Apollo
logo
0

Welcome User

Login/Sign Up

Home
Buy Medicines
Lab Tests
Doctor Consult
Circle Membership
insurance
Blogs
Contact Us
Privacy Policy
Return & Refunds
Need Help
Terms and Conditions
Select Delivery Location
compositionComposition:FLURBIPROFEN-0.03%W/V
prescription
Prescription Medicine
info
image icons

Zyflur 0.03% Eye Drop 5 ml contains flurbiprofen which is an NSAID (Non-Steroidal Anti-Inflammatory Drugs) medicine. It is used to control eye inflammation before and after eye surgery (such as cataract removal) and laser surgery. This medicine helps prevent pupil of the eye from narrowing. It also prevents intraoperative miosis (decreased pupil size) during surgery.

Read more
Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
OffersOffers & Discounts

Get Free delivery (₹99) with circle icon

Join Circle
coupon
Get 18% Off with Coupons
coupon
Extra 10% Off with Bank Offers
bank offer
bank offer
bank offer

More about the Product

Composition :

FLURBIPROFEN-0.03%W/V

Manufacturer/Marketer :

Zytras Life Sciences Pvt Ltd

Consume Type :

Ophthalmic

Expires on or after :

Dec-28

Return Policy :

Not Returnable

About Zyflur 0.03% Eye Drop 5 ml

Zyflur 0.03% Eye Drop 5 ml is a specialised eye drop used primarily during and after eye surgeries, such as cataract removal. Its medical purpose is to prevent the pupil from shrinking during the procedure and to manage post-surgical swelling and discomfort. By targeting localised inflammation, it helps support a safe surgical process and a smoother recovery.

To achieve the best results, you must use Zyflur 0.03% Eye Drop 5 ml exactly at the times prescribed by your eye specialist, as consistency is key to controlling inflammation. Since these are eye drops, you will apply them directly to the affected eye, and they are not affected by food intake. Practicing proper eye rest and avoiding bright lights after surgery can further assist your recovery.

While using this medicine, you might experience mild, temporary stinging or watery eyes. However, if you experience severe eye pain, sudden changes in your vision, or signs of an allergic reaction, you must consult your doctor immediately.

Do not take this if you have a known allergy to aspirin or other nonsteroidal anti-inflammatory drugs (NSAIDs). It is also important to talk to your doctor before starting this medicine if you have a history of bleeding tendencies or active eye infections.

This medication can interact with other eye drops or blood thinners, which may increase your risk of bleeding or slow down healing. If you are pregnant, breastfeeding, or managing other chronic health conditions, talk to your doctor or pharmacist to ensure this treatment is safe for you.

Uses of Zyflur 0.03% Eye Drop 5 ml

Your doctor may prescribe Zyflur 0.03% Eye Drop 5 ml to treat the following conditions:

  • Preventing pupil constriction during surgery: Zyflur 0.03% Eye Drop 5 ml helps keep the pupil wide and stable during cataract procedures, allowing the surgeon to operate safely.
  • Reducing post-operative eye inflammation: Zyflur 0.03% Eye Drop 5 ml treats redness, swelling, and deep-tissue irritation in the eye following surgical procedures.

Key Benefits

Zyflur 0.03% Eye Drop 5 ml helps reduce post-surgical pain and inflammation while supporting a smooth recovery after eye surgery.

  • Relieves post-surgical pain: Helps reduce pain and discomfort after eye surgery, making the recovery period more comfortable.
  • Reduces inflammation and swelling: Controls inflammation in the eye, helping protect delicate eye tissues and promote faster healing.
  • Supports a smoother recovery: By managing pain and inflammation early, it helps you return to your normal daily activities more comfortably.
  • Maintains pupil dilation during surgery: Helps keep the pupil dilated during certain eye procedures, allowing the surgeon better visibility and reducing the risk of surgical complications.
  • Protects long-term eye health: Early control of inflammation helps minimize tissue damage, supporting clearer vision and a healthier recovery.

Directions for Use

  • Zyflur 0.03% Eye Drop 5 ml is typically used 1-2 times a day, or as prescribed by your healthcare provider, based on the severity of the condition.
  • Before using eye drops, wash your hands thoroughly. Then, tilt your head back, gently pull down your lower eyelid to create a small pocket, and drop the prescribed number of drops into the affected eye. Close your eye and gently press the corner of your eye near the nose for 1-2 minutes to prevent the drops from draining out.
  • Avoid touching the dropper to any surface, including your eyes, to prevent contamination.

