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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Amortive 0.25%W/W Cream is used to treat fungal nail infections. It contains Amorolfine, which works by stopping the production of a chemical called ergosterol in fungi that causes nail infections. Without ergosterol, the fungus cannot survive. As a result, it kills infection-causing fungi. It may cause common side effects, such as dry skin, itching, redness, or a burning sensation on the skin. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Whats That

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Synonym :

AMOROLFINE HYDROCHLORIDE

Composition :

AMOROLFINE-0.25%W/W

Manufacturer/Marketer :

Rockmed Pharma Pvt Ltd

Consume Type :

TOPICAL

Return Policy :

Not Returnable

Expires on or after :

About Amortive 0.25%W/W Cream

Amortive 0.25%W/W Cream belongs to a class of drugs called 'antifungal' primarily used to treat fungal nail infections. Fungal infection occurs when a fungus invades and affects the tissue on the skin.  Symptoms of a fungal infection include skin rash, irritation, redness, and scaling of the skin.  

Amortive 0.25%W/W Cream contains 'Amorolfine' that works by stopping producing a chemical called 'ergosterol' in fungi that causes nail infection. Without ergosterol, the fungus cannot survive. As a result, infection-causing fungi die. 

Use Amortive 0.25%W/W Cream as suggested by your doctor. Common side effects of Amortive 0.25%W/W Cream may include dry skin, itching, redness, or burning sensation of the skin. Most of these side effects of Amortive 0.25%W/W Cream do not require medical attention and typically resolve on their own over time. However, if the side effects persist or worsen, please consult your doctor.

If you are pregnant or breastfeeding, it is recommended to consult a doctor before using Amortive 0.25%W/W Cream. If you use Amortive 0.25%W/W Cream in topical form, avoid smoking or going near naked flames as Amortive 0.25%W/W Cream catches fire and burns easily. If you are using any steroidal cream, lotion or ointment, inform your doctor before taking Amortive 0.25%W/W Cream to adjust the dose.

Uses of Amortive 0.25%W/W Cream

Amortive 0.25%W/W Cream is used in the treatment of Fungal nail and skin infections. The detailed uses of Amortive 0.25%W/W Cream are as follows:
• Manages athlete’s foot (Tinea pedis): Amortive 0.25%W/W Cream treats fungal infections between toes.
• Addresses cutaneous candidiasis: Amortive 0.25%W/W Cream helps with yeast infections on the skin.
• Treats Pityriasis versicolor: Amortive 0.25%W/W Cream reduces discoloured patches caused by fungal overgrowth.

Directions for Use

  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safe and effective use.
  • File the infected area of the nail. Then, gently clean the nail surface. Use the spatula to scoop some lacquer from the bottle. Apply the medicine evenly over the entire nail surface. Again, wash the spatula and keep it for reuse.
  • For external use only. If Amortive 0.25%W/W Cream comes into contact with the eyes, nose, or mouth, rinse with water immediately.

Medicinal Benefits

Amortive 0.25%W/W Cream is an antifungal that is primarily used to treat fungal infections of nails and skin such as ringworm, jock itch and athlete’s foot, seborrheic dermatitis (dry, flaky skin on face, scalp, chest, upper back, or ears) and pityriasis (a type of skin rash that causes scaly, discoloured patches on chest, back, legs and arms). The fungal cell membranes are essential for their survival, as they prevent unwanted substances from entering the cells and stop the leakage of cell contents. Amortive 0.25%W/W Cream causes holes in the fungal cell membranes and kills fungi. Therefore, it clears fungal infections and provides relief from the symptoms of skin irritation, including cracking, burning, scaling, and itching, caused by these infections.

How Amortive 0.25%W/W Cream Works

Amortive 0.25%W/W Cream contains 'Amorolfine' that works by stopping producing a chemical called 'ergosterol' in fungi that causes nail infection. Without ergosterol, the fungus cannot survive. As a result, infection-causing fungi die.

Storage

Store in a cool and dry place away from sunlight

What if I have taken an overdose of Amortive 0.25%W/W Cream

Topical overdose with Amortive 0.25%W/W Cream is unlikely to occur. In the event of accidental ingestion, consult a doctor immediately.

Drug Warnings

Before using Amortive 0.25%W/W Cream, let your doctor know if you have a history of liver diseases, adrenal gland problems, cataracts, glaucoma, diabetes or allergic reactions to any medicine ingredient. Let your doctor know if you plan to become pregnant or already pregnant and a lactating mother. Studies show that there may be harmful effects on the baby; hence Amortive 0.25%W/W Cream should be used with caution in pregnancy under your doctor's supervision. If you apply Amortive 0.25%W/W Cream to breasts or nipple for treatment, wash it off while nursing your baby. 

Amortive 0.25%W/W Cream is for external use only, so avoid contact with the eyes, the mouth, or intravaginally. Notify the doctor if there is no improvement after one week of treatment for tinea cruris or tinea corporis or two weeks for tinea pedis. When using Amortive 0.25%W/W Cream in the groin area, patients should use the medication for two weeks only. Prolonged use of Amortive 0.25%W/W Cream may cause hormonal suppression, Cushing's syndrome, hyperglycemia (increased blood sugar level), and glucosuria (high sugar in urine) in some patients. Apply sunscreen (SPF 30 or higher) whenever you go outdoor in the sunlight.

Drug-Drug Interactions

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No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Avoid walking barefoot in places like gym showers to prevent fungal infections.
  • Do not scratch the affected area of the skin, as this can spread the infection to other parts of the body.
  • Avoid sharing towels, combs, bed sheets, shoes, or socks with others.
  • Wash your bedsheets and towels regularly.
  • Follow a candida diet if you suffer from vaginal yeast infection. Candida's diet excludes high sugary foods, some dairy products and foods with artificial preservatives.
  • Avoid or limit the intake of alcohol and caffeine.

