How does Nise Gel work?

Nise Gel is a combination of fourÃ‚ painkillers/analgesics: Nimesulide, Capsaicin, Methyl salicylateÃ‚ and one cooling agent (Menthol). Nimesulide and Methyl salicylate works by blocking the release of certain chemical messengers in the brain responsible for causing pain and symptoms of inflammation such as redness and swelling. Capsaicin works by affecting the chemical messenger in the brain (neurotransmitter) that transmits pain signals to the brain, thereby reducing the perception of pain. Menthol acts as a cooling agent that relieves pain initially by cooling the skin, followed by warming it up. Cooling and warming up distracts from the pain and helps improve blood circulation.

In which conditions should I avoid using Nise Gel?

You are recommended to avoid using Nise Gel if you have had any recent bypass heart surgery, heart attack, stroke, gastrointestinal bleeding (bloody stool), or ulcer of the stomach or intestine. Elderly (more than 65 years of age) or smokers are at greater risk of having gastrointestinal bleeding, so they should use Nise Gel with caution.

Can I apply Nise Gel on wounds?

No, you are not recommended to apply Nise Gel on wounds, cuts, burn, rash, infected areas or peeling skin. However, please consult a doctor before using Nise Gel.

Does Nise Gel cause skin irritation?

Yes, Nise Gel may cause skin irritation at the site of application as a common side effect. It is not necessary for everyone using Nise Gel to experience this side effect. However, if the irritation persists or worsens, please consult a doctor.

Is Nise Gel safe for heart failure patients?

Patients with heart failure are not advised to take Nise Gel because painkillers may alter blood substance levels and make blood clots more likely. These blood clots have the potential to block and constrict your heart's artery, leading to a heart attack.

Can I take shower immediately after applying Nise Gel?

You are recommended to take a shower, bathe or wash the treated area of skin after 1 hour of applying Nise Gel for effective results.

Does Nise Gel cure arthritis?

No, Nise Gel does not cure arthritis. Nise Gel is only used to relieve symptoms of arthritis-like joint pain, swelling and stiffness.

Nise Gel is for external use only. Take a small amount of Nise Gel on the finger and apply as a thin layer on the clean and dry affected area and surrounding skin. Avoid contact with the eyes, mouth, or nose. If accidental contact occurs, rinse thoroughly with water. Be sure to wash your hands before and after application.

Is Nise Gel a steroid?

No, Nise Gel, is not a steroid. It belongs to the class of medicines called Non-Steroidal Anti-Inflammatory Drugs (NSAIDs).

What precautions do I need to take while using Nise Gel?

While using Nise Gel, you are recommended to tell your doctor if you are allergic to the active substances of Nise Gel and if you have kidney, liver, or heart disease, diabetes, asthma, high blood pressure, bleeding in the stomach or intestines, stomach ulcers, and edema. Avoid using Nise Gel on cuts, wounds, or damaged skin. Avoid consuming alcohol while using it to reduce the risk of stomach bleeding. Do not apply heat or tightly wrap the treated area. Use only as directed, and avoid excessive or prolonged application to prevent adverse effects.

What should I do if I forget to use Nise Gel?

If you forget to use Nise Gel, then apply as soon as you remember. Avoid applying more to make up for the missed one. If you have any concerns, contact your doctor.

Can I stop using Nise Gel when I feel better?

You are not recommended to stop using Nise Gel without consulting your doctor, even if you feel better as stopping early might affect the treatment's effectiveness. Always follow your doctor’s instructions.

Nise Gel is generally safe for most patients when used as per the dose and duration advised by a doctor. Follow the instructions given by your doctor. Do not self-medicate.

Is Nise Gel an antibiotic?

No, Nise Gel is not an antibiotic. It contains capsaicin, menthol methyl salicylate, and nimesulide as its active substances, used to relieve pain and inflammation associated with conditions like muscle aches, joint pain, and sprains.

Can I take Nise Gel with paracetamol?

Both Nise Gel and paracetamol are pain-relieving medications. Using them together is generally not advised, as it may raise the risk of gastric ulcers and bleeding. It is essential to consult your doctor before taking Nise Gel with paracetamol or other medicines.

