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Zita-DM 1000 Tablet is an antidiabetic medicine used to treat Type II Diabetes. It contains Dapagliflozin (sodium-glucose cotransporter-2 inhibitors), Tenegliptin (dipeptidyl peptidase-4 inhibitor), and Metformin (biguanides), which work by increasing the amounts of certain natural substances that lower blood sugar when it is high. The common side effects of this medication are vomiting, nausea, abdominal pain, headache, frequent urination, and allergic reactions.

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Written By Dr. Lakshmithulasi Yarragunta , PharmD (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

DAPAGLIFLOZIN-10MG+METFORMIN-1000MG+TENEGLIPTIN-20MG

Manufacturer/Marketer :

Glenmark Pharmaceuticals Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Zita-DM 1000 Tablet

Zita-DM 1000 Tablet is an oral prescription medicine used to treat type 2 diabetes mellitus. It helps control high blood sugar levels in adults when diet, exercise, and other single or double-drug therapies are not enough. By keeping your blood sugar in a healthy range, it helps prevent serious long-term complications.

For the best results, you must take Zita-DM 1000 Tablet regularly and exactly as prescribed by your doctor. It is typically taken once daily, and taking it with food can help reduce the chance of an upset stomach. Combining this medicine with a balanced diet and regular exercise is essential to achieve optimal blood sugar control.

Some people may experience mild side effects like nausea, an upset stomach, or mild diarrhea. However, if you experience severe side effects such as deep, rapid breathing, severe stomach pain, or signs of a serious urinary tract infection, you must contact your doctor immediately.

Before starting Zita-DM 1000 Tablet , talk to your doctor if you have a history of kidney disease, liver damage, heart problems, or severe dehydration. Do not take this if you have type 1 diabetes, diabetic ketoacidosis, or severe kidney failure.

Drinking alcohol while taking Zita-DM 1000 Tablet can increase your risk of a rare but serious acid buildup in the blood, so it is best to avoid alcohol. Certain medicines like water pills or other blood sugar-lowering drugs can interact with it, so share your full medical list with your pharmacist. If you are pregnant, breastfeeding, or are an older adult, consult your doctor before using this medicine to ensure it is safe for you.

Uses of Zita-DM 1000 Tablet

Zita-DM 1000 Tablet is used in the treatment of Type II Diabetes Mellitus. The detailed uses of Zita-DM 1000 Tablet are as follows:

  • Type 2 Diabetes Mellitus: Zita-DM 1000 Tablet helps lower high blood sugar levels in adults whose diabetes cannot be controlled by diet, exercise, or other medicines alone.
  • Prevention of Diabetes Complications: By maintaining healthy blood sugar levels, Zita-DM 1000 Tablet helps reduce the risk of developing serious long-term issues such as kidney damage, nerve pain, blindness, and heart disease.

Key Benefits

  • Zita-DM 1000 Tablet provides stable, round-the-clock control of your blood sugar levels, helping you avoid the uncomfortable spikes and crashes that cause fatigue and irritability.
  • Because it combines three active therapies into one tablet, it simplifies your daily routine, reducing the number of pills you need to take each day.
  • By helping keep your blood sugar under control over time, this medicine may reduce the risk of long-term diabetes-related complications affecting the kidneys, eyes, nerves, and heart when used as part of a complete diabetes management plan.

Directions for Use

  • Take Zita-DM 1000 Tablet with or without food or as advised by a doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication, to ensure the safety.
  • Swallow the medicine as a whole with a glass of water.
  • Do not crush, break, or chew it.

