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compositionComposition:FLUOROURACIL-1%W/W
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Prescription Medicine
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Fluo 1% Cream is used to treat skin conditions such as keratosis (skin growths), some simple skin cancers, keratoacanthoma (a firm nodule on the skin), and Bowen’s disease. It may also be helpful in the treatment of superficial basal cell carcinoma. It contains Fluorouracil, which destroys cancerous and pre-cancerous cells while having little effect on normal cells. Common side effects of Fluo 1% Cream are nausea, dizziness, headache, and taste disturbance.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

FLUOROURACIL-1%W/W

Manufacturer/Marketer :

West Coast Pharmaceuticals Pvt Ltd

Consume Type :

Topical

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Fluo 1% Cream

About Fluo 1% Cream
Fluo 1% Cream is a prescription topical medication used to treat pre-cancerous skin patches known as actinic keratoses. It is also prescribed for certain types of superficial skin cancers. By targeting and destroying abnormal, rapidly growing skin cells, this medication helps clear these lesions and allows healthy skin to grow back.

For the best results, you must apply it consistently and exactly as your doctor prescribes, usually once or twice daily. Ensure your skin is completely clean and dry before application. Making simple daily changes, such as wearing wide-brimmed hats and protective clothing, is highly recommended to protect your healing skin from sun damage.

While using this, it is normal to experience redness, dryness, peeling, and mild burning at the application site. However, if you notice severe pain, swelling, oozing, or signs of infection like pus, you should contact your doctor right away.

Before starting treatment, tell your doctor if you have a known genetic condition called dihydropyrimidine dehydrogenase (DPD) deficiency, as this can lead to severe side effects. Do not use this medicine if you are pregnant or planning to become pregnant, as it can cause serious harm to an unborn baby.

Avoid applying other skin products, cosmetics, or harsh soaps on the treated area, as they can cause severe irritation. If you are breastfeeding or are an older adult, talk to your doctor to ensure this treatment is safe for your specific situation.

Uses of Fluo 1% Cream

Your doctor may recommend this medication to help manage the following conditions:

  • Actinic Keratoses: This medicine helps by clearing rough, scaly patches on the skin that are pre-cancerous, preventing them from developing into skin cancer.
  • Superficial Basal Cell Carcinoma: This medicine helps by treating small, slow-growing skin cancers on the surface of the skin when surgical options are not preferred.

Key Benefits

It provides practical, real-world relief by offering a non-invasive way to manage skin health at home. Key benefits include:

  • Non-surgical treatment: It allows you to treat multiple skin lesions without the need for painful cutting or freezing procedures in a clinic.
  • Targets hidden spots: It actively identifies and treats early-stage abnormal skin cells that are not yet visible on the surface of your skin.
  • Promotes healthy skin regrowth: After the old, damaged cells peel away, it helps your skin renew itself with healthy, normal tissue.

Directions for Use

  • Follow your doctor’s instructions on the dosage and timing of this medication to ensure safety.
  • Apply a thin layer of the medicine onto the affected area as advised by the doctor.
  • Fluo 1% Cream is for external use only.
  • Do not cover the treated skin with dressings unless advised by the doctor.

How Fluo 1% Cream Works

Fluo 1% Cream belongs to a class of drugs called antimetabolites. When you apply it to your skin, it is absorbed by rapidly dividing cells, such as pre-cancerous and cancerous cells, much more than it is by healthy cells. Once inside these abnormal cells, the medicine blocks their ability to make DNA and RNA, which are essential for cell growth and survival. Without these building blocks, the abnormal cells cannot multiply and eventually die off, allowing healthy skin to grow back in their place.
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Alcohol

Consult your doctor

It is not known if alcohol affects Fluo 1% Cream. Please consult your doctor.

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Pregnancy

Unsafe

Do not use Fluo 1% Cream if you are pregnant or think you are pregnant. Consult your doctor immediately if you become pregnant whilst on treatment with Fluo 1% Cream.

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Breast Feeding

Unsafe

Do not use Fluo 1% Cream if you are breastfeeding. If use during breastfeeding is necessary, breastfeeding should be discontinued.

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Driving

Not applicable

Fluo 1% Cream does not affect your ability to drive.

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Liver

Consult your doctor

Please consult your doctor if you have a liver impairment or any concerns.

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Kidney

Consult your doctor

Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

Fluo 1% Cream is not recommended for children below 18 years.

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Heart

Safe if prescribed

Fluo 1% Cream is generally considered safe for heart patients. However, please consult your doctor if you have any concerns.

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Geriatrics

Safe if prescribed

Fluo 1% Cream is generally considered safe for geriatric patients. However, please consult your doctor if you have any concerns.

What if I have taken an overdose of Fluo 1% Cream

If you apply too much of this medicine or if someone accidentally swallows it, seek immediate medical attention.

Diet & Lifestyle Advise

  • Practice strict sun protection: Wear a wide-brimmed hat, long-sleeved shirts, and sunglasses whenever you go outdoors, as this medication makes your skin highly sensitive to sunlight.
  • Avoid artificial UV light: Stay away from tanning beds and sunlamps, which can trigger severe skin reactions during your treatment.
  • Stay well-hydrated: Drink plenty of water throughout the day to support your body's natural healing process as your skin sheds and renews itself.
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How Soon It Starts Working

The time required for Fluo 1% Cream to start to work: The exact onset time of Fluo 1% Cream has not been clinically established. The time for which the effects of Fluo 1% Cream last: The duration of Fluo 1% Cream’s effect is clinically not established.

