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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Zinepra 10 Tablet is used to treat migraine. It contains Propranolol and Flunarizine which improves blood flow and dilates blood vessels in the brain, thereby preventing headaches caused due to migraine. It effectively treats and reduces the severity and frequency of migraine headaches. Also, it is also used to treat vertigo (spinning sensation). It may cause common side effects such as dry weight gain, slow heart rate, tiredness, depression, drowsiness, abnormal dreams, and cold extremities (hands and feet). Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Manufacturer/Marketer :

La Renon Healthcare Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Zinepra 10 Tablet

Zinepra 10 Tablet is used to treat migraine. Migraine is a medical condition that involves severe throbbing pain or a pulsing sensation on one side of the head. Severe and recurrent headaches are one of the characteristic symptoms of migraine. Its symptoms include nausea, vomiting, difficulty speaking, numbness or tingling, and sensitivity to light and sound.

Zinepra 10 Tablet consists of 'Propranolol' (beta-blocker) and 'Flunarizine' (calcium channel blocker). Propranolol has anxiolytic (anxiety-reducing), anti-arrhythmic (treats abnormal heart rhythms), and antihypertensive (reduces blood pressure) properties. Propranolol works by reducing cerebral (brain) blood flow by directly acting on the brain's blood vessels. It also inhibits the cortical spreading of depression and electrical activity in the brain that causes pain and inflammation. It effectively treats and reduces the severity and frequency of migraine headaches. Flunarizine belongs to the class of calcium channel blockers. It improves blood flow and dilates blood vessels in the brain, thereby preventing headaches caused by migraine. It is also used to treat vertigo (spinning sensation).

Your doctor will decide the dose and duration based on the severity of your pain. Common side effects of Zinepra 10 Tablet include dry weight gain, slow heart rate, tiredness, depression, drowsiness, abnormal dreams, and cold extremities (hands and feet). These side effects are not familiar to everyone and vary individually. If you notice any side effects that are not manageable, please consult your doctor.

Let your doctor know if you use any prescription and non-prescription medications you are taking, including other vitamins, before starting Zinepra 10 Tablet . Zinepra 10 Tablet may cause weight gain in some cases, so avoid eating junk and eat a healthy, balanced diet, including home-cooked food. Consult your doctor before taking Zinepra 10 Tablet if you are pregnant, planning for pregnancy or breastfeeding. Avoid consuming alcohol along with Zinepra 10 Tablet as it could lead to increased drowsiness.

Uses of Zinepra 10 Tablet

Treatment of Migraine.

Directions for Use

Swallow Zinepra 10 Tablet as a whole with a glass of water; do not chew, crush or break it.

Medicinal Benefits

Zinepra 10 Tablet is used to treat migraine. It consists of 'Propranolol' and 'Flunarizine'. Propranolol is a beta-blocker and has anxiolytic (anxiety-reducing), anti-arrhythmic, and antihypertensive properties. It works by lowering cerebral (brain) blood flow and inhibits cortical spreading depression, as well as electrical activity in the brain that causes pain and inflammation. It reduces the severity and frequency of migraine headaches. Flunarizine is a channel blocker that improves blood flow and dilates blood vessels in the brain, thereby preventing headaches caused by migraine. 

How Zinepra 10 Tablet Works

Zinepra 10 Tablet consists of 'Propranolol' (beta-blocker) and 'Flunarizine' (calcium channel blocker). Propranolol has anxiolytic (anxiety-reducing), anti-arrhythmic (treats abnormal heart rhythms), and antihypertensive (reduces blood pressure) properties. Propranolol works by reducing cerebral (brain) blood flow by directly acting on the brain's blood vessels. It also inhibits the cortical spreading of depression and electrical activity in the brain that causes pain and inflammation. It effectively treats and reduces the severity and frequency of migraine headaches. Flunarizine belongs to the class of calcium channel blockers. It improves blood flow and dilates blood vessels in the brain, thereby preventing headaches caused by migraine.

