Drinking enough fluids helps prevent dehydration, maintain electrolyte balance, and regulate fluid balance.
  • Take regular breaks to sit or lie down if you need to stand for long periods.
  • When lying down, elevate your head with extra pillows to help improve blood flow.
  • Avoid heavy exercise or strenuous activities that can worsen low blood pressure.
  • Wear compression socks as your doctor advises to enhance blood flow, reduce oedema, and control blood pressure.
  • If symptoms persist or worsen, or if you have concerns about your condition, seek medical attention for personalized guidance and care.
  • Limit fruit intake to two servings a day, choose a low-potassium options like apples and strawberries.
  • Restrict starchy vegetables like potatoes and pumpkin to half a cup daily.
  • Avoid or limit foods like tomato products, high-bran cereals, and salty or sugary snacks.
  • Limit dairy products to 200g of yoghurt or 300ml of milk per day.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
  • Skin rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
  • Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
  • Protect your skin from extreme heat and try to apply wet compresses.
  • Soak in the cool bath, which gives a soothing impact to the affected area.

What if I have taken an overdose of Zimpril 8mg Tablet

Do not take more than the prescribed dose of Zimpril 8mg Tablet as it may cause overdose. The symptoms of overdose include sleepiness, dizziness, and pounding heartbeat. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

Do not take Zimpril 8mg Tablet if you are allergic to any of the contents, ACE inhibitors, if you are taking sacubitril, valsartan, or aliskiren. Inform your doctor if you have/had kidney problems, dialysis, heart problems, liver dysfunction, diabetes, dehydration, angioedema, collagen vascular disease, or primary aldosteronism. Consult your doctor if you develop signs of infection or jaundice. Avoid taking Zimpril 8mg Tablet if you are pregnant or breastfeeding. Zimpril 8mg Tablet is not recommended for children below 18years. Zimpril 8mg Tablet may cause dizziness and weakness, so drive or operate machinery only if you are alert. Keep your doctor informed about your health condition and medications to rule out any interactions.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Zimpril 8mg Tablet:
Combining Aliskiren with Zimpril 8mg Tablet can increase the risk of low blood pressure, high potassium levels, and kidney damage.

How to manage the interaction:
Taking Zimpril 8mg Tablet with Aliskiren is not recommended, but can be taken if prescribed by a doctor. However, if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, a weak pulse, or a slow or irregular heartbeat contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Zimpril 8mg Tablet:
Taking Zimpril 8mg Tablet with telmisartan may increase the risk of side effects such as low blood pressure, kidney function impairment, and high blood potassium.

How to manage the interaction:
Although there is a possible interaction, telmisartan can be taken with Zimpril 8mg Tablet if prescribed by the doctor. Consult the prescriber if you experience symptoms of high potassium such as nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, a weak pulse, or a slow or irregular heartbeat. Maintain adequate fluid intake during treatment with these medications. Do not discontinue the medications without consulting a doctor.
How does the drug interact with Zimpril 8mg Tablet:
Taking Zimpril 8mg Tablet with trimethoprim can cause hyperkalemia(high levels of potassium in blood) which can increase the risk of kidney problems and abnormal heart rhythm.

How to manage the interaction:
Co-administration of Zimpril 8mg Tablet with Trimethoprim can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, a weak pulse, or a slow or irregular heartbeat contact your doctor immediately. Do not stop using any medications without a doctor's advice. Do not discontinue any medications without consulting your doctor.
PerindoprilMipomersen
Severe
How does the drug interact with Zimpril 8mg Tablet:
Using Zimpril 8mg Tablet together with mipomersen can increase the risk of liver problems.

How to manage the interaction:
Co-administration of Zimpril 8mg Tablet with Mipomersen can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark urine, pale stools, and/or yellowing of the skin or eyes contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
How does the drug interact with Zimpril 8mg Tablet:
Coadministration of Zimpril 8mg Tablet with Valsartan may increase the risk of side effects (low blood pressure, kidney function impairment, and hyperkalemia (high blood potassium).

How to manage the interaction:
Although taking Zimpril 8mg Tablet together with Valsartan may result in an interaction, they can be taken together if prescribed by a doctor. However, contact a doctor immediately if you experience symptoms such as nausea, vomiting, confusion, numbness, tingling in hands and feet, and irregular heartbeat, contact a doctor. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Zimpril 8mg Tablet:
Co-administration of Allopurinol with Zimpril 8mg Tablet may increase the risk of severe allergic reactions and infections.

How to manage the interaction:
Although there is a possible interaction between Allopurinol and Zimpril 8mg Tablet, you can take these medicines together if prescribed by your doctor. However, if you develop throat tightness, shortness of breath, itching, rash, swelling of the face, lips, or tongue, fever, and/or muscle pain or weakness, signs of infection or experience chills, fever, sore throat, extreme tiredness, body pains, or other flu-like symptoms, contact your doctor immediately . Do not discontinue any medications without consulting a doctor.
How does the drug interact with Zimpril 8mg Tablet:
Using Zimpril 8mg Tablet together with spironolactone may cause hyperkalemia (high potassium level in blood).

