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compositionComposition:PROBENECID-500MG
prescription
Prescription Medicine
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Bencid Tablet is used to treat Gout and Gouty arthritis (increased uric acid leading to inflammation). It contains probenecid, which works by blocking urate tubular reabsorption and lowering serum urate levels. This prevents uric acid synthesis within the body without interfering with the necessary mechanisms of cells and the body. Common side effects of Bencid Tablet are upset stomach, headache, diarrhea, skin rash, loss of appetite, drowsiness, nausea and vomiting.

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Written By Dr. Lakshmithulasi Yarragunta , PharmD (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

PROBENECID-500MG

Manufacturer/Marketer :

Geno Pharmaceuticals Pvt Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Bencid Tablet

Bencid Tablet is a prescription medicine primarily used to treat gout and gouty arthritis by lowering high levels of uric acid in the body. It is also prescribed alongside certain antibiotic treatments to help the body keep the antibiotic in the bloodstream longer, making the infection treatment more effective.

To get the best results, you must take this medicine consistently every day exactly as your doctor directs, even if you do not have active gout symptoms. It is highly recommended to take Bencid Tablet with food or an antacid to prevent stomach upset, and you must drink plenty of water throughout the day. Making dietary changes, such as reducing purine-rich foods like red meat and seafood, can also help manage your condition.

While taking Bencid Tablet , some people may experience mild side effects like a loss of appetite, nausea, or mild headaches. However, if you experience more serious issues such as severe lower back pain, blood in your urine, or signs of a severe allergic reaction, you should seek immediate medical attention.

Do not take this medicine if you have blood disorders, uric acid kidney stones, or if you are experiencing a sudden, acute gout attack. Talk to your doctor before starting this medicine if you have kidney disease, a history of stomach ulcers, or glucose-6-phosphate dehydrogenase (G6PD) deficiency.

This medicine can interact with alcohol, which can raise uric acid levels and trigger gout attacks, as well as pain relievers like aspirin, which can make this medicine less effective. If you are pregnant, breastfeeding, or are an elderly individual, consult your doctor to discuss whether this medicine is safe for your specific needs.

Uses of Bencid Tablet

A doctor may prescribe Bencid Tablet for the following medically recognised uses:

  • Chronic Gouty Arthritis: Bencid Tablet helps prevent gout flares and reduces the buildup of painful uric acid crystals in the joints.
  • Hyperuricaemia (High Uric Acid): It lowers excess uric acid levels in the blood for people who experience frequent gout attacks.
  • Antibiotic Therapy Support: It is used alongside penicillin and related antibiotics to boost and prolong the antibiotic's levels in the blood, helping to clear infections more effectively.

Key Benefits

Bencid Tablet provides several important health benefits. These benefits include:

  • Prevention of painful gout flares: By keeping uric acid levels stable, Bencid Tablet helps you avoid the sudden, intense joint pain and swelling associated with gout attacks, allowing for easier, pain-free movement.
  • Protection against joint damage: Over time, high uric acid can cause permanent damage to your joints and tissues. This medicine helps dissolve existing crystal deposits and prevents new ones from forming, preserving your long-term joint health.
  • Enhanced antibiotic effectiveness: When taken during an infection, it helps your prescribed antibiotics work longer and more powerfully in your system, supporting a faster and more complete recovery.
Side effects of Bencid Tablet
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
  • Avoid consuming spicy, acidic, or sharp foods that can irritate gums.
  • Limit intake of citrus fruits and juices.
  • Restrict excessive alcohol consumption.
  • Opt for soft, easy-to-chew foods.
  • Use a soft-bristled toothbrush for gentle oral hygiene.
  • Floss daily to remove trapped food particles.
  • To alleviate gum soreness, try rinsing with warm salt water several times daily.
  • Apply a cold compress to reduce swelling and ease pain.
  • Consult a dentist if your gum soreness is severe, persistent, or accompanied by bleeding or swelling.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • Include iron-rich foods like dark leafy vegetables, lean red meat, legumes and fish in your diet.
  • Consume vitamin C-rich foods as they aid iron absorption.
  • Limit tea, cocoa, and coffee as these can slow iron absorption.
  • Exercise regularly; however, do not overdo it.

Directions for Use

  • It is recommended to take Bencid Tablet with food to prevent stomach upset, or as advised by the doctor.
  • Follow your doctor’s instructions on the dosage and timing of this medication to ensure safety.
  • Swallow Bencid Tablet as a whole with a glass of water.
  • Do not chew, crush, or break it.

How Bencid Tablet Works

Bencid Tablet contains probenecid, which works by acting directly on your kidneys. Your kidneys naturally filter waste from your blood, including uric acid, but they often reabsorb a large portion of it back into your bloodstream. This medicine blocks the specific proteins in the kidneys that pull uric acid back into the body. By blocking this reabsorption, Bencid Tablet forces your kidneys to pass more uric acid out through your urine. This gradually lowers the overall amount of uric acid circulating in your blood, preventing painful crystal deposits from forming in your joints. When Bencid Tablet is used with certain antibiotics, it works in a similar way by blocking the kidneys from quickly clearing the antibiotic from your body. This allows the antibiotic to stay in your bloodstream at higher, more effective levels for a longer period.
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Alcohol

Unsafe

Avoid consumption of alcohol while taking Bencid Tablet as consuming alcohol may worsen your condition.

