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  1. Home
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  3. Zolfresh 10 mg Tablet 15's

Zolfresh 10 mg Tablet 15's, Pack of 15 TABLETS
Zolfresh 10 mg Tablet 15's, Pack of 15 TABLETS
Zolfresh 10 mg Tablet 15's, Pack of 15 TABLETS
Zolfresh 10 mg Tablet 15's, Pack of 15 TABLETS
Zolfresh 10 mg Tablet 15's, Pack of 15 TABLETS
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Composition :

ZOLPIDEM-10MG

Manufacturer/Marketer :

Abbott India Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

NPPA :

Regulated

About Zolfresh 10 mg Tablet

Zolfresh 10 mg Tablet belongs to a class of drugs called 'sedative-hypnotics' primarily used in the short-term treatment of insomnia. Insomnia is a disorder of sleep that causes difficulty in falling asleep or staying asleep. It may be acute (short-term) or chronic (long-term) in nature due to various complications like stress, anxiety, and breathing problems.

Zolfresh 10 mg Tablet contains Zolpidem which works by increasing the activity of GABA, which is a chemical messenger in the brain acting as a natural nerve-calming agent, thereby inducing sleep. Thus, Zolfresh 10 mg Tablet relaxes muscles, reduces anxiety, and helps to fall asleep.

Take Zolfresh 10 mg Tablet as prescribed. Your doctor will advise you how often you take Zolfresh 10 mg Tablet based on your medical condition. Some people may experience dizziness, diarrhoea, drowsiness, headache, nausea, vomiting, nose or throat infections, tiredness, stomach pain, double vision, and back pain. Most of these side effects of Zolfresh 10 mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are known to be allergic to Zolfresh 10 mg Tablet or any other medicines, please tell your doctor. If you notice that the effect of tablets is not as well as at the beginning of the treatment, please consult a doctor as you might have developed tolerance to Zolfresh 10 mg Tablet and dose adjustment may be required. If you are pregnant or breastfeeding, it is advised to consult a doctor before using Zolfresh 10 mg Tablet . If you have kidney, liver, or breathing problems, severe muscle weakness, sleep apnoea (a serious condition where breathing stops and repeatedly starts in sleep), and if you have a history of depression or mental illness, please inform your doctor before taking Zolfresh 10 mg Tablet .

Directions for Use

• Take Zolfresh 10 mg Tablet on empty stomach for effective results or as advised by the doctor. • It is advised to take Zolfresh 10 mg Tablet once daily before bedtime; however, follow your doctor’s recommendation regarding the dosage and duration.• Swallow Zolfresh 10 mg Tablet as a whole with a glass of water. • Do not crush, chew or break it.

Medicinal Benefits

Zolfresh 10 mg Tablet is a sleeping pill used in the short-term treatment of insomnia (difficulty in falling or staying asleep). Zolfresh 10 mg Tablet increases the activity of GABA (a chemical messenger in brain that acts as natural nerve-calming agent) that is involved in inducing sleep. Thus, Zolfresh 10 mg Tablet relaxes muscles, reduces anxiety and helps to fall asleep. Appropriate life style changes are recommended along with Zolfresh 10 mg Tablet to improve the quality of sleep.

How Zolfresh 10 mg Tablet Works

Zolfresh 10 mg Tablet contains Zolpidem which works by increasing the activity of GABA, which is a chemical messenger in the brain acting as a natural nerve-calming agent, thereby inducing sleep. Thus, Zolfresh 10 mg Tablet relaxes muscles, reduces anxiety, and helps to fall asleep.

