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compositionComposition:PANTOPRAZOLE-40MG
prescription
Prescription Medicine
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Zotopan 40 mg Combipack Injection 1's is used in the treatment of Gastro-oesophageal reflux disease (GERD), duodenal/gastric ulcers, Zollinger-Ellison syndrome, heartburn, and erosive oesophagitis. It contains pantoprazole, which helps decrease the amount of acid in the stomach. Some of the common side effects include headache, dizziness, diarrhoea, nausea, vomiting, stomach pain, gas, joint pain, redness, and injection site reactions.

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Written By Veda Maddala , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
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More about the Product

Composition :

PANTOPRAZOLE-40MG

Manufacturer/Marketer :

Torin Pharmaceuticals Pvt Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-28

Return Policy :

Not Returnable

About Zotopan 40 mg Combipack Injection 1's

Zotopan 40 mg Combipack Injection 1's is primarily used to treat gastro-oesophageal reflux disease (GERD), heartburn, erosive oesophagitis, Zollinger-Ellison syndrome (a rare condition in which the pancreas causes excessive acid production leading to peptic ulcers) and other conditions caused by excessive acid in the stomach. GERD is a condition that occurs when stomach acid frequently flows back into the oesophagus. 

Zotopan 40 mg Combipack Injection 1's contains Pantoprazole, which blocks the action of the gastric proton pump that is responsible for the production of acid in the stomach. This reduces the amount of acid produced, heals the ulcers, and prevents the formation of new ulcers.

Common side effects of Zotopan 40 mg Combipack Injection 1's include headache, dizziness, diarrhoea, nausea, vomiting, stomach pain, gas, joint pain, redness, and swelling at the injection site. If the side effects persist or worsen, please consult a doctor.

Let your doctor know if you are sensitive or allergic to Zotopan 40 mg Combipack Injection 1's or other medications. Pregnant and breastfeeding women should consult their doctor before using Zotopan 40 mg Combipack Injection 1's. The name Zotopan 40 mg Combipack Injection 1's is not recommended for children under the age of five.

Uses of Zotopan 40 mg Combipack Injection 1's

Zotopan 40 mg Combipack Injection 1's is used to treat conditions caused by excessive stomach acid production. The detailed uses of Zotopan 40 mg Combipack Injection 1's are as follows:

  • Duodenal ulcers: Zotopan 40 mg Combipack Injection 1's promotes healing and reduces discomfort caused by ulcers in the small intestine.
  • Gastric ulcers: Zotopan 40 mg Combipack Injection 1's reduces stomach acid to heal and prevent recurrence of stomach ulcers.
  • Reflux oesophagitis: Zotopan 40 mg Combipack Injection 1's treats the inflammation and damage caused by acid reflux in the esophagus.
  • Erosive esophagitis: Zotopan 40 mg Combipack Injection 1's aids in healing the esophageal lining damaged due to excessive stomach acid.
  • Zollinger-Ellison syndrome: Zotopan 40 mg Combipack Injection 1's regulates the excessive acid production associated with Zollinger-Ellison syndrome.