How Zita-DM 1000 Tablet Works

Zita-DM 1000 Tablet contains three medicines that work together in different ways to help control your blood sugar: Dapagliflozin helps your kidneys remove excess sugar from your blood by passing it out through your urine. This lowers blood sugar levels and may also provide benefits for the heart and kidneys in some people with type 2 diabetes. Tenegliptin works by blocking an enzyme called DPP-4. This allows your body's natural gut hormones (called incretins) to stay active for longer. These hormones help your pancreas release more insulin only when your blood sugar rises after eating and also help reduce the release of glucagon, a hormone that raises blood sugar. Metformin mainly works by reducing the amount of sugar made by your liver. It also helps your body's cells respond better to insulin so they can use sugar more effectively, which helps lower blood sugar levels. Together, these three medicines control blood sugar through different pathways, helping improve overall diabetes management when combined with a healthy diet, regular exercise, and other lifestyle measures.
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Alcohol

Unsafe

Alcohol increases the impact of metformin on lactate metabolism. Hence, you should not consume excessive amounts of alcohol, either temporarily or permanently, while taking Zita-DM 1000 Tablet .

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Pregnancy

Caution

There are no adequate studies on the effect of Zita-DM 1000 Tablet in pregnancy. If you are pregnant or planning pregnancy, inform your doctor before taking Zita-DM 1000 Tablet .

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Breast Feeding

Caution

Zita-DM 1000 Tablet is generally not recommended in breastfeeding. Hence, if you are breastfeeding, inform your doctor before using Zita-DM 1000 Tablet .

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Driving

Consult your doctor

Zita-DM 1000 Tablet usually does not affect your ability to drive or operate machinery.

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Liver

Caution

Use Zita-DM 1000 Tablet cautiously, as lactic acidosis can occur due to metformin accumulation. The risk increases with hepatic insufficiency. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Kidney

Caution

Renal impairment also increases the risk of lactic acidosis. Hence, Zita-DM 1000 Tablet should be used cautiously if you have kidney problems. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Children

Unsafe

Zita-DM 1000 Tablet is not recommended for children below 18 years as the safety and effectiveness were not established.

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Heart

Consult your doctor

Please consult your doctor if you have any concerns regarding the usage of Zita-DM 1000 Tablet in patients with heart problems.

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Geriatrics

Caution

Elderly patients may require caution and dose adjustments, as Zita-DM 1000 Tablet may increase the risk of side effects.

What if I have taken an overdose of Zita-DM 1000 Tablet

If you take more than your prescribed dose, seek immediate emergency medical care or contact a poison control center. An overdose can cause dangerously low blood sugar or a serious buildup of acid in your blood.

Diet & Lifestyle Advise

  • Focus on complex carbohydrates like whole grains, vegetables, and lean proteins, while avoiding sugary drinks, refined sweets, and processed snacks.
  • Engage in at least 150 minutes of moderate physical activity, such as brisk walking, weekly to help your body use insulin more effectively.
  • Monitor your blood sugar levels regularly as advised by your healthcare team to track how your diet and lifestyle adjustments are working.
  • Stay well-hydrated throughout the day by drinking plenty of water, which helps your kidneys naturally flush out excess sugar.
  • Take care of your feet by washing them daily, checking for any cuts or sores, and wearing comfortable, well-fitting shoes.
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Have a query?

How Soon It Starts Working

The time required for Zita-DM 1000 Tablet to start to work: The time required for Zita-DM 1000 Tablet to show its action is unknown. The time for which the effects of Zita-DM 1000 Tablet last: The duration of action for Zita-DM 1000 Tablet is unknown.

What if you forget to take Zita-DM 1000 Tablet

Take the missed dose as soon as you remember with food. However, if it is almost time for your next scheduled dose, skip the missed one and return to your regular timing. Do not take two doses at the same time to make up for a missed one.

Storage

• Store Zita-DM 1000 Tablet at room temperature, ideally between 20°C and 25°C (68°F to 77°F).

