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  3. Sodium Bicarbonate - 450G

Sodium Bicarbonate - 450G, Pack of 1 POWDER
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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Sodium Bicarbonate - 450G is used to treat acid indigestion, heartburn, sour stomach, and stomach upset. It may also be prescribed to make the blood or urine less acidic in certain conditions. It contains Sodium bicarbonate, which helps neutralise the acidic pH in the stomach. In some cases, it may cause side effects such as dry mouth, urinating more than usual, and increased thirst. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Composition :

SODIUM BICARBONATE-7.50%W/V

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Sodium Bicarbonate - 450G

Sodium Bicarbonate - 450G is mainly used to treat acid indigestion, heartburn, sour stomach, and stomach upset. Sodium Bicarbonate - 450G may also be prescribed to make the blood or urine less acidic in certain conditions. It helps correct the acid-alkaline balance in the body.

Sodium Bicarbonate - 450G contains sodium bicarbonate, which helps neutralize the stomach's acidic pH. Thereby, Sodium Bicarbonate - 450G helps to provide relief from acidity.

Sometimes, you may experience common side effects such as dry mouth, urinating more than usual, and increased thirst. Most of these side effects do not require medical attention and will resolve gradually. However, talk to your doctor if the side effects persist or worsen.

Inform your doctor if you have any conditions like high blood pressure, kidney, liver or heart disease, or have recently had bleeding in the stomach. Consult your doctor if you are pregnant, planning for pregnancy or breastfeeding.

Uses of Sodium Bicarbonate - 450G

Sodium Bicarbonate - 450G is used in the treatment of heartburn, indigestion, stomach upset, and sour stomach. The detailed uses of Sodium Bicarbonate - 450G are as follows:

  • Heartburn: Sodium Bicarbonate - 450G treats heartburn by neutralizing stomach acid and providing quick relief from burning sensations in the chest and throat.
  • Indigestion: Sodium Bicarbonate - 450G relieves indigestion by balancing stomach pH and alleviating discomfort caused by excess acid.
  • Stomach Upset: Sodium Bicarbonate - 450G reduces stomach upset and conditions like sour stomach and acidity by reducing acidity, soothing the stomach lining, and restoring a balanced digestive environment.

Directions for Use

  • Sodium Bicarbonate - 450G can be taken with or without food.
  • It is usually taken one to four times a day or as recommended by your doctor.
  • Dissolve Sodium Bicarbonate - 450G in a glass of water and consume it immediately.
  • Do not store the mixture for later use.
  • Avoid touching the granules with wet or unclean hands to prevent contamination.

Medicinal Benefits

  • Sodium Bicarbonate - 450G belongs to a group of medicines called alkalinising agents used to correct the acid-alkaline balance in the body.
  • Sodium Bicarbonate - 450G is used to treat acid indigestion, heartburn, sour stomach, and stomach upset.
  • Sodium Bicarbonate - 450G can also be prescribed to make the blood or urine less acidic in certain conditions.
  • Sodium Bicarbonate - 450G helps neutralise the acidic pH in the stomach. Thereby, Sodium Bicarbonate - 450G helps to provide relief from acidity.

How Sodium Bicarbonate - 450G Works

Sodium Bicarbonate - 450G contains sodium bicarbonate, which helps neutralise the stomach's acidic pH. Thereby, Sodium Bicarbonate - 450G helps to provide relief from acidity.

Storage

• Store in a cool and dry place away from sunlight.• Keep Sodium Bicarbonate - 450G out of reach and sight of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if I have taken an overdose of Sodium Bicarbonate - 450G

Take Sodium Bicarbonate - 450G only as prescribed by the physician. Avoid exceeding the recommended dose as it could lead to an overdose. Symptoms of overdose may include muscle spasms and seizures. If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

  • Do not take Sodium Bicarbonate - 450G if you are allergic to any of its components.
  • Inform your doctor if you have blood abnormalities, kidney stones, high blood pressure, kidney failure, heart failure, fluid retention, or if your breathing is slower than usual.
  • Consult your doctor if you are pregnant, planning for pregnancy or breastfeeding.
  • Sodium Bicarbonate - 450G should not be given to children unless prescribed by the doctor.
  • Avoid consuming alcohol, as it can lead to increased production of stomach acid, thereby increasing acidity and heartburn.