How Zyflur 0.03% Eye Drop 5 ml Works

Zyflur 0.03% Eye Drop 5 ml contains flurbiprofen which belongs to a class of medications called nonsteroidal anti-inflammatory drugs (NSAIDs). It works by blocking the action of specific natural enzymes in the body called cyclooxygenase (COX). These enzymes are responsible for producing prostaglandins, which are the chemical messengers that cause pain, swelling, and pupil constriction when tissue is stressed or injured. By preventing the production of these prostaglandins directly in the eye tissue, Zyflur 0.03% Eye Drop 5 ml keeps the pupil dilated during surgical manipulation and halts the inflammatory cascade. This localized action ensures that swelling and discomfort are managed directly at the source without affecting the rest of your body.
bannner image

Alcohol

Caution

There is limited information on how alcohol consumption affects Zyflur 0.03% Eye Drop 5 ml. Please consult your doctor before using Zyflur 0.03% Eye Drop 5 ml.

bannner image

Pregnancy

Caution

If you plan to conceive or are already pregnant, inform your doctor before using Zyflur 0.03% Eye Drop 5 ml. Your doctor may prescribe this medicine if the benefits outweigh the risks.

bannner image

Breast Feeding

Caution

If you are breastfeeding, please consult your doctor before using Zyflur 0.03% Eye Drop 5 ml.

bannner image

Driving

Caution

Zyflur 0.03% Eye Drop 5 ml may cause side effects like blurry vision, affecting your driving ability. Do not drive or operate machinery in such cases. Drive only when you are alert and have a clear vision

bannner image

Liver

Caution

Let your doctor know if you have any history of liver diseases before instilling Zyflur 0.03% Eye Drop 5 ml.

bannner image

Kidney

Caution

Let your doctor know if you have any history of kidney diseases before instilling Zyflur 0.03% Eye Drop 5 ml.

bannner image

Children

Caution

Zyflur 0.03% Eye Drop 5 ml can be used in children only when advised by a doctor.

bannner image

Heart

Caution

Zyflur 0.03% Eye Drop 5 ml may increase the risk of heart problems. Therefore, please inform your doctor if you have any heart-related problems before using Zyflur 0.03% Eye Drop 5 ml.

bannner image

Geriatrics

Consult your doctor

Please consult a doctor before administering Zyflur 0.03% Eye Drop 5 ml to geriatric patients. Your doctor will prescribe Zyflur 0.03% Eye Drop 5 ml if the benefits outweigh the risks.

What if I have taken an overdose of Zyflur 0.03% Eye Drop 5 ml

An overdose of this medication is unlikely when used as directed. However, if you accidentally put too many drops in your eye, flush the eye immediately with plenty of clean, lukewarm water. If Zyflur 0.03% Eye Drop 5 ml is swallowed, or if you suspect a serious overdose, seek immediate medical attention or contact a poison control center right away.

Diet & Lifestyle Advise

  • Protect your eyes: Wear dark sunglasses outdoors to protect your healing eyes from bright sunlight and wind, which can trigger further irritation.
  • Avoid rubbing your eyes: Do not touch or rub your eyes, as this can introduce bacteria or disrupt the delicate surgical healing process.
  • Limit strenuous activities: Avoid heavy lifting, bending over from the waist, or intense exercise for the period recommended by your doctor, as these activities can increase pressure inside the eye.
  • Prevent water contamination: Avoid splashing water directly into your face while showering, and stay out of swimming pools and hot tubs until your doctor says it is safe.
health query

Have a query?

How Soon It Starts Working

The time required for Zyflur 0.03% Eye Drop 5 ml to start to work: The onset time of Zyflur 0.03% Eye Drop 5 ml has not been clinically established. The time for which the effects of Zyflur 0.03% Eye Drop 5 ml last: The duration of Zyflur 0.03% Eye Drop 5 ml’s effect is clinically not established.

What if you forget to take Zyflur 0.03% Eye Drop 5 ml

If you miss a dose of Zyflur 0.03% Eye Drop 5 ml, apply the missed drop as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed one and return to your regular schedule. Do not apply a double dose to make up for a missed one.

