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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Pegclear Oral Solution is used to treat constipation. It works by drawing water into the intestine, which softens the stools, making them easier to pass. In some cases, this medicine may cause side effects such as stomach pain, indigestion, mild diarrhoea, nausea, or vomiting. Before taking this medicine, inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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About Pegclear Oral Solution

Pegclear Oral Solution belongs to a class of drugs called laxatives, used to treat constipation. Constipation refers to infrequent bowel movements in which the stools are often dry, painful, and hard to pass.

Pegclear Oral Solution is a combination of four drugs, namely Polyethylene glycol, Potassium chloride, Sodium bicarbonate, and Sodium chloride. Polyethylene glycol draws water into the intestine and softens stools, making them easier to pass. Potassium chloride is essential for the healthy functioning of organs. Sodium bicarbonate works by neutralising high levels of acid in the stomach, helping to treat acidity and heartburn. Sodium chloride maintains sodium levels in the body. Together, Pegclear Oral Solution helps in relieving constipation.

Take Pegclear Oral Solution as advised by your doctor. In some cases, you may experience stomach pain, indigestion, mild diarrhoea, nausea, or vomiting. Most of these side effects of Pegclear Oral Solution do not require medical attention and typically resolve on their own over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Pegclear Oral Solution or any other medicines, please tell your doctor. If you have ulcerative colitis or Crohn’s disease, inform your doctor before taking Pegclear Oral Solution . Pegclear Oral Solution is not recommended for children below 12 years of age. If you are pregnant or breastfeeding, please consult a doctor before taking Pegclear Oral Solution . Drink plenty of fluids while taking Pegclear Oral Solution . Do not take Pegclear Oral Solution in more than the recommended doses.

Uses of Pegclear Oral Solution

Pegclear Oral Solution is used in the treatment of Constipation. The detailed uses of Pegclear Oral Solution are as follows:<br/>• Constipation relief: Pegclear Oral Solution helps retain water in the colon to soften stools and ease bowel movements.<br/>• Bowel cleansing: Pegclear Oral Solution used before medical procedures like colonoscopy to effectively clear the intestines.<br/>

Directions for Use

  • Pegclear Oral Solution can be taken with or without food, or as advised by your doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Check the label for directions. Dilute Pegclear Oral Solution with water as advised by your doctor. Take it orally using the measuring cup provided with the package.
  • Shake the bottle well before each use.

Medicinal Benefits

Pegclear Oral Solution contains Polyethylene glycol, Potassium chloride, Sodium bicarbonate and Sodium chloride. Polyethylene glycol draws water into the intestine and softens stools, making them easier to pass. Also, it works by cleaning the stool from the gastrointestinal tract. Potassium chloride is essential for the healthy functioning of organs. Sodium bicarbonate works by neutralising high levels of acid in the stomach, helping to treat acidity and heartburn. Sodium chloride maintains sodium levels in the body. Together, Pegclear Oral Solution helps in a comfortable bowel movement and provides relief from constipation.

How Pegclear Oral Solution Works

Pegclear Oral Solution is a combination of four drugs, namely Polyethylene glycol, Potassium chloride, Sodium bicarbonate, and Sodium chloride. Polyethylene glycol draws water into the intestine and softens stools, making them easier to pass. Potassium chloride is essential for the healthy functioning of organs. Sodium bicarbonate works by neutralising high levels of acid in the stomach, helping to treat acidity and heartburn. Sodium chloride maintains sodium levels in the body. Together, Pegclear Oral Solution helps in relieving constipation.

Storage

Keep Pegclear Oral Solution out of reach and sight of children.
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Side effects of Pegclear Oral Solution 200 ml
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
Here are the few steps for dealing with itching caused by drug use:
  • Report the itching to your doctor immediately; they may need to change your medication or dosage.
  • Use a cool, damp cloth on the itchy area to help soothe and calm the skin, reducing itching and inflammation.
  • Keep your skin hydrated and healthy with gentle, fragrance-free moisturizers.
  • Try not to scratch, as this can worsen the itching and irritate your skin.
  • If your doctor prescribes, you can take oral medications or apply topical creams or ointments to help relieve itching.
  • Track your itching symptoms and follow your doctor's guidance to adjust your treatment plan if needed. If the itching persists, consult your doctor for further advice.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.

