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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Manufacturer/Marketer :

Eris Life Sciences Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Zomelis Met 50 mg/1000 mg Tablet

Zomelis Met 50 mg/1000 mg Tablet is an oral prescription medication used to treat type 2 diabetes mellitus in adults. Its primary medical purpose is to help control high blood sugar levels when diet, exercise, and other single-ingredient medicines are not sufficient. By keeping blood sugar within a target range, it helps prevent long-term health complications associated with diabetes.

For this medicine to work effectively, you must take it consistently every day at the same times as directed by your doctor. It is usually taken once or twice a day, and it is best taken with or immediately after a meal to reduce the chance of an upset stomach. Combining this medication with healthy dietary habits and regular physical activity is essential to achieve the best possible blood sugar control.

While taking Zomelis Met 50 mg/1000 mg Tablet , you may experience some mild, temporary side effects, such as nausea, a mild headache, or a metallic taste in your mouth. However, you must contact your doctor immediately if you experience serious symptoms like severe, persistent stomach pain, dark urine, or yellowing of your skin or eyes.

Before starting Zomelis Met 50 mg/1000 mg Tablet , tell your doctor if you have a history of kidney disease, liver damage, congestive heart failure, or severe infections. Do not take this if you have severe kidney failure or diabetic ketoacidosis or if you are allergic to any of its active ingredients.

This medicine can interact with alcohol, which can increase the risk of a rare but serious metabolic complication called lactic acidosis. While the combination itself generally has a low risk of causing low blood sugar (hypoglycaemia), the risk becomes higher when it is used together with insulin or sulfonylurea medicines. It can also interact with water pills or steroids, altering its effectiveness. If you are pregnant, planning to become pregnant, breastfeeding, or an elderly patient, consult your healthcare provider to discuss whether this treatment is safe for you.

Uses of Zomelis Met 50 mg/1000 mg Tablet

Before understanding its specific medical use, it is important to know how this medicine supports blood sugar management in people with diabetes:

  • Type 2 Diabetes Mellitus: Zomelis Met 50 mg/1000 mg Tablet is prescribed to improve blood sugar control in adults whose high blood sugar cannot be managed by diet, exercise, or other single oral diabetes medications alone.

Key Benefits

This medicine provides several important benefits that help improve both daily diabetes management and long-term health outcomes:

  • Zomelis Met 50 mg/1000 mg Tablet offers real-world relief by helping you manage your daily blood sugar levels more predictably. When your blood sugar is stable, you are less likely to experience the sudden fatigue, extreme thirst, and frequent urination associated with high blood sugar spikes.
  • In the long term, keeping your blood sugar in check with this medicine helps protect your vital organs. It significantly reduces the risk of serious diabetes complications, including kidney damage, nerve pain, vision loss, and cardiovascular problems like heart attacks or strokes.
Side effects of Zomelis Met 50 mg/1000 mg Tablet
  • Drink warm fluids such as warm water with honey, broth, soup or herbal tea to soothe sore throat.
  • Gargle with warm salt water.
  • Suck on lozenges to increase the production of saliva and soothe your throat.
  • Use a humidifier to soothe sore throat as it adds moisture to the air and makes breathing easier.
  • To help reduce symptoms, eat foods high in vitamin C, such as oranges, bell peppers and strawberries.
  • Lightly blow your nose to remove mucus; steer clear of blowing hard.
  • Infections can be prevented from spreading by washing hands frequently and staying away from other people.
  • If you have allergies, do your best to avoid triggering allergens that could contribute to a runny nose.
  • Don't smoke, as irritating the nasal passages can make a runny nose worse.
Here's a comprehensive approach to managing medication-triggered fever:
  • Inform your doctor immediately if you experience a fever after starting a new medication.
  • Your doctor may adjust your medication regimen or dosage as needed to minimize fever symptoms.
  • Monitor your body temperature to monitor fever progression.
  • Drink plenty of fluids, such as water or electrolyte-rich beverages, to help your body regulate temperature.
  • Get plenty of rest and engage in relaxation techniques, such as deep breathing or meditation, to help manage fever symptoms.
  • Under the guidance of your doctor, consider taking medication, such as acetaminophen or ibuprofen, to help reduce fever.
  • If your fever is extremely high (over 103°F), or if you experience severe symptoms such as confusion, seizures, or difficulty breathing, seek immediate medical attention.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.

