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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy

Ossivite 500 Tablet is used to treat low blood calcium levels. It contains Calcium and Cholecalciferol (Vitamin D3), which provide essential nutrients for maintaining bone formation and health. In some cases, it may cause side effects like constipation and stomach upset. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Manufacturer/Marketer :

Pfizer Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Ossivite 500 Tablet

Ossivite 500 Tablet is used to treat various conditions caused by low calcium levels in the body, like Vitamin D deficiency, osteoporosis (weak and brittle bones), hypoparathyroidism (parathyroid glands make low levels of calcium in the body), latent tetany (a muscle disease), and rickets or osteomalacia (softening or deforming of bones).

Ossivite 500 Tablet contains Calcium (mineral) and Cholecalciferol (Vitamin D3). Calcium provides essential nutrients to support bone formation and maintenance. Cholecalciferol helps maintain blood calcium and phosphorus levels, as well as bone mineralisation.

Ossivite 500 Tablet is likely safe to consume. In some cases, it may cause side effects like constipation and stomach upset. These side effects do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, consult your doctor.

If you are known to be allergic to Ossivite 500 Tablet or its inactive components, inform your doctor. Pregnant or breastfeeding women should consult their doctor before taking Ossivite 500 Tablet . Let your doctor know if you are taking any other medicines to prevent potential interactions.

Uses of Ossivite 500 Tablet

Ossivite 500 Tablet is indicated for the prevention and treatment of various conditions caused by calcium and vitamin D deficiency. The detailed uses of Ossivite 500 Tablet are as follows: <br/>• Treatment of Osteoporosis: Helps strengthen bones and reduce the risk of fractures in people with brittle or porous bones. <br/>• Management of Osteomalacia (Rickets): Treats softening of the bones caused by vitamin D deficiency, especially in children (rickets) and adults (osteomalacia). <br/>• Correction of Vitamin D Deficiency: Corrects low levels of vitamin D in the body, which is essential for calcium absorption and bone health. <br/>• Treats Hypoparathyroidism: Manages calcium levels in patients with underactive parathyroid glands by improving calcium absorption. <br/>• Manages Latent Tetany: Prevents and treats muscle cramps and spasms caused by low calcium levels in the blood. <br/>

Directions for Use

  • Take Ossivite 500 Tablet with food or as advised by the doctor.
  • Follow your doctor's instructions regarding the dosage and duration for effective results.
  • Swallow Ossivite 500 Tablet as a whole with water.
  • Do not crush, chew or break it.

Medicinal Benefits

  • Ossivite 500 Tablet is a combination of Calcium and Cholecalciferol (Vitamin D3) used to treat and prevent various conditions caused by calcium and vitamin D deficiency.
  • It helps maintain adequate calcium levels in the blood, essential for healthy bones, muscles, and nerves.
  • Ossivite 500 Tablet strengthens bones and teeth, reducing the risk of fractures in conditions like osteoporosis and osteomalacia.
  • It aids in the proper absorption of calcium and phosphorus from the intestine, correcting vitamin D deficiency.
  • Ossivite 500 Tablet helps regulate calcium levels in patients with underactive parathyroid glands, which are responsible for calcium balance.
  • It alleviates muscle cramps, twitching, and spasms caused by low calcium levels in the body.
  • Ossivite 500 Tablet also promotes healthy bone development and prevents bone deformities in people suffering from rickets.

How Ossivite 500 Tablet Works

Ossivite 500 Tablet contains Calcium (mineral) and Cholecalciferol (Vitamin D3). Calcium provides essential nutrients to support bone formation and maintenance. Cholecalciferol helps maintain blood calcium and phosphorus levels, as well as bone mineralisation.

Storage

Store in a cool and dry place away from sunlight

What if I have taken an overdose of Ossivite 500 Tablet

Do not exceed the recommended dose. Taking more than the advised amount will not enhance the effectiveness of the medicine and may lead to serious side effects or overdose-related complications. If you suspect an overdose, seek immediate medical attention.

Drug Warnings

  • Do not take Ossivite 500 Tablet if you are allergic to any of its components.
  • Ossivite 500 Tablet is not recommended if you have hypercalcaemia (high calcium levels), hypervitaminosis D (high vitamin D levels), and malabsorption syndrome (difficulty absorbing nutrition from food).
  • Brief your medical history if you have any heart, kidney, liver, blood vessel diseases, kidney stones, sarcoidosis (growth of inflammatory cells in different parts of the body), Crohn's disease (inflammatory bowel disease), Whipple's disease (bacterial infection affecting joints and digestive system), achlorhydria (little or no stomach acid), low levels of bile, or phosphate imbalance.
  • Drinking alcohol may affect calcium absorption; therefore, it is advised to limit alcohol intake while using Ossivite 500 Tablet .