How to manage the interaction:
Although taking spironolactone and Zimpril 8mg Tablet together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as weakness, confusion, numbness or tingling, and uneven heartbeats. Do not stop using any medications without consulting doctor.
How does the drug interact with Zimpril 8mg Tablet:
Taking Alprazolam with Zimpril 8mg Tablet shows additive effects which may increase their efficacy and side effects. Increased Alprazolam levels may alter blood pressure.

How to manage the interaction:
Taking Alprazolam with Zimpril 8mg Tablet can show additive efficacy, it can be taken if your doctor has advised it. Contact your doctor immediately if you experience signs such as slurred speech, drowsiness, confusion, blurry visions, severe weakness, or difficulty breathing. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Zimpril 8mg Tablet:
Using Zimpril 8mg Tablet together with dalteparin may increase the risk of side effects of Zimpril 8mg Tablet.

How to manage the interaction:
Taking Zimpril 8mg Tablet with Dalteparin together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, consult your doctor if you experience nausea, vomiting, weakness, confusion, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Zimpril 8mg Tablet:
Using Teriflunomide together with Zimpril 8mg Tablet can increase the risk of liver problems.

How to manage the interaction:
There may be a possibility of interaction between Zimpril 8mg Tablet and Teriflunomide, but it can be taken if prescribed by a doctor. Do not discontinue any medications without first consulting your doctor.

Drug-Food Interactions

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PERINDOPRIL ERBUMINE-8MGPotassium rich foods
Moderate

Drug-Food Interactions

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PERINDOPRIL ERBUMINE-8MGPotassium rich foods
Moderate
Common Foods to Avoid:
Lentils, Orange Juice, Oranges, Raisins, Potatoes, Salmon Dried, Spinach, Sweet Potatoes, Tomatoes, Coconut Water, Beans, Beetroot, Broccoli, Bananas, Apricots, Avocado, Yogurt

How to manage the interaction:
Taking Zimpril 8mg Tablet with potassium-containing foods can increase the risk of hyperkalemia (high potassium levels in the blood). Avoid moderately high or high potassium dietary intake with Zimpril 8mg Tablet, as it can lead to an interaction.

Diet & Lifestyle Advise

  • Do regular physical activity or exercise for at least 150 minutes per week, or about 30 minutes most days of the week.

  • Opt for a diet rich in whole grains, fruits, vegetables, and low-fat dairy products.

  • Limit intake of sodium chloride (table salt) in your daily diet.

  • Quitting smoking is the best strategy to lower the risk of heart disease.

  • Avoid chronic stress as it can raise your blood pressure. Try to enjoy and spend time with your loved ones to cope with stress and practice mindfulness techniques.

  • Try to include heart-healthy omega 3 fatty acid containing food drinks in your daily diet. You can also use low-fat cooking oil like olive oil, soybean oil, canola oil, and coconut oil to lower your elevated blood pressure.

Habit Forming

No

Therapeutic Class

ANTI- HYPERTENSIVES AND ACE INHIBITORS
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Alcohol

Unsafe

Alcohol may enhance the hypotensive (low blood pressure) effect of Zimpril 8mg Tablet. It may also cause increased dizziness. For better advice, you should consult your doctor if you can take Zimpril 8mg Tablet with alcohol.

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Pregnancy

Unsafe

Avoid taking Zimpril 8mg Tablet if you are pregnant, especially if you are more than 3months pregnant as it may cause harm to the developing fetus. Consult your doctor if you are pregnant or planning for pregnancy.

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Breast Feeding

Unsafe

Use of Zimpril 8mg Tablet is not recommended during the breastfeeding.

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Driving

Caution

Zimpril 8mg Tablet may cause blurry vision, dizziness or weakness. Drive or operate machinery only if you are alert.

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Liver

Caution

Rare elevation in liver enzymes (like bilirubin) has been observed while taking Zimpril 8mg Tablet, so it must be taken with caution. If you have a history of liver diseases/conditions, the dose may have to be adjusted by your doctor.

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Kidney

Caution

Zimpril 8mg Tablet to be taken with caution, especially in case of severe kidney disease. The dose may have to be adjusted by your doctor. Zimpril 8mg Tablet should be given with precaution in hemodialysis condition.

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Children

Unsafe

The safety and effectiveness of Zimpril 8mg Tablet in children below 18years have not been established.

Have a query?

FAQs

Zimpril 8mg Tablet is used to treat high blood pressure and heart failure. It is also used to reduce the risk of cardiac events like a heart attack in patients with coronary artery disease and who have had a heart attack and/or surgery to improve the blood supply to the heart.