Storage

Store in a cool and dry place away from sunlight

What if I have taken an overdose of Zinepra 10 Tablet

Do not take more than the prescribed dose of Zinepra 10 Tablet as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

Inform your doctor if you have any history of liver or kidney diseases, breathing problems (asthma, bronchitis, emphysema), diabetes, heart failure, heart rhythm problems (sinus bradycardia, Wolff-Parkinson-White syndrome, atrioventricular block), overactive thyroid, blood circulation problems (Raynaud's disease), adrenal gland tumour (pheochromocytoma), depression, metabolic acidosis (excess acid in the blood), and myasthenia gravis (muscle weakness) before starting Zinepra 10 Tablet . Please consult your doctor if you are pregnant and planning to conceive if the doctor advised you Zinepra 10 Tablet . Avoid consuming alcohol along with Zinepra 10 Tablet as it could lead to increased dizziness and drowsiness.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Zinepra 10 Tablet:
Coadministration of thioridazine with Zinepra 10 Tablet may increase the blood levels of thioridazine and cause an irregular heart rhythm that may be serious.

How to manage the interaction:
Although there is an interaction between Zinepra 10 Tablet and thioridazine, they can be taken together if prescribed by a doctor. However, if you experience sudden dizziness, lightheadedness, fainting, and shortness of breath contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Zinepra 10 Tablet:
Coadministration of Aminophylline with Zinepra 10 Tablet together can make Zinepra 10 Tablet less effective and increase the effects of aminophylline.

How to manage the interaction:
Taking Aminophylline with Zinepra 10 Tablet can cause an interaction. However, it can be taken only if a doctor has advised it. If you experience nausea, vomiting, sleeplessness, restlessness, irregular heartbeats, or difficulty in breathing, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Zinepra 10 Tablet:
Co-administration of Epinephrine with Zinepra 10 Tablet may cause severe high blood pressure and reduced heart rate.

How to manage the interaction:
Taking Epinephrine with Zinepra 10 Tablet can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Zinepra 10 Tablet:
Combining ceritinib with Zinepra 10 Tablet can decrease heart rate and increase the risk of an irregular heart rhythm.

How to manage the interaction:
Although taking Posaconazole together with Ceritinib can possibly result in an interaction, they can be taken together if prescribed by your doctor. However, consult your doctor if you experience lightheadedness, generalized weakness, dizziness, or shortness of breath, consult a doctor immediately. Do not stop using any medications consulting a doctor.
How does the drug interact with Zinepra 10 Tablet:
Using Zinepra 10 Tablet together with salmeterol may reduce the benefits of both medications, since they have opposing effects in the body. In addition, Zinepra 10 Tablet can sometimes cause breathing problems.

How to manage the interaction:
Although taking Zinepra 10 Tablet together with Salmeterol can result in an interaction, they can be taken together if prescribed by your doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Zinepra 10 Tablet:
Co-administration of Clonidine and Zinepra 10 Tablet may lower blood pressure and slower heart rate.

How to manage the interaction:
Although there is a possible interaction between Clonidine and Zinepra 10 Tablet, you can take these medicines together if prescribed by your doctor. However, if you experience headaches, slow heartbeat, dizziness, or feeling like you might pass out, contact your doctor.
How does the drug interact with Zinepra 10 Tablet:
Using fingolimod with Zinepra 10 Tablet can cause an excessive lowering of heart rate and can lead to other heart problems.

How to manage the interaction:
Although taking Zinepra 10 Tablet together with Fingolimod can possibly result in an interaction, they can be taken together if prescribed by your doctor. However, consult your doctor immediately if you experience lightheadedness, fainting, shortness of breath, chest pain, or heart palpitations. Do not stop using any medicines without consulting a doctor.
PropranololIndacaterol
Severe
How does the drug interact with Zinepra 10 Tablet:
Using Zinepra 10 Tablet together with indacaterol may reduce the benefits of both medications, since they have opposing effects in the body. In addition, Zinepra 10 Tablet can cause breathing problems.

How to manage the interaction:
Although taking Zinepra 10 Tablet together with Indacaterol can possibly result in an interaction, they can be taken together if prescribed by your doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Zinepra 10 Tablet:
Using Zinepra 10 Tablet and verapamil together may lead to increased side effects.

How to manage the interaction:
Although taking Zinepra 10 Tablet together with Verapamil can result in an interaction, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience fatigue, headache, fainting, swelling of the extremities, weight gain, shortness of breath, chest pain, increased or decreased heartbeat, or irregular heartbeat. Do not stop taking any medication without consulting a doctor.
How does the drug interact with Zinepra 10 Tablet:
Coadministration of tizanidine and Zinepra 10 Tablet may further lower your blood pressure due to the additive effect.

