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Comfe XT Tablet is a nutritional supplement used to treat iron deficiency and iron-deficiency anaemia. It increases iron levels to boost red blood cell and haemoglobin production, and also replenishes folic acid to prevent folate deficiency. It supports oxygen transport, immune function, and tissue growth, and is beneficial during pregnancy and breastfeeding.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

FERROUS ASCORBATE-100MG+FOLIC ACID-1.5MG+ZINC SULPHATE-22.5MG

Manufacturer/Marketer :

Adonis Laboratories Pvt Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Comfe XT Tablet

Comfe XT Tablet is a nutritional supplement primarily used to treat and prevent iron deficiency anaemia and associated nutrient deficiencies. It helps restore depleted iron, folic acid, and zinc levels in the body to support healthy red blood cell production. This medicine is commonly prescribed when dietary intake alone is insufficient to meet your body's nutritional demands.

For the best results, you should take it consistently at the same time every day as directed by your healthcare provider. While it is ideally taken on an empty stomach for maximum absorption, you can take it with food if it causes stomach upset. Incorporating vitamin C-rich foods like citrus fruits into your diet can further improve how your body absorbs this medication.

Most people tolerate this supplement well, though some may experience mild digestive changes like temporary nausea, constipation, or dark-colored stools. These symptoms are usually harmless, but you should consult your doctor immediately if you develop severe abdominal pain, persistent vomiting, or signs of an allergic reaction.

Do not take this if you have a history of iron overload disorders like hemochromatosis or hemosiderosis. Talk to your doctor before starting if you have active stomach ulcers, inflammatory bowel disease, or chronic kidney issues, as these conditions require close monitoring during treatment.

This medicine can interact with certain antibiotics, antacids, and dairy products, which can significantly reduce its absorption. Avoid drinking alcohol or smoking while taking this supplement, as they can interfere with nutrient absorption and worsen stomach irritation. Pregnant, breastfeeding, or elderly individuals should consult their doctor to ensure the safety and appropriate dosing of this supplement.
 

Uses of Comfe XT Tablet

Your doctor may recommend this supplement to help manage the following conditions:

  • Iron Deficiency Anaemia: It helps replenish low iron levels in the body, allowing for the healthy production of haemoglobin, which carries oxygen to your organs.
  • Folic Acid Deficiency: It treats and prevents low folate levels, which are critical for building healthy red blood cells and supporting proper cellular function.
  • Zinc Deficiency: It restores zinc levels to support a healthy immune system, aid wound healing, and assist in various enzyme reactions throughout the body.
  • Nutritional Support During Pregnancy: It helps meet the increased demand for iron and folic acid during pregnancy, supporting healthy fetal development and preventing neural tube defects.
     

Key Benefits

When taken consistently as directed, this medicine may provide the following health benefits: 

  • Helps treat nutritional anaemia: This medicine helps restore essential nutrients needed to produce healthy red blood cells, reducing symptoms such as tiredness, weakness, dizziness, and low energy levels.
  • Supports recovery and overall health: It helps replenish nutrient stores after blood loss, surgery, or illness, while supporting healthy immunity, skin, and hair, contributing to overall well-being.
     

Directions for Use

  • Comfe XT Tablet may be taken with or without food, as directed by your physician.
  • It is advised to take Comfe XT Tablet once daily; however, follow your doctor's instructions regarding dosage and treatment duration.
  • Swallow Comfe XT Tablet as a whole with a glass of water.
  • Do not break, crush, or chew it.

How Comfe XT Tablet Works

Comfe XT Tablet contains Zinc sulphate, Ferrous ascorbate and Folic acid as active ingredients. It works through the combined action of three vital nutrients that target different pathways of blood cell production and cellular health. Zinc (in the form of zinc sulphate) provides elemental zinc, which acts as a crucial cofactor for more than 300 enzymes in the body. It plays a key role in synthesising proteins, supporting immune response, maintaining cell membrane integrity, and helping your body utilise iron more efficiently. Iron (in the form of ferrous ascorbate) acts as a highly absorbable source of iron. Iron is the core component of haemoglobin, the protein in red blood cells that carries oxygen from your lungs to the rest of your body. The ascorbate (Vitamin C) component keeps the iron in a soluble form, making it much easier for your intestines to absorb. Folic Acid is a type of B-vitamin that is absolutely essential for the synthesis of DNA and the proper division of cells. Without sufficient folic acid, your body cannot produce fully functional red blood cells, leading to a type of anaemia where cells are abnormally large and inefficient.
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Alcohol

Caution

Drinking alcohol may affect iron absorption; therefore, it is advised to consult your doctor before using Comfe XT Tablet .

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Pregnancy

Caution

There is limited data on how Comfe XT Tablet affects pregnancy. Please consult your doctor before starting Comfe XT Tablet if you are pregnant or planning pregnancy.

