apollo
logo
0

Welcome User

Login/Sign Up

Home
Buy Medicines
Lab Tests
Doctor Consult
Circle Membership
insurance
Blogs
Contact Us
Privacy Policy
Return & Refunds
Need Help
Terms and Conditions
Select Delivery Location
compositionComposition:TRIOXSALEN-0.2%W/V
image icons
image icons
image icons
image icons
image icons
image icons
Best Price

₹121 with coupons & bank offers*

View

Pigolyn Lotion is a medication primarily used to treat vitiligo (a condition in which the skin loses its pigment cells (melanocytes)) and psoriasis (a skin disease that causes red, itchy, scaly patches). It improves the appearance of afflicted skin, lessens inflammation and scaling, and helps restore skin colour.

Read more
Written By Lakshmithulasi Yarragunta , PharmD (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
OffersOffers & Discounts

Get Free delivery (₹99) with circle icon

Join Circle
Get Extra 18% Off with Coupons
Extra 10% Off with Bank Offers
bank offer
bank offer
bank offer

More about the Product

Composition :

TRIOXSALEN-0.2%W/V

Manufacturer/Marketer :

Praise Pharma

Consume Type :

Topical

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Pigolyn Lotion

Pigolyn Lotion is a topical skin treatment used in combination with controlled ultraviolet light therapy to help restore skin color. It is primarily prescribed for skin conditions like vitiligo, where patches of skin lose their natural pigment, and sometimes psoriasis. Pigolyn Lotion works by making your skin more sensitive to light, which helps stimulate the cells that produce your natural skin color.

For the best results, you must apply Pigolyn Lotion consistently and exactly at the scheduled times before your light therapy sessions. Consistency is highly important, as skipping applications can delay the restoration of your skin's pigment. While using this treatment, making certain diet and lifestyle changes—such as avoiding natural sun exposure and eating antioxidant-rich foods—can support your skin's healing process.

While Pigolyn Lotion is highly effective, it can cause mild side effects like skin redness, itching, or dryness. If you experience severe burning, blistering, or skin pain, you must stop using the product immediately and consult your doctor or pharmacist. Always talk to your doctor or pharmacist if you notice any unusual changes in your skin.

Talk to your doctor before starting Pigolyn Lotion if you have any pre-existing health conditions, especially those related to light sensitivity. Do not use this if you have autoimmune conditions like lupus, porphyria, or a history of skin cancer, as these make your skin highly vulnerable to light damage.

Let your doctor know about any other medicines you are taking, as some can increase your risk of severe sunburns. If you are pregnant, breastfeeding, or elderly, talk to your doctor or pharmacist before starting treatment to ensure it is safe for your specific situation.

Uses of Pigolyn Lotion

Pigolyn Lotion is used in the treatment of vitiligo and psoriasis. The detailed uses of Pigolyn Lotion are as follows:

  • Vitiligo: Pigolyn Lotion helps by making the affected skin patches more sensitive to medical ultraviolet light, which encourages the pigment-producing cells to bring back natural skin color.
  • Psoriasis: When used alongside light therapy, Pigolyn Lotion helps slow down the overactive growth of skin cells, which reduces the formation of scaly patches and plaques on the skin.

Key Benefits

Pigolyn Lotion helps manage certain skin conditions by improving the skin's response to ultraviolet (UV) light therapy. It supports the restoration of normal skin appearance and helps improve overall skin health. Benefits may include:

  • Helps restore skin pigmentation in people with vitiligo when used with UV light therapy.
  • Supports repigmentation of affected skin areas.
  • Helps manage symptoms of psoriasis, including thick, scaly skin patches.
  • Reduces skin irritation and improves overall skin comfort.
  • Promotes healthier skin appearance and improved skin tone.
  • Supports long-term management of chronic skin conditions under medical supervision.

Directions for Use

  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Check the label for directions before using this medicine. Apply the prescribed amount of Pigolyn Lotion as a thin layer to the clean and dry affected area.
  • Wash your hands before and after using Pigolyn Lotion.
  • If Pigolyn Lotion accidentally comes into contact with the nose, mouth, or eyes, rinse with water thoroughly.

