Combisafe-D Tablet 10's
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About Combisafe-D Tablet
Combisafe-D Tablet is used in the treatment of neuropathic pain. Neuropathic pain is a chronic progressive nerve disease that causes nerve pain due to damage to sensory nerves. Symptoms include spontaneous, untriggered pain, unpleasant feelings, shooting, burning or stabbing pain, and difficulty resting or sleeping.
Combisafe-D Tablet is a combination of alpha-lipoic acid, folic acid, methylcobalamin and pyridoxine. Methylcobalamin and pyridoxine help rejuvenate and protect damaged nerve cells. Alpha-lipoic acid provides a protective effect on nerve tissues and the brain. Folic acid helps in providing essential nutrients to the nerves. Vitamin D3 helps in the absorption of calcium.
Sometimes, you may experience common side effects such as nausea, headache, vomiting and heartburn. Most of these side effects do not require medical attention and will resolve gradually. However, talk to your doctor if you experience these side effects persistently.
Avoid taking Combisafe-D Tablet if you are allergic to any other drugs or other components present in it. Consult your doctor before using Combisafe-D Tablet if you are pregnant or breastfeeding. Combisafe-D Tablet is not recommended for children as safety and efficacy have not been established. Avoid consuming alcohol along with Combisafe-D Tablet as it could lead to unpleasant side effects.
Uses of Combisafe-D Tablet
Combisafe-D Tablet is used in the treatment of diabetic neuropathy, nutritional deficiency. The detailed uses of Combisafe-D Tablet are as follows:
- Treats Diabetic Neuropathy: Combisafe-D Tablet helps relieve nerve pain, tingling, and numbness caused by diabetes.
- Repairs Damaged Nerves: Combisafe-D Tablet aid in myelin formation, which protects nerve cells.
- Improves Nerve Function: Combisafe-D Tablet acts as an antioxidant, reducing oxidative stress and inflammation in nerve tissues.
- Corrects Vitamin Deficiencies: Combisafe-D Tablet is used especially B12, B6, D3, and folate, which are vital for red blood cell production and energy metabolism.
- Supports Bone Health: Combisafe-D Tablet enhances calcium absorption, promoting strong bones.
- Regulates Homocysteine Levels: Combisafe-D Tablet help maintain cardiovascular and cognitive health.
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Directions for Use
- Combisafe-D Tablet can be taken with or without food, as advised by your doctor.
- Follow your doctor's instructions on the dosage and timing of this medication.
- Swallow Combisafe-D Tablet as a whole with a glass of water.
- Do not crush, chew, or break it.
Medicinal Benefits
- The Combisafe-D Tablet consists of five supplements: Alpha-lipoic acid, Methylcobalamin, Cholecalciferol, Folic acid, and Pyridoxine.
- Alpha-lipoic acid is an antioxidant that helps provide a protective effect on the nerve tissues and the brain.
- Folic acid is a vitamin that helps in providing essential nutrients to nerves. It is also very useful in producing healthy red blood cells.
- Mecobalamin helps in the rejuvenation and protection of damaged nerve cells by producing a substance called myelin. It is also essential in red blood cell formation and helps in maintaining blood circulation and nerve function.
- Pyridoxine is useful in facilitating myelin and neurotransmitter synthesis. Pyridoxine also aids in the production of healthy blood cells.
- Vitamin D3, an active form of vitamin D, is essential for the absorption of calcium.
- Combisafe-D Tablet is used for the treatment of various health problems like a weak immune system, skin problems, digestive problems, defective bone growth, and neurological diseases.
How Combisafe-D Tablet Works
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What if I have taken an overdose of Combisafe-D Tablet
Drug Warnings
- Inform your doctor if you are allergic to any of the components of Combisafe-D Tablet .
- Notify your doctor if you have malabsorption syndrome (difficulty absorbing nutrition from food).
- Pregnant or breastfeeding women should consult their doctor before taking Combisafe-D Tablet .
- Excessive alcohol consumption reduces absorption and increases the elimination of folic acid. Hence, please avoid alcohol while using Combisafe-D Tablet .
- Combisafe-D Tablet is not recommended for children as safety and efficacy have not been established.
- Exercise caution while using Combisafe-D Tablet with anti-tumour drugs, antibiotics, chemotherapy, anti-diabetic drugs, thyroid hormone and blood thinners.
- Inform your doctor if you are due to undergo any surgery.