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Breast Feeding

Caution

Iron in Comfe XT Tablet can pass into breast milk when used by a breastfeeding mother. If you are a nursing mother, please consult your doctor before taking Comfe XT Tablet .

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Driving

Safe

Comfe XT Tablet usually does not interfere with your driving ability. However, please consult your doctor if you notice any side effects that affect your mental ability while using Comfe XT Tablet .

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Liver

Consult your doctor

Inform your doctor if you have any history of liver diseases before taking Comfe XT Tablet . Your doctor will weigh the benefits and potential risks before prescribing Comfe XT Tablet .

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Kidney

Consult your doctor

Inform your doctor if you have any history of kidney diseases before taking Comfe XT Tablet . Your doctor will weigh the benefits and potential risks before prescribing Comfe XT Tablet .

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Children

Caution

Comfe XT Tablet should be used in children only when recommended by a doctor. The doctor will prescribe the dosage of Comfe XT Tablet based on the child's age and weight.

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Heart

Caution

Comfe XT Tablet should be used with caution and under medical supervision in patients with heart problems. Therefore, please consult your doctor before using Comfe XT Tablet .

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Geriatrics

Consult your doctor

Please consult a doctor before administering Comfe XT Tablet to geriatric patients. Your doctor will prescribe Comfe XT Tablet if the benefits outweigh the risks.

What if I have taken an overdose of Comfe XT Tablet

In case of an accidental overdose, seek immediate medical attention. Iron overdose can be serious, especially in children, and may present with severe vomiting, stomach pain, or extreme drowsiness.

Diet & Lifestyle Advise

  • Avoid tea, coffee, and milk: Do not drink tea, coffee, or milk within 2 hours of taking this medicine, as they can reduce iron absorption.
  • Include vitamin C-rich foods: Eat foods such as oranges, lemons, strawberries, or bell peppers to help your body absorb iron more effectively.
  • Stay hydrated: Drink plenty of water and eat fibre-rich foods to help prevent constipation, a common side effect of iron supplements.
  • Separate calcium and antacids: Take calcium supplements or antacids at least 2 hours before or after this medicine to avoid reducing iron absorption.
     
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How Soon It Starts Working

  • The time required for Comfe XT Tablet to start to work: Comfe XT Tablet ideally shows its action within a few hours after administration.
  • The time for which the effects of Comfe XT Tablet last: The duration of action for Comfe XT Tablet is unknown.

Storage

•Store it at room temperature, ideally between 15°C and 30°C, in a cool, dry place.

What if you forget to take Comfe XT Tablet

If you miss a dose of the supplement, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed one and continue with your regular schedule. Do not take a double dose to make up for a missed one.

Drug Warnings

  • Do not be alarmed by dark stools: Iron in this medicine may cause your stools to appear dark or black. This is a common and harmless side effect.
  • Check the expiry date: Do not take the medicine if it has expired.
  • Inform your healthcare provider: Tell your doctor or laboratory staff that you are taking this medicine before stool tests, as iron may affect some test results.
  • Avoid extra iron or zinc supplements: Do not take other iron-, zinc-, or mineral-containing supplements unless advised by your doctor or pharmacist, as this may increase the risk of side effects or overdose.
     

Drug-Drug Interactions

verifiedApollotooltip
  • Antacids and Proton Pump Inhibitors: May lower stomach acid, reducing the absorption of iron.
  • Antibiotics (such as tetracyclines and fluoroquinolones): They can bind to these drugs, reducing the effectiveness of both the antibiotic and the supplement. Space them at least 2 hours apart.
  • Thyroid Medications (such as levothyroxine): Iron can decrease the absorption of thyroid hormones. Take these medications at least 4 hours apart.

 

Ferrous ascorbate + Folic acid + Zinc sulfateDolutegravir
Severe
Ferrous ascorbate + Folic acid + Zinc sulfateDimercaprol
Severe

Drug-Drug Interactions

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Ferrous ascorbate + Folic acid + Zinc sulfateDolutegravir
Severe
How does the drug interact with Comfe XT Tablet:
Co-administration of dolutegravir with Comfe XT Tablet can reduce the effects of dolutegravir.

How to manage the interaction:
Although taking Dolutegravir and Comfe XT Tablet together can possibly result in an interaction, they can be taken together if prescribed by a doctor. In case you experience any unusual side effects, consult a doctor. Do not discontinue using any medications without consulting a doctor.
Ferrous ascorbate + Folic acid + Zinc sulfateDimercaprol
Severe
How does the drug interact with Comfe XT Tablet:
Co-administration of Comfe XT Tablet with Dimercaprol can lead to kidney and ear problems.

