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Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Problast Capsule is used to treat low blood calcium levels. It increases calcium levels and provides essential nutrients that help maintain bone health. In some cases, this medicine may cause side effects such as constipation or stomach upset, nausea, vomiting, loss of appetite, and headache. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Manufacturer/Marketer :

Goddres Pharmaceuticals Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Problast Capsule

Problast Capsule is used to treat low blood calcium levels. It effectively treats various conditions caused by low calcium levels in the body, such as osteoporosis (weak and brittle bones), osteomalacia/rickets (weak bones), hypoparathyroidism (low levels of parathyroid hormone), and latent tetany (a muscle disease with low blood calcium levels).

Problast Capsule can also be given to pregnant, nursing, and postmenopausal women to ensure that they are getting enough calcium. Additionally, Problast Capsule is used to treat hyperparathyroidism (overactive parathyroid glands) and metabolic bone disease in people with chronic kidney disease, surgery, or other conditions.

Problast Capsule consists of three medicines: Calcium carbonate (mineral), Calcitriol (Vitamin D3), and  Zinc (mineral). Calcium provides essential nutrients for bone formation and maintenance. Calcitriol helps in improving the absorption of calcium from the intestine. Zinc stimulates osteoblastic bone formation and mineralisation.

In some cases, Problast Capsule can cause side effects like constipation or stomach upset, nausea, vomiting, loss of appetite, mood changes, weakness, tiredness, fast or pounding heartbeat, bone/muscle pain, and headache. Most of these side effects do not require medical attention and gradually resolve over time. However, if these side effects persist longer, please consult your doctor.

If you are known to be allergic to any of the components in Problast Capsule , please inform your doctor. Pregnant or breastfeeding women should consult their doctor before taking Problast Capsule . Let your doctor know if you are taking any other medicines or have pre-existing medical conditions to prevent potential interactions.

Uses of Problast Capsule

Problast Capsule is indicated for the prevention and treatment of various conditions caused by calcium and vitamin D deficiency. The detailed uses of Problast Capsule are as follows:

  • Treatment of Osteoporosis: Helps strengthen bones and reduce the risk of fractures in people with brittle or porous bones.
  • Management of Osteomalacia (Rickets): Treats softening of the bones caused by vitamin D deficiency, especially in children (rickets) and adults (osteomalacia).
  • Correction of Vitamin D Deficiency: Corrects low levels of vitamin D in the body, which is essential for calcium absorption and bone health.
  • Treats Hypoparathyroidism: Manages calcium levels in patients with underactive parathyroid glands by improving calcium absorption.
  • Manages Latent Tetany: Prevents and treats muscle cramps and spasms caused by low calcium levels in the blood.

Directions for Use

  • Problast Capsule can be taken with or without food as advised by your doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
  • Swallow Problast Capsule as a whole with a glass of water.
  • Do not chew, crush or break it.

Medicinal Benefits

  • Problast Capsule is a nutritional supplement composed of Calcium Carbonate, Calcitriol (Vitamin D3), and Zinc, used to correct calcium and vitamin D deficiencies and support bone health.
  • It replenishes low calcium levels in the body, supporting the proper functioning of nerves, muscles, and bones.
  • Problast Capsule is indicated for the treatment of osteoporosis, osteomalacia, and rickets, by strengthening bones and preventing fractures or deformities.
  • It enhances calcium absorption from the intestine and maintains adequate blood calcium levels, especially in patients with hypoparathyroidism or chronic kidney disease.
  • Problast Capsule helps in the treatment of tetany, a condition characterised by painful muscle cramps and spasms due to low calcium levels.
  • It plays a vital role in bone regeneration, collagen formation, and protein synthesis, all of which are crucial for maintaining bone density and structure.

How Problast Capsule Works

Problast Capsule consists of three medicines: Calcium carbonate (mineral), Calcitriol (Vitamin D3), and Zinc (mineral). Calcium is a mineral that is used to prevent or treat a calcium deficiency. It provides essential nutrients for bone formation and maintenance. Calcitriol is a synthetic version of Vitamin D3. It raises Vitamin D levels and thereby increases calcium levels in the blood. This helps in improving the absorption rate of calcium from the intestine. Zinc is a mineral that plays an essential role in bone health. Zinc helps to stimulate osteoblastic bone formation and mineralisation.