Key Benefits

  • Zotopan 40 mg Combipack Injection 1's contains Pantoprazole, which is a proton pump inhibitor.
  • It blocks the action of the gastric proton pump that is responsible for the production of acid in the stomach.
  • This reduces the amount of acid produced, heals the ulcers, and prevents the formation of new ulcers.
  • It also relieves the symptoms of GERD, like heartburn, difficulty in swallowing, and persistent cough. Pantoprazole may also prevent oesophageal cancer.
Side effects of Zotopan 40 mg Combipack Injection
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
Here are the steps to manage Gastrointestinal Air and Swelling (GAS) caused by medication:
  • Tell your doctor about your GAS symptoms. They may change your medication regimen or prescribe additional drugs to help you manage them.
  • To manage GAS symptoms, eat a balanced diet of fibre, vegetables, and fruits.
  • Drink enough water throughout the day to avoid constipation and treat GAS symptoms.
  • Regular exercise like yoga and walking may help stimulate digestion and alleviate GAS symptoms.
  • Take probiotics only if your doctor advises, as they may help alleviate GAS symptoms by promoting gut health.
  • Take medication for GAS symptoms only if your doctor advises, as certain medications can interact with your existing prescriptions or worsen symptoms.
  • If symptoms persist, worsen, or are accompanied by severe abdominal pain, vomiting, or bleeding, seek immediate medical attention.
Here are the steps to manage Joint Pain caused by medication usage:
  • Please inform your doctor about joint pain symptoms, as they may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Your doctor may prescribe common pain relievers if necessary to treat joint discomfort.
  • Maintaining a healthy lifestyle is key to relieving joint discomfort. Regular exercise, such as low-impact sports like walking, cycling, or swimming, should be combined with a well-balanced diet. Aim for 7-8 hours of sleep per night to assist your body in repairing and rebuilding tissue.
  • Applying heat or cold packs to the affected joint can help reduce pain and inflammation.
  • Please track when joint pain occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • If your joint pain is severe or prolonged, consult a doctor to rule out any underlying disorders that may require treatment.
Here are the steps to manage the medication-triggered Cough:
  • Tell your doctor about the cough symptoms you're experiencing, which may be triggered by your medication.
  • Your doctor may adjust your treatment plan by changing your medication, adding new medications, or providing guidance on managing your cough symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Stay hydrated by drinking plenty of fluids, such as water, tea, or soup, to help thin out mucus and soothe your throat.
  • Get plenty of rest and engage in stress-reducing activities to help your body recover. If your cough persists or worsens, consult your doctor for further guidance.

Directions for Use

  • Follow your doctor's instructions on the dosage and timing of Zotopan 40 mg Combipack Injection 1's to ensure its safe and effective use.
  • Zotopan 40 mg Combipack Injection 1's will be administered by a healthcare professional in a hospital.
  • Do not self-administer this medication.

How Zotopan 40 mg Combipack Injection 1's Works

Zotopan 40 mg Combipack Injection 1's contains Pantoprazole. It blocks the action of the gastric proton pump that is responsible for the production of acid in the stomach. This reduces the amount of acid produced, heals the ulcers, and prevents the formation of new ulcers.
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Alcohol

Unsafe

Alcohol consumption may increase acid production in the stomach. It is advised to avoid alcohol intake to prevent any undesirable side effects of Zotopan 40 mg Combipack Injection 1's and further worsening of your condition.

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Pregnancy

Consult your doctor

It is advised to consult your doctor if you plan to conceive or are already pregnant before starting Zotopan 40 mg Combipack Injection 1's.

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Breast Feeding

Consult your doctor

It is not known if Zotopan 40 mg Combipack Injection 1's passes into breast milk. Please consult your doctor before taking Zotopan 40 mg Combipack Injection 1's if you are a nursing mother.

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Driving

Caution

Zotopan 40 mg Combipack Injection 1's may cause dizziness; hence drive or operate machinery only when you are alert.

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Liver

Consult your doctor

Let your doctor know if you have any history of liver diseases or hepatic impairment. Your doctor will weigh the benefits and potential risks before prescribing Zotopan 40 mg Combipack Injection 1's.

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Kidney

Consult your doctor

Let your doctor know if you have any history of kidney diseases. Your doctor will weigh the benefits and potential risks before prescribing Zotopan 40 mg Combipack Injection 1's.

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Children

Caution

Zotopan 40 mg Combipack Injection 1's is recommended for children above five years of age only when prescribed by a doctor.

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Heart

Safe if prescribed

Zotopan 40 mg Combipack Injection 1's is generally considered safe for patients with heart conditions when used as prescribed by your doctor. Please consult your doctor if you have any concerns regarding it.