Drug-Drug Interactions

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Calcium carbonatePatiromer calcium
Severe

Drug-Drug Interactions

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Calcium carbonatePatiromer calcium
Severe
How does the drug interact with Ossivite 500 Tablet:
Co-administration of Ossivite 500 Tablet may lower the effectiveness of Patiromer calcium in binding potassium.

How to manage the interaction:
Although there is an interaction, Ossivite 500 Tablet can be taken with Patiromer calcium if prescribed by the doctor. Consult the prescriber if you experience symptoms such as metabolic alkalosis like nausea, vomiting, tremor, muscle twitching, lightheadedness, numbness or tingling, prolonged muscle spasms, slowed breathing, irregular heartbeat, and confusion. Do not discontinue the medication without a doctor's advice.
How does the drug interact with Ossivite 500 Tablet:
Co-administration of Ossivite 500 Tablet and Digoxin may increase the calcium levels may increase the effects of Digoxin

How to manage the interaction:
Although there is an interaction, Ossivite 500 Tablet can be taken with Digoxin if prescribed by the doctor. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Ossivite 500 Tablet:
Co-administration of Ossivite 500 Tablet may interfere with the absorption of Raltegravir and reduce its effectiveness.

How to manage the interaction:
Taking Ossivite 500 Tablet with Raltegravir should be avoided. Consult the doctor if you have any concerns, the doctor may recommend alternatives that do not interact with raltegravir. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Ossivite 500 Tablet:
Co-administration of Dolutegravir with Ossivite 500 Tablet can reduce the effectiveness of dolutegravir.

How to manage the interaction:
Although there is an interaction, Ossivite 500 Tablet can be taken with dolutegravir if prescribed by the doctor. However, dolutegravir and Ossivite 500 Tablet should not be taken orally at the same time. Maintain a gap of 2-6 hours between both medicines. Do not discontinue using any medications without consulting a doctor.
How does the drug interact with Ossivite 500 Tablet:
Co-administration of Ossivite 500 Tablet may interfere with the absorption of Gefitinib and reduce its effectiveness.

How to manage the interaction:
Although there is an interaction, Ossivite 500 Tablet can be taken with Gefitinib if prescribed by the doctor. However, Gefitinib and Ossivite 500 Tablet should not be taken orally at the same time. Maintain a gap of 2-6 hours between both medicines. Do not discontinue using any medications without consulting a doctor.
How does the drug interact with Ossivite 500 Tablet:
Co-administration of Ossivite 500 Tablet with Ketoconazole may decrease the effects of Ketoconazole.

How to manage the interaction:
Although there is an interaction, Ossivite 500 Tablet can be taken with Ketoconazole if prescribed by the doctor. However, maintain a gap of 2 or more hours between both medicines. Do not discontinue the medication without consulting a doctor.
ColecalciferolDihydrotachysterol
Severe
How does the drug interact with Ossivite 500 Tablet:
Cholecalciferol and dihydrotachysterol are forms of vitamin D, and taking too much vitamin D may lead to toxic effects.

How to manage the interaction:
Although there is a possible interaction between Ossivite 500 Tablet and dihydrotachysterol, you can take these medicines together if prescribed by your doctor. If you notice any of these symptoms - irregular heartbeat, seizures, weakness, tiredness, headache, dizziness, ringing in the ears, loss of appetite, feeling sick, dry mouth, strange taste in your mouth, muscle or bone pain, thirst, losing weight, eye infection, sensitivity to light, runny nose or itching - contact a doctor right away. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Ossivite 500 Tablet:
Cholecalciferol and doxercalciferol are forms of vitamin D, and taking too much vitamin D may lead to toxic effects.

How to manage the interaction:
Although there is a possible interaction between Ossivite 500 Tablet and doxercalciferol, you can take these medicines together if prescribed by your doctor. If you notice any of these symptoms - irregular heartbeat, seizures, weakness, tiredness, headache, dizziness, ringing in the ears, loss of appetite, feeling sick, dry mouth, strange taste in your mouth, muscle or bone pain, thirst, losing weight, eye infection, sensitivity to light, runny nose or itching - make sure to call a doctor right away. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Ossivite 500 Tablet:
Co-administration of Cholecalciferol and Calcitriol are forms of vitamin D, and taking too much vitamin D may lead to toxic effects.

How to manage the interaction:
Although there is a possible interaction between Ossivite 500 Tablet and calcitriol, you can take these medicines together if prescribed by your doctor. If you notice any of these symptoms - irregular heartbeat, seizures, weakness, tiredness, headache, dizziness, ringing in the ears, loss of appetite, feeling sick, dry mouth, strange taste in your mouth, muscle or bone pain, thirst, losing weight, eye infection, sensitivity to light, runny nose or itching - contact a doctor right away. Do not discontinue any medications without consulting a doctor.
ColecalciferolParicalcitol
Severe
How does the drug interact with Ossivite 500 Tablet:
The combined use of cholecalciferol and paricalcitol are forms of vitamin D, and taking too much vitamin D may lead to toxic effects.