Habit Forming

No

Therapeutic Class

ANTIFUNGALS
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Alcohol

Consult your doctor

No interactions were found. Please consult your doctor before using Amortive 0.25%W/W Cream.

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Pregnancy

Consult your doctor

Amortive 0.25%W/W Cream is a Category C pregnancy drug and is given to a pregnant woman only if the doctor thinks the benefits outweigh the risks.

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Breast Feeding

Consult your doctor

There is limited data on how Amortive 0.25%W/W Cream affects breastfeeding. Please consult your doctor before starting Amortive 0.25%W/W Cream. However, if nursing mothers apply Amortive 0.25%W/W Cream to their breasts for treatment, it is advised to wash the affected area thoroughly before breastfeeding the baby.

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Driving

Safe if prescribed

Amortive 0.25%W/W Cream does not influence on the ability to drive or use machines.

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Liver

Consult your doctor

If you have any concerns regarding the use of Amortive 0.25%W/W Cream in patients with Liver problems, please consult a doctor.

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Kidney

Safe if prescribed

Amortive 0.25%W/W Cream is safe for patients with kidney disease if prescribed by a doctor.

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Children

Consult your doctor

Amortive 0.25%W/W Cream is to be used only on children below 12 years of age when prescribed by a doctor.

Have a query?

FAQs

Amortive 0.25%W/W Cream is used to treat fungal nail infections.

Amortive 0.25%W/W Cream is safe to use with doctor's advice and over a limited period (1-2 weeks). Let your doctor know if your symptoms are not relieved by then or if you experience any side effects.

Amortive 0.25%W/W Cream consists of Amorolfine that should be used after consulting with a doctor if a person has raised blood sugar levels (diabetes mellitus).

You are required to maintain a three-hour gap after applying Amortive 0.25%W/W Cream if you are using more than one topical medication.

No, do not stop taking Amortive 0.25%W/W Cream on your own, even if the symptoms are relieved, until your course, as advised by the doctor, is finished.

There is limited data on how Amortive 0.25%W/W Cream affects breastfeeding. Please consult your doctor before starting Amortive 0.25%W/W Cream. However, if nursing mothers apply Amortive 0.25%W/W Cream to their breasts for treatment, it is advised to wash the affected area thoroughly before breastfeeding the baby.

Amortive 0.25%W/W Cream contains Amorolfine, which works by stopping the production of a chemical called ergosterol in fungi that causes nail infection. Without ergosterol, the fungus cannot survive. As a result, infection-causing fungi die.

Amortive 0.25%W/W Cream is for topical (for skin) use only. Do not put a bandage or dressing on the affected area while treating with Amortive 0.25%W/W Cream unless the doctor advises. If the medicine gets into your eyes, nose, mouth or vagina, rinse with cold water. Do not apply Amortive 0.25%W/W Cream on open wounds, lesions and blisters.

Amortive 0.25%W/W Cream, when used for longer periods, can cause thinning and weakening of the skin. Please stop using Amortive 0.25%W/W Cream and consult your doctor immediately if you experience these symptoms.

Yes, fungal infection is a contagious skin condition that spreads from one person to another through direct skin-to-skin contact, contact with contaminated soil or surfaces, or contact with infected animals. Therefore, it is recommended to avoid close direct contact until the infection is cleared and to avoid sharing items with the infected person, as this can also spread the infection.

You are recommended to apply makeup or sunscreen to the treated area of skin after a minimum of 20 minutes have passed since using Amortive 0.25%W/W Cream.

You are recommended to use Amortive 0.25%W/W Cream for as long as your doctor has prescribed it. However, if the condition worsens or persists after 2 to 4 weeks of treatment with Amortive 0.25%W/W Cream, please consult a doctor.

You should use Amortive 0.25%W/W Cream as prescribed. Your doctor will recommend the dose and duration based on the type of fungal infection. It is usually applied once a week to the affected finger or toenails. Sometimes, your doctor may ask you to use it twice a week.

No, Amortive 0.25%W/W Cream is not a steroid. Amortive 0.25%W/W Cream is an antifungal drug.

No, do not apply Amortive 0.25%W/W Cream on other parts of the body like the oral cavity, eyes or intravaginally. It should only be restricted to nails and skin. Follow your doctor’s instructions carefully.

Yes, Amortive 0.25%W/W Cream may cause allergic reactions in some people. Although, it is not very common and is likely to occur in only sensitive or susceptible people. If you experience such reactions, contact your doctor immediately.

Amortive 0.25%W/W Cream should not be used in children unless advised by a doctor.

Amortive 0.25%W/W Cream may cause skin redness as a common side effect. However, if the condition persists or worsens, consult your doctor.

Apply Amortive 0.25%W/W Cream as a thin layer evenly on the entire surface of the dry skin or nail. Always wash your hands after applying Amortive 0.25%W/W Cream. Avoid contact of Amortive 0.25%W/W Cream with the eyes, ears, and mucous membranes.

Amortive 0.25%W/W Cream may cause side effects such as itching, dry skin, redness, and a burning sensation in the skin. If these side effects persist or worsen, please consult your doctor.

Store Amortive 0.25%W/W Cream at room temperature. Protect from light. Do not freeze. Keep it out of reach of children.

If you forget to use Amortive 0.25%W/W Cream, apply it as soon as you remember. If you have concerns, discuss with your doctor.

Country of origin

India

Manufacturer/Marketer address

H.NO K-101, KH.NO,271 ABUL FAZAL ENCLAVE PART-1, OKHLA NEW DELHI South Delhi DL 110025 IN
Other Info - AMO0172

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