Intwelve D Tablet 10's
MRP ₹172
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About Intwelve D Tablet 10's
Intwelve D Tablet 10's is used in the treatment of neuropathic pain. Neuropathic pain is a chronic progressive nerve disease that causes nerve pain due to damage to sensory nerves. Symptoms include spontaneous, untriggered pain, unpleasant feelings, shooting, burning or stabbing pain, difficulty resting or sleeping.
Intwelve D Tablet 10's is a combination of alpha-lipoic acid, folic acid, methylcobalamin and pyridoxine. Methylcobalamin and pyridoxine help rejuvenate and protect damaged nerve cells. Alpha-lipoic acid helps in providing a protective effect on the nerve tissues and the brain. Folic acid helps in providing essential nutrients to the nerves. Vitamin D3 helps in the absorption of calcium.
Sometimes, you may experience common side effects such as nausea, headache, vomiting and heartburn. Most of these side effects do not require medical attention and will resolve gradually. However, talk to your doctor if you experience these side effects persistently.
Avoid taking Intwelve D Tablet 10's if you are allergic to any other drugs or other components present in it. Consult your doctor before using Intwelve D Tablet 10's if you are pregnant or breastfeeding. Intwelve D Tablet 10's is not recommended for children as safety and efficacy have not been established. Avoid consuming alcohol along with Intwelve D Tablet 10's as it could lead to unpleasant side effects.
Uses of Intwelve D Tablet 10's
Intwelve D Tablet 10's is used in the treatment of nerve damage. The detailed uses of Intwelve D Tablet 10's are as follows:
- Neuropathy Treatment: Intwelve D Tablet 10's helps alleviate peripheral neuropathy symptoms like pain, numbness, and tingling in the extremities.
- Vitamin Deficiency: Intwelve D Tablet 10's addresses deficiencies in essential B vitamins, which can lead to various neurological issues.
- Support for Neurological Conditions: Intwelve D Tablet 10's supports neurological health by providing essential B vitamins for nerve function and management of related disorders.
- Pain Relief: helps alleviate neuropathic pain, including lower back and leg pain, associated with conditions like diabetes or vitamin B12 deficiency.
- Improving Nerve Health: Supports nerve health by aiding in the regeneration and repair of damaged nerves, enhancing overall nerve function.
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Directions for Use
- Intwelve D Tablet 10's can be taken with or without food as advised by the doctor.
- Take Intwelve D Tablet 10's once daily, or as recommended by your doctor, ideally at the same time each day for consistent results.
- Swallow Intwelve D Tablet 10's as a whole with a glass of water.
- Do not crush, chew, or break it.
Key Benefits
- Intwelve D Tablet 10's is a combination of five drugs: Alpha-lipoic acid, folic acid, mecobalamin, pyridoxine and vitamin D3. Intwelve D Tablet 10's is used to treat nutritional deficiency.
- Alpha-lipoic acid is an antioxidant that helps provide a protective effect on the nerve tissues and the brain.
- Folic acid is a vitamin that helps in providing essential nutrients to nerves. It is also very useful in producing healthy red blood cells.
- Mecobalamin helps in the rejuvenation and protection of damaged nerve cells by producing a substance called myelin. It is also essential in red blood cell formation and helps in maintaining blood circulation and nerve function.
- Pyridoxine is useful in facilitating myelin and neurotransmitter synthesis. Pyridoxine also aids in the production of healthy blood cells.
- Vitamin D3, an active form of vitamin D, is essential for the absorption of calcium.
- Intwelve D Tablet 10's is used for the treatment of various health problems like a weak immune system, skin problems, digestive problems, defective bone growth, and neurological diseases.
How Intwelve D Tablet 10's Works
Storage
- Skin rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
- Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
- Protect your skin from extreme heat and try to apply wet compresses.
- Soak in the cool bath, which gives a soothing impact to the affected area.
- Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
- Divide your daily food intake into smaller, more frequent meals to reduce nausea.
- Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
- Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
- Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
- Use ginger (tea, ale, or candies) to help relieve nausea.
- Get adequate rest and also avoid strenuous activities that can worsen nausea.
- Talk to your doctor about taking anti-nausea medication if your nausea is severe.
- Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
What if I have taken an overdose of Intwelve D Tablet 10's
Drug Warnings
- Inform your doctor if you are allergic to any of the components of Intwelve D Tablet 10's.
- Notify your doctor if you have malabsorption syndrome (difficulty absorbing nutrition from food).
- Pregnant or breastfeeding women should consult their doctor before taking Intwelve D Tablet 10's.
- Excessive alcohol consumption reduces absorption and increases the elimination of folic acid. Hence, please avoid alcohol while using Intwelve D Tablet 10's.
- Intwelve D Tablet 10's is not recommended for children as safety and efficacy have not been established.
- Exercise caution while using Intwelve D Tablet 10's with anti-tumour drugs, antibiotics, chemotherapy, anti-diabetic drugs, thyroid hormone and blood thinners.
