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Pegrest Sugar Free Oral Solution is used to treat constipation. It works by drawing water into the intestine, which softens the stools, making them easier to pass. In some cases, this medicine may cause side effects such as stomach pain, indigestion, mild diarrhoea, nausea, or vomiting. Before taking this medicine, inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

About Pegrest Sugar Free Oral Solution

Pegrest Sugar Free Oral Solution is a medicine used to treat ongoing constipation and to clear the digestive tract completely before medical tests or surgeries. It works by bringing water into your bowel, which softens your stool and makes bowel movements more frequent and easier to pass. This helps ensure your intestines are completely clear for diagnostic procedures like colonoscopies.

To get the best results, you must take the Pegrest Sugar Free Oral Solution exactly as directed by your doctor. If you are taking it for daily constipation, consistency is key, and you should take it at the same time each day, with or without food. Along with taking this medicine, drinking plenty of water, eating fiber-rich foods, and staying physically active can significantly improve your digestive health.

While taking Pegrest Sugar Free Oral Solution , some people may experience mild stomach discomfort, bloating, or nausea. These symptoms are usually temporary, but if you experience severe vomiting, severe abdominal pain, or blood in your stool, you should contact your doctor immediately.

Do not take this if you have a bowel obstruction, a tear in your stomach or intestinal wall, or severe inflammatory bowel conditions. Always talk to your doctor before starting Pegrest Sugar Free Oral Solution if you have kidney problems, heart conditions, or a history of salt imbalances in your blood.

Because Pegrest Sugar Free Oral Solution works by flushing your bowel, it can prevent other oral medicines from being absorbed properly if taken at the same time. Talk to your doctor or pharmacist if you take blood pressure medications, or if you are pregnant, breastfeeding, or elderly, to ensure you can use this medicine safely.

Uses of Pegrest Sugar Free Oral Solution

Pegrest Sugar Free Oral Solution is used to relieve constipation and cleanse the bowel before certain medical procedures. The detailed uses are as follows:

  • Chronic constipation: Pegrest Sugar Free Oral Solution helps by drawing water into the bowel to soften dry, hard stool, making it much easier to pass.
  • Bowel cleansing before medical procedures: Pegrest Sugar Free Oral Solution clears out the digestive tract completely so that doctors can get a clear view during examinations like colonoscopies or X-rays.

Key Benefits

Pegrest Sugar Free Oral Solution helps relieve constipation, promote comfortable bowel movements, and support effective bowel cleansing. The key benefits include:

  • Relieves constipation: Softens stools and makes bowel movements easier to pass.
  • Promotes comfortable bowel movements: Helps reduce straining and discomfort during defecation.
  • Supports bowel cleansing: Effectively clears the bowel before medical procedures such as colonoscopy.
  • Helps maintain hydration: The added electrolytes help reduce the risk of dehydration during bowel preparation.
  • Supports effective diagnosis: A well-cleansed bowel allows better visualisation during diagnostic procedures.
  • Improves digestive comfort: Helps relieve the discomfort associated with chronic constipation.

Directions for Use

  • Pegrest Sugar Free Oral Solution can be taken with or without food, or as advised by your doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Check the label for directions. Dilute Pegrest Sugar Free Oral Solution with water as advised by your doctor. Take it orally using the measuring cup provided with the package.
  • Shake the bottle well before each use.

How Pegrest Sugar Free Oral Solution Works

Pegrest Sugar Free Oral Solution contains polyethylene glycol, potassium chloride, sodium bicarbonate, and sodium chloride, which work together to relieve constipation and cleanse the bowel while maintaining the body's fluid and electrolyte balance. Polyethylene glycol is an osmotic agent that binds to water and carries it into the colon, where it softens hard stools, increases stool volume, and stimulates natural bowel movements. Potassium chloride, sodium bicarbonate, and sodium chloride replace essential electrolytes that may be lost during bowel cleansing, helping maintain hydration and normal electrolyte levels. Together, these ingredients provide effective bowel cleansing while reducing the risk of dehydration and electrolyte imbalance.
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Alcohol

Consult your doctor

The interaction of alcohol with Pegrest Sugar Free Oral Solution is unknown. Please consult a doctor before consuming alcohol while using Pegrest Sugar Free Oral Solution .

