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compositionComposition:MELATONIN-3MG+ZOLPIDEM-10MG
prescription
Prescription Medicine
info
Zolprate M-10 Tablet 10's

Zolprate M-10 Tablet 10's is used in the treatment of insomnia. It contains Zolpidem and Melatonin, which relaxes muscles, reduces anxiety, and helps to fall asleep. It may cause side effects such as nausea, headache, diarrhoea, drowsiness, and dizziness. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

MELATONIN-3MG+ZOLPIDEM-10MG

Manufacturer/Marketer :

Medtas Healthcare

Consume Type :

Oral

Expires on or after :

Jan-28

Return Policy :

Not Returnable

About Zolprate M-10 Tablet 10's

Zolprate M-10 Tablet 10's is prescribed for the short-term treatment of sleep disturbances, including difficulty falling asleep or staying asleep (insomnia). Its primary medical purpose is to restore a natural sleep cycle and help you achieve deep, restful sleep. It is typically used for individuals suffering from temporary insomnia or sleep cycle disruptions.

This medicine is generally taken once a day, immediately before you go to bed. It is important to use it consistently and exactly as directed by your doctor. For the best results, take this medicine on an empty stomach, and establish a relaxing bedtime routine to help your body prepare for rest.

Some people may experience mild side effects, such as daytime drowsiness or dry mouth. However, if you experience serious side effects, such as confusion, severe dizziness, or performing activities while asleep (like sleepwalking), you must contact your doctor immediately.

Talk to your doctor or pharmacist before starting this medicine if you have a history of liver problems, depression, mental health conditions, or chronic breathing difficulties. Do not take this medicine if you have severe liver damage or severe breathing disorders. If you have previously experienced sleepwalking or other complex sleep behaviours, tell your doctor before starting treatment, as your doctor will carefully assess whether this medicine is appropriate for you.

Taking this medicine with alcohol can cause extreme drowsiness and dangerous breathing difficulties. Always tell your doctor about other medications you are taking, and consult your doctor or pharmacist if you are pregnant, breastfeeding, or an older adult, as safety precautions may vary. This medicine is generally intended for short-term use, usually for no longer than 2 to 4 weeks, unless your doctor advises otherwise. If your sleep problems continue, worsen, or return after treatment, do not increase your dose on your own.

Uses of Zolprate M-10 Tablet 10's

Zolprate M-10 Tablet 10's is used in the treatment of Insomnia (sleeplessness). The detailed use of Zolprate M-10 Tablet 10's is as follows:

  • Insomnia: Helps reduce the time it takes to fall asleep and decreases nightly awakenings.
  • Sleep-wake cycle disruptions: Relieves sleep problems caused by jet lag or irregular sleep schedules, helping reset your internal biological clock.

Key Benefits

Zolprate M-10 Tablet 10's helps improve sleep by making it easier to fall asleep and stay asleep through the night. A better night's rest can leave you feeling more refreshed, alert, and ready for your daily activities.

Benefits may include:

  • Helps you fall asleep more quickly.
  • Reduces frequent waking during the night.
  • Improves overall sleep quality and duration.
  • Supports a more regular and restful sleep pattern.
  • Promotes better daytime alertness, focus, and energy.
  • Provides relief from symptoms of short-term insomnia.

Directions for Use

  • Take this medicine by mouth immediately before bedtime.
  • Swallow the tablet whole with a full glass of water.
  • Do not crush, chew, or break the tablet, as this can affect how the medicine is released into your body.
  • Ensure you have a full 7 to 8 hours to dedicate to sleep after taking this medicine.

How Zolprate M-10 Tablet 10's Works

Zolprate M-10 Tablet 10's contains two active components that target sleep through different pathways in the body. • Zolpidem: It belongs to a group of medicines called non-benzodiazepine hypnotics. It enhances the effect of a natural calming chemical in the brain called GABA, helping slow brain activity so you can relax, fall asleep more quickly, and stay asleep. • Melatonin: It is a hormone naturally produced by your body that helps regulate your sleep-wake cycle. This medicine supplies an additional dose of melatonin to reinforce your body's natural sleep signal, helping you recognise that it is time to sleep and supporting a more regular sleep pattern.
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Alcohol

Unsafe

Avoid consumption of alcohol with Zolprate M-10 Tablet 10's as it may increase the risk of dependence, psychomotor impairment (slowdown of thought process, and reduced physical movements), sleepwalking, or sleep-driving.

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Pregnancy

Unsafe

Zolprate M-10 Tablet 10's contains Zolpidem, a Category C pregnancy drug, and is not recommended for use during pregnancy as it may cause adverse effects in the baby after birth.

