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Toplap Gel is used to prevent pain and produce local numbness (anaesthesia) on the skin before surgical procedures or injections. It contains Lidocaine and Prilocaine which work by preventing the initiation and conduction of impulses. In some cases, this medicine may cause side effects such as application site reactions (burning, itching, redness, and irritation). It is for external use only.

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Written By Lakshmithulasi Yarragunta , PharmD (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Manufacturer/Marketer :

Torrent Pharmaceuticals Ltd

Consume Type :

Topical

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Toplap Gel

Toplap Gel is a prescription topical anaesthetic cream designed to temporarily numb the surface of the skin. It is used to prevent pain during minor medical, surgical, or cosmetic procedures, such as needle punctures, skin grafts, or superficial laser treatments. By temporarily blocking pain signals in the treated area, this cream helps make these interventions significantly more comfortable.

This medication is applied only when needed before a scheduled procedure, rather than on a regular daily schedule. You should apply it to clean, dry, and intact skin as directed by your healthcare provider. Keeping your skin well-hydrated by drinking plenty of water and avoiding harsh chemical exfoliants prior to your procedure can help maintain a healthy skin barrier and support optimal results.

While using Toplap Gel, you may notice temporary local reactions like skin paleness, mild redness, or a slight burning sensation where the cream was applied. These minor reactions typically fade shortly after the cream is wiped away. However, if you experience severe burning, swelling, skin blistering, or signs of a serious allergic reaction, you must seek medical attention immediately.

Do not take this if you have a history of drug allergies, especially to other local anesthetics. Before using this cream, inform your doctor if you have a rare blood disorder called methemoglobinemia, severe liver damage, or a genetic condition called G6PD deficiency. This medicine should not be applied to open wounds, broken skin, infected areas, or near the eyes and ears.

Certain heart medications can interact with this cream, so it is important to provide your healthcare provider with a complete list of your current medicines. If you are pregnant, planning to become pregnant, breastfeeding, or caring for an elderly individual, consult your doctor before using this product to ensure it is safe for your specific situation.

Uses of Toplap Gel

Toplap Gel is used to prevent pain during minor medical, surgical, or cosmetic procedures. The detailed uses of Toplap Gel are as follows:

  • Minor skin procedures: Toplap Gel numbs the skin before needle insertions, blood draws, or the insertion of intravenous (IV) lines, making the needle stick virtually painless.
  • Cosmetic dermatological treatments: It is used to minimise discomfort during laser hair removal, tattoo application or removal, and dermal filler injections.
  • Superficial surgical interventions: The cream helps prevent pain during minor skin surgeries, such as wart removal, skin biopsies, or superficial skin graft harvesting.
     

Key Benefits

Toplap Gel helps provide temporary local anaesthesia by numbing the skin at the site of application. By blocking pain signals in a specific area, it helps make medical procedures more comfortable without affecting your alertness.

  • Provides Targeted Pain Relief: By numbing the treated area, Toplap Gel helps prevent pain during procedures such as injections, minor surgeries, or cosmetic treatments while allowing you to remain awake and comfortable.
  • Helps Reduce Procedure-Related Anxiety: By minimising the pain associated with needles and minor procedures, Toplap Gel helps reduce fear and anxiety, making medical visits more comfortable for both adults and children.
  • Supports Safer and More Comfortable Procedures: By providing effective local anaesthesia, Toplap Gel helps patients remain still and comfortable during procedures, enabling healthcare professionals to perform treatments more efficiently and accurately.
     

Directions for Use

  • Generally, you may need to use it at home up to 4 hours prior to your surgery/procedure. However, follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
  • Check the directions on the label and use it as advised by the doctor. Your doctor will tell you how much to use and how long to leave it on your skin. Follow these instructions carefully.
  • Do not cover the treated area with a bandage or plastic wrap unless advised by the doctor.