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Pregnancy

Caution

Please consult a doctor if you are pregnant. Pegrest Sugar Free Oral Solution is given to pregnant women only if the doctor thinks the benefits outweigh the risks.

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Breast Feeding

Caution

Please consult a doctor if you are breastfeeding. Pegrest Sugar Free Oral Solution is given to breastfeeding mothers only if the doctor thinks the benefits outweigh the risks.

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Driving

Safe

Pegrest Sugar Free Oral Solution usually does not affect your ability to drive or operate machinery.

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Liver

Caution

Take Pegrest Sugar Free Oral Solution with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Pegrest Sugar Free Oral Solution with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Caution

Pegrest Sugar Free Oral Solution is not recommended for children under 12 years of age, as its safety and effectiveness have not been established.

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Heart

Caution

Pegrest Sugar Free Oral Solution should be used with caution in patients with heart problems. Inform your doctor about any heart-related conditions before taking Pegrest Sugar Free Oral Solution .

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Geriatrics

Caution

Pegrest Sugar Free Oral Solution should be given with caution in elderly patients due to an increased risk of side effects. Seek medical advice before using Pegrest Sugar Free Oral Solution .

What if I have taken an overdose of Pegrest Sugar Free Oral Solution

If you take more than the recommended dose of Pegrest Sugar Free Oral Solution , seek immediate medical attention. Symptoms of an overdose may include severe diarrhoea, dehydration, or electrolyte imbalance.

Diet & Lifestyle Advise

  • Stay well hydrated: Drink plenty of clear fluids, such as water, clear broths, or herbal teas, especially when using Pegrest Sugar Free Oral Solution for bowel preparation.
  • Increase dietary fibre: If treating constipation, gradually include more fruits, vegetables, and whole grains in your diet to support regular bowel movements.
  • Stay physically active: Engage in light exercise, such as daily walking, to help stimulate natural bowel function.
  • Avoid gas-producing foods and drinks: Limit carbonated beverages and foods that commonly cause bloating or excess gas.
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How Soon It Starts Working

The time required for Pegrest Sugar Free Oral Solution to start to work: The time required for Pegrest Sugar Free Oral Solution to show its action is unknown.

The time for which the effects of Pegrest Sugar Free Oral Solution last: The duration of action for Pegrest Sugar Free Oral Solution is clinically unknown.

Storage

•Store the unmixed powder at 15°C to 30°C in a cool, dry place away from heat, direct light, and moisture. Do not store it in the bathroom.

What if you forget to take Pegrest Sugar Free Oral Solution

If you are taking Pegrest Sugar Free Oral Solution daily for constipation and miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed one and continue with your regular schedule. Do not take a double dose to make up for a missed one. If you are preparing for a medical procedure and miss a dose or fall behind on your drinking schedule, contact your doctor or the clinic immediately for guidance.

Drug Warnings

  • Check the prepared solution: Drink the solution only if it is clear and free of undissolved powder. Do not use it if it appears cloudy or discoloured.
  • Do not alter the solution: Do not add sugar, flavourings, or thickeners, as they may affect how Pegrest Sugar Free Oral Solution works.
  • Chill before use: Refrigerating the prepared solution may improve its taste. Do not freeze it.
  • Manage bloating: If you develop severe abdominal bloating or distension, slow down or temporarily stop drinking the solution until the symptoms improve.
  • Special dietary restrictions: Consult your doctor before using Pegrest Sugar Free Oral Solution if you are on a sodium-restricted or potassium-restricted diet.

verifiedApollotooltip

The following medicines may interact with Pegrest Sugar Free Oral Solution and may require closer monitoring:

  • Oral medicines: Taking other oral medicines within 1 hour of Pegrest Sugar Free Oral Solution may reduce their absorption and effectiveness.
  • Diuretics (water tablets) and blood pressure medicines: Taking these with Pegrest Sugar Free Oral Solution may increase the risk of dehydration or electrolyte imbalance. Your doctor may recommend closer monitoring.