Inform your doctor if you are due to undergo any surgery.
Drug-Drug Interactions
Drug-Drug Interactions
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Cholecalciferol and doxercalciferol are forms of vitamin D, and taking too much vitamin D may lead to toxic effects.
How to manage the interaction:
Although there is a possible interaction between Intwelve D Tablet and doxercalciferol, you can take these medicines together if prescribed by your doctor. If you notice any of these symptoms - irregular heartbeat, seizures, weakness, tiredness, headache, dizziness, ringing in the ears, loss of appetite, feeling sick, dry mouth, strange taste in your mouth, muscle or bone pain, thirst, losing weight, eye infection, sensitivity to light, runny nose or itching - make sure to call a doctor right away. Do not discontinue any medications without consulting a doctor.
Taking Cholecalciferol together with Sucralfate may increase the risk or severity of kidney problems.
How to manage the interaction:
There may be a possibility of interaction between Cholecalciferol and Sucralfate, but it can be taken if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
The combined use of calcifediol with cholecalciferol can increase the risk of side effects.
How to manage the interaction:
Although there is a possible interaction between Intwelve D Tablet and calcifediol, you can take these medicines together if prescribed by your doctor. If you notice any of these symptoms - irregular heartbeat, seizures, weakness, tiredness, headache, dizziness, ringing in the ears, loss of appetite, feeling sick, dry mouth, strange taste in your mouth, muscle or bone pain, thirst, losing weight, eye infection, sensitivity to light, runny nose or itching - contact a doctor right away. Do not discontinue any medications without consulting a doctor.
Cholecalciferol and dihydrotachysterol are forms of vitamin D, and taking too much vitamin D may lead to toxic effects.
How to manage the interaction:
Although there is a possible interaction between Intwelve D Tablet and dihydrotachysterol, you can take these medicines together if prescribed by your doctor. If you notice any of these symptoms - irregular heartbeat, seizures, weakness, tiredness, headache, dizziness, ringing in the ears, loss of appetite, feeling sick, dry mouth, strange taste in your mouth, muscle or bone pain, thirst, losing weight, eye infection, sensitivity to light, runny nose or itching - contact a doctor right away. Do not discontinue any medications without consulting a doctor.
Co-administration of Cholecalciferol and Calcitriol are forms of vitamin D, and taking too much vitamin D may lead to toxic effects.
How to manage the interaction:
Although there is a possible interaction between Intwelve D Tablet and calcitriol, you can take these medicines together if prescribed by your doctor. If you notice any of these symptoms - irregular heartbeat, seizures, weakness, tiredness, headache, dizziness, ringing in the ears, loss of appetite, feeling sick, dry mouth, strange taste in your mouth, muscle or bone pain, thirst, losing weight, eye infection, sensitivity to light, runny nose or itching - contact a doctor right away. Do not discontinue any medications without consulting a doctor.
The combined use of aluminum hydroxide with Intwelve D Tablet may increase the risk of toxicity.
How to manage the interaction:
Co-administration of Intwelve D Tablet with Aluminium hydroxide can possibly result in an interaction, but it can be taken if your doctor has advised it. If you're having any of these symptoms like bone pain, muscle weakness, anemia, seizures, or dementia, it's important to contact your doctor right away. Do not stop using any medications without a doctor's advice.
The combined use of cholecalciferol and ergocalciferol are forms of vitamin D, and taking too much vitamin D may lead to toxic effects.
How to manage the interaction:
Although there is a possible interaction between Intwelve D Tablet and ergocalciferol, you can take these medicines together if prescribed by your doctor. If you notice any of these symptoms - irregular heartbeat, seizures, weakness, tiredness, headache, dizziness, ringing in the ears, loss of appetite, feeling sick, dry mouth, strange taste in your mouth, muscle or bone pain, thirst, losing weight, eye infection, sensitivity to light, runny nose or itching - contact a doctor right away. Do not discontinue any medications without consulting a doctor.
The combined use of cholecalciferol and paricalcitol are forms of vitamin D, and taking too much vitamin D may lead to toxic effects.
How to manage the interaction:
Although there is a possible interaction between Intwelve D Tablet and paricalcitol, you can take these medicines together if prescribed by your doctor. If you notice any of these symptoms - irregular heartbeat, seizures, weakness, tiredness, headache, dizziness, ringing in the ears, loss of appetite, feeling sick, dry mouth, strange taste in your mouth, muscle or bone pain, thirst, losing weight, eye infection, sensitivity to light, runny nose or itching - contact a doctor right away. Do not discontinue any medications without consulting a doctor.
Co-administration of Intwelve D Tablet with Capecitabine may increase the risk of serious side effects such as bleeding problems, anemia, infections, and nerve damage.