What if I have taken an overdose of Pegclear Oral Solution

Take Pegclear Oral Solution only as advised by the physician. Do not exceed the recommended dose, as it might cause an overdose. If you suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

If you are allergic to Pegclear Oral Solution or any other medicines, please tell your doctor. If you have ulcerative colitis or Crohn’s disease, inform your doctor before taking Pegclear Oral Solution . Pegclear Oral Solution is not recommended for children below 12 years of age. If you are pregnant or breastfeeding, please consult a doctor before taking Pegclear Oral Solution . Drink plenty of fluids while taking Pegclear Oral Solution . Do not take Pegclear Oral Solution in more than the recommended doses. Discard Pegclear Oral Solution after 30 days of first opening the bottle. Do not freeze or refrigerate Pegclear Oral Solution .

Drug-Drug Interactions

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Critical

Drug-Drug Interactions

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Critical
How does the drug interact with Pegclear Oral Solution 200 ml:
Taking Mepenzolate and Pegclear Oral Solution 200 ml(in tablet or capsule form) together can increase the risk of stomach ulcers, bleeding, and other gastrointestinal injury.

How to manage the interaction:
Taking Mepenzolate with Pegclear Oral Solution 200 ml is not recommended, as it can lead to an interaction, it can be taken if a doctor has prescribed it. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, dark, tarry stools, consult the doctor immediately.
How does the drug interact with Pegclear Oral Solution 200 ml:
Taking Olanzapine with Pegclear Oral Solution 200 ml can increase the risk of stomach ulcers, bleeding, and gastrointestinal injury.

How to manage the interaction:
Co-administration of Olanzapine and Pegclear Oral Solution 200 ml is not recommended as it leads to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like severe abdominal pain, bloating, sudden dizziness or lightheadedness, nausea, vomiting (especially with blood), loss of appetite, and/or black, tarry stools, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Critical
How does the drug interact with Pegclear Oral Solution 200 ml:
Taking Biperiden with Pegclear Oral Solution 200 ml can increase the risk of stomach ulcers.

How to manage the interaction:
Taking Biperiden with Pegclear Oral Solution 200 ml is not recommended as it can lead to an interaction, but can be taken if prescribed by the doctor. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, or dark, tarry stools, consult the doctor immediately. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Pegclear Oral Solution 200 ml:
Coadministration of Oxybutynin with Pegclear Oral Solution 200 ml can increase the risk of developing stomach ulcers.

How to manage the interaction:
Taking Oxybutynin with Pegclear Oral Solution 200 ml is generally avoided as it can lead to an interaction, it can be taken when a doctor has prescribed it. Consult the doctor immediately if you experience severe stomach pain, bloating, lightheadedness, dizziness, vomiting (especially with blood), decreased hunger, or dark stools. Do not discontinue any medication without contacting a doctor.
How does the drug interact with Pegclear Oral Solution 200 ml:
Taking Promethazine with Pegclear Oral Solution 200 ml can increase the risk of stomach ulcers.

How to manage the interaction:
Taking Promethazine with Pegclear Oral Solution 200 ml is not recommended, as it can lead to an interaction, they can be taken if a doctor has prescribed it. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, dark, tarry stools, consult the doctor immediately.
How does the drug interact with Pegclear Oral Solution 200 ml:
Co-administration of Dimenhydrinate and Pegclear Oral Solution 200 ml can increase the risk of stomach inflammation.

How to manage the interaction:
Co-administration of Dimenhydrinate with Pegclear Oral Solution 200 ml is generally not recommended, as it can lead to an interaction, it can be taken when a doctor has prescribed it. However, if you experience severe stomach pain, sudden dizziness, vomiting (especially with blood), or dark stools, consult the doctor immediately. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Pegclear Oral Solution 200 ml:
Taking Dexchlorpheniramine and Pegclear Oral Solution 200 ml can increase the risk of stomach inflammation.

How to manage the interaction:
Taking Dexchlorpheniramine with Pegclear Oral Solution 200 ml (in tablet or capsule form) is avoided as it can lead to an interaction, it can be taken if a doctor has prescribed it. However, if you experience severe stomach pain, bloating, lightheadedness, vomiting, or dark stools, consult the doctor immediately. Do not stop using any medications without talking to a doctor.
Potassium chlorideOrphenadrine (chloride)
Critical
How does the drug interact with Pegclear Oral Solution 200 ml:
Taking Orphenadrine and Pegclear Oral Solution 200 ml (in tablet or capsule form) together can increase the risk of stomach ulcers, bleeding, and other gastrointestinal injury.

