Spegra Tablet 30's
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30 ₹3707.6
(₹123.59 per unit)
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90 ₹11122.9
(₹123.59 per unit)
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About Spegra Tablet
Spegra Tablet is used for the treatment of HIV-1 infection (human immunodeficiency virus type 1) in adults and children above 12 years weighing at least 40 kg.
Spegra Tablet contains Dolutegravir, Emtricitabine, and Tenofovir alafenamide. These medicines work together to block the activity of HIV integrase and reverse transcriptase enzymes that the virus needs to multiply, thereby reducing the amount of virus in the body and helping to treat HIV infection.
Take Spegra Tablet exactly as prescribed by your doctor. Swallow it whole with a glass of water, and do not crush or chew it. In some cases, Spegra Tablet may cause common side effects such as trouble sleeping, headache, nausea, and tiredness. Please talk to your doctor if these side effects persist or worsen.
Consult your doctor before taking Spegra Tablet if you are pregnant or planning to get pregnant. Avoid breastfeeding while taking Spegra Tablet . Spegra Tablet does not reduce the risk of getting HIV-1 infection through sexual contact; therefore, it is important to practise safe sex to avoid transmitting HIV to your partner.
Uses of Spegra Tablet
Spegra Tablet used to treat HIV-1 infection (human immunodeficiency virus type 1). The detailed uses of Spegra Tablet are as follows:
- Treatment of HIV-1 infection: Spegra Tablet helps reduce the amount of virus in the body and keeps the HIV-1 infection under control.
Health Queries
How can I find out whether I am HIV positive or negative?
Dr Y Thulasi
Pharm-D (Post baccalaureate)
Could you please provide information on HIV medications and where to consult a doctor?
Dr Y Thulasi
Pharm-D (Post baccalaureate)
I do not have HIV, but what are its symptoms?
Dr Y Thulasi
Pharm-D (Post baccalaureate)
After unprotected sex, is there any medication I can take to prevent STDs or HIV?
Dr Y Thulasi
Pharm-D (Post baccalaureate)
Have a query?
Directions for Use
- Spegra Tablet can be taken with or without food, or as advised by a doctor.
- Generally, Spegra Tablet is taken once daily, or as prescribed by your doctor.
- Swallow Spegra Tablet as a whole with a glass of water.
- Do not crush, chew, or break it.
Medicinal Benefits
- Spegra Tablet is an antiretroviral medication that is highly effective in treating HIV-1 infection.
- It keeps HIV infection under control by quickly reducing the amount of virus in the body.
- It helps recover and maintain immune system health by effectively suppressing HIV replication.
- It lowers the risk of developing AIDS (acquired immunodeficiency syndrome) and other HIV-related complications.
How Spegra Tablet Works
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- Hydrate your body: Drink enough water to prevent dehydration and headaches.
- Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
- Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
- Take rest: lie down in a quiet, dark environment.
- Cold or warm compresses can help reduce tension.
- Stay Upright: Maintain good posture to keep symptoms from getting worse.
- To treat headaches naturally, try acupuncture or massage therapy.
- Over-the-counter pain relievers include acetaminophen and ibuprofen.
- Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
- Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
- Frequent Headaches: If you get reoccurring headaches, consult your doctor.
- Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
- Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
- Divide your daily food intake into smaller, more frequent meals to reduce nausea.
- Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
- Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
- Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
- Use ginger (tea, ale, or candies) to help relieve nausea.
- Get adequate rest and also avoid strenuous activities that can worsen nausea.
- Talk to your doctor about taking anti-nausea medication if your nausea is severe.
- Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
- Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
- Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
- Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
- Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
- Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
- Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
- Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
- Rest well; get enough sleep.
- Eat a balanced diet and drink enough water.
- Manage stress with yoga and meditation.
- Limit alcohol and caffeine.
- Physical activities like walking or jogging might help boost energy and make you feel less tired.
- Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
- Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
- When standing up, do so slowly and carefully to avoid sudden dizziness.
- Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
- Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
- If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
- Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
- Keep regular sleeping hours.
- Don’t consume nicotine, caffeine, or alcohol in the hours leading up to bed.
- Practice relaxation exercises before bedtime.
- Regular physical activity can promote deeper and better sleep. However, avoid intense exercise within 2-3 hours of bedtime, as it can disrupt your sleep.
- If nightmares continue, cognitive behavioral therapy (CBT) may be a helpful treatment option. Your doctor may recommend CBT to address underlying issues and provide coping strategies to manage nightmares.
- Drink water or other clear fluids.
- To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
- Include bland foods like rice, toast, crackers, and rice in your diet.
- Avoid lying down immediately after eating as it may cause indigestion or heartburn.
- Avoid acidic and spicy food as it may cause indigestion.