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Geriatrics

Safe if prescribed

Zotopan 40 mg Combipack Injection 1's is generally considered safe for elderly patients. However, it is advisable to consult your doctor before receiving Zotopan 40 mg Combipack Injection 1's.

What if I have taken an overdose of Zotopan 40 mg Combipack Injection 1's

Since Zotopan 40 mg Combipack Injection 1's is administered by a healthcare professional, an overdose is unlikely to occur. However, seek medical attention if you experience any unusual symptoms.

Diet & Lifestyle Advise

  • Avoid smoking and alcohol consumption. Alcohol intake leads to increased production of stomach acid, thereby increasing acidity and heartburn.
  • Manage stress, eat healthily, drink plenty of water, exercise regularly, and get plenty of sleep.
  • Limit taking high fibre foods, foods and drinks that contain chocolate, alcohol, caffeine, fructose, or sorbitol, carbonated drinks, fried, and fatty foods.
  • Do not have large meals at a time; instead try having small and simpler meals at regular intervals, including fresh fruits and vegetables in your diet.
  • Practice yoga and recreation techniques to manage your emotional stress.
  • If you are lactose intolerant, avoid using dairy products since it can worsen your stomach discomfort.
  • If you cannot take dairy products, it is advised to include other calcium-rich foods like leafy greens, beans, nuts, and seeds.
  • Drink plenty of fluids to prevent dehydration.
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Have a query?

How Soon It Starts Working

  • The time required for Zotopan 40 mg Combipack Injection 1's to start to work: Zotopan 40 mg Combipack Injection 1's ideally shows its action within 15 minutes of administration. 
  • The time for which the effects of Zotopan 40 mg Combipack Injection 1's last: Zotopan 40 mg Combipack Injection 1's effect lasts upto 24 hours.

What if you forget to take Zotopan 40 mg Combipack Injection 1's

As this medicine is administered by a healthcare professional, the chances of missing a dose are less. However, if you have any concerns, contact your doctor.

Storage

• Store in a cool and dry place away from sunlight.• Keep out of sight and reach of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

  • Let your doctor know if you are sensitive to any of the components in Zotopan 40 mg Combipack Injection 1's.
  • Zotopan 40 mg Combipack Injection 1's should be used with caution and only under a doctor’s supervision if you have stomach/intestinal problems, liver, kidney or heart diseases, recent abdominal surgery, risk of bone fractures, and autoimmune diseases like lupus.
  • Long term treatment with Zotopan 40 mg Combipack Injection 1's may increase the risk of fractures of the hip, spine, and wrist.
  • Hence, inform your doctor if you have osteoporosis and bone-related problems.
  • Zotopan 40 mg Combipack Injection 1's may also cause low Vitamin B12 levels on long term usage.
  • Hence let your doctor know if you have Vitamin B12 deficiency before starting Zotopan 40 mg Combipack Injection 1's.
  • Let your doctor know if you are pregnant or a nursing mother before starting Zotopan 40 mg Combipack Injection 1's.
  • Zotopan 40 mg Combipack Injection 1's may cause dizziness; hence drive or operate machinery only when you are alert.
  • Avoid alcohol intake while using Zotopan 40 mg Combipack Injection 1's since it can increase acid production in the stomach.
  • Zotopan 40 mg Combipack Injection 1's is recommended for children above five years of age only when prescribed by a doctor.

Drug-Drug Interactions

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Drug-Drug Interaction: Zotopan 40 mg Combipack Injection 1's may interact with anti-HIV (atazanavir), antifungals (ketoconazole, itraconazole), anti-cancer drugs (methotrexate), heart-related medicines (digoxin), and water pills.

Drug-Food Interaction: Avoid fatty foods, alcohol, caffeine, and other triggering foods that can worsen your gastrointestinal problems.

