Zofer 4 mg Injection 2 ml
MRP ₹25
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About Zofer 4 mg Injection 2 ml
Zofer 4 mg Injection 2 ml is used to prevent and treat nausea and vomiting during chemotherapy. Nausea is an uneasy feeling in which a person feels an urge to vomit, while vomiting is the natural response of the body to expel the stomach contents from the mouth forcefully.
Zofer 4 mg Injection 2 ml contains Ondansetron, which works by blocking the action of a chemical in the body (serotonin) responsible for causing nausea and vomiting.
In some cases, Zofer 4 mg Injection 2 ml may cause headache, constipation, a feeling of warmth or flushing, redness, and irritation at the site of injection. If the side effects persist or worsen, please consult your doctor.
If you are allergic to Zofer 4 mg Injection 2 ml or any other medicines, please tell your doctor. It should be given to children only in doses advised by the doctor based on the child’s body weight or body surface area. If you are pregnant or breastfeeding, you must inform your doctor before taking Zofer 4 mg Injection 2 ml.
Uses of Zofer 4 mg Injection 2 ml
Zofer 4 mg Injection 2 ml is used to prevent and treat nausea and vomiting caused by various medical conditions. The detailed uses of Zofer 4 mg Injection 2 ml are as follows:
- Chemotherapy-induced nausea and vomiting (CINV) : Zofer 4 mg Injection 2 ml is used in adults and children to prevent and manage nausea and vomiting caused by cancer chemotherapy.
- Post-operative nausea and vomiting (PONV): Zofer 4 mg Injection 2 ml helps prevent and treat nausea and vomiting that may occur after surgery.
- Radiotherapy-induced nausea and vomiting: In adults receiving radiation treatment for cancer, Zofer 4 mg Injection 2 ml is used to reduce or prevent nausea and vomiting associated with therapy.
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Directions for Use
- Follow your doctor’s instructions on the dosage and timing of this medication to ensure safe and effective use.
- Zofer 4 mg Injection 2 ml will be administered by the doctor.
- Do not self-administer.
Key Benefits
- Zofer 4 mg Injection 2 ml contains Ondansetron that blocks the action of serotonin, a chemical that stimulates the vomiting centre (chemoreceptor trigger zone – CTZ) located in the brain.
- Thus, it prevents nausea and vomiting caused by chemotherapy in adults and children, as well as after surgery.
- Additionally, Zofer 4 mg Injection 2 ml can be used to prevent nausea and vomiting caused by radiotherapy for cancer in adults.
How Zofer 4 mg Injection 2 ml Works
Storage
- Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
- Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
- Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
- Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
- Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
- Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
- Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
- Hydrate your body: Drink enough water to prevent dehydration and headaches.
- Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
- Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
- Take rest: lie down in a quiet, dark environment.
- Cold or warm compresses can help reduce tension.
- Stay Upright: Maintain good posture to keep symptoms from getting worse.
- To treat headaches naturally, try acupuncture or massage therapy.
- Over-the-counter pain relievers include acetaminophen and ibuprofen.
- Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
- Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
- Frequent Headaches: If you get reoccurring headaches, consult your doctor.
- Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
- Drink plenty of fluids to stay hydrated and replace the lost electrolytes.
- Eat small, frequent meals of bland foods like crackers, toast, or plain rice.
- Avoid heavy or fatty foods that can worsen nausea.
- Use relaxation techniques like deep breathing or meditation to manage stress and anxiety.
- Minimize exposure to strong smells or odors that can trigger nausea.
- Ensure good airflow in the room by keeping it well-ventilated and maintaining a comfortable temperature.
- Inform your doctor immediately if you experience a fever after starting a new medication.
- Your doctor may adjust your medication regimen or dosage as needed to minimize fever symptoms.
- Monitor your body temperature to monitor fever progression.
- Drink plenty of fluids, such as water or electrolyte-rich beverages, to help your body regulate temperature.
- Get plenty of rest and engage in relaxation techniques, such as deep breathing or meditation, to help manage fever symptoms.
