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  3. Zipsal-40 Capsule 10's

Zipsal-40 Capsule 10's, Pack of 10 TabletS
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Written By Veda Maddala , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Zipsal-40 Capsule is used to treat schizophrenia and bipolar disorder. It contains Ziprasidone which works by blocking the effects of chemical messengers (dopamine and serotonin) in the brain and improves thinking mood, and behaviour. In some cases, this medicine may cause side effects such as drowsiness, dizziness, light-headedness, weakness, nausea, vomiting, runny nose, and cough. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Composition :

ZIPRASIDONE-40MG

Manufacturer/Marketer :

Bioapoyo

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Zipsal-40 Capsule

Zipsal-40 Capsule belongs to a group of medicines called 'atypical antipsychotics,' primarily used to treat schizophrenia and manic depression (bipolar disorder). Schizophrenia is a mental condition in which the person may feel, hear or see things that are not there (hallucinations), believe things that are not true, and feel unusually suspicious or confused. Manic depression or bipolar disorder is a serious brain disorder in which a person experiences extreme mood swings (variance in thinking) and frequent mood and behavioural changes.

Zipsal-40 Capsule contains 'Ziprasidone’ that works by blocking the effects of chemical messengers (dopamine and serotonin) in the brain and improves thinking mood, and behaviour. Zipsal-40 Capsule helps in clear thinking and decreases hallucinations. Zipsal-40 Capsule is used for treating manic episodes of bipolar disorder and agitation in schizophrenia.

Take this as prescribed by your doctor. Your doctor will decide the dose and duration based on your medical condition and response to treatment. Common side effects of Zipsal-40 Capsule include drowsiness, dizziness, light-headedness, weakness, nausea, vomiting, runny nose, and cough. These side effects are not familiar to everyone and vary individually. If you notice any side effects that are not manageable, please consult your doctor.

Ziprasidone is not recommended for treatment in patients with Dementia-Related Psychosis. If you are using any prescription and non-prescription medications, let your doctor know before starting Zipsal-40 Capsule . Inform your doctor beforehand if you have a history of liver or kidney diseases, heart problems, breathing problems, diabetes, obesity, and fits. If you are pregnant, planning to conceive or a breastfeeding mother, inform your doctor before starting Zipsal-40 Capsule . Avoid consuming alcohol during the course as it can make you dizzy or drowsy. Do not drive or operate machinery while using Zipsal-40 Capsule since it can make you sleepy.

Uses of Zipsal-40 Capsule

Treatment of Schizophrenia and Manic depression (bipolar disorder).

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Zipsal-40 Capsule is used to treat schizophrenia and manic depression (bipolar disorder). Zipsal-40 Capsule effectively treats manic episodes of bipolar disorder and agitation in schizophrenia. It contains 'Ziprasidone' that belongs to the class of atypical antipsychotics. Zipsal-40 Capsule works by restoring the balance of chemical messengers (dopamine and serotonin) in the brain. It is also known to improve thinking, mood and behaviour. Zipsal-40 Capsule helps in clear thinking and relieves the psychotic symptoms like delusions and hallucinations.

How Zipsal-40 Capsule Works

Zipsal-40 Capsule contains 'Ziprasidone’ that works by blocking the effects of chemical messengers (dopamine and serotonin) in the brain and improves thinking mood, and behaviour. Zipsal-40 Capsule helps in clear thinking and decreases hallucinations. Zipsal-40 Capsule is used for treating manic episodes of bipolar disorder and agitation in schizophrenia.

Storage

Store in a cool and dry place away from sunlight
Side effects of Zipsal-40 Capsule
  • Avoid driving or operating machinery or activities that require high focus until you know how the medication affects you.
  • Maintain a fixed sleeping schedule, create a relaxing bedtime routine and ensure your sleeping space is comfortable to maximize your sleep quality.
  • Limit alcohol and caffeine as these may worsen drowsiness and disturb sleep patterns.
  • Drink plenty of water as it helps with alertness and keeps you hydrated and for overall well-being.
  • Moderate physical activity can improve energy levels, but avoid intense workouts right before bedtime.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.
Here are the step-by-step strategies to manage the side effects of "indigestion" caused by medication usage:
  • Take medications with food (if recommended): It can help prevent stomach distress and indigestion.
  • Eat smaller, more frequent meals: Divide daily food intake into smaller, more frequent meals to ease digestion.
  • Avoid trigger foods: Identify and avoid foods that trigger indigestion, such as spicy, fatty, or acidic foods.
  • Stay upright after eating: Sit or stand upright for at least 1-2 hours after eating to prevent stomach acid from flowing into the oesophagus.
  • Avoid carbonated drinks: Avoid drinking carbonated beverages, such as soda or beer, which can worsen indigestion.
  • Manage stress: To alleviate indigestion, engage in stress-reducing activities like deep breathing exercises or meditation.
  • Consult a doctor if needed: If indigestion worsens or persists, consult a healthcare professional to adjust the medication regimen or explore alternative treatments.
  • Skin rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
  • Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
  • Protect your skin from extreme heat and try to apply wet compresses.
  • Soak in the cool bath, which gives a soothing impact to the affected area.