Zimpril 8mg Tablet relaxes and widens the blood vessels, thereby lowering the blood pressure and making it easier for the heart to pump blood throughout the body.

It is advised to continue taking Zimpril 8mg Tablet even after your blood pressure is under control or becomes normal as blood pressure can shoot up at any time. If you have any discomfort, please consult your doctor immediately.

Zimpril 8mg Tablet might alter potassium levels. Therefore inform your doctor if you are taking food rich in potassium, potassium-containing salt substitutes or over-the-counter potassium supplements.

Light-headedness could be a side-effect of Zimpril 8mg Tablet. It occurs due to low blood pressure leading to dizziness on standing. If you experience this, do not try to stand up suddenly or start walking, instead lie down and get up slowly only when you feel better. People taking Zimpril 8mg Tablet are advised to regularly monitor their blood pressure levels to avoid unpleasant events.

Inform your doctor if you are diabetic as Zimpril 8mg Tablet may cause hypoglycaemia (low blood glucose levels). Regular monitoring of blood sugar levels is advised.

Zimpril 8mg Tablet belongs to the antihypertensive medicines used to treat high blood pressure.

To manage high blood pressure, take your medication as prescribed and make healthy lifestyle choices. Eat a balanced diet, exercise regularly, limit sodium and alcohol, and manage stress. These changes can help lower your blood pressure and improve your overall health.

No, you should not discontinue Zimpril 8mg Tablet without consulting your doctor. Even if you feel better, you should continue to take the medication as directed. Stopping abruptly might result in a sudden rise in blood pressure, leading to significant health issues. Your doctor will assess whether reducing or discontinuing your medication is safe based on your specific condition and blood pressure measurements.

Yes, Zimpril 8mg Tablet may cause dizziness. This is a usual adverse effect, particularly when first starting the medicine. However, discomfort usually fades away after a few days or weeks as your body becomes used to the medicine. If the problem persists, visit your doctor.

The ideal time to take Zimpril 8mg Tablet is typically in the morning. This helps to keep your blood pressure steady throughout the day. However, depending on your specific needs and medications, your doctor may recommend a different time. It's critical to follow their exact directions.

Yes, Zimpril 8mg Tablet can raise potassium levels in the blood. This is because it inhibits the function of angiotensin II, a chemical that ordinarily causes the kidneys to retain sodium while losing potassium. If your potassium levels grow too high, you may experience major health problems, such as irregular heartbeat. Your doctor will likely order specific blood tests to monitor your potassium levels. If your potassium levels are too high, your doctor may change your perindopril dose or prescribe a medicine to help lower them.

Dry cough is a common side effect of Zimpril 8mg Tablet. It's often a bother but usually resolves on its own within a few weeks. Talk to your doctor if the cough becomes severe or interferes with your daily activities. They may be able to adjust your dosage or prescribe a different medication.

There's no clear evidence to suggest that taking perindopril reduces fertility in either men or women. Seek medical attention if you have any concerns regarding this.

No, if you become pregnant while taking perindopril, inform your doctor immediately. The medication can harm the developing fetus.

Zimpril 8mg Tablet may interact with other drugs, increasing or lowering their efficacy or producing adverse effects. It is critical to tell your doctor about all medications you are taking, including over-the-counter treatments, herbal supplements, and prescription prescriptions.

Before using this medication, you should inform your doctor about your medical history, including any ongoing medicines, to avoid potential interactions and minimise side effects.

Take the missed dose as soon as you remember unless it's almost time for your next dose. In this case, skip the missed dose and take your next dose at the regular time. Never take a double dose to make up for a missed one.

Alcohol may enhance the hypotensive (low blood pressure) effect of Zimpril 8mg Tablet. It may also cause increased dizziness. For better advice, you should consult your doctor if you can take Zimpril 8mg Tablet with alcohol.

The symptoms of overdose include sleepiness, dizziness, and a pounding heartbeat. If you suspect you have taken an overdose or notice signs of overdose, please consult a doctor immediately.

No, Zimpril 8mg Tablet should be swallowed whole with a glass of water. Crushing or chewing it may affect the medication's absorption.

Zimpril 8mg Tablet can sometimes affect kidney function. Regular monitoring of kidney function is important, especially if you have pre-existing kidney problems.

Yes, Zimpril 8mg Tablet can help reduce the risk of heart attack and stroke in people with high blood pressure or other cardiovascular risk factors.

Store Zimpril 8mg Tablet in a dry place, away from heat and direct sunlight. Keep them out of the reach of children and pets.

Your doctor will determine the appropriate frequency of follow-up appointments based on your individual needs and blood pressure control. Regular monitoring is essential to ensure the medication is working effectively.

Yes, adopting a healthy lifestyle can enhance the benefits of Zimpril 8mg Tablet. This includes maintaining a balanced diet, exercising regularly, managing stress, and limiting alcohol consumption.

Country of origin

India
Other Info - ZI98709

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