How Toplap Gel Works

Toplap Gel contains two active ingredients: lidocaine and prilocaine. Both of these substances belong to a class of medications called local anaesthetics. They work together by temporarily blocking the pathway of pain signals along your nerves. Lidocaine works rapidly to penetrate the skin surface and stabilise the neuronal membrane by preventing the flow of sodium ions, which are necessary for initiating nerve impulses. Prilocaine complements this action by also blocking sodium channels, extending the duration and depth of the numbing effect. Together, they prevent the nerve endings in your skin from sending pain messages to your brain, resulting in a temporary loss of feeling in the treated area.
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Alcohol

Caution

You are recommended to avoid alcohol consumption while using Toplap Gel. Alcohol intake, along with Toplap Gel, may cause increased drowsiness.

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Pregnancy

Caution

Toplap Gel is pregnancy category B drug. If a lady is pregnant, they can use the medicine only after the doctor's recommendation. Please consult your doctor if you have any concerns regarding this. Your doctor will prescribe you Toplap Gel only if the benefits outweigh the risks.

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Breast Feeding

Caution

Toplap Gel can only be used in breastfeeding mothers after the doctor's suggestion.

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Driving

Caution

Toplap Gel may cause drowsiness; do not drive or operate heavy machinery if you feel drowsy.

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Liver

Caution

Toplap Gel should be used with caution in patients with liver impairment/liver disease. Dose adjustment may be needed. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Toplap Gel is safe if prescribed by a doctor in patients with serious kidney disease. Please ask your doctor about all of your liver problems.

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Children

Caution

Toplap Gel is to be used on children only when prescribed by the doctor.

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Heart

Consult your doctor

Please inform your doctor if you have a history of heart disease before using Toplap Gel. Your doctor will prescribe it only if the benefits outweigh the risks.

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Geriatrics

Consult your doctor

Limited information available for use of Toplap Gel in elderly patients. Please consult your doctor.

What if I have taken an overdose of Toplap Gel

If you accidentally apply too much cream, leave it on for too long, or apply it to a large area of broken skin, your body may absorb too much medicine. Wipe off the excess cream immediately and seek emergency medical attention right away.

Diet & Lifestyle Advise

  • Protect the numbed skin: Avoid scratching, rubbing, or exposing the treated skin to extreme heat or cold while it is numb, as you could easily injure the area without feeling it.
  • Hydrate your skin from within: Drink plenty of water in the days leading up to your skin procedure to support healthy skin barrier function and recovery.
  • Avoid skin irritants: Do not apply harsh chemical peels, strong exfoliating scrubs, or alcohol-based skincare products to the target area for at least 24 to 48 hours before applying Toplap Gel.
  • Keep the area clean: Ensure the skin is completely washed with mild soap and water and thoroughly dried before applying the cream to prevent trapping dirt or bacteria under the protective dressing.
     
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How Soon It Starts Working

The time required for Toplap Gel to start to work: The time required for Toplap Gel to show its action is unknown. The time for which the effects of Toplap Gel last: Toplap Gel effect lasts for 6 to 8 hours.

Storage

•Store Toplap Gel at room temperature, ideally between 15°C and 30°C (59°F to 86°F). •Do not freeze this medication, and keep the tube tightly closed when not in use to prevent the cream from drying out.

What if you forget to take Toplap Gel

Because this cream is typically applied only once as a single dose before a scheduled medical or cosmetic procedure, missing a dose usually means you forgot to apply it at the correct time before your appointment. If this happens, contact your doctor's office immediately to ask if the procedure can still go ahead or if you need to reschedule.