Drug-Drug Interactions

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Sodium bicarbonateDolutegravir
Severe
Sodium bicarbonateGefitinib
Severe

Drug-Drug Interactions

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Sodium bicarbonateDolutegravir
Severe
How does the drug interact with Sodium Bicarbonate - 450G - 450G:
Co-administration of Sodium Bicarbonate - 450G and Dolutegravir reduces the levels of Dolutegravir, resulting in reduced effectiveness.

How to manage the interaction:
Although taking Dolutegravir and Sodium Bicarbonate - 450G together can result in an interaction, they can be taken together if prescribed by your doctor. However, if you experience symptoms like fever, chills, diarrhea, sore throat, muscle aches, red or inflamed skin, and pain or burning during urination, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
Sodium bicarbonateGefitinib
Severe
How does the drug interact with Sodium Bicarbonate - 450G - 450G:
Taking Sodium Bicarbonate - 450G with Gefitinib together can reduce the levels and treatment outcomes of Gefitinib.

How to manage the interaction:
Although taking Gefitinib and Sodium Bicarbonate - 450G together can cause an interaction, it can be taken if a doctor has suggested it. Contact your doctor if your symptoms do not improve. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat smaller meals more often.
  • Avoid smoking and alcohol consumption. Alcohol intake leads to increased production of stomach acid, thereby increasing acidity and heartburn.
  • Maintain a healthy weight by regular exercising.
  • Avoid lying down after eating as it causes acid reflux.
  • Avoid tight-fitting clothes as it might increase the pressure on the abdomen, leading to acid reflux.
  • Practise relaxation techniques and avoid stress by doing yoga or meditation.
  • Avoid foods such as high-fat, spicy food, chocolates, citrus fruits, pineapple, tomato, onion, garlic, tea, and soda. 
  • Avoid sitting continuously, as it may trigger acidity. Take a 5-minute break every hour by brisk walking or stretching.

Habit Forming

No

Therapeutic Class

ANTACIDS
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Alcohol

Unsafe

Avoid consumption of alcohol while taking Sodium Bicarbonate - 450G. Alcohol intake leads to increased production of stomach acid, thereby increasing acidity and heartburn.

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Pregnancy

Consult your doctor

Sodium Bicarbonate - 450G belongs to pregnancy category C. Consult your doctor if you are pregnant; your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Consult your doctor

Consult your doctor if you are breastfeeding. Your doctor will decide whether breastfeeding mothers can take Sodium Bicarbonate - 450G.

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Driving

Safe if prescribed

Sodium Bicarbonate - 450G is unlikely to affect your ability to drive and handle machinery.

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Liver

Consult your doctor

Dose adjustment may be needed. Consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Consult your doctor

Dose adjustment may be needed. Consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Consult your doctor

Sodium Bicarbonate - 450G should not be given to children unless prescribed by the doctor.

Have a query?

FAQs

Sodium Bicarbonate - 450G is an antacid that helps neutralize stomach acid during indigestion and heartburn. Sodium Bicarbonate - 450G may also be prescribed to make the blood or urine less acidic in certain conditions.

Sodium Bicarbonate - 450G has alkaline pH, which helps in neutralising the acidic pH in the stomach. Thereby, Sodium Bicarbonate - 450G helps to provide relief from acidity and heartburn.

Do not take Sodium Bicarbonate - 450G for longer than two weeks unless prescribed by the doctor. If there is no symptomatic improvement despite using Sodium Bicarbonate - 450G for 1-2 weeks, consult your doctor.

Sodium Bicarbonate - 450G can be taken with other medicines if prescribed by the doctor. However, you are advised to maintain a gap of 2 hours between Sodium Bicarbonate - 450G and other medicines.

Dry mouth could be a side-effect of Sodium Bicarbonate - 450G. Limiting caffeine intake, avoiding smoking, drinking water regularly and chewing sugar-free gum/candy might stimulate saliva and prevent drying of the mouth.

Country of origin

INDIA
Other Info - SOD0061

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Author Details

Veda MaddalaDoctor badge

Written By

Veda Maddala

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Aug 18, 2025 | 1:00 PM IST

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Reference

  1. https://www.accessdata.fda.gov/drugsatfda_docs/label/2005/077394lbl.pdf
  2. https://www.medicines.org.uk/emc/files/pil.3697.pdf
  3. https://dailymed.nlm.nih.gov/dailymed/fda/fdaDrugXsl.cfm?setid=3cb67478-1a51-4e7d-a529-79029655f5d9&type=display
  4. https://medlineplus.gov/druginfo/meds/a682001.html
  5. https://www.drugs.com/mtm/sodium-bicarbonate.html

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