- Under the guidance of your doctor, consider taking medication, such as acetaminophen or ibuprofen, to help reduce fever.
- If your fever is extremely high (over 103°F), or if you experience severe symptoms such as confusion, seizures, or difficulty breathing, seek immediate medical attention.
What if I have taken an overdose of Zofer 4 mg Injection 2 ml
Drug Warnings
- If you are allergic to Ondansetron, Palanosetron, Granisetron, or any other medicines, please tell your doctor.
- Zofer 4 mg Injection 2 ml should be given to children only in doses as advised by the doctor based on the child’s body weight or body surface area.
- Zofer 4 mg Injection 2 ml should be used during pregnancy or breastfeeding after consultation with a doctor.
- If you have problems with levels of sodium, magnesium, and potassium salts in your blood, inform your doctor before taking Zofer 4 mg Injection 2 ml.
Drug-Drug Interactions
Drug-Drug Interactions
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Taking Zofer 4 mg Injection 2 ml with Ziprasidone can increase the risk of abnormal heart rhythm.
How to manage the interaction:
Taking Zofer 4 mg Injection 2 ml with Ziprasidone is not recommended, but it can be taken together if prescribed by a doctor. However, consult a doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
Taking Zofer 4 mg Injection 2 ml with lithium can increase the risk of serotonin syndrome a condition in which a chemical called serotonin builds up in body).
How to manage the interaction:
Although taking Zofer 4 mg Injection 2 ml along with lithium can result in an interaction but can be taken together if prescribed by a doctor. However, if you have sudden dizziness, lightheadedness, fainting, confusion, hallucination, fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles, or stiffness, incoordination, stomach cramps, nausea, vomiting, and loose stools, or fast or rapid heartbeats during therapy, consult a doctor. Do not stop using any medications without talking to a doctor.
Taking Zofer 4 mg Injection 2 ml with Iloperidone increases the risk of an abnormal heart rhythm.
How to manage the interaction:
Co-administration of Zofer 4 mg Injection 2 ml along with Iloperidone can result in an interaction, it can be taken if a doctor has advised it. However, if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, consult a doctor. Do not discontinue any medications without a doctor's advice.
Taking Zofer 4 mg Injection 2 ml with vandetanib increases the risk of an abnormal heart rhythm.
How to manage the interaction:
Although taking Zofer 4 mg Injection 2 ml along with vandetanib can result in an interaction, it can be taken if a doctor has advised it. However, consult a doctor if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat. Do not discontinue any medications without a doctor's advice.
Taking Zofer 4 mg Injection 2 ml with escitalopram may increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increases in your body).
How to manage the interaction:
Co-administration of Zofer 4 mg Injection 2 ml along with escitalopram can possibly result in an interaction, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucinations (seeing and hearing things that do not exist), fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting your doctor.
Taking Zofer 4 mg Injection 2 ml with anagrelide increases the risk of an abnormal heart rhythm.
How to manage the interaction:
Co-administration of Zofer 4 mg Injection 2 ml alongside anagrelide can result in an interaction, it can be taken if a doctor has advised it. However, if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, get medical help immediately. Do not discontinue any medications without a doctor's advice.
When Zofer 4 mg Injection 2 ml, is taken with furazolidone it can cause serotonin syndrome. (a condition in which a chemical called serotonin builds up in your body).
How to manage the interaction:
Co-administration of Zofer 4 mg Injection 2 ml along with furazolidone can lead to an interaction, it can be taken if recommended by a doctor. However, if you experience symptoms such as confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, a shaking sensation, incoordination, stomach cramp, nausea, vomiting, and diarrhea, see a doctor. Do not discontinue any medications without a doctor's advice.
Taking Zofer 4 mg Injection 2 ml with methadone increases the risk of an abnormal heart rhythm.
How to manage the interaction:
Co-administration of Zofer 4 mg Injection 2 ml along with methadone can result in an interaction, it can be taken if a doctor has advised it. However, if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, consult a doctor. Do not discontinue any medications without a doctor's advice.