Storage

Store in a cool and dry place away from sunlight
Side effects of Zolfresh 10 mg Tablet
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Avoid driving or operating machinery or activities that require high focus until you know how the medication affects you.
  • Maintain a fixed sleeping schedule, create a relaxing bedtime routine and ensure your sleeping space is comfortable to maximize your sleep quality.
  • Limit alcohol and caffeine as these may worsen drowsiness and disturb sleep patterns.
  • Drink plenty of water as it helps with alertness and keeps you hydrated and for overall well-being.
  • Moderate physical activity can improve energy levels, but avoid intense workouts right before bedtime.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • Get enough sleep. Maintain a regular sleep cycle.
  • Eat a healthy diet and exercise regularly.
  • Manage stress with yoga or meditation.
  • Limit alcohol and caffeine.
  • Avoid driving or operating machinery unless you are alert.
  • Uncoordinated muscle movements need immediate medical attention.
  • Observe your movements and try to understand and control the particular movement.
  • Regularly do strengthening exercises to improve blood flow throughout the body and avoid involuntary movements.
  • Implement massage techniques to enhance blood flow to organs.
  • Take a balanced diet and quit smoking.
  • Practice yoga and meditation to improve thought processes and reduce uncontrolled and involuntary movements.
  • Hallucination is a major psychotic disorder that needs immediate medical attention.
  • Acknowledge your experience and put effort to control hallucinations. You can share what is being seen with a therapist to know whether they are real or imaginary.
  • Avoid smoking and alcohol intake as it can worsen the condition and increase your imagination.
  • Practice meditation and yoga to avoid anxiety, which can be one of the leading causes of hallucinations.
  • Talk to your dietician and consume food that can improve your mental health.

What if I have taken an overdose of Zolfresh 10 mg Tablet

Do not take more than the prescribed dose of Zolfresh 10 mg Tablet as it may cause overdose. The symptoms of overdose include confusion, severe drowsiness, fainting, shallow breathing, lightheadedness or coma. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

If you notice that the tablets are not working as well as they did at the beginning of the treatment, please consult a doctor as you might have developed tolerance to Zolfresh 10 mg Tablet and dose adjustment may be required. Zolfresh 10 mg Tablet is a category C pregnancy drug and is not recommended for use during pregnancy as it may cause adverse effects on the baby after birth. If you are a breastfeeding mother, it is advised to consult a doctor before using Zolfresh 10 mg Tablet . If you have kidney, liver, or breathing problems, severe muscle weakness, sleep apnoea (a severe condition in which breathing stops and starts repeatedly in sleep), and if you have a history of depression or mental illness, please inform your doctor before taking Zolfresh 10 mg Tablet . Maintain a time gap of a minimum of 8 hours between taking Zolfresh 10 mg Tablet and driving to reduce the risk of increased adverse effects.

Drug-Drug Interactions

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ZolpidemSodium oxybate
Critical
ZolpidemSufentanil
Severe

Drug-Drug Interactions

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ZolpidemSodium oxybate
Critical
How does the drug interact with Zolfresh 10 mg Tablet:
Using sodium oxybate together with Zolfresh 10 mg Tablet can significantly increase the risk of severity of low blood pressure, breathing difficulties, fainting and unconsciousness.

How to manage the interaction:
Taking Sodium oxybate with Zolfresh 10 mg Tablet is generally avoided as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you notice any symptoms of headache, dizziness, lightheadedness, fainting, and/or changes in pulse or heart rate consult a doctor immediately. You should refrain from operating any dangerous machinery or driving a car. Do not stop using any medications without talking to a doctor.
ZolpidemSufentanil
Severe
How does the drug interact with Zolfresh 10 mg Tablet:
Using Zolfresh 10 mg Tablet together with Sufentanil can cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although taking Sufentanil and Zolfresh 10 mg Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience dizziness, drowsiness, difficulty concentrating, impairment in judgment, or reaction speed, consult a doctor. You should refrain from using dangerous machinery or driving a car. Do not discontinue any medications without consulting a doctor.
ZolpidemKetamine
Severe
How does the drug interact with Zolfresh 10 mg Tablet:
Taking Zolfresh 10 mg Tablet with Ketamine increases the effects of Zolfresh 10 mg Tablet. This can increase the risk or severity of side effects.

