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  1. Home
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  3. Zonalta 8 mg Tablet 10's

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Zonalta 8 mg Tablet 10's, Pack of 10 TabletS
Zonalta 8 mg Tablet 10's, Pack of 10 TabletS
Zonalta 8 mg Tablet 10's, Pack of 10 TabletS
Zonalta 8 mg Tablet 10's, Pack of 10 TabletS
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Composition :

ENDOXIFEN-8MG

Manufacturer/Marketer :

Intas Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Zonalta 8 mg Tablet 10's

Zonalta 8 mg Tablet 10's is used to treat or reduce the symptoms of manic episodes in bipolar I illness, with or without mixed characteristics (both highs and lows at the same time).

Zonalta 8 mg Tablet 10's contains 'Endoxifen,' which works by managing certain chemicals in the brain that control your moods, such as serotonin, norepinephrine, and dopamine.

Zonalta 8 mg Tablet 10's may cause side effects such as headache, vomiting, abdominal discomfort, and diarrhoea. Most of these side effects do not require medical attention and will resolve gradually over time. However, consult your doctor if the side effects persist or worsen.

Do not stop taking Zonalta 8 mg Tablet 10's without consulting your doctor to avoid worsening your condition. Keep your healthcare professional informed about your medical condition and your medications to rule out any potential negative effects and interactions.

Uses of Zonalta 8 mg Tablet 10's

Zonalta 8 mg Tablet 10's is used in the treatment of Acute manic episodes in adults associated with bipolar disorder. The detailed uses of Zonalta 8 mg Tablet 10's are as follows:

  • Treat manic and mixed episodes in bipolar I disorder: Zonalta 8 mg Tablet 10's is primarily used to manage acute mania and mixed mood states in patients with bipolar I disorder. It helps stabilise mood and reduce symptoms such as elevated energy, impulsivity, and irritability.
  • Modulate brain signalling and neurotransmitter balance: Zonalta 8 mg Tablet 10's works by directly inhibiting protein kinase C (PKC), a key enzyme involved in overactive neuronal signalling. This action helps regulate neurotransmitters like dopamine, serotonin, and norepinephrine that influence mood and behaviour.

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Directions for Use

  • Zonalta 8 mg Tablet 10's can be taken with or without food, as food intake does not significantly influence its effectiveness.
  • Adhere to your doctor's guidance regarding the dosage and timing of this medication for optimal effectiveness.
  • Swallow Zonalta 8 mg Tablet 10's as a whole with a glass of water.
  • Do not crush, chew, or break it.

Medicinal Benefits

  • Zonalta 8 mg Tablet 10's helps in the management of bipolar disorder, particularly during the manic phase.
  • It inhibits protein kinase C activity, which is elevated in mania, thereby restoring balance in brain activity.
  • It regulates important brain chemicals such as serotonin, norepinephrine, and dopamine to stabilise mood.
  • Zonalta 8 mg Tablet 10's reduces manic symptoms, including irritability, hyperactivity, and elevated mood.
  • It is effective in controlling mixed episodes (both highs and lows occurring simultaneously).
  • Zonalta 8 mg Tablet 10's improves the overall severity of illness, enhancing the quality of life in patients with bipolar disorder.

How Zonalta 8 mg Tablet 10's Works

Zonalta 8 mg Tablet 10's contains 'Endoxifen,' which works in the nervous system by inhibiting protein kinase C activity (which is elevated in patients with bipolar I illness during their manic phase) and thus helps to manage certain chemicals in the brain that control your moods, such as serotonin, norepinephrine, and dopamine.

Storage

• Store in a cool and dry place away from sunlight.• Keep Zonalta 8 mg Tablet 10's out of the sight and reach of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Zonalta 8 mg Tablet
Here are the 7 step-by-step strategies to manage the side effect of "inability to sleep" caused by medication usage:
  • Prepare for a restful night's sleep: Develop a calming pre-sleep routine, like reading or meditation, to help your body relax and prepare for sleep.
  • Create a sleep-conducive Environment: Make bedroom a sleep haven by ensuring it is quiet, dark and calm.
  • Follow a Sleep Schedule: Go to bed and get up at the same time every day to help regulate your body's internal clock and increase sleep quality.
  • Try relaxing techniques like deep breathing, mindfulness meditation and any others.
  • Limit stimulating activities before bedtime: Avoid stimulating activities before bedtime to improve sleep quality.
  • Monitor Progress: Keep track of your sleep patterns to identify areas for improvement.
  • Consult a doctor if needed: If these steps don't improve your sleep, consult a doctor for further guidance and therapy.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
Here are the step-by-step strategies to manage the side effects of "indigestion" caused by medication usage:
  • Take medications with food (if recommended): It can help prevent stomach distress and indigestion.
  • Eat smaller, more frequent meals: Divide daily food intake into smaller, more frequent meals to ease digestion.
  • Avoid trigger foods: Identify and avoid foods that trigger indigestion, such as spicy, fatty, or acidic foods.
  • Stay upright after eating: Sit or stand upright for at least 1-2 hours after eating to prevent stomach acid from flowing into the oesophagus.
  • Avoid carbonated drinks: Avoid drinking carbonated beverages, such as soda or beer, which can worsen indigestion.
  • Manage stress: To alleviate indigestion, engage in stress-reducing activities like deep breathing exercises or meditation.
  • Consult a doctor if needed: If indigestion worsens or persists, consult a healthcare professional to adjust the medication regimen or explore alternative treatments.
  • Prefer liquid food like juices and soups when you are not likely to eat.
  • Avoid spicy, fatty and fried foods as they cause stomach upset.
  • Eat small and frequent meals, avoiding large meals at a time.
  • Add healthy foods in your diet like fruits and vegetables.
  • Take starchy food like cereals, bread and potatoes etc.