What if I have taken an overdose of Zipsal-40 Capsule

Take Zipsal-40 Capsule only as prescribed by the physician. Avoid exceeding the recommended dose as it could lead to an overdose. Symptoms of overdose may include drowsiness, slurred speech, uncontrolled sudden movements, uncontrollable shaking of a part of the body, and anxiety. If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

Ziprasidone is not recommended for treatment in patients with Dementia-Related Psychosis. Brief your medical history if you have any liver or kidney diseases, heart problems (coronary artery disease, irregular heartbeat), breast cancer, breathing problems (sleep apnoea), stroke, diabetes, dementia, fits, low white blood cells, obesity, and swallowing problems before starting Zipsal-40 Capsule . Please consult your doctor if you are pregnant, planning to conceive or a breastfeeding mother before using Zipsal-40 Capsule . Avoid consuming alcohol as it might lead to increased side effects like dizziness and drowsiness. Avoid driving or operating machinery as it may decrease your mental alertness, making you feel dizzy or drowsy. Zipsal-40 Capsule is not recommended for people below 18 years of age as the safety and effectiveness have not been established.

Drug-Drug Interactions

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ZiprasidoneKetoconazole
Critical
ZiprasidoneOfloxacin
Critical

Drug-Drug Interactions

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ZiprasidoneKetoconazole
Critical
How does the drug interact with Zipsal-40 Capsule:
Taking Ketoconazole with Zipsal-40 Capsule can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Zipsal-40 Capsule with Ketoconazole is not recommended, it can be taken together if prescribed by a doctor. However, consult a doctor if you experience sudden dizziness, lightheadedness, fainting, breathing difficult. Do not discontinue any medications without consulting a doctor.
ZiprasidoneOfloxacin
Critical
How does the drug interact with Zipsal-40 Capsule:
Coadministration of Ofloxacin with Zipsal-40 Capsule can increase the risk or severity of irregular heart rhythm.

How to manage the interaction:
Taking Ofloxacin with Zipsal-40 Capsule together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
ZiprasidoneClarithromycin
Critical
How does the drug interact with Zipsal-40 Capsule:
Taking Clarithromycin with Zipsal-40 Capsule can increase the risk of irregular heart rhythm.

How to manage the interaction:
Co-administration of Clarithromycin and Zipsal-40 Capsule can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
ZiprasidoneSotalol
Critical
How does the drug interact with Zipsal-40 Capsule:
Co-administration of Zipsal-40 Capsule together with sotalol can increase the risk or severity of irregular heart rhythms which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Sotalol with Zipsal-40 Capsule together is generally avoided as it can result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not discontinue any medications without consulting a doctor.
ZiprasidoneAmisulpride
Critical
How does the drug interact with Zipsal-40 Capsule:
Co-administration of Zipsal-40 Capsule with Amisulpride can increase the risk of severe irregular heart rhythm.

How to manage the interaction:
Although there is an interaction between Zipsal-40 Capsule and Amisulpride but can be taken together if prescribed by a doctor. Contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
ZiprasidoneQuinine
Critical
How does the drug interact with Zipsal-40 Capsule:
Co-administration of Quinine with Zipsal-40 Capsule can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Quinine with Zipsal-40 Capsule together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not discontinue any medications without consulting a doctor.
ZiprasidoneDoxepin
Critical
How does the drug interact with Zipsal-40 Capsule:
Taking Doxepin with Zipsal-40 Capsule can increase the risk of abnormal heart rhythm.

How to manage the interaction:
Taking Doxepin with Zipsal-40 Capsule is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
ZiprasidoneFoscarnet
Critical
How does the drug interact with Zipsal-40 Capsule:
Taking Foscarnet with Zipsal-40 Capsule can increase the risk of abnormal heart rhythm.

