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compositionComposition:TRIOXSALEN-0.2%W/V
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Dsorolen Lotion is a medication primarily used to treat vitiligo (a condition in which the skin loses its pigment cells (melanocytes)) and psoriasis (a skin disease that causes red, itchy, scaly patches). It improves the appearance of afflicted skin, lessens inflammation and scaling, and helps restore skin colour.

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Written By Lakshmithulasi Yarragunta , PharmD (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

TRIOXSALEN-0.2%W/V

Manufacturer/Marketer :

Dwd Pharmaceuticals Ltd

Consume Type :

Topical

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Dsorolen Lotion

Dsorolen Lotion is a topical skin treatment used in combination with controlled ultraviolet light therapy to help restore skin color. It is primarily prescribed for skin conditions like vitiligo, where patches of skin lose their natural pigment, and sometimes psoriasis. Dsorolen Lotion works by making your skin more sensitive to light, which helps stimulate the cells that produce your natural skin color.

For the best results, you must apply Dsorolen Lotion consistently and exactly at the scheduled times before your light therapy sessions. Consistency is highly important, as skipping applications can delay the restoration of your skin's pigment. While using this treatment, making certain diet and lifestyle changes—such as avoiding natural sun exposure and eating antioxidant-rich foods—can support your skin's healing process.

While Dsorolen Lotion is highly effective, it can cause mild side effects like skin redness, itching, or dryness. If you experience severe burning, blistering, or skin pain, you must stop using the product immediately and consult your doctor or pharmacist. Always talk to your doctor or pharmacist if you notice any unusual changes in your skin.

Talk to your doctor before starting Dsorolen Lotion if you have any pre-existing health conditions, especially those related to light sensitivity. Do not use this if you have autoimmune conditions like lupus, porphyria, or a history of skin cancer, as these make your skin highly vulnerable to light damage.

Let your doctor know about any other medicines you are taking, as some can increase your risk of severe sunburns. If you are pregnant, breastfeeding, or elderly, talk to your doctor or pharmacist before starting treatment to ensure it is safe for your specific situation.

Uses of Dsorolen Lotion

Dsorolen Lotion is used in the treatment of vitiligo and psoriasis. The detailed uses of Dsorolen Lotion are as follows:

  • Vitiligo: Dsorolen Lotion helps by making the affected skin patches more sensitive to medical ultraviolet light, which encourages the pigment-producing cells to bring back natural skin color.
  • Psoriasis: When used alongside light therapy, Dsorolen Lotion helps slow down the overactive growth of skin cells, which reduces the formation of scaly patches and plaques on the skin.

Key Benefits

Dsorolen Lotion helps manage certain skin conditions by improving the skin's response to ultraviolet (UV) light therapy. It supports the restoration of normal skin appearance and helps improve overall skin health. Benefits may include:

  • Helps restore skin pigmentation in people with vitiligo when used with UV light therapy.
  • Supports repigmentation of affected skin areas.
  • Helps manage symptoms of psoriasis, including thick, scaly skin patches.
  • Reduces skin irritation and improves overall skin comfort.
  • Promotes healthier skin appearance and improved skin tone.
  • Supports long-term management of chronic skin conditions under medical supervision.

Directions for Use

  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Check the label for directions before using this medicine. Apply the prescribed amount of Dsorolen Lotion as a thin layer to the clean and dry affected area.
  • Wash your hands before and after using Dsorolen Lotion.
  • If Dsorolen Lotion accidentally comes into contact with the nose, mouth, or eyes, rinse with water thoroughly.

How Dsorolen Lotion Works

Dsorolen Lotion contains Trioxsalen, which belongs to a group of medicines called photosensitizers. It is applied directly to the skin, where it is absorbed by the outer layers of skin cells. On its own, the medicine remains inactive and does not affect the skin. However, when the treated skin is exposed to specific ultraviolet A (UVA) light, Dsorolen Lotion becomes active. It binds to the DNA inside the target skin cells. In vitiligo, this activation stimulates the pigment-producing cells (melanocytes) to produce melanin, which darkens the skin. In psoriasis, this process slows down the rapid and abnormal multiplication of skin cells, helping the skin return to a healthier state.
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Alcohol

Consult your doctor

It is not known whether Dsorolen Lotion will interact with alcohol. Consult your doctor in case of concerns.

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Pregnancy

Consult your doctor

Dsorolen Lotion belongs to FDA Category C (Animal reproduction studies have shown an adverse effect on the fetus in pregnancy). Although it is a topical preparation, it should be used by discussing the risks and benefits of this medicine with your doctor.