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Pregnancy

Caution

If you are pregnant or planning pregnancy, inform your doctor before taking Bencid Tablet . Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Breast Feeding

Unsafe

It is not recommended for use in breastfeeding as it may pass into breast milk and harm your infant. Hence, if you are breastfeeding, inform your doctor before taking Bencid Tablet .

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Driving

Unsafe

Bencid Tablet may make you feel drowsy or sleepy. Do not drive or operate machinery if you are affected after taking this medicine.

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Liver

Caution

Bencid Tablet should be used with caution if you have liver problems. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Kidney

Caution

Bencid Tablet should be used with caution if you have kidney disorders. Inform your doctor if you have kidney problems like kidney stones. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Children

Unsafe

Bencid Tablet is not recommended for use in children below two years of age as the safety and efficacy are not established.

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Heart

Caution

Inform your doctor before receiving the Bencid Tablet if you have heart disease. Your doctor will prescribe only if the benefits outweigh the risks.

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Geriatrics

Consult your doctor

Limited information available about the use of Bencid Tablet in geriatric patients. Please consult your physician.

What if I have taken an overdose of Bencid Tablet

If you or someone else takes too much of this medicine, seek emergency medical attention. Symptoms of an overdose may include severe nausea, vomiting, stomach pain, or seizures.

Diet & Lifestyle Advise

  • Stay well-hydrated: Drink plenty of water (at least 2 to 3 litres daily) to help your kidneys flush out uric acid and prevent the formation of kidney stones.
  • Limit purine-rich foods: Reduce your intake of foods that increase uric acid levels, such as red meats, organ meats (like liver), shellfish, and yeast extracts.
  • Avoid alcohol and sugary drinks: Limit or avoid alcohol, especially beer, and drinks sweetened with high-fructose corn syrup, as these can trigger sudden gout attacks.
  • Maintain a healthy weight: Gradually losing excess weight can help lower uric acid levels, but avoid extreme fasting or rapid weight loss diets, as these can temporarily raise uric acid and trigger gout flares.

Health Queries

I have been suffering from chronic gout for several years and previous allopathic treatments have not provided long-term relief. What other medications or pharmaceutical options are available to effectively manage my condition?

Veda Maddala

Veda Maddala

M Pharmacy

Managing chronic, resistant gout can be challenging, but effective options remain. If standard medications like allopurinol have not worked, we can consider other pharmaceutical pathways. First, uricosuric drugs like probenecid help your kidneys excrete more uric acid. Second, for severe, hard-to-treat cases, pegloticase is an intravenous medication that actively breaks down uric acid crystals. For managing difficult flares, biologic agents targeting inflammation, such as canakinumab or anakinra, can be highly effective. Please consult your rheumatologist to discuss these advanced therapies, as they require careful monitoring but offer excellent long-term control.
health query

Have a query?

How Soon It Starts Working

The time required for Bencid Tablet to start to work: The time required for Bencid Tablet to show its action is unknown. The time for which the effects of Bencid Tablet last: The duration of action for Bencid Tablet is unknown.

What if you forget to take Bencid Tablet

Take the missed dose as soon as you remember. If it is almost time for your next scheduled dose, skip the missed dose and resume your regular schedule. Do not take a double dose to make up for a missed one.

Storage

•Store Bencid Tablet tablets at controlled room temperature, between 20°C and 25°C (68°F to 77°F).

Drug Warnings

  • Watch for early gout flares: When you first start taking Bencid Tablet , you may experience a temporary increase in gout attacks as old uric acid deposits begin to dissolve. Keep taking the medicine and talk to your doctor about temporary pain-relief options.
  • Regular kidney tests: Your doctor will likely order regular blood and urine tests to monitor your kidney function and uric acid levels while you are on this medicine.
  • Avoid aspirin: Do not take aspirin or other salicylates unless specifically directed by your doctor, as they can completely block the effects of this medicine.
  • Do not start during a flare-up: If you are having a sudden, painful gout attack, do not start taking Bencid Tablet until the acute attack has completely subsided.
  • Check for dizziness: Since this medicine can cause dizziness in some individuals, avoid driving or operating machinery until you know how it affects you.