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verifiedApollotooltip
  • Starch-based food thickeners: Do not mix Pegrest Sugar Free Oral Solution with starch-based thickeners, as it can reduce the effectiveness of both products.

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Habit Forming

No

Therapeutic Class

[LAXATIVES]

FAQs

Pegrest Sugar Free Oral Solution belongs to a class of drugs called laxatives, used to treat constipation.
Pegrest Sugar Free Oral Solution contains Polyethylene glycol, Potassium chloride, Sodium bicarbonate and Sodium chloride. Polyethylene glycol draws water into the intestine and softens stools, making it easier to pass. Potassium chloride is essential for the healthy functioning of organs. Sodium bicarbonate works by neutralising high levels of acid in the stomach, helping to treat acidity and heartburn. Sodium chloride maintains sodium levels in the body. Together, Pegrest Sugar Free Oral Solution helps in relieving constipation.
Pegrest Sugar Free Oral Solution may cause mild diarrhoea as a side effect at the beginning of the treatment. It usually gets better by reducing the amount of Pegrest Sugar Free Oral Solution intake. However, if the condition persists or worsens, please consult a doctor.
You are not recommended to take Pegrest Sugar Free Oral Solution with anticonvulsants as it may reduce the effectiveness of anticonvulsants (medicines for epilepsy). However, please consult your doctor before taking Pegrest Sugar Free Oral Solution with other medicines.
You are recommended to avoid foods that are high in fat and low in fibre, such as ice cream, red meat, frozen meals, potato chips, cheese, hot dogs and hamburgers.
You are not recommended to take more than the advised dose of Pegrest Sugar Free Oral Solution as it may cause excessive diarrhoea that might lead to dehydration. If you have diarrhoea, stop taking Pegrest Sugar Free Oral Solution and drink plenty of fluids to avoid dehydration. However, if the condition persists or worsens, please consult a doctor.
It is best to dissolve the powder only in water as directed on the package. Mixing it with juice, soda, or other drinks can alter the concentration of salts and affect how the medicine works. Talk to your doctor or pharmacist before adding anything to the solution.
If you are taking Pegrest Sugar Free Oral Solution to cleanse your bowel before a medical procedure, you must avoid solid foods and only consume clear liquids. If you are taking it for daily constipation, you can eat normally. Talk to your doctor for specific dietary guidelines.
Since Pegrest Sugar Free Oral Solution is minimally absorbed by the body, it is generally considered safe, but you should always talk to your doctor before taking any laxative during pregnancy or breastfeeding.
If you feel nauseous, try drinking the solution more slowly or take a brief break of 15 to 30 minutes before resuming. Drinking the solution chilled can also help reduce nausea. Talk to your doctor if the nausea is severe or if you vomit.
Mild stomach cramps and bloating are common side effects as the medicine works to move stool through your bowels. However, if you experience severe, sharp, or persistent stomach pain, stop taking the medicine and contact your doctor immediately.
Pegrest Sugar Free Oral Solution can prevent other oral medicines from being absorbed properly because it speeds up bowel movements. You should take your other oral medications at least 1 hour before or 1 hour after taking Pegrest Sugar Free Oral Solution . Talk to your doctor or pharmacist to plan your medication schedule safely.
Your bowel preparation is typically complete when your bowel movements become clear, yellowish, and free of solid matter. If your stool is still dark or contains solid particles near the time of your procedure, contact your doctor's clinic for advice.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

38, VENKATESHWARA NG, OLD SAFILGUDA SECUNDERABAD Hyderabad TG 500047 IN
Other Info - PEG0133
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