Directions for Use

To get the maximum benefit from your medication, follow these simple steps:

  • Swallow the tablet whole with a full glass of water.
  • Do not crush, chew, or break the tablet, as this can alter how the medicine is absorbed in your body.
  • Take the medicine with or immediately after a meal to minimise stomach discomfort.
  • Always follow your doctor's exact instructions regarding how often and when to take your medicine.

How Zomelis Met 50 mg/1000 mg Tablet Works

Zomelis Met 50 mg/1000 mg Tablet contains two active medicines that work together in different ways to control blood sugar. The first active ingredient, metformin, works primarily by reducing the amount of sugar your liver releases into your bloodstream. It also makes your body's cells more sensitive to insulin, allowing them to absorb and use sugar from your blood more effectively. The second active ingredient, vildagliptin, belongs to a group of medicines called DPP-4 (dipeptidyl peptidase-4) inhibitors. It works by helping your pancreas produce more insulin after you eat, which helps clear sugar from your blood. At the same time, it reduces the release of a hormone that tells your liver to produce more sugar. Together, these actions help provide more balanced and steady control of blood glucose throughout the day.
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Alcohol

Unsafe

It is best to avoid alcohol while taking medication.

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Pregnancy

Consult your doctor

Please consult your doctor for advice before using Zomelis Met 50 mg/1000 mg Tablet .

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Breast Feeding

Consult your doctor

Please consult your doctor for advice before using Zomelis Met 50 mg/1000 mg Tablet .

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Driving

Unsafe

Drive only if you are physically stable and mentally focussed, If you experience drowsiness after taking these medications you should not drive or operate any machinery or vehicles.

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Liver

Consult your doctor

If u have or had history or evidence of any liver-related diseases, please consult the doctor before taking the medicine.

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Kidney

Consult your doctor

If u have or had history or evidence of any kidney-related diseases, please consult the doctor before taking the medicine.

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Children

Consult your doctor

It is advisable to consult a doctor before using it.

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Heart

Consult your doctor

Zomelis Met 50 mg/1000 mg Tablet should be used with caution if you have any cardiac problems. This medicine is contraindicated in patients with severe heart failure.

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Geriatrics

Caution

Caution should be exercised in geriatric patients while taking Zomelis Met 50 mg/1000 mg Tablet .

What if I have taken an overdose of Zomelis Met 50 mg/1000 mg Tablet

Do not take more than the prescribed dose of Zomelis Met 50 mg/1000 mg Tablet as it may cause overdose symptoms like extreme tiredness, weakness, discomfort, vomiting, nausea, stomach pain, decreased appetite, deep, rapid breathing, liver disease, and rhabdomyolysis with DKA. If you suspect you have taken an overdose, please consult a doctor immediately.

Diet & Lifestyle Advise

  • Choose complex carbohydrates: Focus on high-fiber foods such as whole grains, vegetables, and legumes, which release sugar slowly into your bloodstream and prevent sudden spikes.
  • Maintain regular physical activity: Engage in at least 30 minutes of moderate exercise, like brisk walking, most days of the week to help your body use insulin more efficiently.
  • Monitor your blood sugar: Check your blood glucose levels regularly as recommended by your doctor to track your progress and detect any unusual patterns.
  • Stay hydrated: Drink plenty of water throughout the day to support kidney function and help your body process the medication safely.
  • Limit alcohol intake: Avoid heavy drinking, as alcohol can interfere with your blood sugar levels and increase the risk of severe side effects.

Have a query?

How Soon It Starts Working

The time required for Zomelis Met 50 mg/1000 mg Tablet to start to work: The time required for Zomelis Met 50 mg/1000 mg Tablet to show its action is unknown. The time for which the effects of Zomelis Met 50 mg/1000 mg Tablet last: The duration of action for Zomelis Met 50 mg/1000 mg Tablet is unknown.