Storage

• Store in a cool and dry place away from sunlight.• Keep Problast Capsule out of the sight and reach of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
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What if I have taken an overdose of Problast Capsule

Take Problast Capsule only as suggested by the physician. Do not exceed the recommended dose, as it might cause an overdose. If you suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

  • If you are known to be allergic to Problast Capsule or any other medicines, please tell your doctor.
  • Problast Capsule is not recommended if you have hypercalcemia (high calcium levels), metastatic calcification (extra deposits of calcium in the body), hypervitaminosis D (high vitamin D levels), and malabsorption syndrome (difficulty absorbing nutrition from food).
  • Inform your doctor before taking Problast Capsule if you have any heart/kidney/liver/blood vessel diseases, kidney stones, sarcoidosis (growth of inflammatory cells in different parts of the body), Crohn's disease (inflammatory bowel disease), Whipple's disease (bacterial infection affecting joints and digestive system), achlorhydria (little or no stomach acid), low levels of bile, or phosphate imbalance.
  • If you are pregnant, planning to become pregnant, or breastfeeding, it is advised to inform your doctor before using Problast Capsule .
  • Problast Capsule should be used with caution in children and only if recommended by a doctor.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Problast Capsule:
Coadministration of Problast Capsule with Eltrombopag can impair the absorption of Eltrombopag which leads to increased levels in the blood. This can increase the risk and severity of side effects.

How to manage the interaction:
Taking Problast Capsule with Eltrombopag together is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any body aches or pain, chills, cough, difficulty in breathing, fever, headache, or loss of voice you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Problast Capsule:
Taking dolutegravir with Problast Capsule can reduce the effectiveness of dolutegravir.

How to manage the interaction:
Taking Problast Capsule with Dolutegravir together can result in an interaction, it can be taken if your doctor has advised it. However, take dolutegravir at least two hours before or six hours after the Problast Capsule dose. Do not stop using any medications without talking to a doctor.
How does the drug interact with Problast Capsule:
Coadministration of Problast Capsule with Gefitinib impairs absorption and increases the Gefitinib levels in the body. This may increase the risk or severity of side effects.

How to manage the interaction:
Taking Problast Capsule with Gefitinib together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any Blistering, peeling or loosening of the skin, bloody, black, or tarry stools, eye redness or pain, heartburn, indigestion, joint or muscle pain, or abdomen pain you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
CalcitriolBurosumab
Severe
How does the drug interact with Problast Capsule:
Co-administration of Problast Capsule and Burosumab may cause increases in phosphorus and vitamin D levels in the blood, which may lead to an increased risk of kidney stones.

How to manage the interaction:
There may be a possibility of interaction between Problast Capsule and Burosumab, but it can be taken if prescribed by a doctor. If you have any of these symptoms like kidney stones, it's important to contact a doctor right away. Do not stop using any medications without a doctor's advice. Do not discontinue the medication without consulting a doctor.
CalcitriolDigitoxin
Severe
How does the drug interact with Problast Capsule:
Co-administration of Problast Capsule with Digitoxin may increase the risk or severity of digitoxin toxicity and irregular heart rhythm.

How to manage the interaction:
Although there is an interaction, Problast Capsule can be taken with Digitoxin if prescribed by the doctor. Consult the prescriber if you experience symptoms that could indicate high blood calcium, such as weakness, fatigue, headache, dizziness, drowsiness, ringing in the ears, loss of appetite, nausea, vomiting, constipation, dry mouth, a metallic taste in the mouth, bone or muscle pain, incoordination, frequent urination, and weight loss. Also, seek medical attention if you experience symptoms of digitoxin toxicity, such as blurred vision, slow pulse, or irregular heartbeats. Do not discontinue the medication without consulting a doctor.
CalcitriolParicalcitol
Severe
How does the drug interact with Problast Capsule:
Co-administration of Paricalcitol and Problast Capsule are forms of vitamin D, and taking too much vitamin D may lead to toxic effects related to excessive calcium levels in the blood and urine.

How to manage the interaction:
Concomitant use of Paricalcitol with Problast Capsule can lead to an interaction, it can be taken if advised by a doctor. Consult the prescriber if you experience symptoms of vitamin D intoxication such as weakness, fatigue, headache, vertigo, drowsiness, ringing in the ears, loss of appetite, nausea, vomiting, constipation, dry mouth, metallic taste, muscle pain, bone pain, muscle incoordination, and low muscle tone. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Problast Capsule:
Co-administration of Orlistat with Problast Capsule may reduce the levels of Problast Capsule which can lead to low treatment outcomes.

How to manage the interaction:
Although there is an interaction, Problast Capsule can be taken with Orlistat when prescribed by the doctor. Do not discontinue any medications without consulting a doctor.
CalcitriolMetolazone
Severe
How does the drug interact with Problast Capsule:
Co-administration of Metolazone with Problast Capsule can cause blood calcium levels to become too high.

How to manage the interaction:
Although there is an interaction, Problast Capsule can be taken with metolazone if prescribed by the doctor. Consult the doctor if you experience symptoms such as dizziness, drowsiness, weakness, lethargy, headache, nausea, vomiting, or seizures. Do not discontinue the medication without consulting a doctor.
CalcitriolDihydrotachysterol
Severe
How does the drug interact with Problast Capsule:
Co-administration of Problast Capsule with Dihydrotachysterol can increase the risk of adverse effects.