Drug Warnings

  • Inspect the tube before use; do not use the cream if the tube is punctured, damaged, or if the cream has changed colour or consistency.
  • Never apply this cream to open wounds, cuts, scrapes, severe burns, or active skin infections, as this can cause the body to absorb the medicine too rapidly and lead to toxicity.
  • Avoid getting the cream in or near your eyes, nose, mouth, or ears. If accidental contact occurs, rinse the area thoroughly with plenty of lukewarm water immediately.
  • Do not leave the cream on the skin for longer than the maximum time recommended by your doctor, as prolonged application increases the risk of serious systemic side effects.
  • If you are applying this cream to a child, ensure they are supervised closely so they do not touch the treated area or accidentally put the cream in their mouth.
     

verifiedApollotooltip
  • Class III heart rhythm medicines (such as amiodarone): Combining these with Toplap Gel can increase the risk of heart-related side effects, as both can affect cardiac function.
  • Other local anaesthetics: Using other numbing agents at the same time can increase the overall level of anaesthetic in your body, raising the risk of toxicity.
  • Medicines that trigger methaemoglobinemia (such as sulphonamide antibiotics or nitrates): When used together, these can increase the risk of a serious blood oxygen disorder.
     

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verifiedApollotooltip

No clinically significant food interactions are known with Toplap Gel when used as directed. 

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[LOCAL ANESTHETICS]

FAQs

Toplap Gel belongs to the class of local anaesthetics known as numbing medication, which is used to produce local numbness (anaesthesia) on the skin before surgical procedures or injections.
Toplap Gel contains Lidocaine and Prilocaine. Together, Toplap Gel blocks pain signals from the nerves to the brain, decreasing the pain sensation.
Do not use Toplap Gel after expiry. Expiry refers to the last date that the manufacturer guarantees the full potency and safety of the drug. Check the expiry date from time to time and properly discard the Toplap Gel after expiry or return it to your pharmacist for proper disposal.
Be careful and check that no injury occurs in the numb area. You will not feel the pain, but it will hurt you the most after the action of Toplap Gel ends.
A person 65 or older should use Toplap Gel with caution, as directed by the doctor, as the chances of side effects increase in older people.
The anaesthetic effect of Toplap Gel varies based on application time and treatment area. On intact skin, it lasts 1-2 hours after removal, while on genital mucosa, it lasts 15-20 minutes. Please consult a doctor for specific guidance.
The side effects of Toplap Gel include swelling, burning, itching, skin rash, and white or red skin at the application site. Most of these side effects do not require medical attention and resolve gradually over time. However, consult the doctor if any of these symptoms persist or worsen.
Toplap Gel should be applied to intact skin before the surgical procedure. Apply a thin layer with clean and dry hands on the skin. You can also apply it with a piece of clean cotton wool or a gauze swab. Gently rub the medicine into the skin until it dissolves. Please wash your hands thoroughly before and after using it.
Yes, this cream can be used to reduce needle pain in children, but it must be applied under strict medical supervision. The dosage and application area must be carefully controlled based on the child's age and weight to prevent serious side effects. Talk to your doctor or pharmacist before using it on a child.
If the cream gets into your eyes, rinse them immediately with a large amount of lukewarm water or saline solution. Keep rinsing for several minutes and protect the eye until feeling returns, as you may not feel particles that could cause scratches. Contact your doctor or seek medical advice immediately.
Yes, because Toplap Gel is a topical cream that only numbs the specific area of skin where it is applied, it does not typically affect your ability to drive or operate machinery. However, if you feel dizzy, confused, or unusually sleepy after application, avoid driving and talk to your doctor right away.
The active ingredients can cross the placenta and may enter breast milk in small quantities. While topical use generally results in very low absorption, you should only use this cream during pregnancy or breastfeeding if clearly needed and recommended by your healthcare provider. Talk to your doctor to weigh the risks and benefits.
No, you should never apply heat, such as a heating pad, to the area where Toplap Gel has been applied. Heat can increase blood flow to the skin, causing your body to absorb the medicine much faster, which significantly increases the risk of severe side effects. Talk to your doctor if you have questions about proper application.

Disclaimer

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Country of origin

India

Manufacturer/Marketer address

Off. Ashram Road, Ahmedabad - 380 009., Gujarat, India.
Other Info - TOP0486
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