What if you forget to take Zomelis Met 50 mg/1000 mg Tablet

If you miss a dose of Zomelis Met 50 mg/1000 mg Tablet , take it as soon as you remember. However, if it is almost time for the next dose, skip the missed one and continue with your regular schedule. Do not take a double dose to make up for the missed one.

Storage

• Store Zomelis Met 50 mg/1000 mg Tablet tablets at room temperature, ideally below 30°C (86°F). • Keep the tablets in their original blister packaging to protect them from moisture and direct light.

Drug Warnings

  • Get regular kidney and liver tests: Your doctor will perform routine blood tests to check your kidney and liver function while you are taking this medicine.
  • Know the signs of low blood sugar: Learn to recognise symptoms like sweating, shakiness, dizziness, and fast heartbeat. Always carry a fast-acting sugar source, such as fruit juice, glucose tablets, or hard candy, to treat low blood sugar quickly.
  • Inform your surgical team: If you need surgery or any medical imaging procedure that uses contrast dyes, tell your doctor. You may need to stop taking this medicine temporarily.
  • Inspect your tablets: Always check your medicine packaging before use. Do not take the tablets if the blister foil is torn, damaged, or shows signs of tampering.
  • Avoid dehydration: If you experience severe vomiting, diarrhoea, or high fever, contact your doctor, as severe dehydration can increase the risk of serious side effects.

Drug-Drug Interactions

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Drug-Drug Interactions

These medicines or combinations can significantly affect how Zomelis Met 50 mg/1000 mg Tablet works in your body, either increasing side effects or reducing its blood sugar control:

  • Water pills (diuretics) and steroids: May raise your blood sugar levels, reducing the effectiveness of Zomelis Met 50 mg/1000 mg Tablet .
  • Other blood sugar-lowering medicines (especially insulin or sulfonylureas): The risk of low blood sugar (hypoglycaemia) is mainly increased when Zomelis Met 50 mg/1000 mg Tablet is combined with insulin or sulfonylureas, as the combination can lead to excessive glucose lowering.
  • Blood pressure medications (including ACE inhibitors): Some studies suggest a possible increased sensitivity to blood sugar-lowering effects, which may slightly raise the risk of hypoglycaemia in certain patients. Close monitoring may be required, especially when starting or adjusting doses.


Drug-Food Interactions

Some foods and drinks can interfere with how safely this medicine works in your body:

  • Alcohol: Avoid or strictly limit alcohol while taking this medicine. Alcohol significantly increases the risk of a rare but serious condition called lactic acidosis (acid buildup in the blood). It may also contribute to low blood sugar, particularly if you are taking insulin or sulfonylureas alongside this medicine.


Drug-Disease Interactions

Certain existing health conditions can increase the risk of serious side effects or reduce the safety of this medicine:

  • Severe kidney disease: If your kidneys are not working properly, this medicine can build up in your body, increasing the risk of serious side effects.
  • Liver damage: People with significant liver disease should use this medicine only under close medical supervision. Impaired liver function can reduce the body's ability to clear lactate, increasing the risk of lactic acidosis associated with metformin. In addition, vildagliptin has been associated with liver enzyme abnormalities, so regular liver function monitoring may be required during treatment.
  • Heart failure: If you have unstable or severe heart failure, your risk of reduced oxygen supply to tissues and subsequent acid buildup is increased.

Drug-Drug Interactions

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How does the drug interact with Zomelis Met 50 mg/1000 mg Tablet:
The combined use of Zomelis Met 50 mg/1000 mg Tablet and Zonisamide may increase the risk of side effects.

How to manage the interaction:
Coadministration of Zomelis Met 50 mg/1000 mg Tablet and Zonisamide can lead to an interaction, it can be taken if prescribed by your doctor. However, if you experience any unusual symptoms, consult a doctor immediately. Do not stop using any medication without a doctor's advice.
How does the drug interact with Zomelis Met 50 mg/1000 mg Tablet:
The combined use of Zomelis Met 50 mg/1000 mg Tablet and Topiramate may increase the risk of side effects.