Taking Zofer 4 mg Injection 2 ml with nilotinib increases the risk of an abnormal heart rhythm.
How to manage the interaction:
Co-administration of Zofer 4 mg Injection 2 ml along with nilotinib can result in an interaction, it can be taken if a doctor has advised it. However, consult a doctor if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat. Do not discontinue any medications without a doctor's advice.
Taking Zofer 4 mg Injection 2 ml with crizotinib increases the risk of an abnormal heart rhythm.
How to manage the interaction:
Although taking Zofer 4 mg Injection 2 ml along with crizotinib can result in an interaction, it can be taken if a doctor has advised it. However, if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, consult a doctor. Do not discontinue any medications without a doctor's advice.
Drug-Food Interactions
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Diet & Lifestyle Advise
- Eat a healthy and low-fat diet, especially in small portions, as it will be easy to digest. Avoid eating overly sweet food and include more salty food, especially if you have been vomiting.
- Drink any other liquid at least 30 minutes after eating food.
- If the smell of food makes you feel sick (vomit), do not cook food as it may worsen your condition. Let someone else do the cooking or use prepared food from the freezer.
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Alcohol
Safe if prescribed
Avoid consuming alcohol while taking Zofer 4 mg Injection 2 ml as this medicine can interact with alcohol and may worsen the side effects.
Pregnancy
Consult your doctor
If you are pregnant, inform your doctor before taking Zofer 4 mg Injection 2 ml. Your doctor will weigh the benefits and risks before prescribing this medicine.
Breast Feeding
Consult your doctor
If you are a nursing mother, inform your doctor before taking Zofer 4 mg Injection 2 ml. Your doctor will weigh the benefits and risks before prescribing this medicine.
Driving
Safe if prescribed
Zofer 4 mg Injection 2 ml usually does not affect your driving ability. However, do not drive if you feel any discomfort.
Liver
Consult your doctor
Take Zofer 4 mg Injection 2 ml with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.
Kidney
Consult your doctor
Zofer 4 mg Injection 2 ml may be safe to use in patients with kidney problems if prescribed by a doctor.
Children
Safe if prescribed
Zofer 4 mg Injection 2 ml should be used in children only in doses advised by the doctor based on child’s body weight or body surface area.
Heart
Zofer 4 mg Injection 2 ml may be used in heart patients but requires caution due to risk of QT prolongation. ECG monitoring is advised to prevent serious arrhythmias, especially in those with existing cardiac conditions.
Geriatrics
Consult your doctor
Zofer 4 mg Injection 2 ml can be used in geriatric patients, but with caution. Older adults may be more sensitive to side effects like QT prolongation, so ECG monitoring is often recommended during treatment.
FAQs
Zofer 4 mg Injection 2 ml belongs to a class of drugs called antiemetics used to prevent nausea and vomiting during chemotherapy.
Zofer 4 mg Injection 2 ml works by blocking the action of serotonin, a chemical that stimulates the vomiting center (chemoreceptor trigger zone – CTZ) located in the brain. Thus, it prevents nausea and vomiting.
You are not recommended to take erythromycin with Zofer 4 mg Injection 2 ml as it may increase the risk of severe irregular heart rhythm. However, please consult your doctor before taking other medicines with Zofer 4 mg Injection 2 ml.
Zofer 4 mg Injection 2 ml may cause constipation as a side effect. It is not necessary for everyone taking Zofer 4 mg Injection 2 ml to experience this side effect. However, if the condition persists or worsens, please consult a doctor.
Zofer 4 mg Injection 2 ml should be used with caution in patients suffering from liver problems. However, inform your doctor if you have any liver problems before taking Zofer 4 mg Injection 2 ml so that the dose may be adjusted appropriately.
Yes, Zofer 4 mg Injection 2 ml may be used to prevent nausea and vomiting after surgery. Zofer 4 mg Injection 2 ml blocks serotonin (a chemical) action which is responsible for causing nausea and vomiting.
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