How to manage the interaction:
Although taking Zinepra 10 Tablet together with Tizanidine can possibly result in an interaction, they can be taken together if prescribed by your doctor. However, consult your doctor if you experience headache, dizziness, lightheadedness, fainting, and/or changes in heart rate. Do not stop taking any medication without consulting your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Avoid chocolates, junk food, cheese, processed food, alcohol, and smoking. Instead, eat a healthy diet and do regular exercise to avoid weight gain caused due to Zinepra 10 Tablet .
  • Avoid loud music, extreme temperatures, bright lights, and noisy places as it can increase headache.
  • You can try increasing your mindfulness by doing yoga, meditation, mindfulness-based cognitive therapy, and stress reduction techniques.
  • Drink enough water to stay hydrated and limit or avoid alcohol and caffeine to relieve headaches.
  • Include a diet rich in whole grains, vegetables, and fruits. This is a healthier option than eating a lot of simple carbohydrates found in processed foods.
  • You can include antioxidants in your daily diet like ashwagandha, omega-3 fatty acids, green tea, and lemon balm.
  • Try to spend time with your friends and family. Having a strong social network may help you lower your risk of anxiety.

Habit Forming

No

Therapeutic Class

ANTIMIGRAINE AGENTS
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Alcohol

Unsafe

You are recommended to avoid alcohol consumption while taking Zinepra 10 Tablet . Alcohol intake, along with Zinepra 10 Tablet , may cause increased dizziness and drowsiness.

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Pregnancy

Caution

Please consult your doctor if you are pregnant or planning to conceive before using Zinepra 10 Tablet .

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Breast Feeding

Caution

Please consult your doctor before taking Zinepra 10 Tablet if you are a lactating mother.

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Driving

Caution

Zinepra 10 Tablet may make you feel drowsy. Do not drive or operate machinery if you experience drowsiness.

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Liver

Caution

Therapy with propranolol should be administered cautiously in patients with liver disease. Please consult your doctor if you have a history of liver impairment/liver disease.

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Kidney

Caution

Plasma clearance of Propranolol in Zinepra 10 Tablet is reduced in patients with renal failure. Please consult your doctor if you have a history of kidney impairment/kidney disease.

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Children

Safe if prescribed

Zinepra 10 Tablet is safe to use for children below 12 years of age when prescribed by the doctor.

Have a query?

FAQs

Zinepra 10 Tablet belongs to the class of anti-migraine drugs used to treat migraine.

Zinepra 10 Tablet is a combination of two drugs: Propranolol and Flunarizine. Zinepra 10 Tablet treats migraine by reducing the blood flow to the brain, and inhibits cortical spreading depression, electrical activity in the brain that causes pain and inflammation.

Zinepra 10 Tablet may sometimes cause weight gain during its prolonged use. It is always advised to maintain a well-balanced, healthy diet and exercise regularly.

Zinepra 10 Tablet does not work for a sudden migraine attack. It is helpful in only preventing new episodes of migraine headaches. Please let your doctor know if you have sudden attacks to be prescribed other suitable medications.

Zinepra 10 Tablet is contraindicated in asthma, slow heart rate, abnormal heart rhythms, heart conditions like AV (Atrioventricular) block or sick sinus syndrome, depression, and Parkinson's disease. Please consult your doctor before starting Zinepra 10 Tablet if you have a medical history.

Your doctor will prescribe Zinepra 10 Tablet to prevent any new episodes of migraine. Please do not stop taking this medicine unless advised by your doctor since it may lead to recurrent episodes of migraine. Zinepra 10 Tablet also contains Propranolol, and its sudden withdrawal may cause sweating, shaking, irregular heartbeat, and worsening of underlying angina or heart attack. Hence, do not stop using Zinepra 10 Tablet unless advised by your doctor.

Country of origin

INDIA

Manufacturer/Marketer address

Behind Rajpath Club, Kensville Road, Opp. Infostretch Building, Off S.G. Highway, Ahmedabad- 380059, Gujarat- India
Other Info - ZIN0341

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