How to manage the interaction:
Although taking Ketamine and Zolfresh 10 mg Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience dizziness, drowsiness, difficulty concentrating, impairment in judgment, or reaction speed, consult a doctor. You should wait until the following day to operate any dangerous machinery or drive a car. Do not discontinue any medications without consulting a doctor.
ZolpidemCodeine
Severe
How does the drug interact with Zolfresh 10 mg Tablet:
Using Zolfresh 10 mg Tablet together with Codeine can cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although taking codeine and Zolfresh 10 mg Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience dizziness, drowsiness, difficulty concentrating, impairment in judgment, or reaction speed, consult a doctor. Do not discontinue any medications without consulting a doctor.
ZolpidemAlfentanil
Severe
How does the drug interact with Zolfresh 10 mg Tablet:
Using Zolfresh 10 mg Tablet together with Alfentanil may increase the risk of central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although taking Alfentanil and Zolfresh 10 mg Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience dizziness, drowsiness, difficulty concentrating, or impairment in judgment consult a doctor. Do not stop using any medications without a doctor's advice.
ZolpidemOxycodone
Severe
How does the drug interact with Zolfresh 10 mg Tablet:
Using Zolfresh 10 mg Tablet together with Oxycodone can cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although taking Oxycodone and Zolfresh 10 mg Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience dizziness, drowsiness, difficulty concentrating, impairment in judgment, or reaction speed, consult a doctor. You should refrain from using dangerous machinery or driving a car. Do not discontinue any medications without consulting a doctor.
ZolpidemTramadol
Severe
How does the drug interact with Zolfresh 10 mg Tablet:
Using Zolfresh 10 mg Tablet together with Tramadol can cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although taking Tramadol and Zolfresh 10 mg Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience dizziness, drowsiness, difficulty concentrating, impairment in judgment, or reaction speed, consult a doctor. You should refrain from using dangerous machinery or driving a car. Do not discontinue any medications without consulting a doctor.
ZolpidemPindolol
Severe
How does the drug interact with Zolfresh 10 mg Tablet:
Taking Zolfresh 10 mg Tablet with Pindolol may increase the risk of low blood pressure.

How to manage the interaction:
Although taking Pindolol and Zolfresh 10 mg Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience headache, dizziness, lightheadedness, fainting, and/or changes in pulse or heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.
ZolpidemMorphine
Severe
How does the drug interact with Zolfresh 10 mg Tablet:
Using Zolfresh 10 mg Tablet together with Morphine can cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although taking Morphine and Zolfresh 10 mg Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience dizziness, drowsiness, difficulty concentrating, impairment in judgment, or reaction speed, consult a doctor. You should refrain from using dangerous machinery or driving a car. Do not discontinue any medications without consulting a doctor.
ZolpidemEsketamine
Severe
How does the drug interact with Zolfresh 10 mg Tablet:
Taking Zolfresh 10 mg Tablet with Esketamine increases the effects of Zolfresh 10 mg Tablet. This can increase the risk or severity of side effects.

How to manage the interaction:
Although taking Esketamine and Zolfresh 10 mg Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience dizziness, drowsiness, difficulty concentrating, impairment in judgment, or reaction speed, consult a doctor. You should wait until the following day to operate any dangerous machinery or drive a car. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Do regular exercise during day time.

  • Do not take nap during day time. Set regular timings to go to bed and wake up.

  • Relax yourself at least 1 hour before bedtime by taking a bath with warm water, listening to music or reading a book.

  • Make the bedroom dark and quiet and ensure that your pillows and mattresses are comfortable.

  • Avoid watching tv, using mobiles or laptops just before bedtime.

  • Limit caffeine intake including tea, coffee, hot chocolate, cola and energy drinks as it may reduce the effectiveness of Zolfresh 10 mg Tablet .

  • Avoid consumption of alcohol as it may increase risk of psychomotor impairment (slowdown of thought process and reduced physical movements), dependence, sleep walking or sleep driving.

Habit Forming

Yes

Therapeutic Class

SEDATIVE-HYPNOTIC DRUGS

Zolfresh 10 mg Tablet Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Unsafe

Avoid consumption of alcohol with Zolfresh 10 mg Tablet as it may increase the risk of dependence, psychomotor impairment (slowdown of thought process and reduced physical movements), sleep walking or sleep driving.

bannner image

Pregnancy

Unsafe

Zolfresh 10 mg Tablet is a Category C pregnancy drug and is not recommended for use during pregnancy as it may cause adverse effects in baby after birth.

bannner image

Breast Feeding

Unsafe

Avoid breastfeeding while taking Zolfresh 10 mg Tablet as it may be excreted in breast milk.

bannner image

Driving

Unsafe

You may experience dizziness, drowsiness, confusion, decreased alertness, blurred or double vision especially the day after taking Zolfresh 10 mg Tablet . Therefore, avoid driving if you feel drowsy or dizzy after taking Zolfresh 10 mg Tablet .

bannner image

Liver

Caution

Take Zolfresh 10 mg Tablet with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required. Zolfresh 10 mg Tablet is not recommended for severe liver disease patients.