How to manage the interaction:
Although there is a possible interaction between Ossivite 500 Tablet and paricalcitol, you can take these medicines together if prescribed by your doctor. If you notice any of these symptoms - irregular heartbeat, seizures, weakness, tiredness, headache, dizziness, ringing in the ears, loss of appetite, feeling sick, dry mouth, strange taste in your mouth, muscle or bone pain, thirst, losing weight, eye infection, sensitivity to light, runny nose or itching - contact a doctor right away. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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CALCIUM-500MG+CHOLECALCIFEROL-250IUFiber rich foods
Moderate

Drug-Food Interactions

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CALCIUM-500MG+CHOLECALCIFEROL-250IUFiber rich foods
Moderate
Common Foods to Avoid:
Spinach

How to manage the interaction:
Taking Ossivite 500 Tablet with food containing oxalic acid (e.g., spinach) or phytic acid (e.g., whole grains) can decrease the absorption of Ossivite 500 Tablet. It is advised to take Ossivite 500 Tablet 2 hours after or before consumption of food containing oxalic acid or phytic acid.

Diet & Lifestyle Advise

  • Include dairy products like milk, yoghurt, cheese or milk-based custard in your diet.
  • Eat daily a serving of broccoli, cabbage, bok choy, spinach and other green leafy vegetables.
  • Include the best dietary sources of vitamin D, such as fish liver oils and vitamin D-fortified milk.
  • Snack on calcium-rich nuts like Brazil nuts or almonds. 
  • Sprinkle sesame seeds over your food, vegetables and salads. Sesame seeds are high in calcium.
  • Avoid or reduce the intake of caffeine, soft drinks and alcohol that inhibit calcium absorption.
  • Replace the meat with tofu or tempeh for extra calcium in your food.

Habit Forming

No

Therapeutic Class

NUTRITIONAL SUPPLEMENT
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Alcohol

Caution

Drinking alcohol can affect calcium absorption, hence it is advised to limit alcohol intake while using Ossivite 500 Tablet .

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Pregnancy

Caution

Consult your doctor if you are pregnant. Your doctor will weigh the potential risks and benefits before recommending Ossivite 500 Tablet .

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Breast Feeding

Caution

Consult your doctor before taking Ossivite 500 Tablet if you are breastfeeding.

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Driving

Safe

Ossivite 500 Tablet is usually safe and does not interact with your driving ability.

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Liver

Consult your doctor

Let your doctor know if you have any history of liver disease before taking Ossivite 500 Tablet .

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Kidney

Caution

Seek doctor advice before starting Ossivite 500 Tablet if you have kidney diseases like kidney stones or are undergoing dialysis. Caution should be taken in patients undergoing dialysis before starting Ossivite 500 Tablet .

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Children

Consult your doctor

The doctor will decide the dosage of Ossivite 500 Tablet based on the child's age and weight.

Have a query?

FAQs

Ossivite 500 Tablet treats Osteoporosis, Osteomalacia (Rickets), Vitamin D deficiency, Hypoparathyroidism, and Latent tetany.

Ossivite 500 Tablet is a dietary supplement that treats low levels of calcium in the blood. It consists of Calcium and Cholecalciferol. Calcium is a mineral that prevents or treats calcium deficiency. Cholecalciferol, also known as Vitamin D3, helps maintain blood calcium and phosphorus levels and bone mineralisation. When you don't get enough Vitamin D from food sources and sunlight exposure, Ossivite 500 Tablet helps balance those low levels.

If you miss a dose, take it as soon as you remember. However, if it is time for the next scheduled dose, skip the missed dose and follow your usual dosage.

Milk is considered to be the best source of calcium. You can take Ossivite 500 Tablet with milk.

Ossivite 500 Tablet can cause kidney stones due to excess calcium deposition when used for a prolonged period. Please consult your doctor before taking Ossivite 500 Tablet as a daily supplement if you have any kidney problems or a history of kidney stones.

Ossivite 500 Tablet is used to increase low levels of calcium in the body. Hence, it is not advised to use Ossivite 500 Tablet during hypercalcaemia, since it causes the overdose of calcium, leading to kidney stones and other effects.

Antacids may increase the absorption of Calcium from Ossivite 500 Tablet . Hence, it is advised to take Ossivite 500 Tablet two hours before, or four hours after taking antacids.

It is generally recommended to take Ossivite 500 Tablet at night, before bedtime, as calcium absorption is better at night. However, follow your doctor's advice for optimal results.

Yes, Ossivite 500 Tablet is good for bones. It contains calcium and cholecalciferol, which are essential for maintaining bone health.

The common side effects of Ossivite 500 Tablet are constipation and stomach upset. These side effects do not require medical attention and gradually resolve over time. However, consult the doctor if the side effects persist or worsen.

Country of origin

India

Manufacturer/Marketer address

The Capital, 1802, 18th Floor , Plot No. C-70, ?G? Block , Bandra Kurla Complex, Bandra East , Mumbai ? 400051.
Other Info - OSS0035

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