How to manage the interaction:
Coadministration Zomelis Met 50 mg/1000 mg Tablet and Topiramate can lead to an interaction, it can be taken if prescribed by your doctor. However, if you experience any unusual symptoms, consult the doctor immediately. Do not stop using any medication without a doctor's advice.
Severe
How does the drug interact with Zomelis Met 50 mg/1000 mg Tablet:
Co-administration of Zomelis Met 50 mg/1000 mg Tablet with Methazolamide may increase the risk of side effects.

How to manage the interaction:
Although there is a possible interaction between Zomelis Met 50 mg/1000 mg Tablet and Methazolamide, you can take these medicines together if prescribed by your doctor. However, if you have any unusual symptoms, contact a doctor immediately. Do not stop using any medications without a doctor’s advice.
How does the drug interact with Zomelis Met 50 mg/1000 mg Tablet:
Co-administration of Zomelis Met 50 mg/1000 mg Tablet with Ethanol may increase the risk of side effects including Lactic acidosis (excessive lactic acid production in blood).

How to manage the interaction:
Although there is a possible interaction between Zomelis Met 50 mg/1000 mg Tablet and Ethanol, you can take these medicines together if prescribed by your doctor. However, if you have ay unusual symptoms, contact a doctor immediately. Do not stop using any medications without a doctor’s advice.
How does the drug interact with Zomelis Met 50 mg/1000 mg Tablet:
Co-administration of Zomelis Met 50 mg/1000 mg Tablet with Acetazolamide may increase the risk of side effects including Lactic acidosis (excessive lactic acid production in the blood).

How to manage the interaction:
Although there is a possible interaction between Zomelis Met 50 mg/1000 mg Tablet and Acetazolamide, you can take these medicines together if prescribed by your doctor. However, if you have any unusual symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[ANTIDIABETICS]

FAQs

Zomelis Met 50 mg/1000 mg Tablet is an antidiabetic medicine used in addition to diet and exercise to improve control of blood glucose (sugar) levels in adults with type 2 diabetes.

Zomelis Met 50 mg/1000 mg Tablet help to control the level of sugar in the blood. The substance vildagliptin works by making the pancreas produce more insulin and less glucagon. The substance metformin works by helping the body to make better use of insulin. This medicine has been shown to reduce blood sugar, which may help to prevent complications from your diabetes.

If you have symptoms like increased hunger, increased thirst, frequent urination (usually at night), unexplained weight loss, fatigue, blurred vision, slow wound/sores healing, and frequent infections, contact doctor as it can be a condition of type 2 diabetes.

No. Zomelis Met 50 mg/1000 mg Tablet is only prescribed for the treatment of type 2 diabetes also called as 'non-insulin-dependent diabetes'.

Type 2 diabetes is a common form of diabetes in which the blood sugar-lowering hormone called insulin produced by the body does not function properly. Due to this, the blood glucose level increases, and symptoms such as frequent urination, increased thirst, and increased hunger start. Diabetes, if left untreated or not treated properly, can cause long-term complications such as nerve damage, kidney damage, eye damage, foot problems, and also poses a high risk of developing heart diseases.

The medicine should be swallowed as a whole with water. Do not crush, break or chew it.

Include a diet rich in fruits, vegetables and whole grains like brown rice, whole wheat, oats, barley, and quinoa. Non-fat or low-fat dairy and proteins like chicken, lean meats, nuts, beans, tofu, lentils, eggs, fish, and turkey can also be included.

Zomelis Met 50 mg/1000 mg Tablet contains two anti-diabetic medicines, Vildagliptin (DPP-4 inhibitor) and Metformin (biguanides) which help manage blood glucose levels.

Zomelis Met 50 mg/1000 mg Tablet may cause side effects such as nausea, headache, shaking or quivering, vomiting, diarrhoea, abdominal pain, loss of appetite, joint pain, tiredness, constipation, and oedema.