Drug-Drug Interactions
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Coadministration of Combisafe-D Tablet and Fluorouracil may increase the effects of Fluorouracil and increase the risk of serious side effects such as bleeding problems, anaemia (lack of blood), infections, and nerve damage.
How to manage the interaction:
Although there is a possible interaction between Combisafe-D Tablet and Fluorouracil, you can take these medicines together if prescribed by your doctor. However, if you experience diarrhoea, paleness of skin, severe nausea and vomiting, over-tiredness, dizziness, fainting, blood in the stools, unusual bleeding or bruising, fever, chills, body pains, flu-like symptoms, skin reactions, mouth ulcers or sores, and/or numbness, burning or tingling in your hands and feet, contact your doctor.
Co-administration of Combisafe-D Tablet with Capecitabine may increase the risk of serious side effects such as bleeding problems, anemia, infections, and nerve damage.
How to manage the interaction:
Although there is a possible interaction between Combisafe-D Tablet and Capecitabine, you can use these medicines together if prescribed by the doctor. However, if you experience paleness of skin, diarrhea, severe nausea and vomiting, over-tiredness, dizziness, fainting, blood in the stools, unusual bleeding or bruising, fever, chills, body aches, flu-like symptoms, skin reactions, mouth ulcers or sores, and/or numbness, burning or tingling sensation in the hands and feet, contact a doctor. Do not discontinue the medication without consulting a doctor. Do not discontinue the medication without consulting a doctor.
Coadministration of Combisafe-D Tablet and Cholestyramine may interfere with the absorption of Combisafe-D Tablet.
How to manage the interaction:
Although taking Cholestyramine and Combisafe-D Tablet together can result in an interaction, they can be taken together if prescribed by a doctor. However, if you experience Constipation, Diarrhea, Stomach pain, Nausea, or Loss of appetite, consult a doctor. Do not stop using any medications without consulting a doctor.
Coadministration of Combisafe-D Tablet and Carbamazepine may reduce the blood levels of Combisafe-D Tablet.
How to manage the interaction:
Although there is a possible interaction between Combisafe-D Tablet and Carbamazepine, you can take these medicines together if prescribed by your doctor. However, if your condition changes or you experience loss of seizure control, contact your doctor.
Trimethoprim may decrease the blood levels and effects of Combisafe-D Tablet.
How to manage the interaction:
Although there is a possible interaction between Combisafe-D Tablet and Trimethoprim, you can take these medicines together if prescribed by your doctor. Do not stop using any medications without consulting your doctor.
Sulfadiazine may decrease the blood levels and effects of Combisafe-D Tablet.
How to manage the interaction:
Although there is a possible interaction between Combisafe-D Tablet and Sulfadiazine, you can take these medicines together if prescribed by your doctor.
The combined use of cholecalciferol and paricalcitol are forms of vitamin D, and taking too much vitamin D may lead to toxic effects.
How to manage the interaction:
Although there is a possible interaction between Combisafe-D Tablet and paricalcitol, you can take these medicines together if prescribed by your doctor. If you notice any of these symptoms - irregular heartbeat, seizures, weakness, tiredness, headache, dizziness, ringing in the ears, loss of appetite, feeling sick, dry mouth, strange taste in your mouth, muscle or bone pain, thirst, losing weight, eye infection, sensitivity to light, runny nose or itching - contact a doctor right away. Do not discontinue any medications without consulting a doctor.
The combined use of cholecalciferol and ergocalciferol are forms of vitamin D, and taking too much vitamin D may lead to toxic effects.
How to manage the interaction:
Although there is a possible interaction between Combisafe-D Tablet and ergocalciferol, you can take these medicines together if prescribed by your doctor. If you notice any of these symptoms - irregular heartbeat, seizures, weakness, tiredness, headache, dizziness, ringing in the ears, loss of appetite, feeling sick, dry mouth, strange taste in your mouth, muscle or bone pain, thirst, losing weight, eye infection, sensitivity to light, runny nose or itching - contact a doctor right away. Do not discontinue any medications without consulting a doctor.
The combined use of aluminum hydroxide with Combisafe-D Tablet may increase the risk of toxicity.
How to manage the interaction:
Co-administration of Combisafe-D Tablet with Aluminium hydroxide can possibly result in an interaction, but it can be taken if your doctor has advised it. If you're having any of these symptoms like bone pain, muscle weakness, anemia, seizures, or dementia, it's important to contact your doctor right away. Do not stop using any medications without a doctor's advice.
The combined use of calcifediol with cholecalciferol can increase the risk of side effects.
