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Systaflam Gel is used to relieve pain and inflammation associated with musculoskeletal disorders, strain, sprain, arthritis, and low back pain. It blocks the release of certain chemical messengers in the brain that are responsible for causing pain and symptoms of inflammation, redness, and swelling. Also, it works on the brain and spinal cord centres to relieve muscle hardness or spasms and improve the pain and movement of muscles. It may cause side effects such as a burning sensation, irritation, itching and redness at the application site. Do not apply it to wounded or damaged skin.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
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More about the Product

Composition :

DICLOFENAC-1%W/W+MENTHOL-2%W/W+MEPHENESIN-5%W/W+METHYL SALICYLATE-5%W/W+TURPENTINE OIL-3%W/W

Manufacturer/Marketer :

Systopic Laboratories Pvt Ltd

Consume Type :

Topical

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Systaflam Gel

Systaflam Gel is a topical pain-relief medication formulated to manage localised muscle pain, joint stiffness, and swelling. It is commonly prescribed to treat acute discomfort caused by muscle sprains, strains, backaches, and minor sports injuries. Targeting the painful area directly through the skin, it provides localised comfort without the need for systemic oral medication.

For the best results, you must apply Systaflam Gel consistently as directed by your healthcare provider, typically a few times throughout the day. Because this is a topical preparation applied directly to the skin, you can use it regardless of your food schedule. Integrating gentle daily physical therapy and maintaining proper hydration can also support your recovery process during treatment.

While using Systaflam Gel, you may experience mild local reactions like temporary skin redness, warmth, or a tingling sensation at the application site. However, you should stop using the gel immediately and consult your doctor if you experience severe skin irritation, blistering, or signs of a serious allergic reaction. Always monitor how your skin responds during the first few days of application.

Talk to your doctor before starting this medicine if you have underlying health conditions such as asthma, stomach ulcers, or severe skin sensitivities. Do not use this product if you have open wounds, active skin infections, or if you have previously had a severe reaction to topical pain relievers. It is important to ensure your skin is completely intact before applying this medication.

Avoid using Systaflam Gel alongside other topical skin treatments or oral nonsteroidal anti-inflammatory drugs unless your doctor advises it, as this can increase your risk of side effects.

If you are pregnant, breastfeeding, or an older adult, consult your doctor or pharmacist before using this medicine. Diclofenac, an NSAID (Nonsteroidal Anti-Inflammatory Drugs) in this product, should be used with medical advice during pregnancy, especially in the third trimester, as it may affect the baby’s circulation by increasing the risk of premature closure of a blood vessel called the ductus arteriosus. Your doctor can guide you on whether this medicine is appropriate at any stage of pregnancy. 

Uses of Systaflam Gel

Your doctor may prescribe this medicine to treat several conditions, including:

  • Muscle strains and sprains: Relieve localised pain, swelling, and tenderness caused by overstretched or torn muscle fibres.
  • Joint pain and stiffness: Reduces inflammation and eases discomfort in affected joints, helping to restore normal movement.
  • Backache and neck pain: Targets deep-seated muscular tension and soreness along the spine and neck area.
  • Minor sports injuries: Speeds up recovery from acute, non-penetrating injuries by reducing localised swelling and pain.
     

Key Benefits

Your doctor may prescribe this medicine to treat several conditions, including:

  • Muscle strains and sprains: Relieve localised pain, swelling, and tenderness caused by overstretched or torn muscle fibres.
  • Joint pain and stiffness: Reduces inflammation and eases discomfort in affected joints, helping to restore normal movement.
  • Backache and neck pain: Targets deep-seated muscular tension and soreness along the spine and neck area.
  • Minor sports injuries: Speeds up recovery from acute, non-penetrating injuries by reducing localised swelling and pain.
     