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Kidney

Caution

Take Zolfresh 10 mg Tablet with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

bannner image

Children

Unsafe

Zolfresh 10 mg Tablet is not recommended for children below 18 years of age.

Have a query?

FAQs

Zolfresh 10 mg Tablet is used in the short-term treatment of insomnia.

No, you are not recommended to take Zolfresh 10 mg Tablet with hydrocodone or other opioid pain killers such as oxycodone, naloxone and tramadol as co-administration of these medicines with Zolfresh 10 mg Tablet may increase the risk of difficulty in breathing, drowsiness, coma and even death. However, before using Zolfresh 10 mg Tablet with any other medicines, you are advised to contact your doctor so that the dose may adjusted to use safely.

You are recommended to take Zolfresh 10 mg Tablet just before bedtime as it helps to sleep quickly and improve the quality of sleep. If you forget to take Zolfresh 10 mg Tablet at night, do not take it in the day time as it may cause drowsiness, confusion and dizziness.

No, Zolfresh 10 mg Tablet is not recommended for depression patients as it may worsen the condition and increase self-harming or suicidal thoughts. Therefore, if you are suffering from depression or have history of depression, please inform your doctor before taking Zolfresh 10 mg Tablet .

No, Zolfresh 10 mg Tablet is not recommended for use during pregnancy especially in the third trimester and during delivery as it may cause adverse effects such as breathing problems, low body temperature, floppy muscle and withdrawal symptoms in baby after birth due to physical dependence.

Yes, Zolfresh 10 mg Tablet may cause dependence (mental and physical effects caused due to compulsion of taking Zolfresh 10 mg Tablet ) if used in high doses and for prolonged time. This risk of dependency on Zolfresh 10 mg Tablet increases in patients who have a history of drug or alcohol abuse.

Zolfresh 10 mg Tablet helps you sleep better by increasing the activity of a chemical in your brain called GABA (Gamma-aminobutyric acid). This chemical calms your nerves and makes you feel relaxed, which helps you fall asleep. It also relaxes your muscles and reduces feelings of anxiety.

The common side effects of Zolfresh 10 mg Tablet include dizziness, diarrhoea, drowsiness, headache, nausea, vomiting, nose or throat infections, tiredness, stomach pain, double vision, and back pain. Most of these side effects are mild and usually resolve on their own. However, if the side effects persist or worsen, please consult your doctor.

Zolfresh 10 mg Tablet can cause sedation (state of sleepiness) and relaxation. Some people might misuse it in an attempt to get high from its sedative effects, so it is important to take Zolfresh 10 mg Tablet only as prescribed by your doctor.

Yes, Zolfresh 10 mg Tablet can be abused, especially if taken in higher doses or without a prescription from your doctor. This is more commonly seen in people with a history of drug abuse and alcohol consumption. Therefore, Zolfresh 10 mg Tablet should be taken only as prescribed by the doctor.

While there might not be direct drug-drug interactions between Zolfresh 10 mg Tablet and prednisone, both can affect your central nervous system. Please consult your doctor before taking Zolfresh 10 mg Tablet with prednisone.

Zolfresh 10 mg Tablet is mainly used to treat insomnia (difficulty falling asleep) and isn’t usually prescribed for anxiety (feelings of fear and uneasiness). While Zolfresh 10 mg Tablet can have a calming effect that might temporarily ease anxiety, it’s not considered a suitable long-term solution for anxiety disorders. Consult the doctor for appropriate treatment.

The symptoms of Zolfresh 10 mg Tablet overdose include confusion, somnolence (drowsiness), problems with breathing or heart function, and in severe cases, coma (a prolonged loss of consciousness). If you take too much Zolfresh 10 mg Tablet , call your doctor right away or seek emergency treatment.