How to manage the interaction:
Although there is a possible interaction between Intwelve D Tablet and Capecitabine, you can use these medicines together if prescribed by the doctor. However, if you experience paleness of skin, diarrhea, severe nausea and vomiting, over-tiredness, dizziness, fainting, blood in the stools, unusual bleeding or bruising, fever, chills, body aches, flu-like symptoms, skin reactions, mouth ulcers or sores, and/or numbness, burning or tingling sensation in the hands and feet, contact a doctor. Do not discontinue the medication without consulting a doctor. Do not discontinue the medication without consulting a doctor.
Coadministration of Intwelve D Tablet and Cholestyramine may interfere with the absorption of Intwelve D Tablet.
How to manage the interaction:
Although taking Cholestyramine and Intwelve D Tablet together can result in an interaction, they can be taken together if prescribed by a doctor. However, if you experience Constipation, Diarrhea, Stomach pain, Nausea, or Loss of appetite, consult a doctor. Do not stop using any medications without consulting a doctor.
Drug-Food Interactions
Drug-Food Interactions
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Diet & Lifestyle Advise
- Try Vitamin B complex food sources like milk, cheese, eggs, liver, kidney, chicken, red meat, tuna, mackerel, salmon, shellfish, oysters, clams, dark green vegetables such as spinach and kale, beets, avocados, potatoes, whole grains, cereals, kidney beans, black beans, and chickpea.
- Try folate-rich food sources like broccoli, Brussels sprouts, leafy green vegetables, cabbage, kale, spring greens, spinach, peas, chickpeas, kidney beans, and breakfast cereals fortified with folic acid.
- Include the best dietary sources of vitamin D, such as fish liver oils and vitamin D–fortified milk.
- Include dairy products like milk, yoghurt, cheese, or milk-based custard in your diet.
- Include fruits like citrus, banana, and watermelon in your diet.
- Avoid smoking and alcohol consumption.
- Exercise regularly and maintain a healthy lifestyle. Avoid excess fatty foods.
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Alcohol
Safe if prescribed
It is advised to limit/avoid alcohol intake to ensure maximum absorption of nutrients.
Pregnancy
Consult your doctor
Consult your doctor before taking Intwelve D Tablet 10's, your doctor will decide whether Intwelve D Tablet 10's can be taken by pregnant women or not.
Breast Feeding
Consult your doctor
Consult your doctor before taking Intwelve D Tablet 10's, your doctor will decide whether Intwelve D Tablet 10's can be taken by breastfeeding mothers or not.
Driving
Safe if prescribed
It is unknown if Intwelve D Tablet 10's affects your ability to drive. Do not drive or operate machinery unless you are alert.
Liver
Consult your doctor
Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.
Kidney
Consult your doctor
Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.
Children
Safe if prescribed
Intwelve D Tablet 10's should not be given to children as paediatric safety and efficacy have not been established.
Heart
Intwelve D Tablet 10's is usually safe for individuals with heart problems when taken in the recommended dose. However, consult your doctor if you have any concerns or underlying heart issues.
Geriatrics
Consult your doctor
Intwelve D Tablet 10's should be given to elderly patients only if recommended by a doctor. If you have any concerns, please consult your doctor.
FAQs
Intwelve D Tablet 10's is primarily used to treat nerve damage and manage nutritional deficiency.
Intwelve D Tablet 10's is a combination of five drugs: Alpha-lipoic acid, folic acid, mecobalamin, pyridoxine and vitamin D. When you lack these vitamins in your body, which cannot be recovered even with food sources, Intwelve D Tablet 10's helps replenish these deficient levels. Collectively, Intwelve D Tablet 10's treats nutritional deficiencies.
To treat your condition effectually, continue taking Intwelve D Tablet 10's for as long as recommended. Do not be reluctant to speak with your doctor if you feel any difficulty while taking Intwelve D Tablet 10's.
Pyridoxine in Intwelve D Tablet 10's may interfere with laboratory tests like urine tests for urobilinogen. Please make sure your doctor and the laboratory staff know that you take Intwelve D Tablet 10's before undergoing blood and urine examinations.
If you miss a dose, take it as soon as you remember. However, if it is time for the next scheduled dose, skip the missed dose and follow your usual dosage.
Intwelve D Tablet 10's can be taken daily or as advised by the physician. Talk to the doctor if you have any concerns.
Intwelve D Tablet 10's should be taken as recommended by the doctor. Take it as per the dose and duration advised by the doctor.
Intwelve D Tablet 10's may cause side effects such as nausea, headache and vomiting. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
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Reference
- https://www.webmd.com/vitamins/ai/ingredientmono-767/alpha-lipoic-acid
- https://www.ncbi.nlm.nih.gov/books/NBK441923/
- https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/021446s026,022488s005lbl.pdf
- https://www.npra.gov.my/images/reg-and-noti/PI/non-poison/Mecobalamin-Template-oral-Website.pdf
- https://www.fda.gov/media/116317/download
- https://www.nhs.uk/medicines/folic-acid/
- https://www.ncbi.nlm.nih.gov/books/NBK557436/