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Breast Feeding

Consult your doctor

Dsorolen Lotion should be used with caution while breastfeeding. Although it is a topical preparation, it should be used by discussing the risks and benefits of this medicine with your physician.

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Driving

Safe if prescribed

Dsorolen Lotion does not affect your ability to drive.

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Liver

Caution

Dsorolen Lotion should be used with caution in patients with liver disease. Hence, use it as advised by your physician.

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Kidney

Caution

Dsorolen Lotion should be used with caution in patients with kidney disease. Hence, use it as advised by your physician.

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Children

Consult your doctor

Dsorolen Lotion should be used in children below 12 years of age only if prescribed by your paediatrician.

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Heart

Consult your doctor

Please inform your doctor if you have a history of heart disease before using Dsorolen Lotion. Your doctor will prescribe it only if the benefits outweigh the risks.

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Geriatrics

Consult your doctor

Limited information available for use of Dsorolen Lotion in elderly patients. Please consult your doctor.

What if I have taken an overdose of Dsorolen Lotion

If you apply too much of Dsorolen Lotion, or if it is accidentally swallowed, seek immediate medical attention or contact a poison control center. Overuse followed by light exposure can lead to severe, painful skin burns and blistering.

Diet & Lifestyle Advise

  • Avoid sunlight exposure: Stay out of direct sunlight and do not use tanning beds for at least 24 to 48 hours after applying Dsorolen Lotion, as your skin will remain highly sensitive to burns.
  • Wear protective clothing: When outdoors, wear tightly woven clothing that covers your arms and legs, a wide-brimmed hat, and UV-blocking sunglasses to protect your skin and eyes.
  • Limit certain foods: Avoid eating large amounts of foods that naturally increase light sensitivity, such as celery, carrots, figs, limes, parsley, and mustard, while undergoing treatment.
  • Keep skin moisturized: Apply a gentle, fragrance-free moisturizer between treatments to help soothe dry or peeling skin, but do not apply it right before your Dsorolen Lotion application.

Health Queries

I have white patches on my skin that may be leucoderma (vitiligo). What are the possible treatments and can it be cured?

G.santoshini Reddy

G.santoshini Reddy

M Pharmacy (Pharmaceutics)

White patches on the skin can be due to Vitiligo, where the cells that give colour to the skin stop working, leading to pale or white areas. It is not an infection, not contagious, and does not spread by touch. The condition can be slow or sometimes spread over time, but in many people, it can be controlled and improved with treatment. Doctors may recommend medicated creams (such as mild steroid or other prescription creams) to help restore some colour, and in certain cases, light-based therapy can be used to stimulate repigmentation. Protecting the skin from sunburn by using sunscreen is important, as white patches are more sensitive. While there is no guaranteed permanent cure in every case, many people see good improvement and regain colour in patches with proper treatment and follow-up. Early consultation with a dermatologist gives better results and helps plan the right treatment for your skin.

My vitiligo has been increasing quickly since the last time, and I'm not sure what to do at the moment. I have been taking 25 mg of Dsorolen twice a week, separated by two days, for the past 26 days. I also use Cosvaate-GM at night.

Y. Lakshmi Thulasi

Y. Lakshmi Thulasi

Pharm-D (Post baccalaureate)

If Vitiligo is spreading quickly despite treatment with Dsorolen and Cosvate GM, it suggests the disease is currently active and may need adjustment in therapy. Do not increase or continue these medicines on your own, as they require careful monitoring; a dermatologist may consider options like phototherapy, stronger immunomodulators, or reviewing your current regimen. Avoid skin injury, manage stress, and consult a dermatologist soon for proper evaluation and updated treatment.
health query

Have a query?

How Soon It Starts Working

  • The time required for Dsorolen Lotion to start to work: The time required for this medicine to show its action is about 6 months of consistent use for vitiligo and about 1 hour for increasing the sensitivity of the skin to sunlight.
  • The time for which the effects of Dsorolen Lotion last: The effect of Dsorolen Lotion lasts for 8 hours.

Storage

• Store in a cool and dry place away from sunlight.• Keep Dsorolen Lotion out of the sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if you forget to take Dsorolen Lotion

If you miss a dose of Dsorolen Lotion before your scheduled light therapy session, do not apply a double amount to catch up. Contact your light therapy center or doctor immediately for instructions on whether to reschedule your treatment session.