Drug-Disease Interaction: Brief your medical history to the doctor if you have stomach/intestinal problems, liver, kidney or heart diseases, recent abdominal surgery, risk of bone fractures, autoimmune diseases like lupus, and Vitamin B12 deficiency before starting Zotopan 40 mg Combipack Injection 1's.

PantoprazoleRilpivirine
Critical
PantoprazolePazopanib
Severe

Drug-Drug Interactions

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PantoprazoleRilpivirine
Critical
How does the drug interact with Zotopan 40 mg Combipack Injection:
Co-administration of Rilpivirine is taken with Zotopan 40 mg Combipack Injection, can decrease the absorption and blood levels of Rilpivirine and make the medication less effective.

How to manage the interaction:
Taking Zotopan 40 mg Combipack Injection with Rilpivirine can lead to an interaction, please consult a doctor before taking it. Do not stop using any medications without talking to a doctor.
PantoprazolePazopanib
Severe
How does the drug interact with Zotopan 40 mg Combipack Injection:
Taking Zotopan 40 mg Combipack Injection with Pazopanib may reduce the effectiveness of pazopanib.

How to manage the interaction:
If you are supposed to take Zotopan 40 mg Combipack Injection and Pazopanib together, but can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
PantoprazoleMethotrexate
Severe
How does the drug interact with Zotopan 40 mg Combipack Injection:
Co-administration of Methotrexate with Zotopan 40 mg Combipack Injection can increase the levels and side effects of Methotrexate.

How to manage the interaction:
Although there is a possible interaction between Zotopan 40 mg Combipack Injection and methotrexate, you can take these medicines together if prescribed by a doctor. However, if you experience any symptoms such as nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, tiredness, weakness, or dizziness, consult a doctor. Do not stop using any medications without consulting a doctor.
PantoprazoleGefitinib
Severe
How does the drug interact with Zotopan 40 mg Combipack Injection:
Taking Gefitinib with Zotopan 40 mg Combipack Injection reduces the acidity level in the stomach and may interfere with the absorption of Gefitinib and reduce its effectiveness.

How to manage the interaction:
Taking Zotopan 40 mg Combipack Injection with Gefitinib together can possibly result in an interaction, it can be taken if your doctor has advised it. You are recommended to take gefitinib 12 hours before or 12 hours after Zotopan 40 mg Combipack Injection to help minimize the impact of the interaction. Do not discontinue the medication without consulting a doctor.
PantoprazoleDasatinib
Severe
How does the drug interact with Zotopan 40 mg Combipack Injection:
Taking Dasatinib with Zotopan 40 mg Combipack Injection may decrease the blood levels of Dasatinib and reduce its effectiveness.

How to manage the interaction:
Taking Zotopan 40 mg Combipack Injection with Dasatinib together can result in an interaction, but it can be taken if a doctor has advised it. In case of any unusual side effects, contact a doctor. Do not stop using any medications without a doctor's advice.
PantoprazoleAtazanavir
Severe
How does the drug interact with Zotopan 40 mg Combipack Injection:
Co-administration of Zotopan 40 mg Combipack Injection reduces stomach acid, decreases the absorption and blood levels of Atazanavir, and reduces its effectiveness.

How to manage the interaction:
Taking Zotopan 40 mg Combipack Injection with Atazanavir together can possibly result in an interaction, but it can be taken if a doctor has advised it. A doctor can recommend other options that won't cause any problems when taken together. Do not stop using any medications without a doctor's advice.
PantoprazoleNelfinavir
Severe
How does the drug interact with Zotopan 40 mg Combipack Injection:
Taking Nelfinavir with Zotopan 40 mg Combipack Injection may decrease the absorption and blood levels of Nelfinavir and reduce its effectiveness.