How Pigolyn Lotion Works

Pigolyn Lotion contains Trioxsalen, which belongs to a group of medicines called photosensitizers. It is applied directly to the skin, where it is absorbed by the outer layers of skin cells. On its own, the medicine remains inactive and does not affect the skin. However, when the treated skin is exposed to specific ultraviolet A (UVA) light, Pigolyn Lotion becomes active. It binds to the DNA inside the target skin cells. In vitiligo, this activation stimulates the pigment-producing cells (melanocytes) to produce melanin, which darkens the skin. In psoriasis, this process slows down the rapid and abnormal multiplication of skin cells, helping the skin return to a healthier state.
bannner image

Alcohol

Consult your doctor

It is not known whether Pigolyn Lotion will interact with alcohol. Consult your doctor in case of concerns.

bannner image

Pregnancy

Consult your doctor

Pigolyn Lotion belongs to FDA Category C (Animal reproduction studies have shown an adverse effect on the fetus in pregnancy). Although it is a topical preparation, it should be used by discussing the risks and benefits of this medicine with your doctor.

bannner image

Breast Feeding

Consult your doctor

Pigolyn Lotion should be used with caution while breastfeeding. Although it is a topical preparation, it should be used by discussing the risks and benefits of this medicine with your physician.

bannner image

Driving

Safe if prescribed

Pigolyn Lotion does not affect your ability to drive.

bannner image

Liver

Caution

Pigolyn Lotion should be used with caution in patients with liver disease. Hence, use it as advised by your physician.

bannner image

Kidney

Caution

Pigolyn Lotion should be used with caution in patients with kidney disease. Hence, use it as advised by your physician.

bannner image

Children

Consult your doctor

Pigolyn Lotion should be used in children below 12 years of age only if prescribed by your paediatrician.

bannner image

Heart

Consult your doctor

Please inform your doctor if you have a history of heart disease before using Pigolyn Lotion. Your doctor will prescribe it only if the benefits outweigh the risks.

bannner image

Geriatrics

Consult your doctor

Limited information available for use of Pigolyn Lotion in elderly patients. Please consult your doctor.

What if I have taken an overdose of Pigolyn Lotion

If you apply too much of Pigolyn Lotion, or if it is accidentally swallowed, seek immediate medical attention or contact a poison control center. Overuse followed by light exposure can lead to severe, painful skin burns and blistering.

Diet & Lifestyle Advise

  • Avoid sunlight exposure: Stay out of direct sunlight and do not use tanning beds for at least 24 to 48 hours after applying Pigolyn Lotion, as your skin will remain highly sensitive to burns.
  • Wear protective clothing: When outdoors, wear tightly woven clothing that covers your arms and legs, a wide-brimmed hat, and UV-blocking sunglasses to protect your skin and eyes.
  • Limit certain foods: Avoid eating large amounts of foods that naturally increase light sensitivity, such as celery, carrots, figs, limes, parsley, and mustard, while undergoing treatment.
  • Keep skin moisturized: Apply a gentle, fragrance-free moisturizer between treatments to help soothe dry or peeling skin, but do not apply it right before your Pigolyn Lotion application.
health query

Have a query?

How Soon It Starts Working

  • The time required for Pigolyn Lotion to start to work: The time required for this medicine to show its action is about 6 months of consistent use for vitiligo and about 1 hour for increasing the sensitivity of the skin to sunlight.
  • The time for which the effects of Pigolyn Lotion last: The effect of Pigolyn Lotion lasts for 8 hours.

Storage

• Store in a cool and dry place away from sunlight.• Keep Pigolyn Lotion out of the sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if you forget to take Pigolyn Lotion

If you miss a dose of Pigolyn Lotion before your scheduled light therapy session, do not apply a double amount to catch up. Contact your light therapy center or doctor immediately for instructions on whether to reschedule your treatment session.

Drug Warnings

  • Inspect the medicine before use: Do not use the liquid or cream if it has changed colour, appears cloudy, or contains unusual particles.
  • Avoid applying to damaged skin: Do not use Pigolyn Lotion on sunburned, raw, or irritated skin unless specifically instructed by your doctor.
  • Protect your eyes during light therapy: Always wear UV-blocking protective goggles during light treatment to help prevent serious eye damage, including cataracts.
  • Apply only to the affected areas: Do not apply Pigolyn Lotion to skin that is not being treated, as it may increase the risk of severe burns during light therapy.
  • Follow the prescribed light exposure schedule: Carefully follow your doctor's instructions for light therapy duration. Even a small increase in exposure time may cause severe skin burns or damage.