What if I have taken an overdose of Spegra Tablet
Drug Warnings
- Inform your doctor if you are allergic to any of the ingredients of Spegra Tablet .
- Consult your doctor before taking Spegra Tablet if you are pregnant or planning to get pregnant.
- Avoid breastfeeding while undergoing treatment with Spegra Tablet .
- Practise safe sex to avoid transmitting HIV to your partner.
- Inform your doctor if you have hepatitis infection, diabetes, hypertension, or any liver/heart/kidney problems.
- Keep your doctor informed about any other medications you are taking to rule out any side effects or interactions.
Drug-Drug Interactions
Drug-Drug Interactions
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Taking Spegra Tablet with dofetilide may possibly reduce the blood levels and effects of Spegra Tablet. This can increase the risk of an irregular heart rhythm that may be serious.
How to manage the interaction:
Although taking Spegra Tablet with Dofetilide is not recommended, they can be taken together if prescribed by a doctor. However, contact your doctor if you experience drowsiness, lightheadedness, fainting, or irregular heartbeat. Do not stop taking any medications without consulting a doctor.
Combining these two medications may reduce overall effectiveness due to potential antagonistic effects (opposite actions).
How to manage the interaction:
Taking Spegra Tablet with Lamivudine is not recommended, but it can be taken if your doctor prescribes it. Contact your doctor if your symptoms do not improve. Do not stop taking any medication without consulting your doctor.
Coadministration of Didanosine with Spegra Tablet can increase the levels and risk of Didanosine side effects.
How to manage the interaction:
Taking Didanosine with Spegra Tablet is not recommended, please consult your doctor before taking it. It can be taken if your doctor prescribes it. However, if you experience severe headaches, confusion, weakness, trouble walking, muscle pain, or high fever, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
Combining Spegra Tablet and Streptozocin can increase the risk of kidney problems.
How to manage the interaction:
Taking Spegra Tablet with Streptozocin is not recommended, as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not stop using any medications without talking to your doctor.
Taking Spegra Tablet with magnesium oxide can reduce the effectiveness of Spegra Tablet.
How to manage the interaction:
Taking Magnesium oxide with Spegra Tablet together can result in an interaction, it can be taken if your doctor has advised it. However, take Spegra Tablet at least two hours before or six hours after the magnesium oxide dose. Do not stop using any medications without talking to a doctor.
Taking Spegra Tablet with ferrous sulfate can reduce the effectiveness of Spegra Tablet.
How to manage the interaction:
Although there is a possible interaction between Ferrous sulfate and Spegra Tablet, you can use these medicines together if prescribed by a doctor. It is advised to take Spegra Tablet either two hours before or six hours after taking a dose of Ferrous sulfate. Do not discontinue using any medications without consulting a doctor.
Co-administration of Spegra Tablet and Calcium gluconate may interfere with the absorption of Spegra Tablet and reduce its effectiveness.
How to manage the interaction:
Although there is an interaction, Calcium gluconate can be taken with Spegra Tablet if prescribed by the doctor. However, take Spegra Tablet 2 hours before or 6 hours after taking calcium gluconate. Do not stop using any medications without talking to a doctor.
Taking Spegra Tablet with oxcarbazepine may significantly decrease Spegra Tablet blood levels, making the medicine less effective in treating infection.
How to manage the interaction:
Although taking oxcarbazepine and Spegra Tablet together can result in an interaction, they can be taken together if prescribed by a doctor. Do not discontinue using any medications without consulting a doctor.
Taking Spegra Tablet with Attapulgite can reduce the effectiveness of Spegra Tablet.
How to manage the interaction:
Taking Spegra Tablet with Attapulgite together can possibly result in an interaction, they can be taken together if prescribed by your doctor. It is recommended to take Spegra Tablet at least two hours before or six hours after the attapulgite dose. Do not discontinue using any medications without consulting a doctor.
Taking Spegra Tablet with efavirenz can reduce the blood levels and effectiveness of Spegra Tablet.
How to manage the interaction:
Although taking Spegra Tablet and Efavirenz together can result in an interaction, they can be taken together if prescribed by your doctor. Do not discontinue any medications without consulting a doctor.
Drug-Food Interactions
Drug-Food Interactions
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St. John’S Wort
How to manage the interaction:
Consuming St.John's Wort while taking Spegra Tablet can increase the risk of side effects. Avoid consuming St.John's Wort with Spegra Tablet as it can lead to an interaction.
Diet & Lifestyle Advise
Dietary choices:
- Eat more lean meats, healthy fats, fruits, vegetables and whole-grain foods to support overall health.
Physical activity:
- Take a stroll in the garden or spend 30 minutes of your time doing some light physical activity daily, but avoid over-exertion if you feel too tired.