You should avoid drinking alcohol while taking Zolfresh 10 mg Tablet , as it may increase the risk of psychomotor impairment (slowdown of thought processes and reduced physical movements), dependence, sleepwalking, or sleep driving. Avoid the intake of caffeine and St John’s wort (herbal medicine for treating depression), as they can make the medication less effective. If you feel dizzy, drowsy, confused, or have blurred vision after taking Zolfresh 10 mg Tablet , please avoid driving or using machines.

You should not take Zolfresh 10 mg Tablet if you are allergic to any of its ingredients. Zolfresh 10 mg Tablet is classified as a Category C pregnancy drug and is not recommended for use during pregnancy. If you are a breastfeeding mother, please avoid taking Zolfresh 10 mg Tablet , as it may be excreted in breast milk. If you have kidney or liver problems, breathing issues, severe muscle weakness, sleep apnea (a condition in which breathing stops and starts repeatedly during sleep), or a history of depression or mental illness, please consult your doctor before taking Zolfresh 10 mg Tablet .

No, you should not take Zolfresh 10 mg Tablet with food or immediately after a meal, as doing so may reduce its effectiveness. It will work faster if you take Zolfresh 10 mg Tablet on an empty stomach.

Zolfresh 10 mg Tablet should be taken as prescribed by a healthcare provider. It should only be used for a short term (usually 2-4 weeks) to treat insomnia (difficulty falling asleep) because your body gets used to this medicine quickly, which may lead to dependence (addiction to the drug).

Yes, Zolfresh 10 mg Tablet can cause dry mouth as a common side effect. This occurs because it affects neurotransmitters in the brain that influence saliva production. Regarding weight, Zolfresh 10 mg Tablet is not directly linked to significant weight gain or loss, but some people may experience changes in appetite that could indirectly affect their weight. If you have concerns about these side effects, discuss them with your doctor.

Zolfresh 10 mg Tablet generally starts working within 30 minutes after taking it. It is usually recommended to take it right before you plan to sleep.

Do not stop taking Zolfresh 10 mg Tablet without consulting your doctor, especially if you have taken it for longer than two weeks. If you suddenly stop taking Zolfresh 10 mg Tablet , you may experience withdrawal symptoms such as shakiness, lightheadedness, stomach and muscle cramps, nausea, vomiting, sweating, tiredness, uncontrollable crying, nervousness, panic attacks, difficulty falling asleep or staying asleep, uncontrollable shaking of a part of your body, and, rarely, seizures. The doctor will reduce the dose gradually to prevent withdrawal symptoms.

To improve your sleep without medication, establish a consistent sleep schedule by going to bed and waking up at the same time each day. Create a relaxing bedtime routine, limit screen time before sleep, and make sure your sleep environment is dark, cool, and quiet. Regular exercise during the day can also help promote better sleep. Avoid caffeine, cigarettes, alcohol, heavy meals, and exercise for a few hours before bedtime.

Insomnia is a disorder of sleep associated with problems in falling asleep or staying asleep. It may be acute (short-term) or chronic (long-term) in nature. Acute insomnia may last from one night to a few weeks and occurs due to stress or changes in life. Chronic insomnia may last from more than 3 nights per week to more than 3 months.

Insomnia is mostly caused by depression, stress, anxiety, jet lag, shift work, uncomfortable sleeping conditions, chronic illness, certain medications, and the intake of substances like caffeine, nicotine, or alcohol.

Country of origin

India

Manufacturer/Marketer address

16th Floor, Godrej BKC, Plot – C, “G” Block, Bandra-Kurla Complex, Bandra (East), Mumbai – 400 051, India
Other Info - ZOL0004

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Author Details

Veda MaddalaDoctor badge

Written By

Veda Maddala

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

May 20, 2025 | 6:21 PM IST

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Reference

  1. https://www.medicines.org.uk/emc/files/pil.8188.pdf
  2. https://www.accessdata.fda.gov/drugsatfda_docs/label/2008/019908s027lbl.pdf
  3. https://www.drugs.com/zolpidem.html
  4. https://www.nhs.uk/medicines/zolpidem/

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