What if I have taken an overdose of Zonalta 8 mg Tablet 10's

An overdose of Zonalta 8 mg Tablet 10's may cause unpleasant side effects. If you suspect you have taken an overdose, please consult a doctor immediately.

Drug Warnings

  • Avoid taking Zonalta 8 mg Tablet 10's if you are allergic to any of its components.
  • Do not stop taking Zonalta 8 mg Tablet 10's without consulting your doctor to avoid worsening your condition.
  • To treat your condition effectually, continue taking Zonalta 8 mg Tablet 10's for as long as your doctor has suggested, even if you feel better.
  • Do not take Zonalta 8 mg Tablet 10's if you are pregnant or breastfeeding.
  • It is recommended to use effective contraceptive methods while using Zonalta 8 mg Tablet 10's.
  • Zonalta 8 mg Tablet 10's causes sleepiness and restlessness; do not drive unless alert.
  • Zonalta 8 mg Tablet 10's should not be given to children as safety and effectiveness have not been established.
  • Avoid consuming alcohol with Zonalta 8 mg Tablet 10's as it could lead to undesirable effects.
  • Keep your doctor updated on your medical condition and medications to rule out any potential side effects.

Drug-Drug Interactions

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No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

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Diet & Lifestyle Advise

  • Lifestyle adjustments and mood-management techniques can be beneficial.
  • Always maintain a healthy diet and exercise regularly.
  • Attend counselling regularly.
  • Practice meditation and yoga.
  • Maintain a consistent sleep schedule.
  • Avoid smoking and drinking alcohol.

Habit Forming

Not enough scientific literature available around this hence it is best to consult your physician

Therapeutic Class

PSYCHOTHERAPEUTICS

Zonalta 8 mg Tablet 10's Substitute

Substitutes safety advice
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Alcohol

Caution

Avoid alcohol consumption while taking Zonalta 8 mg Tablet 10's as it may increase dizziness and sleepiness.

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Pregnancy

Unsafe

Zonalta 8 mg Tablet 10's should not be administered to pregnant women as Zonalta 8 mg Tablet 10's falls under pregnancy category D.

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Breast Feeding

Unsafe

Women should be advised not to breastfeed throughout therapy and for three months following the final dosage of Zonalta 8 mg Tablet 10's.

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Driving

Unsafe

Zonalta 8 mg Tablet 10's causes sleepiness and tiredness or restlessness. Do not drive or operate machinery unless you are alert.

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Liver

Caution

If you have a history or evidence of any Liver-related diseases, inform the doctor before taking medicine. Your doctor will measure the benefits and potential risks before prescribing Zonalta 8 mg Tablet 10's.

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Kidney

Caution

If you have a history or evidence of any Kidney-related diseases, inform the doctor before taking medicine. Your doctor will measure the benefits and potential risks before prescribing Zonalta 8 mg Tablet 10's.

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Children

Unsafe

The Zonalta 8 mg Tablet 10's is not recommended for use on children under 18 because of insufficient data on efficacy and safety.

FAQs

Zonalta 8 mg Tablet 10's is used to treat or reduce the symptoms of manic episodes in bipolar I illness, with or without mixed characteristics (both highs and lows at the same time).

Zonalta 8 mg Tablet 10's contains Endoxifen, which acts in the neurological system by suppressing protein kinase C activity and so aids in the management of various brain chemicals that affect your moods, such as serotonin, norepinephrine, and dopamine.

Zonalta 8 mg Tablet 10's is indicated in adults for the acute treatment of manic episodes with or without mixed features (both highs and lows simultaneously) that happen with bipolar disorder.

You are not recommended to stop taking Zonalta 8 mg Tablet 10's even if you begin to feel better as it may cause recurring symptoms. Therefore, continue taking Zonalta 8 mg Tablet 10's for as long as it is suggested by a doctor.

Zonalta 8 mg Tablet 10's may cause stomach upset or diarrhoea. Do not take any medication to treat this condition without a doctor's notice. It does not require medical attention and will resolve gradually over time in most cases. However, you are advised to talk to your doctor if you experience these side effects persistently.

The side effects of Zonalta 8 mg Tablet 10's include headache, vomiting, insomnia (inability to sleep), diarrhoea, restlessness, or stomach upset. If these side effects persist or worsen, please consult your doctor.

Bipolar disorder also called as manic depression is a mental illness that causes unusual shifts in a person's mood, energy, concentration, and activity levels. It is marked by episodes of mood swings ranging from depressive lows to manic highs.

Zonalta 8 mg Tablet 10's is not recommended for use during pregnancy and breastfeeding. Therefore, if you are pregnant, planning pregnancy or are breastfeeding, inform your doctor before taking Zonalta 8 mg Tablet 10's.

Yes, Zonalta 8 mg Tablet 10's may cause eye problems, including visual disturbances or more serious retinopathy (damage to the retina of the eyes). If you experience such problems, consult your doctor.

Country of origin

India

Manufacturer/Marketer address

Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.
Other Info - ZON0131

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Veda MaddalaDoctor badge

Reviewed By

Veda Maddala

M Pharmacy

Last Updated

Sep 22, 2025 | 11:35 AM IST

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Reference

  1. https://zonalta.in/
  2. https://zonalta.in/wp-content/uploads/2021/03/10-4731-0-6004212-ZONALTA-PIL-1.pdf

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