Does Nise Gel contain aspirin?

No, Nise Gel does not contain aspirin.

Can I take Nise Gel for headache?

Nise Gel may be used for headaches, but only when prescribed by a doctor. It has been shown to help with mild migraines and can be effective for headaches when used as directed. However, it is not recommended for long-term use in cases of recurring headaches. If you experience frequent headaches, consult your doctor for proper treatment.

Does Nise Gel make you drowsy (feeling sleepy)?

Nise Gel does not cause drowsiness as it works locally and applied to the skin. Nise Gel active ingredients work directly on the area to relieve pain. Inform your doctor if your symptoms worsen while using Nise Gel.

Can I take Nise Gel with ibuprofen?

You are recommended to consult your doctor before using Nise Gel with other medicines.

Can I take Nise Gel with aspirin?

Nise Gel may be taken with aspirin as no interactions have been observed. However, please consult a doctor before using Nise Gel with aspirin or other medicines to avoid potential interactions.

No, Nise Gel is not banned in India.

Is Nise Gel safe during breastfeeding?

It is unknown if Nise Gel passes into breast milk and if it can harm the baby. Therefore, consult a doctor before using Nise Gel if you are breastfeeding.

Is Nise Gel safe in pregnancy?

You are recommended to take a doctor’s advice before using Nise Gel if you are pregnant or planning for pregnancy.

Is Nise Gel safe in asthma?

Nise Gel may be safe for asthma patients. However, it's advisable to inform your doctor if you have a history of asthma. Do not self-medicate.

What are the side effects of Nise Gel?

Nise Gel causes side effects such as irritated skin, burning sensation, stinging sensation, red skin or rashes, erythema (redness of skin or mucous membranes), and desquamation (peeling skin). Consult your doctor if these side effects persist or worsen.

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Written By Lakshmithulasi Yarragunta ,

Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Nise Gel is used to treat musculoskeletal pain. It works by blocking the release of certain chemicals that cause pain and inflammation and inhibiting the transmission of pain signals to the brain. In some cases, this medicine may cause side effects such as redness, itching, irritation or a burning sensation at the site of application. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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About Nise Gel

Nise Gel belongs to a class of medications called 'topical analgesic' (pain killer) primarily used to relieve joint pain, low back pain, muscle sprain and sports injuries. Besides this, it also reduces pain and swelling in muscles and joints in the conditions of joint disorders like osteoarthritis and rheumatoid arthritis. Arthritis is a condition that causes swelling of one or more joints resulting in pain and stiffness of joints that worsen over time.

Nise Gel is a combination of four painkillers/analgesics: Nimesulide, Capsaicin, Methyl salicylate and one cooling agent (Menthol). Nimesulide and Methyl salicylate belong to the class of non-steroidal anti-inflammatory drug (NSAIDs) or painkillers that works by blocking the release of certain chemical messengers in the brain responsible for causing pain and symptoms of inflammation such as redness and swelling. Capsaicin is an analgesic that works by affecting the chemical messenger in the brain (neurotransmitter) that transmits pain signals to the brain, thereby reducing the perception of pain. Menthol acts as a cooling agent that relieves pain initially by cooling the skin, followed by warming it up. This action of cooling and warming up distracts from the pain and helps improve blood circulation.

Nise Gel is only for external use. Take a small amount of Nise Gel on the finger and apply it as a thin layer on the clean and dry affected area. Avoid contact of Nise Gel with nose, ears, mouth or eyes. If Nise Gel comes in contact with these areas accidentally, rinse with water thoroughly. Your doctor will advise you how often you use Nise Gel based on your medical condition. In some cases, you may experience redness, itching, irritation or a burning sensation at the site of application. Most of these side effects of Nise Gel do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are known to be allergic to Nise Gel or any other medicines, please tell your doctor. If pregnant or breastfeeding, please inform your doctor before taking Nise Gel. Do not consume alcohol with Nise Gel as it may increase the risk of stomach bleeding. Do not apply heat or wrap the treated area of the skin with bandages. Avoid using Nise Gel in more than prescribed doses or on a large area of skin for a prolonged time, as it may cause adverse effects. Do not apply Nise Gel on cuts, wounds or damaged skin. If you have asthma, high blood pressure, diabetes, blood clots, bleeding in the stomach or intestines, stomach ulcers, oedema (swelling due to fluid retention or overload), liver, kidney or heart problems, inform your doctor before taking Nise Gel.