Storage

• Store Zyflur 0.03% Eye Drop 5 ml at controlled room temperature, ideally between 15°C and 25°C.

Drug Warnings

  • Check the solution: Inspect the bottle before every use; do not use the drops if the liquid is cloudy, discolored, or contains visible particles.
  • Keep the dropper sterile: Never touch the tip of the dropper to your eye, fingers, or any other surface to avoid bacterial contamination.
  • Remove contact lenses: Do not wear contact lenses while using Zyflur 0.03% Eye Drop 5 ml unless your eye doctor has specifically told you it is safe to do so.
  • Spacing other eye drops: Always wait at least 5 to 10 minutes between using Zyflur 0.03% Eye Drop 5 ml and any other prescribed eye drops to prevent washing out either medication.
  • Monitor healing: Keep all post-surgical follow-up appointments so your doctor can monitor your eye pressure and healing progress.

Drug-Drug Interactions

verifiedApollotooltip
  • Blood thinners: Using Zyflur 0.03% Eye Drop 5 ml alongside oral blood thinners (like warfarin) or antiplatelet drugs may increase the risk of bleeding in the eye tissue.
  • Steroid eye drops: Combining this medicine with ophthalmic corticosteroids may slow down the healing process of the eye surface.
FlurbiprofenKetorolac tromethamine
Critical
FlurbiprofenKetorolac
Critical

Drug-Drug Interactions

Login/Sign Up

FlurbiprofenKetorolac tromethamine
Critical
How does the drug interact with Zyflur 0.03% Eye Drop 5 ml:
Taking Ketorolac with Zyflur 0.03% Eye Drop 5 ml can increase the risk of side effects in the gastrointestinal tract such as inflammation, bleeding, ulceration.

How to manage the interaction:
Taking Zyflur 0.03% Eye Drop 5 ml with Ketorolac tromethamine is not recommended, but it can be taken if your doctor has advised it. However, if you experience dizziness, lightheadedness red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache and weakness contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
FlurbiprofenKetorolac
Critical
How does the drug interact with Zyflur 0.03% Eye Drop 5 ml:
Taking Ketorolac with Zyflur 0.03% Eye Drop 5 ml can increase the risk of side effects in the gastrointestinal tract such as inflammation, bleeding, ulceration.

How to manage the interaction:
Taking Zyflur 0.03% Eye Drop 5 ml with Ketorolac is not recommended, but it can be taken if your doctor has advised it. However, if you experience dizziness, lightheadedness red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache and weakness contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
FlurbiprofenIodamide
Severe
How does the drug interact with Zyflur 0.03% Eye Drop 5 ml:
Using Iodamide with Zyflur 0.03% Eye Drop 5 ml can increase the risk of kidney problems.

How to manage the interaction:
Taking Zyflur 0.03% Eye Drop 5 ml with Iodamide together can possibly result in an interaction, but it can be taken if your doctor has advised it. Your doctor can recommend other options that won't cause any problems when taken together. Do not stop using any medications without first talking to your doctor.
FlurbiprofenApixaban
Severe
How does the drug interact with Zyflur 0.03% Eye Drop 5 ml:
Coadministration of Zyflur 0.03% Eye Drop 5 ml and Apixaban co-administration may raise the risk of bleeding.

How to manage the interaction:
Even though combining Zyflur 0.03% Eye Drop 5 ml and Apixaban may cause an interaction, it is still possible to take it if your doctor advises you to. Consult a doctor if you experience symptoms like blood in your urine or stool (or a black stool), severe bruising, prolonged nosebleeds, feeling dizzy or lightheaded, weakness or severe headache, vomiting blood or coughing up blood, heavy menstrual bleeding (in women), difficulty breathing, or chest pain. Without consulting a doctor, never stop taking any medications.
FlurbiprofenAdefovir dipivoxil
Severe
How does the drug interact with Zyflur 0.03% Eye Drop 5 ml:
Co-administration of Zyflur 0.03% Eye Drop 5 ml with adefovir dipivoxil can increase the risk of kidney problems.