Side effects of Systaflam Gel 25 gm
Here are the few steps for dealing with itching caused by drug use:
  • Report the itching to your doctor immediately; they may need to change your medication or dosage.
  • Use a cool, damp cloth on the itchy area to help soothe and calm the skin, reducing itching and inflammation.
  • Keep your skin hydrated and healthy with gentle, fragrance-free moisturizers.
  • Try not to scratch, as this can worsen the itching and irritate your skin.
  • If your doctor prescribes, you can take oral medications or apply topical creams or ointments to help relieve itching.
  • Track your itching symptoms and follow your doctor's guidance to adjust your treatment plan if needed. If the itching persists, consult your doctor for further advice.
  • Avoid scrubbing, scratching, and using products that contain fragrances.
  • Use a gentle, non-perfumed moisturizer daily.
  • Soak in warm water with colloidal oatmeal, it can relieve itching and dryness.
  • Applying calamine lotion can help with contact dermatitis and other types of rashes.
  • Use hydrocortisone creams, it can soothe itching and inflammation.
  • Wear loose, non-irritating clothing.
  • Protect your skin from the sun.
  • If the rash develops blisters or open sores, if spreads quickly or if causes significant discomfort or pain, immediately consult your doctor for the appropriate treatment.
  • Skin rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
  • Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
  • Protect your skin from extreme heat and try to apply wet compresses.
  • Soak in the cool bath, which gives a soothing impact to the affected area.

Directions for Use

  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Clean and dry the affected area and apply the gel by gently spreading it over the affected area.
  • Wash your hands after applying it, unless your hands are the affected area.
  • Avoid contact of the Systaflam Gel with the nose or eyes. In case of accidental contact with these areas, rinse with water thoroughly.

How Systaflam Gel Works

Systaflam Gel contains five active ingredients: diclofenac, mephenesin, menthol, turpentine oil, and methyl salicylate. Each ingredient helps reduce pain and discomfort in a different way: Diclofenac: Diclofenac is a non-steroidal anti-inflammatory drug (NSAID) that reduces the production of prostaglandins (natural chemicals in the body that cause pain, swelling, and inflammation). This helps decrease pain, tenderness, and swelling in the affected area. Mephenesin: Mephenesin is a muscle relaxant that helps reduce muscle tightness and discomfort. Although it can act on the central nervous system, the amount absorbed into the body from topical use is usually low when used as directed. Using more than recommended or applying it over large areas may increase the chance of effects such as drowsiness or dizziness. Menthol: Menthol creates a cooling sensation on the skin that helps reduce the feeling of pain by acting on local nerves. Turpentine oil and methyl salicylate: These ingredients create a mild warming sensation on the skin that can help distract from deeper muscle pain and provide temporary relief from soreness and stiffness. Use only the recommended amount, as excessive use may increase the risk of skin irritation or unwanted effects.
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Alcohol

Consult your doctor

It is unknown whether it is safe to consume alcohol with Systaflam Gel. However, as a precautionary measure, it is advisable not to take or limit alcohol.

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Pregnancy

Consult your doctor

Systaflam Gel is not recommended during pregnancy unless your doctor considers it essential. Please consult the doctor. Your doctor will weigh the benefits and potential risks before prescribing them.

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Breast Feeding

Consult your doctor

Systaflam Gel should not be used in nursing mothers unless necessary. So, inform your doctor if you are a nursing mother. Your doctor will weigh the benefits and potential risks before prescribing Systaflam Gel.

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Driving

Safe if prescribed

Systaflam Gel does not impact your ability to drive or operate machinery.

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Liver

Consult your doctor

Limited information was available about using Systaflam Gel in patients with liver disease. If you have concerns about utilising Systaflam Gel in patients with liver disease, please visit your doctor. Only if the benefits outweigh the risks will your doctor prescribe.

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Kidney

Consult your doctor

Limited information was available about using Systaflam Gel in patients with kidney disease. If you have concerns about utilising Systaflam Gel in patients with kidney disease, please visit your doctor. Your doctor will prescribe only if the benefits outweigh the risks.

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Children

Unsafe

Systaflam Gel is not recommended for children as safety and effectiveness have not been established.