Drug-Drug Interactions

verifiedApollotooltip
  • Salicylates (like Aspirin): Can cancel out the uric-acid-lowering effects of Bencid Tablet .
  • NSAIDs (like Indomethacin, Naproxen, or Ketoprofen): Bencid Tablet can slow down the removal of these pain relievers from your body, increasing their levels in your blood and raising the risk of side effects.
  • Methotrexate: Taking these together can cause dangerous buildups of methotrexate in your body, increasing the risk of severe toxicity.
  • Certain Antibiotics (like Penicillin or Cephalosporins): May stay in your system longer and at higher levels; while sometimes intentional, this requires close monitoring by your doctor.
ProbenecidKetorolac
Severe
ProbenecidTorasemide
Severe

Drug-Drug Interactions

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ProbenecidKetorolac
Severe
How does the drug interact with Bencid Tablet:
Coadministration of ketorolac with Bencid Tablet can increase the risk of side effects.

How to manage the interaction:
Although taking Ketorolac and Bencid Tablet together can possibly result in an interaction, but it can be taken if your doctor has prescribed it. However, if you feel lightheadedness, excessive sleepiness, reduced urination, or blood in your stools or urine more severely, consult a doctor. Do not discontinue any medications without consulting a doctor.
ProbenecidTorasemide
Severe
How does the drug interact with Bencid Tablet:
Co-administration of Bencid Tablet with torasemide can increase the risk of side effects.

How to manage the interaction:
Although taking Bencid Tablet and torasemide together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience symptoms such as blurred vision, dry mouth, dry skin, frequent urination, nausea, and stomach pain, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
  • High-purine foods, yeast supplements, or alcohol: Consuming high-purine foods, yeast supplements, or alcohol can reduce the overall clinical benefit of this medicine and trigger gout flares.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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FAQs

Bencid Tablet is used to treat Gout (increased uric acid in joints).
Bencid Tablet contains probenecid, primarily used to decrease blood uric acid levels in the body. It works by inhibiting the tubular reabsorption of urate, thus decreasing serum urate levels. It stops uric acid formation inside the body without affecting the essential mechanism of cells and the body.
The common side effects of Bencid Tablet are stomach upset, diarrhea, nausea, skin rash, drowsiness, headache, vomiting, and loss of appetite. If you experience any of these side effects or have concerns, consult your doctor.
No, Bencid Tablet should not be started during a sudden, painful gout attack, as it can actually make the flare-up worse. It is designed to prevent future attacks over the long term. If you have an active flare, talk to your doctor about fast-acting pain relief options first.
Generally, no. Aspirin and other salicylates can block Bencid Tablet from working properly to lower your uric acid. If you need a pain reliever or take low-dose aspirin for your heart, talk to your doctor before taking them together.
This medicine works by forcing your kidneys to filter more uric acid out through your urine. Drinking plenty of water (10 to 12 glasses a day) dilutes your urine and prevents this excess uric acid from forming painful kidney stones. Talk to your pharmacist if you have questions about your daily fluid intake.
It is best to avoid or strictly limit alcohol, especially beer, while taking this medicine. Alcohol increases the production of uric acid in your body and decreases your kidneys' ability to remove it, which can trigger gout attacks and reduce the effectiveness of Bencid Tablet . Talk to your doctor about safe lifestyle choices.
It is common to experience a temporary increase in gout attacks when you first start this medicine. Do not stop taking your medicine, as this is a sign that the drug is actively working to shift and clear out uric acid deposits. Talk to your doctor about safe anti-inflammatory medicines you can take to manage these early flares.
If you have moderate to severe kidney disease, Bencid Tablet may not work effectively because it relies on healthy kidneys to clear uric acid from your blood. Before starting this medicine, talk to your doctor to check if your kidney function is sufficient for this treatment.
The safety of this medicine during pregnancy or breastfeeding is not fully established. If you are pregnant, planning to become pregnant, or are nursing, talk to your doctor to weigh the potential benefits against any risks before taking this medicine.

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Reference

  1. DailyMed Database. Fdadrugxsl.Cfm Clinical Monograph. Bethesda, MD: National Library of Medicine; 2025. [Accessed on 02 Jun. 2026]Check here
  2. Drugs.com Clinical Review Team. Probenecid Pregnancy and Lactation Reference Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026]Check here
  3. Mayo Clinic Staff. Drg 20065625 Inhalation and Dosage Monograph. Rochester, MN: Mayo Foundation for Medical Education; 2025. [Accessed on 02 Jun. 2026]Check here
  4. MedlinePlus. A682395 Patient Information Monograph. Bethesda, MD: U.S. National Library of Medicine (NLM); 2025. [Accessed on 02 Jun. 2026]Check here
  5. WebMD Medical Reference Review Board. Details Drug and Treatment Monograph. Atlanta, GA: WebMD; 2026. [Accessed on 02 Jun. 2026]Check here
  6. Probenecid Probenecid. 2026. [Accessed on 15 Apr. 2026]Check here
  7. Drugs.com.Probenecid. [[Accessed on 5.Oct].2019]Check here

Country of origin

INDIA

Manufacturer/Marketer address

Geno Pharmaceuticals Pvt. Ltd., Pharmaceutical Complex, Tivim Industrial Estate, Karaswada, Mapusa, Goa - 403 526
Other Info - BEN0118

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