How to manage the interaction:
.
Ferrous ascorbate + Folic acid + Zinc sulfateFluorouracil
Severe
How does the drug interact with Comfe XT Tablet:
Co-administration of Comfe XT Tablet with Fluorouracil may increase the side effects of Fluorouracil.

How to manage the interaction:
Although there is a possible interaction between Comfe XT Tablet and Fluorouracil, you can take these medicines together if prescribed by a doctor. If you experience any unusual symptoms like Severe nausea and vomiting, loose stools, paleness of skin, tiredness, confusion, fainting, unusual bleeding or bruising, blood in the stools, fever, chills, body pains, mouth ulcers or sores, or numbness or tingling sensation in hands or feet, consult a doctor. Do not discontinue any medications without consulting a doctor.
Ferrous ascorbate + Folic acid + Zinc sulfateCapecitabine
Severe
How does the drug interact with Comfe XT Tablet:
Co-administration of Comfe XT Tablet with Capecitabine may increase the risk of side effects.

How to manage the interaction:
Although there is a possible interaction between Comfe XT Tablet and Capecitabine, you can use them together if prescribed by a doctor. However, if you experience any symptoms like pale skin, loose stools, nausea and vomiting, tiredness, dizziness, fainting, blood in the stools, unusual bleeding or bruising, fever, chills, body aches, itchy skin, mouth ulcers , or numbness or burning sensation in the hands and feet, contact a doctor. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
  • Dairy Products: High calcium foods can significantly lower the absorption of iron and zinc.
  • Tea and Coffee: These contain compounds that bind to iron, preventing it from being absorbed by your gut.
     
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[NUTRITIONAL SUPPLEMENT]

FAQs

Comfe XT Tablet is a nutritional supplement used to treat iron deficiency and its associated anaemia.
Comfe XT Tablet contains Zinc Sulphate, Ferrous Ascorbate, and Folic acid. It works by restoring iron levels and boosting the body’s production of red blood cells and haemoglobin, thereby treating and preventing iron-deficiency anaemia.
It is recommended not to take Comfe XT Tablet along with tea, coffee, milk, and eggs since they might interfere with iron absorption from Comfe XT Tablet .
Comfe XT Tablet is best absorbed if taken on an empty stomach. However, in some patients, Comfe XT Tablet may cause gastrointestinal disturbances, such as stomach upset or constipation, when taken without food. Please take it as recommended by your physician if you have stomach problems.
Antacids may interfere with the absorption of iron. Hence, taking Comfe XT Tablet two hours before or four hours after taking antacids is advised.
Zinc Sulphate may reduce antibiotic absorption, thereby reducing their effectiveness. Maintaining at least a 1-hour interval between Comfe XT Tablet and other antibiotics is recommended.
Before taking Comfe XT Tablet , inform your doctor about all your medical conditions and medicines, especially if you have kidney or liver disease, bleeding disorders, allergies, are pregnant or breastfeeding, or have conditions like hemochromatosis or zinc toxicity, to ensure safe use and avoid potential interactions.
Comfe XT Tablet is not generally known to cause sleepiness. However, some individuals may experience sleepiness as a side effect. If you feel unusually sleepy after taking this supplement, consult your doctor to rule out any underlying causes or potential interactions with other medications.
The side effects of Comfe XT Tablet include nausea, constipation, diarrhoea, and stomach upset. These side effects do not require medical attention and gradually resolve over time. However, please consult a doctor if they persist longer.
The dark or black colour in your stool is completely harmless. It happens because your body does not absorb all the iron in the tablet, and the unabsorbed iron passes out in your stool, changing its colour. If you experience severe abdominal pain or notice blood in your stool, talk to your doctor.
Yes, this combination is commonly prescribed during pregnancy to support the increased nutritional needs of both mother and baby. However, you should only take it under the guidance of your healthcare provider to ensure the dosage is safe for your stage of pregnancy. Talk to your doctor.
Mild constipation is a common side effect of iron supplements. You can manage this by drinking plenty of water, eating fibre-rich foods, and staying physically active. If the constipation is severe or persistent, do not take laxatives without guidance; instead, talk to your doctor.
If you have active stomach ulcers or severe gastrointestinal inflammation, oral iron supplements can cause further irritation to your stomach lining. Your doctor will evaluate if this medication is suitable for you or if an alternative is needed. Talk to your doctor.
You can take it at any time of day, as long as you take it consistently at the same time. Many people find it easiest to take it in the morning on an empty stomach for optimal absorption. If it causes morning nausea, you can discuss timing options with your healthcare provider. Talk to your doctor.
No, you should not take them at the same time because the iron in the supplement can significantly reduce the absorption of thyroid medications like levothyroxine, making your thyroid treatment less effective. You should separate these two medications by at least four hours. Talk to your doctor.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

C-6, Groma House, Apmc Market ,Sector 19, Vashi, Navi Mumbai €“ 400 703
Other Info - COM0313

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