Zomelis Met 50 mg/1000 mg Tablet may cause hypoglycaemia (low blood glucose levels), which is characterised by dizziness, sweating, palpitations, hunger pangs, dry mouth and skin. Regularly monitor blood glucose levels and consume glucose tablets, juice or candy if you experience these symptoms.

Zomelis Met 50 mg/1000 mg Tablet may cause side effects such as nausea and vomiting. If you experience these symptoms eat smaller meals more often and avoid hard-to-digest food. Take small, frequent sips of water or any other fluids. Consult the doctor if the condition persists or worsens.

Zomelis Met 50 mg/1000 mg Tablet is contraindicated in people who are allergic to any of its components. It is not recommended for people with uncontrolled diabetes, ketoacidosis, severely reduced kidney function, severe infection, heart failure, or serious blood circulation problems.

Zomelis Met 50 mg/1000 mg Tablet should be stored at room temperature (below 30°C). Keep it away from the reach and sight of children.

Zomelis Met 50 mg/1000 mg Tablet may cause lactic acidosis (a very rare, but very serious side effect in which lactic acid builds up in the blood), particularly if your kidneys are not working properly. The risk of developing lactic acidosis is also increased with uncontrolled diabetes, prolonged fasting or alcohol intake, serious infections, dehydration, liver problems and any medical conditions in which a part of the body has a reduced supply of oxygen (such as acute severe heart disease). Consult the doctor if you notice symptoms of lactic acidosis like abdominal pain, vomiting, muscle cramps, difficulty breathing, reduced body temperature and heartbeat, and a general feeling of not being well with severe tiredness.

Zomelis Met 50 mg/1000 mg Tablet may interfere with the absorption of vitamin B12 leading to its deficiency on long-term use. Consult the doctor if you notice signs of vitamin B12 deficiency like pale/yellow skin, headache, fatigue, anaemia, and depression.

Yes, it is safe to use Zomelis Met 50 mg/1000 mg Tablet if prescribed by the doctor. Zomelis Met 50 mg/1000 mg Tablet has a good safety profile with robust glucose-lowering efficacy.

If you experience symptoms of low blood sugar (such as shaking, sweating, or dizziness), consume a fast-acting sugar source immediately, like half a cup of fruit juice, soda, or a few hard candies. If symptoms persist, contact your doctor or seek medical help.

No, Zomelis Met 50 mg/1000 mg Tablet is generally weight-neutral. The active medicines in this combination do not typically cause weight gain, and some patients may even experience modest weight loss when combined with a proper diet and exercise plan. Talk to your doctor for personalised advice.

It is best to avoid alcohol while taking this medicine. Alcohol significantly increases the risk of severe low blood sugar and a rare but dangerous condition called lactic acidosis. Talk to your doctor or pharmacist if you have concerns.

The medicine begins lowering blood glucose within hours to days of starting treatment due to its direct pharmacological action. However, noticeable and meaningful improvements in long-term blood sugar control (HbA1c levels) typically take about 8-12 weeks, or approximately 3 months, of consistent use along with diet and lifestyle changes.

This medicine is generally not recommended during pregnancy or breastfeeding. Managing diabetes during pregnancy usually requires insulin therapy under close medical supervision. Talk to your doctor for safe alternatives.

You should take Zomelis Met 50 mg/1000 mg Tablet at the exact times prescribed by your doctor. It is usually taken once in the morning or twice daily (morning and evening) with your meals to maintain consistent medicine levels in your body.

The medicine itself does not typically cause kidney damage, but it is cleared from your body through your kidneys. If your kidneys are not functioning well, the medicine can build up and cause serious side effects. Your doctor will test your kidney function regularly.

Continue taking Zomelis Met 50 mg/1000 mg Tablet for as long as your doctor recommends. Do not stop taking it without medical advice, even if your blood sugar improves, as stopping treatment may cause your blood sugar levels to rise again. Consult your doctor if you have concerns about continuing the medicine.

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Country of origin

India

Manufacturer/Marketer address

401, LSC, C-Block, Mohan Place Saraswati Vihar Delhi DL 110034 In
Other Info - ZOM0033
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