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ZOLGASL CAPSULE belongs to a group of medicines called gastrointestinal agents used to treat gastro-oesophageal reflux disease (GERD). Gastroesophageal reflux disease occurs when stomach acid frequently flows back into the food pipe (oesophagus); this causes acidity, pain and heartburn. Symptoms include heartburn, sour or bitter taste in the mouth and difficulty swallowing.
ZOLGASL CAPSULE contains Esomeprazole and Levosulpiride. Esomeprazole works by blocking the action of an enzyme called gastric proton pump, which is responsible for the production of acid. Levosulpiride works by increasing the stomach and intestinal movement and pressure of the inferior oesophageal (food pipe) sphincter, thereby preventing the backflow of food and acid into the mouth. Together, ZOLGASL CAPSULE helps in preventing acid reflux, thereby providing relief from acidity and heartburn.
You are advised to take ZOLGASL CAPSULE for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side-effects such as headache, abdominal pain, constipation, diarrhoea, flatulence, nausea and vomiting. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.
Inform your doctor before taking ZOLGASL CAPSULE if you have a history of gastrointestinal bleeding or intestinal obstruction. On long-term treatment, ZOLGASL CAPSULE may increase the risk of bone fractures. Consult your doctor if you are pregnant or breastfeeding. ZOLGASL CAPSULE may cause drowsiness and dizziness, so drive only if you are alert. ZOLGASL CAPSULE should not be given to children as safety has not been established. Avoid consuming alcohol along with ZOLGASL CAPSULE as it could lead to increased drowsiness and can elevate the production of stomach acid.
ZOLGASL CAPSULE belongs to a group of medicines called gastrointestinal agents used to treat gastro-oesophageal reflux disease (GERD). ZOLGASL CAPSULE is a combination of two drugs, namely: Esomeprazole (proton pump inhibitor) and Levosulpiride (prokinetic agent). Esomeprazole works by blocking the action of an enzyme called gastric proton pump, which is responsible for the production of acid. Levosulpiride works by increasing the stomach and intestinal movement and pressure of the inferior oesophageal (food pipe) sphincter, thereby preventing the backflow of food and acid into the mouth. Together, ZOLGASL CAPSULE helps in preventing acid reflux, thereby providing relief from acidity and heartburn.
Do not take ZOLGASL CAPSULE if you are allergic to any of its contents, if you are taking nelfinavir (anti-HIV), if you have a gastrointestinal haemorrhage, mechanical obstruction or perforation, epilepsy, mania, porphyria, or cardiac impairment. Inform your doctor before taking ZOLGASL CAPSULE if you have severe liver or kidney problems; if you are due to have Chromogranin A test; if you experience unexplained weight loss, stomach pain, indigestion, vomit food or blood, or if you pass black stools. On long-term treatment, ZOLGASL CAPSULE may increase the risk of bone fractures. Do not take ZOLGASL CAPSULE if you are pregnant or breastfeeding. ZOLGASL CAPSULE may cause dizziness and drowsiness, so drive only if you are alert. ZOLGASL CAPSULE should not be given to children as safety has not been established. Avoid consuming alcohol along with ZOLGASL CAPSULE as it could lead to increased drowsiness and can elevate the production of stomach acid.
Drug-Drug Interactions: ZOLGASL CAPSULE may interact with painkillers (aspirin, naproxen), anti-HIV (atazanavir), blood thinner (clopidogrel, warfarin, cilostazol), anti-fungal (ketoconazole, itraconazole, voriconazole), anti-cancer (erlotinib, methotrexate), anti-depressant (citalopram, imipramine, clomipramine, duloxetine), anti-anxiety (diazepam), anti-convulsant (phenytoin), gastroprokinetic agent (cisapride), a drug used to treat heart problems (digoxin), immunosuppressant (tacrolimus), anti-tuberculosis (rifampicin).
Drug-Food Interactions: No interactions found/established.
Drug-Disease Interaction: Inform your doctor if you have epilepsy, mania, Clostridium difficile-associated diarrhoea (CDAD), liver disease, bone fractures, or hypomagnesemia (low levels of magnesium).
Gastroesophageal reflux disease (GERD): The stomach is usually protected from acid by a mucous layer. In some cases, due to excess acid production, the mucous layer gets eroded, which leads to complications like GERD, acidity, heartburn and peptic ulcers. Gastroesophageal reflux disease (GERD) occurs when stomach acid frequently flows back into the food pipe (oesophagus). This backflow (acid reflux) irritates the food pipe and causes heartburn and acidity. Symptoms include heartburn, sour or bitter taste in the mouth and difficulty swallowing.
Alcohol
Unsafe
Avoid consumption of alcohol while taking ZOLGASL CAPSULE. Alcohol intake leads to increased production of stomach acid, thereby increases acidity and heartburn.
Pregnancy
Unsafe
ZOLGASL CAPSULE should not be taken if you are pregnant. Consult your doctor before taking ZOLGASL CAPSULE if you are pregnant.
Breast Feeding
Unsafe
ZOLGASL CAPSULE may pass into breast milk. Consult your doctor before taking ZOLGASL CAPSULE if you are breastfeeding.
Driving
Caution
ZOLGASL CAPSULE may cause dizziness, drowsiness and blurred vision. Do not drive or operate machinery unless you are alert.
Liver
Unsafe
ZOLGASL CAPSULE should not be used in patients with hepatic impairment. Consult your doctor before taking ZOLGASL CAPSULE if you have a liver impairment or any concerns regarding this.
Kidney
Caution
Dose adjustment may be needed. Consult your doctor before taking ZOLGASL CAPSULE if you have kidney impairment or any concerns regarding this.
Children
Unsafe
ZOLGASL CAPSULE should not be given to children as the safety and effectiveness were not established.
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