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Heart

Unsafe

Systaflam Gel is not recommended for use in heart patients as its safety and efficacy are not established.

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Geriatrics

Caution

Systaflam Gel should be given with caution in elderly patients due to an increased risk of side effects. Seek medical advice before using Systaflam Gel.

What if I have taken an overdose of Systaflam Gel

While accidental overdose is highly unlikely when Systaflam Gel is used topically, applying it over excessively large areas of the body or swallowing the gel can lead to serious health complications. If the product is swallowed or used excessively, seek immediate medical attention or contact a poison control centre right away.

Diet & Lifestyle Advise

  • Stay hydrated: Drink plenty of water throughout the day to keep your muscles properly hydrated, which helps reduce the frequency of muscle cramps.
  • Maintain a healthy weight: Managing your weight helps decrease the daily physical stress placed on weight-bearing joints like your knees, hips, and lower back.
  • Incorporate gentle movement: Do light activities such as walking or swimming to keep your joints flexible without putting too much pressure on them.
  • Apply ice or heat safely: Use an ice pack for swelling during the first 48 hours after an injury. Later, gentle heat may help relax stiff muscles, but do not apply heat directly over the area where the gel has been used.
     
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How Soon It Starts Working

The time required for Systaflam Gel to start to work: The time required for Systaflam Gel to start to work is 15 to 30 minutes after application. The time for which the effects of Systaflam Gel last: The effect of Systaflam Gel lasts for 8 to 12 hours.

Storage

•Store Systaflam Gel at controlled room temperature, ideally between 15°C and 30°C (59°F to 86°F).

What if you forget to take Systaflam Gel

If you forget to apply Systaflam Gel, apply it as soon as you remember. However, if it is almost time for your next scheduled application, skip the missed application and continue with your regular routine. Do not apply a double amount to make up for a missed application.

Drug Warnings

  • Avoid Heat Exposure Before or After Application: Do not apply this medicine immediately before or after a hot bath, shower, or heat therapy. Heat may increase absorption through the skin and may raise the chance of skin irritation or other side effects.
  • Check Your Skin Before Use: Avoid applying this medicine to sunburned, windburned, dry, cracked, irritated, or damaged skin.
  • Avoid Contact With Sensitive Areas: Keep this medicine away from your eyes, nose, mouth, and other sensitive areas. If it accidentally gets into these areas, rinse thoroughly with plenty of cool water.
  • Do Not Cover With Airtight Dressings: Avoid covering the treated area with plastic wrap or airtight bandages unless your doctor advises it, as this may increase absorption.
  • Monitor Pain Relief: Stop using this medicine and consult your healthcare provider if your pain does not improve after one week of regular use or if your symptoms become worse.
  • Avoid Excessive Methyl Salicylate Exposure: Do not apply more than the recommended amount or use this medicine over large areas of the body. Keep it away from children, as swallowing it or using too much can cause harmful levels of salicylate (a pain-relieving chemical) in the body. Seek medical help if symptoms such as ringing in the ears, nausea, vomiting, confusion, or unusual breathing changes occur.
     

Drug-Drug Interactions

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Drug-Drug Interactions:

Inform your doctor about all medicines and topical products you use, including:

  • Other topical skin products: Using creams, ointments, gels, or lotions on the same area may increase skin irritation or affect how this medicine is absorbed.
  • Oral NSAID painkillers (such as ibuprofen, aspirin, or naproxen): Using this gel along with oral NSAIDs may increase the chance of side effects affecting the whole body, such as stomach irritation or kidney problems.
  • Blood thinners (such as warfarin or newer anticoagulants): Diclofenac and methyl salicylate may increase bleeding risk in some people. If you take blood-thinning medicines, consult your doctor before using this gel.
  • Topical corticosteroids or steroid creams: Using steroid creams on the same area may increase skin sensitivity or irritation. Ask your doctor before combining multiple topical medicines.