How to manage the interaction:
Taking Orphenadrine (chloride) with Pegclear Oral Solution 200 ml is not recommended, as it can lead to an interaction, it can be taken if a doctor has prescribed it. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, dark, tarry stools, consult the doctor immediately.
Critical
How does the drug interact with Pegclear Oral Solution 200 ml:
Taking Difenoxin and Pegclear Oral Solution 200 ml (in tablet or capsule form) together can increase the risk of stomach ulcers, bleeding, and other gastrointestinal injury.

How to manage the interaction:
Taking Difenoxin with Pegclear Oral Solution 200 ml is not recommended, as it can lead to an interaction, it can be taken if a doctor has prescribed it. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, dark, tarry stools, consult the doctor immediately.
Potassium chlorideOrphenadrine (citrate)
Critical
How does the drug interact with Pegclear Oral Solution 200 ml:
Combining Orphenadrine with Pegclear Oral Solution 200 ml can increase the risk of stomach ulcers.

How to manage the interaction:
Taking Orphenadrine (citrate) with Pegclear Oral Solution 200 ml is not recommended, as it can lead to an interaction, can be taken if your doctor has prescribed it. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, dark, tarry stools, consult the doctor immediately.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Try maintaining a balanced diet, which includes fresh fruits and vegetables.
  • Stay hydrated by drinking enough water and fluids.
  • Exercise regularly, and stay fit.
  • Get enough sleep.
  • Eat food rich in fibre, such as whole-wheat bread, oatmeal, flaxseed, nuts, beans, lentils, fruits (berries, apples, oranges, bananas, pears, figs), and vegetables (broccoli, spinach, sweet potatoes, avocados).

Habit Forming

No

Therapeutic Class

LAXATIVES
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Alcohol

Consult your doctor

The interaction of alcohol with Pegclear Oral Solution is unknown. Please consult a doctor before consuming alcohol while using Pegclear Oral Solution .

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Pregnancy

Caution

Please consult a doctor if you are pregnant. Pegclear Oral Solution is given to pregnant women only if the doctor thinks the benefits outweigh the risks.

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Breast Feeding

Caution

Please consult a doctor if you are breastfeeding. Pegclear Oral Solution is given to breastfeeding mothers only if the doctor thinks the benefits outweigh the risks.

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Driving

Safe

Pegclear Oral Solution usually does not affect your ability to drive or operate machinery.

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Liver

Caution

Take Pegclear Oral Solution with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Pegclear Oral Solution with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Caution

Pegclear Oral Solution is not recommended for children under 12 years of age, as its safety and effectiveness have not been established.

Have a query?

FAQs

Pegclear Oral Solution belongs to a class of drugs called laxatives, used to treat constipation.

Pegclear Oral Solution contains Polyethylene glycol, Potassium chloride, Sodium bicarbonate and Sodium chloride. Polyethylene glycol draws water into the intestine and softens stools, making it easier to pass. Potassium chloride is essential for the healthy functioning of organs. Sodium bicarbonate works by neutralising high levels of acid in the stomach, helping to treat acidity and heartburn. Sodium chloride maintains sodium levels in the body. Together, Pegclear Oral Solution helps in relieving constipation.

Pegclear Oral Solution may cause mild diarrhoea as a side effect at the beginning of the treatment. It usually gets better by reducing the amount of Pegclear Oral Solution intake. However, if the condition persists or worsens, please consult a doctor.

You are not recommended to take Pegclear Oral Solution with anticonvulsants as it may reduce the effectiveness of anticonvulsants (medicines for epilepsy). However, please consult your doctor before taking Pegclear Oral Solution with other medicines.

You are recommended to avoid foods that are high in fat and low in fibre, such as ice cream, red meat, frozen meals, potato chips, cheese, hot dogs and hamburgers.

You are not recommended to take more than the advised dose of Pegclear Oral Solution as it may cause excessive diarrhoea that might lead to dehydration. If you have diarrhoea, stop taking Pegclear Oral Solution and drink plenty of fluids to avoid dehydration. However, if the condition persists or worsens, please consult a doctor.

Country of origin

India

Manufacturer/Marketer address

Office No. 5119, 5th Floor, 'D' Wing, Oberoi Garden Estates, Chandivili, Andheri (E), Mumbai - 400 072.
Other Info - PEG0065

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