How to manage the interaction:
Although there is a interaction between Zyflur 0.03% Eye Drop 5 ml with adefovir dipivoxil, but can be taken together if prescribed by a doctor. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
FlurbiprofenLithium
Severe
How does the drug interact with Zyflur 0.03% Eye Drop 5 ml:
Co-administration of Zyflur 0.03% Eye Drop 5 ml with Lithium may significantly increase the blood levels of lithium.

How to manage the interaction:
There may be a possibility of interaction between Zyflur 0.03% Eye Drop 5 ml and Lithium, but it can be taken if prescribed by a doctor. However, if you experience drowsiness, dizziness, confusion, loose stools, vomiting, muscle weakness, muscle incoordination, shaking of hands and legs, blurred vision, ringing in the ear, excessive thirst and increased urination contact your doctor immediately. Do not stop using any medications without a doctor's advice.
FlurbiprofenKetoprofen
Severe
How does the drug interact with Zyflur 0.03% Eye Drop 5 ml:
Taking Zyflur 0.03% Eye Drop 5 ml with Ketoprofen can increase the risk of side effects.

How to manage the interaction:
Co-administration of Zyflur 0.03% Eye Drop 5 ml with Ketoprofen can possibly result in an interaction, but it can be taken if your doctor has advised it. If you're having any of these symptoms like stomach pain, bleeding, or feeling dizzy, it's important to contact your doctor right away. They may be able to recommend other options that won't cause these problems. Remember to reach out to your doctor if you experience any unusual symptoms. Do not discontinue any medications without first consulting your doctor.
FlurbiprofenWarfarin
Severe
How does the drug interact with Zyflur 0.03% Eye Drop 5 ml:
Taking Warfarin with Zyflur 0.03% Eye Drop 5 ml can increase the risk of bleeding.

How to manage the interaction:
Although taking Zyflur 0.03% Eye Drop 5 ml and Warfarin together can possibly result in an interaction, they can be taken together if prescribed by a doctor. However, if you experience any signs and symptoms of unusual bleeding, like blood in urine, bruising, coughing up or vomiting blood that looks like coffee grounds, or having a severe headache, consult your doctor immediately. Do not stop using any medications without consulting a doctor.
FlurbiprofenDiclofenac
Severe
How does the drug interact with Zyflur 0.03% Eye Drop 5 ml:
Co-administration use of Diclofenac with Flubiprofen may increase the risk of stomach bleeding and ulcers.

How to manage the interaction:
There is a possibility of interaction between Diclofenac and Flubiprofen but they can be taken together if your doctor has prescribed them. Consult your doctor immediately if you experience any symptoms like Nausea, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, burning in stomach, acidity, severe headache and weakness. Do not stop using any medications without first talking to your doctor.
FlurbiprofenIodixanol
Severe
How does the drug interact with Zyflur 0.03% Eye Drop 5 ml:
Coadministration of Zyflur 0.03% Eye Drop 5 ml with Iodixanol can increase the risk of kidney problems.

How to manage the interaction:
Co-administration of Zyflur 0.03% Eye Drop 5 ml with Iodixanol can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm contact your doctor immediately. Do not discontinue any medications without consulting your doctor.

Drug-Food Interactions

verifiedApollotooltip

No clinically significant food interactions are known with Zyflur 0.03% Eye Drop 5 ml when used as directed.

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

Login/Sign Up

All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTI- INFLAMMATORY AGENTS]