- Practice meditation and yoga to help maintain a healthy mind and body.
Preventive measures:
- Practise safe sex to prevent transmitting HIV to your partner.
- Use a condom during intercourse whenever possible.
- Educate yourself and your partner about pre- and post-exposure prophylaxis and ART (anti-retroviral therapy).
Oral hygiene:
- Take good care of your oral hygiene, as HIV often causes oral sores.
- Brush, floss, and scrape your tongue well and keep your mouth clean.
- See a dentist routinely to maintain oral health.
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Alcohol
Unsafe
It is not recommended to consume alcohol with Spegra Tablet . Please consult your doctor if you have any concerns.
Pregnancy
Caution
Please consult your doctor if you are pregnant. Your doctor will prescribe if the benefits are found to outweigh the risks.
Breast Feeding
Unsafe
Avoid breastfeeding while on treatment with Spegra Tablet .
Driving
Caution
Spegra Tablet may cause dizziness and tiredness. Do not drive if you experience any side effects after using Spegra Tablet .
Liver
Caution
Exercise caution before using Spegra Tablet in case of established liver disease. Please consult your doctor to address any concerns.
Kidney
Caution
Exercise caution before using Spegra Tablet in case of established kidney disease. Please consult your doctor to address any concerns.
Children
Unsafe
Spegra Tablet is not recommended for use in children under 12 years of age. Please consult your doctor in case of any concerns.
Heart
Caution
Spegra Tablet should be used with caution in patients with cardiovascular disease. Please inform your doctor if you have any pre-existing heart problems before using Spegra Tablet .
Geriatrics
Caution
Spegra Tablet should be given with caution in elderly patients due to an increased risk of side effects. It is important to inform a healthcare professional before use.
FAQs
Spegra Tablet is used for the treatment of HIV-1 infection (human immunodeficiency virus type 1) in adults and children above 12 years weighing at least 40 kg.
Spegra Tablet contains Dolutegravir, Emtricitabine, and Tenofovir alafenamide. These medicines work together to block the activity of HIV integrase and reverse transcriptase enzymes that the virus needs to multiply, thereby reducing the amount of virus in the body and helping to treat HIV infection.
It is not known if Spegra Tablet is safe for patients who have HIV-1 and hepatitis-B infections. Please consult your doctor for any concerns.
Do not stop taking Spegra Tablet without consulting your doctor, as it may reduce the effectiveness of anti-HIV therapy. Continue taking Spegra Tablet for as long as your doctor has prescribed it to you to treat your condition effectively. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Spegra Tablet .
Spegra Tablet might cause lactic acidosis (excess of lactic acid in the blood). Consult a doctor immediately if you experience stomach pain, vomiting, nausea, drowsiness, or deep, rapid breathing.
Take the missed dose as soon as you remember, unless it's almost time for your next dose. In this case, skip the missed dose and take your next dose at the regular time. Never take a double dose to make up for a missed one.
Avoid nursing while receiving Spegra Tablet therapy. Avoid alcohol consumption. It is critical to engage in safe sex to avoid transferring HIV to your partner.
Before taking the Spegra Tablet , let your doctor know about all your medical conditions, sensitivities, and all the medications you are using. And inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding.
Yes, Spegra Tablet is an anti-retroviral drug used in the treatment of HIV-1 infection.
Your doctor will determine the duration of Spegra Tablet based on your medical condition and response to treatment.
The recommended dosage of Spegra Tablet is one tablet taken orally once daily. However, dosage may vary depending on various factors, including medical condition and treatment response.
Dolutegravir, Emtricitabine and Tenofovir Alafenamide are the key active ingredients present in Spegra Tablet .
Spegra Tablet is not recommended for use in children under 12 years of age. Please consult your doctor in case of any concerns.
Taking more than the recommended dosage does not provide additional pain relief and can increase the risk of adverse effects.
Avoid consuming alcohol along with Spegra Tablet as it could lead to adverse effects.
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Reference
- https://www.medicines.org.uk/emc/files/pil.9313.pdf
- https://pubmed.ncbi.nlm.nih.gov/33010240/
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3312400/
- https://www.cdc.gov/hiv/basics/livingwithhiv/healthy-living.html
- https://pubmed.ncbi.nlm.nih.gov/25858605/
- https://en.wikipedia.org/wiki/Emtricitabine#:~:text=Mechanism%20of%20action,-This%20section%20does&text=Emtricitabine%20is%20an%20analogue%20of,RNA%20into%20new%20viral%20DNA.
- https://go.drugbank.com/drugs/DB09299
- https://www.medicines.org.uk/emc/product/9313/smpc#gref
