Menopause Treatment Options
The goal of treatment is to reduce symptom burden and protect long-term health. No single approach works for everyone, and the right choice depends on your medical history, symptom severity, and personal preferences. Always discuss options with a qualified clinician.
Hormone Replacement Therapy
Hormone replacement therapy (HRT) is the most effective medical treatment for moderate-to-severe menopause symptoms, particularly menopause hot flashes and genitourinary symptoms. It works by supplementing the oestrogen the ovaries no longer produce. Women who have a uterus also take a progestogen alongside oestrogen to protect the uterine lining.
HRT is available in several forms:
- Oral tablets taken daily.
- Transdermal patches, gels, or sprays applied to the skin, which deliver oestrogen without the first-pass liver effect.
- Vaginal creams, rings, or pessaries for localised genitourinary symptoms, with minimal systemic absorption.
The balance of benefits and risks is generally favourable for healthy women under 60 or within 10 years of menopause onset. Current evidence suggests that for this group, HRT reduces hot flashes, improves sleep, prevents bone loss, and may reduce the risk of cardiovascular disease when started early in the menopause transition.
Report adverse events related to any hormone therapy to your healthcare provider or the relevant regulatory authority.
Non-Hormonal Medications
For women who cannot or choose not to use hormone therapy, several non-hormonal prescription options exist.
- Certain antidepressants (selective serotonin reuptake inhibitors and serotonin-norepinephrine reuptake inhibitors) can meaningfully reduce hot flash frequency and intensity.
- Gabapentin, a nerve pain medicine, is sometimes prescribed for night sweats and sleep disruption.
- Clonidine, a blood pressure medicine, may help some women with flushing.
- A newer class of drugs targeting the neurokinin B pathway offers non-hormonal relief specifically for hot flashes. Ask your doctor whether this option is available and suitable for you.
All prescription medicines carry potential side effects. Never start or stop a medication without medical guidance.
Over-the-Counter and Complementary Approaches
Vaginal moisturisers and lubricants can relieve dryness safely for most women. Some women turn to phytoestrogen supplements derived from soy or red clover. Evidence for these is mixed; discuss with your doctor before use, particularly if you have a hormone-sensitive condition.