FAQs

Zyflur 0.03% Eye Drop 5 ml is used to control eye inflammation before and after eye surgery (such as cataract removal) and laser surgery. It also prevents intraoperative miosis (decreased pupil size) during surgery.
Zyflur 0.03% Eye Drop 5 ml consists of Flurbiprofen, which inhibits prostaglandins, and maintains intraoperative pupil dilation. It prevents the pupil of the eye from narrowing, thus making it easier to perform eye surgery.
Avoid contact of the tip of the dispensing container with fingers, eyes, and eyelids when you use any eye formulation to prevent contamination of the medicine.
Zyflur 0.03% Eye Drop 5 ml should be used for babies only if prescribed by a doctor. Do not give any medicine to babies without consulting a pediatrician.
Zyflur 0.03% Eye Drop 5 ml may cause temporary blurred vision immediately after application. Do not drive, operate machinery, or perform tasks requiring clear vision until your vision has returned to normal. If blurred vision persists or worsens, contact your doctor.
No, Zyflur 0.03% Eye Drop 5 ml need not be refrigerated and can be stored at room temperature
No, Zyflur 0.03% Eye Drop 5 ml is not an antibiotic or a steroid. It belongs to the class of medicines called NSAIDs (Non-steroidal Anti Inflammatory Drugs).
Zyflur 0.03% Eye Drop 5 ml relieves eye pain and inflammation after surgery. However, it should be used only if advised by a doctor.
Let your doctor know if you are allergic to Zyflur 0.03% Eye Drop 5 ml or any other medications. Also, inform them if you are pregnant, breastfeeding, or have a history of allergies (especially to NSAIDs), asthma, viral eye infections, or issues with bleeding and clotting before starting Zyflur 0.03% Eye Drop 5 ml.
If Zyflur 0.03% Eye Drop 5 ml are prescribed for a condition linked to long-term pain, continue using them as directed by your doctor. For short-term pain, they can be stopped once your pain is relieved. Following your doctor’s advice.
Zyflur 0.03% Eye Drop 5 ml are generally safe when used in the dose and duration advised by a doctor. Do not use more than the recommended dose
Zyflur 0.03% Eye Drop 5 ml may cause side effects such as stinging or burning sensation of the eyes, and an increase or decrease in the size of the pupil, redness of the eye, and temporary blurred vision. If these side effects persist or worsen, consult your doctor.
Unless your eye doctor specifically tells you otherwise, do not wear contact lenses while using Zyflur 0.03% Eye Drop 5 ml. Remove your contact lenses before applying the drops and wash your hands before and after use to avoid contamination. Your doctor will advise you when it is safe to wear your lenses again.
A brief, mild stinging or burning sensation is very common immediately after applying Zyflur 0.03% Eye Drop 5 ml. This usually passes within a minute or two. However, if the stinging is severe, gets worse, or is accompanied by swelling or redness, wash your eye with clean water and contact your doctor.
You should not use Zyflur 0.03% Eye Drop 5 ml if you have a known severe allergy or asthma triggered by aspirin or other nonsteroidal anti-inflammatory drugs (NSAIDs). Doing so could cause an allergic reaction or breathing issues. Talk to your doctor or pharmacist about alternative options.
Once opened, eye drop bottles are susceptible to bacterial contamination. You should typically discard any remaining liquid in your bottle of Zyflur 0.03% Eye Drop 5 ml 4 weeks after opening, or as instructed by your pharmacist. Never use the drops beyond the printed expiration date.
If you are pregnant or breastfeeding, you should consult your doctor before using Zyflur 0.03% Eye Drop 5 ml. While eye drops act locally, some of the medicine can still enter your bloodstream, and your doctor will help weigh the benefits against any potential risks.
Use Zyflur 0.03% Eye Drop 5 ml exactly as prescribed by your doctor. The dosing schedule depends on whether you are using it before or after eye surgery. Do not use it more or less often than prescribed. If you are unsure about your dosing schedule or do not notice improvement, consult your doctor.
Yes. If you are using other eye drops or ointments, wait at least 5–10 minutes between each medication to prevent one from washing away the other. Apply eye drops before eye ointments. Follow your doctor's instructions for your complete eye treatment schedule.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. WebMD Medical Reference Review Board. Details Drug and Treatment Monograph. Atlanta, GA: WebMD; 2026. [Accessed on 02 Jun. 2026]Check here
  2. Drugs.com Clinical Review Team. Flurbiprofen Ophthalmic Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026]Check here
  3. Electronic Medicines Compendium (EMC). Pil.1343 Patient Information Leaflet (PIL). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026]Check here
  4. Flurbiprofen Flurbiprofen. [Accessed on 02 Apr. 2019]Check here
  5. Flurbiprofen Sodium Flurbiprofen Sodium. [Accessed on 10 Feb. 2026]Check here
  6. Ahuja M, Dhake AS, Sharma SK, Majumdar DK. Topical ocular delivery of NSAIDs. NIH National Library of Medicine, National Center for Biotechnology Information. PubMed Central. June 2008. [Accessed on 21st July 2022].Check here

Country of origin

INDIA

Manufacturer/Marketer address

Plot No.160 Hsiidc, Ind. Area, Sector-3, Karnal - 132001, Haryana (India)
Other Info - ZYF0038
whatsapp Floating Button
Buy Now