Drug Warnings

  • Inspect the medicine before use: Do not use the liquid or cream if it has changed colour, appears cloudy, or contains unusual particles.
  • Avoid applying to damaged skin: Do not use Dsorolen Lotion on sunburned, raw, or irritated skin unless specifically instructed by your doctor.
  • Protect your eyes during light therapy: Always wear UV-blocking protective goggles during light treatment to help prevent serious eye damage, including cataracts.
  • Apply only to the affected areas: Do not apply Dsorolen Lotion to skin that is not being treated, as it may increase the risk of severe burns during light therapy.
  • Follow the prescribed light exposure schedule: Carefully follow your doctor's instructions for light therapy duration. Even a small increase in exposure time may cause severe skin burns or damage.

Drug-Drug Interactions

verifiedApollotooltip
  • Thiazide diuretics (water pills): Taking these medicines alongside Dsorolen Lotion may increase your skin's sensitivity to sunlight and raise the risk of severe sunburn and skin damage.
  • Tetracycline antibiotics: Combining these with Dsorolen Lotion may increase the risk of severe sunburn and other light-related skin reactions.
  • Sulfa medicines: Taking these alongside Dsorolen Lotion may make your skin more sensitive to sunlight, increasing the risk of burns and skin irritation.
  • Coal tar products: Using these together with Dsorolen Lotion may further increase your skin's sensitivity to ultraviolet (UV) light and raise the risk of skin damage.
No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

verifiedApollotooltip
  • Limes, figs, celery, and parsley: Consuming large amounts of these foods may make your skin more sensitive to light and increase the risk of burns during treatment with Dsorolen Lotion.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[PHOTOSENSITIZER]

FAQs

Dsorolen Lotion is used in the treatment of psoriasis and vitiligo.
Dsorolen Lotion works by reducing the overproduction of skin cells. In vitiligo, it activates certain skin cells (melanocytes) and helps re-pigment the discoloured, white patches.
Dsorolen Lotion should be used with caution in patients who are allergic to sunlight, porphyria, heart disease, liver diseases, stomach problems, cataracts, skin cancers and lupus erythematosus condition.
Yes, Dsorolen Lotion may cause vision problems. To overcome vision problems, periodically consult your eye physician.
No. You must avoid direct sunlight and UV exposure after applying Dsorolen Lotion, as it makes your skin extremely sensitive to burning. If you must go outdoors, protect your skin completely with clothing and sunscreen. Talk to your doctor for specific instructions
Skin pigment restoration is a gradual process. It can take several weeks or months of consistent treatment combined with light therapy to see noticeable changes in skin colour. Talk to your doctor if you have concerns about your progress.
Yes. Your eyes can also become sensitive to light after using Dsorolen Lotion. It is highly recommended to wear wrap-around, UV-blocking sunglasses for 24 hours after application when you are outdoors or near bright windows. Talk to your doctor for guidance.
The safety of using Dsorolen Lotion during pregnancy is not fully established. You should discuss the risks and benefits thoroughly with your healthcare provider. Talk to your doctor if you are pregnant or planning to become pregnant.
Do not apply cosmetics, lotions, or other skin products over the treated area before your light therapy session, as they can block the light or react with the medicine. You may apply them after your treatment is finished and the skin is washed. Talk to your doctor for advice.
If you have already applied Dsorolen Lotion but cannot attend your light therapy session, wash the medicine off your skin immediately. Avoid light exposure for 24 to 48 hours and contact your clinic right away. Talk to your doctor for further instructions.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. PubChem PubChem. [Accessed on 03 Apr. 2019]Check here
  2. O P Salo, A Lassus, J Taskinen. NIH National Library of Medicine, National center .or biotechnology information. Trioxsalen bath plus UVA treatment of psoriasis. Plasma concentration of the drug and clinical results. 1981. [Accessed on 22nd July 2022]Check here
  3. M Hannuksela, J Karvonen. NIH National Library of Medicine, National center for biotechnology information. Trioxsalen bath plus UVA effective and safe in the treatment of psoriasis. [Revised on December 1978] [Accessed on 22nd July 2022]Check here
  4. Drugbank. Trioxsalen. [Revised on September 2007] [Accessed on 22nd July 2022]Check here
  5. Photochemotherapy (PUVA) in psoriasis and vitiligo. [Accessed on 02 Jun. 2026]Check here
  6. DWD Pharmaceuticals Ltd. Med India, Trioxsalen. [Accessed on 22nd July 2022]Check here

Country of origin

INDIA

Manufacturer/Marketer address

Claris Corporate Headquarters, Nr. Parimal Crossing, Ellisbridge, Ahmedabad - 380 006, India.
Other Info - DSO0002
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