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Breast Feeding

Unsafe

Avoid breastfeeding while taking Zolprate M-10 Tablet 10's as it may be excreted in breast milk.

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Driving

Unsafe

You may experience dizziness, drowsiness, confusion, decreased alertness, blurred, or double vision, especially the day after taking Zolprate M-10 Tablet 10's. Therefore, avoid driving if you feel drowsy or dizzy after taking Zolprate M-10 Tablet 10's.

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Liver

Caution

Take Zolprate M-10 Tablet 10's with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Zolprate M-10 Tablet 10's with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Caution

Zolprate M-10 Tablet 10's is not recommended for children below 18 years of age.

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Heart

Caution

Zolprate M-10 Tablet 10's should be taken with extreme caution in patients with heart disease. Please consult your physician.

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Geriatrics

Unsafe

Zolprate M-10 Tablet 10's is not safe for use in elderly patients due to its serious side effects.

What if I have taken an overdose of Zolprate M-10 Tablet 10's

If you suspect an overdose, seek immediate medical attention or call emergency services. Symptoms of an overdose may include extreme sleepiness, confusion, severe dizziness, or slowed breathing.

Diet & Lifestyle Advise

  • Create a restful bedroom: Keep your bedroom dark, quiet, and comfortably cool to create an environment that supports better sleep.
  • Limit bedtime triggers: Avoid heavy meals, caffeine, and drinking large amounts of fluids close to bedtime to reduce the chance of waking up during the night.
  • Reduce screen time: Switch off phones, televisions, and other electronic devices at least one hour before bed to help your body prepare for sleep.
  • Follow a regular schedule: Go to bed and wake up at the same time every day, including weekends, to help maintain a healthy sleep routine.

Have a query?

How Soon It Starts Working

  • The time required for Zolprate M-10 Tablet 10's to start to work: The time required for Zolprate M-10 Tablet 10's to show its action is unknown.
  • The time for which the effects of Zolprate M-10 Tablet 10's last: The duration of action for Zolprate M-10 Tablet 10's is clinically unknown.

What if you forget to take Zolprate M-10 Tablet 10's

If you forget to take your medicine at bedtime, only take it if you can immediately go to sleep and have a full 7 to 8 hours to remain asleep. If you do not have 7 to 8 hours of sleep time left before you must be active, skip the missed dose entirely and resume your normal schedule the next night. Never take a double dose to make up for a missed one.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

  • Take only at bedtime: Take this medicine only when you are ready to go to bed and can sleep for a full night. This helps reduce the risk of feeling sleepy or less alert the next day.
  • Avoid driving or hazardous activities: Do not drive, operate machinery, or do anything that requires full alertness the next morning until you know how this medicine affects you.
  • Watch for unusual sleep behaviours: Stop taking this medicine and contact your doctor immediately if you or your family notice activities such as sleepwalking, eating, driving, or making phone calls while you are asleep.
  • Avoid alcohol completely: Do not drink alcohol while taking this medicine. Alcohol can greatly increase drowsiness and raise the risk of serious side effects.
  • Use only as prescribed: Take this medicine only if it has been prescribed for you. Do not share it with others, as improper use can lead to dependence, misuse, or serious side effects.
  • Not for children: This medicine is generally not recommended for children and adolescents under 18 years of age. Its safety and effectiveness have not been established in this age group.

verifiedApollotooltip
  • Sleep Aids or Sedatives (e.g., eszopiclone, zaleplon): Taking these medicines alongside Zolprate M-10 Tablet 10's may increase the risk of severe drowsiness, confusion, and breathing problems.
  • Opioid Pain Relievers (e.g., tramadol, morphine): Taking these medicines alongside Zolprate M-10 Tablet 10's may increase the risk of extreme drowsiness, slowed breathing, coma, or death.
  • Antidepressants or Psychiatric Medicines (e.g., fluoxetine, amitriptyline): Taking these medicines alongside Zolprate M-10 Tablet 10's may increase the risk of excessive drowsiness and other side effects.

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verifiedApollotooltip
  • High-Fat Meals: Consuming fried foods, pizza, burgers, or creamy meals while taking Zolprate M-10 Tablet 10's may delay how quickly the medicine starts working.
  • Alcohol: Consuming alcohol while taking Zolprate M-10 Tablet 10's may increase the risk of extreme drowsiness, confusion, slowed breathing, or impaired alertness.