Drug Warnings

  • Check your blood sugar immediately if you feel shaky, sweaty, dizzy, or confused, as these can be signs of low blood sugar.
  • Drink plenty of water daily to prevent dehydration, which can increase the risk of rare but serious kidney or blood acid complications.
  • Always carry a fast-acting sugar source, such as fruit juice, hard candy, or glucose tablets, in case your blood sugar drops too low.
  • Tell any surgeon or dentist that you are taking Zita-DM 1000 Tablet before you undergo any medical procedures, as you may need to stop taking it temporarily.
  • Inspect your tablets before taking them; do not use them if the packaging is damaged or if the tablets appear discolored or broken.
  • If you are scheduled for major surgery, prolonged fasting, or certain imaging tests using iodinated contrast dye, your doctor may advise you to temporarily stop this medicine and restart it when it is safe.

verifiedApollotooltip

  • Taking Zita-DM 1000 Tablet with other blood-sugar-lowering medicines (such as insulin or sulfonylureas) may increase the risk of low blood sugar.
  • Water pills (diuretics) may increase the risk of dehydration and kidney strain when taken alongside this medicine.
  • Certain heart medications (like beta-blockers) can mask the warning signs of low blood sugar, such as a rapid heart rate.

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verifiedApollotooltip
  • Avoid heavy alcohol consumption, as it significantly raises the risk of a dangerous buildup of acid in your blood (lactic acidosis) and can cause unpredictable blood sugar levels.

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Habit Forming

No

Therapeutic Class

[ANTIDIABETICS]

FAQs

Zita-DM 1000 Tablet is used to treat Type II Diabetes Mellitus.
Zita-DM 1000 Tablet is a combination medicine containing Dapagliflozin, which helps remove excess sugar from the body via urine; Tenegliptin, which enhances glucose-mediated insulin secretion, thereby reducing fasting and post-prandial blood sugar concentrations; and Metformin, which helps reduce sugar production by cells in the liver and delays sugar absorption from the intestines.
If you forget to take Zita-DM 1000 Tablet , take it as soon as you remember. However, if it's time for the next dose, avoid taking it and do not double dose to make up for the missed dose. Taking an overdose might cause your sugar level to fall rapidly.
It is highly recommended to take Zita-DM 1000 Tablet with food. Taking it with a meal helps prevent stomach upset, nausea, and indigestion. Talk to your doctor or pharmacist if you struggle with nausea.
Dizziness can be a sign of low blood sugar or dehydration. Sit or lie down immediately, drink some water, or consume a fast-acting sugar source if your blood sugar is low. If the dizziness continues, talk to your doctor.
No, you should avoid drinking alcohol while taking Zita-DM 1000 Tablet . Alcohol increases the risk of a rare but life-threatening condition called lactic acidosis (acid buildup in the blood) and can cause dangerous drops in blood sugar. Talk to your doctor for more guidance.
This medicine starts lowering blood sugar soon after you begin taking it. However, noticeable improvements in your overall diabetes control, including your HbA1c (average blood sugar over the past 2–3 months), usually take about 8–12 weeks of regular treatment. Continue taking the medicine as prescribed and attend your scheduled follow-up appointments so your doctor can monitor your progress.
Some components of Zita-DM 1000 Tablet may lead to modest weight loss by helping your body flush out excess sugar and improving insulin use. However, it is not a weight-loss drug and should only be used to manage type 2 diabetes. Talk to your doctor for personalized advice.
Because of how this medicine works, you may have a higher risk of urinary tract infections. Watch for symptoms like a strong burning feeling when you urinate, needing to urinate more often, cloudy urine, pelvic pain, or a fever. If you notice these signs, contact your doctor right away.
No, you should not stop taking Zita-DM 1000 Tablet without consulting your healthcare provider. Your blood sugar levels are normal because the medicine is working. Stopping it suddenly can cause your blood sugar to spike again. Talk to your doctor before making any changes.
This medicine helps your body remove sugar through your urine, which can make you lose more fluids. It is very important to drink plenty of water throughout the day to stay hydrated and protect your kidneys, especially in hot weather or if you are active. Talk to your doctor if you experience severe vomiting or diarrhea.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

Glenmark Pharmaceuticals Limited, B/2, Mahalaxmi Chambers, 22, Bhulabhai Desai Road, Mumbai 400 026.
Other Info - ZIT0229
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