What if you forget to take Fluo 1% Cream

Apply the missed dose as soon as you remember. If it is almost time for your next scheduled application, skip the missed one and continue with your regular schedule. Do not apply a double amount to make up for a missed dose.

Storage

• Store it at room temperature, ideally between 20°C and 25°C (68°F to 77°F).

Drug Warnings

  • Check before use: Inspect the tube or bottle before use; do not use if the seal is broken or if the cream has changed colour or texture.
  • Avoid damaged skin: Never apply this medication to irritated, broken, or peeling skin unless specifically instructed by your doctor.
  • Avoid contact with eyes and mouth: Be extremely careful not to touch your eyes, nose, or mouth after applying the medicine; if contact occurs, rinse thoroughly with plenty of water immediately. Seek medical advice if irritation, pain, redness, or vision changes continue after rinsing.
  • Do not share: Do not share this medication with anyone else, even if they have similar skin spots.
  • Keep away from pets: Keep treated skin away from pets, as even a small amount of this medication can be highly toxic and fatal to animals if they lick the area.
  • When to see your doctor: Contact your doctor if your symptoms worsen, you do not see improvement after completing the prescribed course, or new skin lesions appear.
  • During treatment: During treatment, the skin may become red, swollen, irritated, dry, or peel as the medicine works on abnormal skin cells. These reactions may gradually progress before healing begins after treatment is stopped.
  • Tell your doctor: Inform your doctor if you are receiving systemic Fluo 1% Cream (such as injections for cancer treatment) or using other skin treatments, as this may affect your treatment plan.

Drug-Drug Interactions

verifiedApollotooltip

  • Topical products: Applying other topical medicines, medicated cleansers, cosmetics, or skin peeling agents on the same area may increase skin irritation or affect how this medicine works.
  • Other medicines: Tell your doctor about all medicines you use, including blood thinners such as warfarin, as topical Fluo 1% Cream may rarely affect how some medicines work. 
No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

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  • No clinically significant food interactions are known with Fluo 1% Cream when used as directed.     
     
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[CHEMOTHERAPY]

FAQs

Fluo 1% Cream is used to treat Keratosis/multiple actinic or solar keratosis, some simple skin cancers, keratoacanthoma, Bowen’s disease, and superficial basal cell carcinoma.
Fluo 1% Cream works by destroying cancerous and pre-cancerous cells whilst having little effect on normal cells.
Fluo 1% Cream may impair male and female fertility. It is not recommended for men attempting to father a child. Talk to your doctor if you have any concerns.
Do not stop using Fluo 1% Cream on your own. Depending on your medical condition, you are advised to use Fluo 1% Cream for as long as your doctor has prescribed it. Do not be reluctant to speak with your doctor if you experience any difficulty while using Fluo 1% Cream.
No, Fluo 1% Cream is not a vesicant. It is classified as an irritant which can cause local inflammation and discomfort if it leaks outside the vein (extravasation). However, it does not cause the extensive tissue damage associated with vesicants.
Yes, Fluo 1% Cream is safe if it is used in the dose and duration prescribed by the doctor.
Yes, Fluo 1% Cream and efudex are the same in terms of their active ingredient. Efudex is the brand name for the topical formulation of Fluo 1% Cream that is used to treat skin conditions like actinic keratosis and superficial basal cell carcinoma. Fluo 1% Cream refers to the drug that exists in both intravenous and topic forms used for cancer treatment.
Fluo 1% Cream is not known to cause scarring. It is an effective treatment for problematic scars, including keloids and hypertrophic scars.
The side effects of Fluo 1% Cream include loss of appetite, nausea, vomiting, diarrhoea, hair loss, weakness, increased risk of infection, decreased blood cells, and mouth ulcers. Consult the doctor if any of these symptoms persist or worsen.
Daily application of Fluo 1% Cream to normal skin results in noticeable morphological changes in the epidermis.Therefore, Fluo 1% Cream can be used on normal skin only if prescribed by the doctor.
Yes, Fluo 1% Cream can be used for warts, particularly plantar warts. It works by disrupting abnormal cell growth in the wart, helping to remove it over time.
Yes, Fluo 1% Cream is a type of topical chemotherapy. It is commonly used to treat certain skin conditions, such as actinic keratosis and superficial basal cell carcinoma, by targeting and destroying abnormal or precancerous cells.
It is best to avoid applying cosmetics over the treated area during therapy, as they can irritate. Talk to your doctor for advice on your specific skin care routine.
You should avoid swimming, especially in chlorinated pools or saltwater, as this can irritate the treated skin and wash the medication off. Talk to your doctor for specific guidance.
This medication is extremely toxic to pets and can be fatal. If your pet licks the treated skin or swallows any of the medicine, contact a veterinarian immediately.
No, you must not use this medicine if you are pregnant or planning to become pregnant, as it can cause serious birth defects. Talk to your doctor immediately if you suspect you are pregnant.
No, you should leave the treated skin uncovered unless your doctor tells you otherwise. Covering the area can increase the absorption of the medicine and cause severe skin reactions. Talk to your doctor if you have questions.
You must avoid direct sun exposure as much as possible, as this medicine makes your skin highly sensitive to UV light. Wear protective clothing and talk to your doctor about safe sun protection options.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

Meldi Estate, Near Prasang Party Plot, Opp. Sola Bhagwat, Sayona City Road, Gota, Ahmedabad - 382481 Gujarat, (India)
Other Info - FLU0760
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