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  3. Zydiclo Gel 30gm

Zydiclo Gel 30gm, Pack of 1
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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Zydiclo Gel is used to relieve pain and inflammation associated with musculoskeletal disorders, strain, sprain, arthritis, contusions (bruises), post-traumatic pain, and low back pain. It contains diclofenac diethylamine, which works by blocking the effect of chemical messengers that cause pain and inflammation. In some cases, this medicine may cause side effects such as application site reactions like itching, irritation, redness, and a burning sensation.

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Composition :

DICLOFENAC DIETHYLAMINE-1.16%W/W

Manufacturer/Marketer :

Cadila Healthcare Ltd

Consume Type :

TOPICAL

Return Policy :

Not Returnable

Expires on or after :

About Zydiclo Gel

Zydiclo Gel is used to relieve pain and inflammation associated with musculoskeletal disorders, strain, sprain, arthritis, contusions (bruises), post-traumatic pain, and low back pain. Musculoskeletal pain could occur due to arthritis, osteoporosis, fractures, dislocations, problems with the bone structure or injury to the bones, joints, tendons, muscles, and ligaments.

Zydiclo Gel contains Diclofenac diethylamine, which works by blocking the effect of a chemical messenger known as cyclo-oxygenase (COX) enzymes that make another chemical, prostaglandin. By blocking the effect of COX enzymes, fewer prostaglandins are produced; this helps in reducing mild to moderate pain and inflammation at the injured or damaged site.

In some cases, you may experience common side effects such as application site reactions like itching, irritation, redness, and a burning sensation. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if the side effects persist or worsen.

Zydiclo Gel is for external use only. Notify your doctor if you have had any recent heart surgery. Consult a doctor before using Zydiclo Gel if you are pregnant or breastfeeding. Do not apply Zydiclo Gel to open wounds, cuts, scrapes, or damaged skin. Avoid using Zydiclo Gel if you are during the perioperative period in the setting of coronary artery bypass graft surgery.

Uses of Zydiclo Gel

Zydiclo Gel is used in the treatment of pain and inflammation of muscles and joints. The detailed uses of Zydiclo Gel are as follows: <br/> • Relief of muscle pain: Zydiclo Gel helps reduce pain caused by muscle strain, overuse, or mild injuries.<br/> • Treatment of joint inflammation: It reduces swelling, stiffness, and discomfort in joints affected by osteoarthritis or other inflammatory conditions.<br/> • Management of backache: Zydiclo Gel provides localised relief from lower or upper back pain.<br/> • Support in sprains and strains: Reduces pain and inflammation due to ligament or muscle injuries.<br/> • Relief of sports injuries: Zydiclo Gel is commonly used to treat minor injuries caused by physical exercise.<br/> • Control of soft tissue inflammation: It reduces inflammation in tendons, ligaments, and soft tissues, including tendinitis and bursitis. <br/>

Directions for Use

  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safe and effective use.
  • Apply a thin layer of Zydiclo Gel and gently massage it into the skin until absorbed.
  • Zydiclo Gel is only for external use. Avoid contact of the Zydiclo Gel with the nose, mouth or eyes. In case of accidental contact with these areas, rinse with water thoroughly.

Medicinal Benefits

Zydiclo Gel is used to relieve pain and inflammation associated with musculoskeletal disorders, strain, sprain, arthritis, and low back pain. Zydiclo Gel works by blocking the effect of a chemical messenger known as cyclo-oxygenase (COX) enzymes that make other chemical prostaglandins. By blocking the effect of COX enzymes, fewer prostaglandins are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site.

How Zydiclo Gel Works

Zydiclo Gel contains Diclofenac diethylamine, which works by blocking the effect of a chemical messenger known as cyclo-oxygenase (COX) enzymes that make another chemical, prostaglandin. By blocking the effect of COX enzymes, fewer prostaglandins are produced; this helps in reducing mild to moderate pain and inflammation at the injured or damaged site.

Storage

• Store in a cool and dry place away from sunlight.• Keep Zydiclo Gel out of reach and sight of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if I have taken an overdose of Zydiclo Gel

Though overdose is unlikely due to low systemic absorption, it is advised to avoid exceeding the recommended dose. Seek immediate medical attention if you experience any unusual symptoms.

Drug Warnings

Do not use Zydiclo Gel if you are allergic to any of its contents, if you are hypersensitive to NSAIDs, or if you have kidney failure. Avoid using Zydiclo Gel if you are during the perioperative period in the setting of coronary artery bypass graft surgery. Zydiclo Gel may increase the risk of a fatal heart attack or stroke. So, if you have had any recent heart surgery, do not use Zydiclo Gel. Inform your doctor if you have peptic ulcers, heart surgery, high blood pressure, high cholesterol, diabetes, stomach ulcers, bleeding problems, asthma, fluid retention, inflammatory bowel disease, kidney or liver problems. Consult a doctor if you are pregnant or breastfeeding.