How to manage the interaction:
Co-administration of Dihydrotachysterol with Problast Capsule can possibly result in an interaction, but it can be taken if your doctor has advised it. If you notice any of these symptoms - irregular heartbeat, seizures, weakness, tiredness, headache, dizziness, ringing in the ears, loss of appetite, feeling sick, throwing up, constipation, dry mouth, strange taste in your mouth, muscle or bone pain, trouble coordinating movements, weak muscles, peeing a lot, feeling very thirsty, losing weight, eye infection, sensitivity to light, itching, or a higher body temperature - make sure to call a doctor right away. Do not discontinue any medications without consulting a doctor.
CalcitriolFosphenytoin
Severe
How does the drug interact with Problast Capsule:
Taking Problast Capsule with Fosphenytoin can reduce the levels and efficacy of Problast Capsule.

How to manage the interaction:
Taking Problast Capsule with Fosphenytoin together can possibly result in an interaction, but it can be taken if a doctor has advised it. If you notice any symptoms of sudden dizziness, weakness, chest pain or pressure, abnormal body movements, uncontrollable eye movements, itching, burning, or tingling sensation, it's important to contact a doctor right away. Do not stop using any medications without a doctor's advice. Do not discontinue the medication without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Include dairy products like milk, yoghurt, cheese, or milk-based custard in your diet.
  • Eat daily a serving of broccoli, cabbage, bok choy, spinach, and other green leafy vegetables.
  • Snack on calcium-rich nuts like Brazil nuts or almonds.
  • Sprinkle sesame seeds over your food, vegetables, and salads. Sesame seeds are high in calcium.
  • Avoid or reduce the intake of caffeine, soft drinks, and alcohol, as they may inhibit calcium absorption.
  • Replace the meat with tofu or tempeh for extra calcium in your food.

Habit Forming

No

Therapeutic Class

MULTIMINERALS
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Alcohol

Caution

Drinking alcohol can affect calcium absorption; hence, it is advised to limit alcohol intake while using Problast Capsule .

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Pregnancy

Caution

Consult your doctor if you are pregnant. Your doctor will weigh the potential risks and benefits before recommending Problast Capsule .

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Breast Feeding

Caution

Problast Capsule can pass into the breast milk. Consult your doctor before taking Problast Capsule if you are breastfeeding.

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Driving

Safe

No interaction was found/established.

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Liver

Caution

Let your doctor know if you have any history of liver disease before taking Problast Capsule . Hepatic impairment/liver disease can alter the metabolic and therapeutic activity of certain Vitamin D forms.

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Kidney

Caution

Seek a doctor's advice before starting Problast Capsule if you have kidney diseases like kidney stones or are undergoing dialysis. Calcitriol in Problast Capsule increases inorganic phosphate levels in serum; hence, caution should be taken in patients undergoing dialysis to maintain adequate phosphorus levels and avoid ectopic calcification (calcium deposition).

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Children

Caution

Problast Capsule should be used with caution in children and only if recommended by a doctor.

Have a query?

FAQs

Problast Capsule is used to treat Osteoporosis, Postmenopausal osteoporosis, Osteomalacia, Rickets, Calcium deficiency and Tetany.

Problast Capsule is a combination of three medicines, namely: Calcium carbonate, Calcitriol and Zinc. Calcitriol helps your body effectively absorb Calcium Carbonate and additionally supports the muscles needed to avoid falls. Calcium and Zinc help build and maintain bones. Collectively, Problast Capsule treats osteoporosis (weak and brittle bones), osteomalacia/rickets (weak bones), hypoparathyroidism (low levels of parathyroid hormone), and tetany (a muscle disease with low blood calcium levels).

Problast Capsule is used to increase low levels of calcium in the body. Hence, it is not advised to use Problast Capsule during hypercalcemia, since it causes the overdose of calcium, leading to kidney stones and other effects.

Problast Capsule can cause kidney stones due to excess calcium deposition when used for a prolonged period. Please consult your doctor before taking Problast Capsule as a daily supplement if you have any kidney problems or a history of kidney stones.

Common side effects of Problast Capsule include constipation, stomach pain, loss of appetite, fast or pounding heartbeat, bone, or muscle pain.

Do not use Problast Capsule if you are allergic to Problast Capsule or any other ingredients in it. Problast Capsule is not recommended in hypercalcemia (high calcium levels), metastatic calcification (extra deposits of calcium in the body), hypervitaminosis D (high vitamin D levels), and malabsorption syndrome (difficulty absorbing nutrition from food).

Problast Capsule can be taken either before or after eating. If stomach upset occurs, taking it with food may help alleviate discomfort. Always follow your doctor's personalised instructions.

Country of origin

INDIA

Manufacturer/Marketer address

Godrej One, 4th Floor, Pirojshanagar, Eastern Express Highway, Vikhroli(East), Mumbai 400079, India
Other Info - PRO1019

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