How to manage the interaction:
Although there is a possible interaction between Combisafe-D Tablet and calcifediol, you can take these medicines together if prescribed by your doctor. If you notice any of these symptoms - irregular heartbeat, seizures, weakness, tiredness, headache, dizziness, ringing in the ears, loss of appetite, feeling sick, dry mouth, strange taste in your mouth, muscle or bone pain, thirst, losing weight, eye infection, sensitivity to light, runny nose or itching - contact a doctor right away. Do not discontinue any medications without consulting a doctor.
Drug-Food Interactions
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Diet & Lifestyle Advise
- Exercising regularly helps in improving overall health and combating pain.
- Rest well, get plenty of sleep.
- Try taking a warm bath as it can be soothing.
- Avoid smoking and alcohol consumption.
- Meditation and yoga can help lower stress, decrease pain sensitivity and improve coping skills.
- Acupuncture can be helpful by stimulating pressure points.
- Using essential oils for massages can help increase circulation.
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Alcohol
Consult your doctor
It is not known if alcohol interacts with Combisafe-D Tablet , so please consult a doctor.
Pregnancy
Consult your doctor
Please consult your doctor if you have any concerns regarding this; your doctor will advise only if the benefits outweigh the risks.
Breast Feeding
Consult your doctor
Consult your doctor before taking Combisafe-D Tablet ; your doctor will decide whether Combisafe-D Tablet can be taken by breastfeeding mothers or not.
Driving
Caution
It is unknown if Combisafe-D Tablet affects your ability to drive. Drive or operate machinery only if you are alert.
Liver
Consult your doctor
Limited information is available regarding the usage of Combisafe-D Tablet in patients with liver problems. Please consult your doctor if you have a liver impairment or any concerns regarding this.
Kidney
Consult your doctor
Limited information is available regarding the usage of Combisafe-D Tablet in patients with kidney problems. Please consult your doctor if you have kidney impairment or any concerns regarding this.
Children
Consult your doctor
Limited information is available regarding the usage of Combisafe-D Tablet in children, so please consult a doctor.
Heart
Combisafe-D Tablet is usually safe for individuals with heart problems when taken in the recommended dose. However, consult your doctor if you have any concerns or underlying heart issues.
Geriatrics
Consult your doctor
Combisafe-D Tablet should be given to elderly patients only if recommended by a doctor. If you have any concerns, please consult your doctor.
FAQs
Combisafe-D Tablet contains nutritional supplements used to treat neuropathic pain associated with diabetic neuropathy and nutritional deficiencies.
Combisafe-D Tablet is used to treat neuropathic pain associated with diabetic neuropathy. Besides this, it can also help to treat nutritional deficiency.
Combisafe-D Tablet consists of Methylcobalamin, Cholecalciferol, Alpha lipoic acid, Folic acid, and Pyridoxine. Mecobalamin and pyridoxine help in the rejuvenation and protection of damaged nerve cells by producing a substance called myelin. Alpha-lipoic acid helps in providing a protective effect on the nerve tissues and brain. Folic acid helps in providing essential nutrients to the nerves. Cholecalciferol helps in resolving neuropathic symptoms and improves balance. Together, Combisafe-D Tablet helps in providing relief from neuropathic pain.
To treat your condition effectually, continue taking Combisafe-D Tablet for as long as recommended. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Combisafe-D Tablet .
Combisafe-D Tablet may be used to treat nutritional deficiencies, helps enhance blood calcium levels, fastens metabolism, facilitates the conversion of glucose into energy, helps improve the body’s oxidative stores, and development of healthy red blood cells.
Diarrhoea could be a side-effect of Combisafe-D Tablet . Eat non-spicy meals and drink plenty of fluids if you experience diarrhoea. Consult your doctor if you have severe diarrhoea or if you find blood in stools.
Combisafe-D Tablet may be used as an adjunct therapy for diabetic patients suffering from diabetic neuropathy. However, you are advised to consult a doctor before taking Combisafe-D Tablet if you are diabetic. Combisafe-D Tablet contains alpha-lipoic acid, which might cause low blood sugar. Regularly monitor blood glucose levels while taking Combisafe-D Tablet .
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Reference
- https://www.drugs.com/mtm/alpha-lipoic-acid.html
- https://www.drugs.com/cdi/folic-acid-cyanocobalamin-and-pyridoxine.html
- https://www.drugs.com/mtm/methylcobalamin-vitamin-b12.html
- https://www.drugs.com/mtm/pyridoxine.html
- https://www.drugs.com/folic_acid.html
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6970609/
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