Drug-Disease Interactions:

Inform your doctor if you have any of the following conditions:

  • Skin infections, eczema, or damaged skin: Do not apply this medicine to infected, broken, or severely irritated skin, as it may worsen irritation.
  • Asthma or sensitivity to painkillers: If aspirin or similar painkillers trigger breathing problems for you, tell your doctor before using this product. Even though very little of this gel enters your bloodstream, it may still trigger reactions in sensitive individuals.
  • Bleeding disorders: If you have a condition that increases bleeding risk, your doctor should review whether this medicine is suitable for you.
     
No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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FAQs

Systaflam Gel is used to relieve pain and inflammation associated with musculoskeletal disorders, strain, sprain, arthritis, and low back pain.
Systaflam Gel combines five medicines: Diclofenac, Mephenesin, Menthol, Turpentine oil and Methyl salicylate. Diclofenac is a non-steroidal anti-inflammatory drug (NSAID) that blocks the release of certain chemical messengers in the brain, which are responsible for causing pain and symptoms of inflammation, redness, and swelling. Mephenesin is a muscle relaxant (that relaxes the muscle and treats muscle pain). It works on the brain and spinal cord centres to relieve muscle hardness or spasms and improve the pain and movement of muscles. Methyl salicylate and Menthol are topical analgesics (applied directly to alleviate pain). They work initially by cooling the skin, followed by warming it up. This action helps improve blood circulation and relieve pain. Turpentine Oil is a lubricant.
Avoid concomitant use of Systaflam Gel with other topical products such as cosmetics, sunscreens, lotions, moisturizers, insect-repellent creams, and other gels.
Please do not take any NSAID/painkiller medicines along with Systaflam Gel as it could increase the risk of ulceration, perforation, and bleeding in the stomach and intestine. Inform your doctor before using Systaflam Gel if you are taking any NSAIDs orally.
No, the use of Systaflam Gel is contraindicated on the broken or cut wound skin. It should be only applied topically on the uppermost skin surfaces (epidermis). It should not be applied in the nostrils, vagina or anus.
No, it is not advised to use Systaflam Gel in patients with severe heart failure.
Avoid or limit exposure to natural or artificial sunlight as Systaflam Gel may cause ultraviolet light-induced skin tumours.
This medicine may provide temporary relief from localised joint pain and stiffness associated with arthritis. However, this specific combination product is mainly used for short-term relief of muscle and joint discomfort, and its long-term safety and effectiveness for chronic arthritis management have not been fully established. If you have ongoing arthritis symptoms, discuss a long-term treatment plan with your doctor. They can recommend the most appropriate options based on your condition.
No. Avoid applying heating pads, hot compresses, or other sources of heat over the treated area. Heat may increase absorption of the medicine and may raise the risk of skin irritation or other unwanted effects. Follow your doctor's instructions if you need additional heat therapy for your condition.
You should consult your healthcare provider before using Systaflam Gel during any stage of pregnancy or while breastfeeding. The concern is greater during the third trimester because diclofenac may increase the risk of premature closure of a blood vessel called the ductus arteriosus in the baby. Your doctor will decide whether the benefits of using this medicine outweigh the possible risks.
Rinse your eyes thoroughly with plenty of cool, clean water immediately. If you experience persistent redness, pain, or changes in your vision, seek medical attention right away.
This medicine is applied to the skin and usually enters the bloodstream in very small amounts. At recommended doses, drowsiness or dizziness is uncommon. Because this gel contains mephenesin, a muscle relaxant, some people may feel mildly drowsy, especially if they use too much, apply it over a large area, or use it more often than advised. Contact your doctor if you experience unusual tiredness, dizziness, or other concerning symptoms.
It is best to wait at least one to two hours after applying the gel before bathing or showering to ensure the medication has been fully absorbed by your skin.
Some active ingredients in topical pain relievers can interact with blood thinners and increase the risk of bleeding, even when absorbed through the skin.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

Systopic Laboratories Pvt. Ltd., 101, Pragati Chambers, Commercial Complex, Ranjit Nagar, New Delhi-110008
Other Info - SYS0005

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