Drug-Drug Interactions

verifiedApollotooltip
  • Thiazide diuretics (water pills): Taking these medicines alongside Pigolyn Lotion may increase your skin's sensitivity to sunlight and raise the risk of severe sunburn and skin damage.
  • Tetracycline antibiotics: Combining these with Pigolyn Lotion may increase the risk of severe sunburn and other light-related skin reactions.
  • Sulfa medicines: Taking these alongside Pigolyn Lotion may make your skin more sensitive to sunlight, increasing the risk of burns and skin irritation.
  • Coal tar products: Using these together with Pigolyn Lotion may further increase your skin's sensitivity to ultraviolet (UV) light and raise the risk of skin damage.
No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

Login/Sign Up

Drug-Food Interactions

verifiedApollotooltip
  • Limes, figs, celery, and parsley: Consuming large amounts of these foods may make your skin more sensitive to light and increase the risk of burns during treatment with Pigolyn Lotion.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

Login/Sign Up

All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[PHOTOSENSITIZER]

FAQs

Pigolyn Lotion is used in the treatment of psoriasis and vitiligo.
Pigolyn Lotion works by reducing the overproduction of skin cells. In vitiligo, it activates certain skin cells (melanocytes) and helps re-pigment the discoloured, white patches.
Pigolyn Lotion should be used with caution in patients who are allergic to sunlight, porphyria, heart disease, liver diseases, stomach problems, cataracts, skin cancers and lupus erythematosus condition.
Yes, Pigolyn Lotion may cause vision problems. To overcome vision problems, periodically consult your eye physician.
No. You must avoid direct sunlight and UV exposure after applying Pigolyn Lotion, as it makes your skin extremely sensitive to burning. If you must go outdoors, protect your skin completely with clothing and sunscreen. Talk to your doctor for specific instructions
Skin pigment restoration is a gradual process. It can take several weeks or months of consistent treatment combined with light therapy to see noticeable changes in skin colour. Talk to your doctor if you have concerns about your progress.
Yes. Your eyes can also become sensitive to light after using Pigolyn Lotion. It is highly recommended to wear wrap-around, UV-blocking sunglasses for 24 hours after application when you are outdoors or near bright windows. Talk to your doctor for guidance.
The safety of using Pigolyn Lotion during pregnancy is not fully established. You should discuss the risks and benefits thoroughly with your healthcare provider. Talk to your doctor if you are pregnant or planning to become pregnant.
Do not apply cosmetics, lotions, or other skin products over the treated area before your light therapy session, as they can block the light or react with the medicine. You may apply them after your treatment is finished and the skin is washed. Talk to your doctor for advice.
If you have already applied Pigolyn Lotion but cannot attend your light therapy session, wash the medicine off your skin immediately. Avoid light exposure for 24 to 48 hours and contact your clinic right away. Talk to your doctor for further instructions.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. PubChem PubChem. [Accessed on 03 Apr. 2019]Check here
  2. O P Salo, A Lassus, J Taskinen. NIH National Library of Medicine, National center .or biotechnology information. Trioxsalen bath plus UVA treatment of psoriasis. Plasma concentration of the drug and clinical results. 1981. [Accessed on 22nd July 2022]Check here
  3. M Hannuksela, J Karvonen. NIH National Library of Medicine, National center for biotechnology information. Trioxsalen bath plus UVA effective and safe in the treatment of psoriasis. [Revised on December 1978] [Accessed on 22nd July 2022]Check here
  4. Drugbank. Trioxsalen. [Revised on September 2007] [Accessed on 22nd July 2022]Check here
  5. Photochemotherapy (PUVA) in psoriasis and vitiligo. [Accessed on 02 Jun. 2026]Check here
  6. DWD Pharmaceuticals Ltd. Med India, Trioxsalen. [Accessed on 22nd July 2022]Check here

Country of origin

India

Manufacturer/Marketer address

Block No:1, Paul Warehouse,S.No:222/6, Dhangar Wasti, Mahatma Phule Nagar, Uruli Devachi, Tal.Haveli, Dist. Pune, Maharashtra, India. 412308
Other Info - PIG0439

Buy best Dermatology products by

whatsapp Floating Button
Buy Now
Add to Cart