Drug-Drug Interactions

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No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

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Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

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Diet & Lifestyle Advise

  • Physical activity helps in strengthening muscles and relieves joint stiffness. Gentle activities like 20-30 minutes of walking or swimming would be helpful.
  • Performing yoga may also help improve joint flexibility and pain management.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Get adequate sleep, as resting the muscles can help in reducing inflammation and swelling.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
  • Acupuncture, massage and physical therapy may also be helpful.
  • Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.
  • Foods containing flavonoids help in reducing inflammation. These include soy, berries, broccoli, grapes and green tea.
  • Avoid smoking and alcohol consumption.

Habit Forming

No

Therapeutic Class

ANALGESICS

Zydiclo Gel Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Caution

Avoid alcohol consumption as it might increase the risk of stomach bleeding.

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Pregnancy

Caution

Please consult your doctor if you have any concerns regarding this; your doctor will prescribe only if the benefits outweigh the risks. Zydiclo Gel should not be used during the last trimester of pregnancy.

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Breast Feeding

Caution

Consult your doctor if you are breastfeeding; your doctor will decide whether Zydiclo Gel can be used by breastfeeding mothers or not. If you are breastfeeding, avoid applying Zydiclo Gel on your breast.

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Driving

Not applicable

Zydiclo Gel is unlikely to affect your ability to drive.

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Liver

Consult your doctor

Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Please consult your doctor if you have kidney impairment or any concerns regarding this. Avoid using Zydiclo Gel if you have kidney failure.

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Children

Consult your doctor

If you have any concerns regarding the use of Zydiclo Gel for children, please consult a doctor.

Have a query?

FAQs

Zydiclo Gel is used to relieve pain and inflammation associated with musculoskeletal disorders, strain, sprain, arthritis, contusions (bruises), post-traumatic pain, and low back pain.

Zydiclo Gel works by blocking the effect of chemical messengers that cause pain and inflammation at the injured or damaged site. Thereby, Zydiclo Gel helps in providing relief from pain.

Zydiclo Gel is used to reduce and relieve pain and inflammation associated with osteoarthritis. It is a joint disease in which the two ends of the joints come together due to the breakdown of a protective covering called cartilage.

Avoid concomitant use of Zydiclo Gel with other topical products such as cosmetics, sunscreens, lotions, moisturisers, insect repellent creams, and other gels.

Do not apply external heat or cover the treated skin with dressings after applying Zydiclo Gel. Covering the skin or applying heat might increase the amount of drugs absorbed into the skin, leading to unpleasant side effects.

Do not apply Zydiclo Gel on wounds, skin injuries, irritated skin, skin abrasions, rashes, and infections. Apply Zydiclo Gel on healthy skin only.

Avoid using Zydiclo Gel for longer durations unless prescribed by the doctor. The duration depends on the response to the treatment. If your condition does not improve despite using Zydiclo Gel for 7 days, consult a doctor.

Zydiclo Gel is usually applied up to 4 times a day. However, the frequency of application may vary depending on the specific condition being treated. Always follow the recommended dosage instructions provided by your doctor or pharmacist and consult them if you have any concerns.

The side effects of Zydiclo Gel are typically mild and limited to the application site. Common side effects include itching, redness, irritation, and burning sensation. Most of these side effects are temporary and resolve on their own over time. However, if any of these side effects persist or worsen, it's essential to consult your doctor for further guidance.

Zydiclo Gell is generally considered safe when used as directed by your doctor for short-term relief of pain and inflammation in conditions like muscle strains, sprains, and arthritis. However, it's essential to use it responsibly and avoid applying it to broken or irritated skin, near the eyes, or using it excessively.

Zydiclo Gel is not suitable for everyone. You should avoid using it if you're allergic to its ingredients, NSAIDs, or have kidney failure. Additionally, it's not recommended after recent heart surgery or during the perioperative period of coronary artery bypass graft surgery. Individuals with heart conditions, asthma, ulcers, or liver and kidney issues should consult a doctor before use. Furthermore, pregnant or breastfeeding women and children under 14 years old should consult a doctor before using Zydiclo Gel.

Zydiclo Gel should be used with caution during pregnancy. It's essential to consult your doctor if you have any concerns. Your doctor will prescribe this medication only if the benefits outweigh the risks. Notably, it should not be used during the last trimester of pregnancy.

The duration of using Zydiclo Gel varies depending on the condition being treated and individual factors. It's essential to follow your doctor's instructions and only use it for the recommended period. Typically, Zydiclo Gel is used for short-term pain relief, and long-term use should be avoided unless your doctor advises.

Country of origin

India

Manufacturer/Marketer address

Sarkhej-Dholka Road, Bhat, Ahmedabad-382 210, INDIA.
Other Info - ZYD0007

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Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 21, 2025 | 12:07 PM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://www.efda.gov.et/wp-content/uploads/2023/08/Diclofenac-diethylamine-1-ww-gel_Remethan_Remedica-Ltd.pdf
  2. https://www.mayoclinic.org/drugs-supplements/diclofenac-topical-application-route/description/drg-20063434
  3. https://medlineplus.gov/druginfo/meds/a611002.html

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