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All Substitutes & Brand Comparisons

Habit Forming

Yes

Therapeutic Class

[SEDATIVE-HYPNOTIC DRUGS]

FAQs

Zolprate M-10 Tablet 10's is used in the treatment of insomnia.
Zolprate M-10 Tablet 10's is a sleeping pill used to treat insomnia (difficulty in falling or staying asleep). Zolpidem increases the activity of GABA (a chemical messenger in the brain that acts as a natural nerve-calming agent) involved in inducing sleep. Melatonin is a natural hormone that helps to maintain the normal sleep cycle (waking up and falling asleep)
No, Zolprate M-10 Tablet 10's is not recommended for depression patients as it may worsen the condition and increase self-harming or suicidal thoughts. Therefore, if you are suffering from depression or have a history of depression, please inform your doctor before taking Zolprate M-10 Tablet 10's.
You are recommended to take Zolprate M-10 Tablet 10's just before bedtime as it helps to sleep quickly and improves sleep quality. If you forget to take Zolprate M-10 Tablet 10's at night, do not take it in the day time as it may cause drowsiness, confusion and dizziness.
No, you are not recommended to take Zolprate M-10 Tablet 10's with hydrocodone or other opioid pain killers such as oxycodone, naloxone, and tramadol as co-administration of these medicines with Zolprate M-10 Tablet 10's may increase the risk of difficulty in breathing, drowsiness, coma, and even death. However, before using Zolprate M-10 Tablet 10's with any other medicines, you are advised to contact your doctor so that the dose may be adjusted to use safely.
Yes, Zolprate M-10 Tablet 10's may cause dependence (mental and physical effects caused due to compulsion of taking Zolprate M-10 Tablet 10's) if used in high doses and for a prolonged time. This risk of dependency on Zolprate M-10 Tablet 10's increases in patients who have a history of drug or alcohol abuse.
No, you should only take this medicine if you have a full 7 to 8 hours to sleep. Taking it with less sleep time can cause severe morning drowsiness and make activities like driving dangerous. Talk to your doctor if your schedule does not allow a full night's sleep.
No. This medicine is intended for short-term use, usually no longer than 2 to 4 weeks, unless your doctor advises otherwise. Using it every night for longer periods may increase the risk of tolerance, dependence, and withdrawal symptoms if it is stopped suddenly. Your doctor will review your condition if longer treatment is needed.
If you experience sleepwalking or any other sleep behaviours, stop taking the medicine immediately and call your doctor. These side effects can be dangerous and require alternative medical advice.
No, you must completely avoid alcohol while taking this medicine. Combining them can cause severe drowsiness, confusion, and dangerously slow breathing.
Using this medicine during pregnancy is generally not recommended unless deemed necessary by your healthcare provider. Talk to your doctor to weigh the risks and benefits.
Some people may experience morning drowsiness, especially if they do not get a full 7 to 8 hours of sleep. If you feel groggy, avoid driving or operating machinery and talk to your doctor.
It is best to take this medicine on an empty stomach right before bed. Taking it with a heavy meal can delay its effects, meaning it will take longer for you to fall asleep.
If you wake up during the night and forgot your dose, only take it if you still have 7 to 8 hours of uninterrupted sleep time remaining. Otherwise, skip the dose and resume your regular schedule the next night. Talk to your doctor if you have further concerns.
If your sleep does not improve within 7 to 10 days, worsens, or returns after treatment, schedule a follow-up with your doctor. Persistent insomnia may be caused by another medical or mental health condition that requires further evaluation. Do not increase your dose or continue taking the medicine longer than prescribed without medical advice.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. U.S. Food and Drug Administration (FDA). 019908S027Lbl [FDA Prescribing Information]. Silver Spring, MD: FDA; 2024. [Accessed on 02 Jun. 2026] Check here
  2. Drugs.com Clinical Review Team. Zolpidem Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026] Check here
  3. National Health Service (NHS). Zolpidem - NHS Medicines Reference Guide. London, UK: NHS; 2025. [Accessed on 02 Jun. 2026] Check here
  4. Electronic Medicines Compendium (EMC). Pil.10405 Patient Information Leaflet (PIL). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026] Check here
  5. Drugs H. Zolpidem: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2022 [Accessed on 24 Nov 2025] Check here
  6. CDSCO [Internet]. Cdscoonline.gov.in. 2022 [Accessed on 24 Nov 2025] Check here
  7. [Internet]. Rxlist.com. 2022 [Accessed on 24 Nov 2025]Check here

Country of origin

India

Manufacturer/Marketer address

Medtas Healthcare
Other Info - ZOL0379

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