Uses of Nise Gel

Treatment of Musculoskeletal pain

Directions for Use

• Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.• Take a small amount of Nise Gel on the fingertip and apply it as a thin layer on the clean and dry affected area as advised by your doctor.• Nise Gel is only for external use. Avoid contact of the Nise Gel with the nose, mouth or eyes. In case of accidental contact with these areas, rinse with water thoroughly.

Medicinal Benefits

Nise Gel is a combination of three painkillers/analgesics (Nimesulide, Capsaicin, Methyl salicylate) and one cooling agent (Menthol). Nimesulide and Methyl salicylate belong to the class of non-steroidal anti-inflammatory drug (NSAIDs) or painkillers that works by blocking the release of certain chemical messengers in the brain responsible for causing pain and symptoms of inflammation such as redness and swelling. Capsaicin is an analgesic that works by affecting the chemical messenger in the brain (neurotransmitter) that transmits pain signals to the brain, thereby reducing the perception of pain. Menthol acts as a cooling agent that relieves pain initially by cooling the skin, followed by warming it up. Cooling and warming up distracts from the pain and helps improve blood circulation.

How Nise Gel Works

Nise Gel is a combination of four painkillers/analgesics: Nimesulide, Capsaicin, Methyl salicylate and one cooling agent (Menthol). Nimesulide and Methyl salicylate belong to the class of non-steroidal anti-inflammatory drug (NSAIDs) or painkillers that works by blocking the release of certain chemical messengers in the brain responsible for causing pain and symptoms of inflammation such as redness and swelling. Capsaicin is an analgesic that works by affecting the chemical messenger in the brain (neurotransmitter) that transmits pain signals to the brain, thereby reducing the perception of pain. Menthol acts as a cooling agent that relieves pain initially by cooling the skin, followed by warming it up. This action of cooling and warming up distracts from the pain and helps improve blood circulation.

Storage

Store in a cool and dry place away from sunlight

What if I have taken an overdose of Nise Gel

Avoid exceeding the recommended dose as it might cause an overdose. Seek immediate medical attention if you experience any unusual symptoms.

Drug Warnings

If you are known to be allergic to Nise Gel or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, please inform your doctor before taking Nise Gel. Do not consume alcohol with Nise Gel as it may increase the risk of stomach bleeding. Do not apply heat or wrap the treated area of the skin with bandages. Avoid using Nise Gel in more than prescribed doses or on a large area of skin for a prolonged time, as it may cause adverse effects. Do not apply Nise Gel on cuts, wounds or damaged skin. Wait for a minimum of 10 minutes before wearing clothes or gloves over the treated area. If you have asthma, high blood pressure, diabetes, blood clots, bleeding in the stomach or intestines, stomach ulcers, edema (swelling due to fluid retention), liver, kidney or heart problems, inform your doctor before taking Nise Gel.

Drug-Drug Interactions

No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

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Diet & Lifestyle Advise

Maintain a healthy body weight, as obesity may also cause joint pains. Please do not go for heavy exercise as it may increase your joint pain in arthritis. Instead, you can do stretching, low impact aerobic exercises like walking on a treadmill, bike riding and swimming. You can also strengthen your muscle strength by lifting light weights.
Include more glucosamine, chondroitin sulfate, Vitamin D, and calcium-enriched supplements. Besides this, turmeric and fish oils can help reduce inflammation in the tissue.
In the chronic conditions of arthritis or joint pain, fish like salmon, trout, tuna and sardines. These fishes are enriched with omega-3 fatty acids, which help in reducing inflammation (redness and swelling) and protect the heart.
Your sitting posture is important, especially when you have pain and inflammation. Try to sit as little as possible and only for a short time (10-15 min). Use back support like a rolled-up towel at the back of your curve to minimize pain. Besides this, you can use a footrest if required.
Avoid consumption of alcohol and quit smoking.

Habit Forming

No

Therapeutic Class

ANALGESICS