How to manage the interaction:
Taking Foscarnet with Zipsal-40 Capsule is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
ZiprasidoneMaprotiline
Critical
How does the drug interact with Zipsal-40 Capsule:
Taking Maprotiline with Zipsal-40 Capsule can increase the risk of abnormal heart rhythm.

How to manage the interaction:
Taking Zipsal-40 Capsule with Maprotiline is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
ZiprasidoneArsenic trioxide
Critical
How does the drug interact with Zipsal-40 Capsule:
Co-administration of Arsenic trioxide with Zipsal-40 Capsule can increase the risk of irregular heart rhythm.

How to manage the interaction:
Although there is an interaction between Zipsal-40 Capsule and Arsenic trioxide but can be taken together if prescribed by a doctor. Contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Maintain proper weight by following a healthy diet.
  • Exercise regularly as it helps in less cognitive decline and brain volume loss.
  • Avoid smoking and alcohol consumption.
  • Try to avoid stress by practising meditation or yoga.
  • Include fruits and vegetables in your diet as they contain anti-oxidants.
  • Eat nutritious food as it helps in cognitive stimulation.
  • Limit foods with high cholesterol and saturated fats.
  • Cut down on sugar, salt and processed foods.
  • Drink plenty of water.
  • Follow a healthy lifestyle as it helps in improving overall health and possibly protects the brain.

Habit Forming

No

Therapeutic Class

ANTIPSYCHOTICS

Zipsal-40 Capsule Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Unsafe

It is advised to avoid alcohol consumption while taking Zipsal-40 Capsule . Alcohol intake, along with Zipsal-40 Capsule , may cause increased dizziness and drowsiness. Please consult your doctor for more information.

bannner image

Pregnancy

Caution

Using antipsychotic drugs during the third trimester of pregnancy may cause muscle problems in newborns. Please consult your doctor before taking Zipsal-40 Capsule if you are pregnant or planning to conceive.

bannner image

Breast Feeding

Caution

It is not known if Zipsal-40 Capsule is excreted into the breast milk. Please consult your doctor before taking Zipsal-40 Capsule if you are a breastfeeding mother.

bannner image

Driving

Unsafe

Zipsal-40 Capsule may make you feel dizzy or drowsy. Do not drive if you are not mentally alert or experience any symptoms that affect your ability to drive or operate machinery.

bannner image

Liver

Caution

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns.

bannner image

Kidney

Caution

Please consult your doctor before using Zipsal-40 Capsule if you suffer from any severe kidney impairment/disease.

bannner image

Children

Unsafe

Zipsal-40 Capsule is not recommended in people below 18 years of age.

Have a query?

FAQs

Zipsal-40 Capsule is used to treat schizophrenia and manic depression (bipolar disorder).

Zipsal-40 Capsule works by balancing the chemical messengers like dopamine and serotonin located in the brain, thereby improving mood, behaviour and thoughts.

Zipsal-40 Capsule should be used with caution in the medical history of liver or kidney diseases, heart problems (coronary artery disease, irregular heartbeat), breast cancer, breathing problems (sleep apnoea), stroke, diabetes, dementia, fits, low white blood cells, obesity, and swallowing problems. Please let your doctor know if you have any other medical problems before starting Zipsal-40 Capsule .

Zipsal-40 Capsule may make you sweat less and can likely cause heart stroke. Hence, it is advised to limit activities that cause overheat like an exercise in hot weather or using hot tubs. Drink plenty of fluids and dress lightly.

Zipsal-40 Capsule may cause dizziness. It is advised to avoid getting up too fast from a sitting or lying position to make you feel dizzy.

Zipsal-40 Capsule can cause a side effect called orthostatic hypotension (sudden lowering in blood pressure leading to dizziness on standing). If you experience this, do not try to stand up suddenly or start walking, instead lie down and get up slowly only when you feel better. People taking Zipsal-40 Capsule are advised to regularly monitor their blood pressure levels to avoid such unpleasant events.

Country of origin

India
Other Info - ZIP0119

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Author Details

Veda MaddalaDoctor badge

Written By

Veda Maddala

M Pharmacy

Bayyarapu Mahesh KumarDoctor badge

Reviewed By

Bayyarapu Mahesh Kumar

M Pharmacy

Last Updated

Jan 1, 2025 | 2:48 PM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://www.slam.nhs.uk/media/18312/ziprasidone.pdf
  2. https://www.drugs.com/pregnancy/ziprasidone.html
  3. https://www.webmd.com/drugs/2/drug-20568/ziprasidone-oral/details
  4. https://www.accessdata.fda.gov/drugsatfda_docs/label/2009/020825s035,020919s02bl.pdf
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