How to manage the interaction:
Taking Zotopan 40 mg Combipack Injection with Nelfinavir together can possibly result in an interaction, but it can be taken if a doctor has advised it. A doctor can recommend other options that won't cause any problems when taken together. Do not stop using any medications without a doctor's advice.
PantoprazoleDacomitinib
Severe
How does the drug interact with Zotopan 40 mg Combipack Injection:
Taking Zotopan 40 mg Combipack Injection can make Dacomitinib less effective by reducing its absorption in the body.

How to manage the interaction:
Taking Zotopan 40 mg Combipack Injection with Dacomitinib together can possibly result in an interaction, but it can be taken if a doctor has advised it. A doctor can recommend other options that won't cause any problems when taken together. Do not stop using any medications without a doctor's advice.
PantoprazoleErlotinib
Severe
How does the drug interact with Zotopan 40 mg Combipack Injection:
Taking Erlotinib with Zotopan 40 mg Combipack Injection may interfere with the absorption of Erlotinib into the bloodstream, and reduce its effectiveness.

How to manage the interaction:
Taking Zotopan 40 mg Combipack Injection with Erlotinib together can possibly result in an interaction, but it can be taken if a doctor has advised it. A doctor can recommend other options that won't cause any problems when taken together. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[GASTROINTESTINAL AGENTS]

FAQs

Zotopan 40 mg Combipack Injection 1's is used to treat stomach ulcers, gastro-oesophageal reflux disease (GERD), heartburn, erosive oesophagitis, and Zollinger-Ellison syndrome.
Zotopan 40 mg Combipack Injection 1's works by reducing the amount of acid produced in the stomach and thus relieves stomach ulcers, heartburn, GERD, and other gastrointestinal discomforts.
Please do not take Zotopan 40 mg Combipack Injection 1's for longer durations unless prescribed by the doctor. Taking Zotopan 40 mg Combipack Injection 1's on long-term may cause you to develop stomach growths known as fundic gland polyps. A regular check-up is advised if Zotopan 40 mg Combipack Injection 1's is prescribed for longer durations.
Zotopan 40 mg Combipack Injection 1's may cause bloating as a side effect with its regular use. You may experience tightness, fullness, or swelling of your stomach area. It is advised to avoid consuming wind/gas-producing foods like beans, onions, lactose-containing foods, and carbonated beverages. You can also try herbal teas like peppermint, coriander, fennel, turmeric, and chamomile. If you do not notice any improvement in your bloating, please seek medical advice.
Diarrhea might be a side-effect of Zotopan 40 mg Combipack Injection 1's. Drink lots of fluids and eat non-spicy foods if you experience diarrhea. If you find blood in stools (tarry stools) or experience excess diarrhea, consult your doctor. Prolonged intake of proton pump inhibitors like Zotopan 40 mg Combipack Injection 1's is linked with a greater risk of Clostridium difficile-associated diarrhea. If you develop diarrhea that does not improve, immediately consult a doctor.
On long term treatment, Zotopan 40 mg Combipack Injection 1's may increase the risk of fractures of the hip, spine, and wrist. Inform your doctor if you have osteoporosis, bone-related problems, or take any corticosteroids. Your doctor may suggest supplements like Calcium citrate and Vitamin D.
Zotopan 40 mg Combipack Injection 1's may cause low Vitamin B12 levels on long term usage. Your doctor may adjust the dose of Zotopan 40 mg Combipack Injection 1's accordingly and may suggest Vitamin B12 supplements if you are on long term treatment with Zotopan 40 mg Combipack Injection 1's.
Zotopan 40 mg Combipack Injection 1's should be used with caution and only under a doctor's supervision if you have any liver, kidney or heart diseases, stomach and intestinal problems, recent abdominal surgery, Vitamin B12 deficiency, risk of bone fractures, osteoporosis, and autoimmune diseases like lupus.

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Country of origin

India

Manufacturer/Marketer address

Kings House, Asha Nagar 2 Gate, Near Childrens Academy School, Thakur Complex, Kandival i (E) , Mumbai, Maharashtra, India - 400101
Other Info - ZOT0060

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