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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Trascepa 1000 Softgel Capsule is used to lower the high cholesterol together with lifestyle changes (diet, weight loss, exercise). It contains Icosapent Ethyl, which works by decreasing the amount of triglycerides and other fats made in the liver. You may experience side effects like musculoskeletal pain, peripheral oedema, constipation, gout, atrial fibrillation, arthralgia (pain in a joint), and oropharyngeal (middle part of the throat) pain.

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Manufacturer/Marketer :

Adn Lifesciences Pvt Ltd

Consume Type :

Oral

Expires on or after :

Return Policy :

Not Returnable

About Trascepa 1000 Softgel Capsule

Trascepa 1000 Softgel Capsule is used together with lifestyle changes (diet, weight loss, exercise) to lower high cholesterol, increased cholesterol levels, and triglycerides in the blood. High cholesterol is a condition in which you have high levels of lipids (fats) in your blood.

Trascepa 1000 Softgel Capsule contains Icosapent Ethyl, which works by decreasing the amount of triglycerides and other fats made in the liver. This helps lower the chance of a heart attack, stroke, or other heart issues that need to be hospitalised in some patients with high triglyceride levels, heart disease, or diabetes who also have two or more additional heart disease risk factors.

In some cases, you may experience side effects like musculoskeletal pain, peripheral oedema, constipation, gout, atrial fibrillation, arthralgia (pain in a joint), and oropharyngeal (middle part of the throat) pain. If the side effects persist, contact your doctor.

Avoid taking Trascepa 1000 Softgel Capsule if you are allergic to Icosapent Ethyl or any other component in this medicine. It is not recommended during pregnancy, breastfeeding, or for children and young adults under 18.

Uses of Trascepa 1000 Softgel Capsule

Trascepa 1000 Softgel Capsule is used in the treatment of High cholesterol (Hypertriglyceridemia). The detailed uses of Trascepa 1000 Softgel Capsule are as follows:

  • Cardiovascular risk reduction: Trascepa 1000 Softgel Capsule is used alongside statin therapy to reduce the risk of heart attack, stroke, and other cardiovascular events in adults with established heart disease or diabetes and additional risk factors.
  • Severe hypertriglyceridemia: Trascepa 1000 Softgel Capsule is used with a low-fat, low-cholesterol diet to lower very high triglyceride levels (≥500 mg/dl) in adults. Elevated triglycerides can increase the risk of pancreatitis and cardiovascular disease.
  • 3 fatty acid therapy: As a purified form of eicosapentaenoic acid (EPA), Trascepa 1000 Softgel Capsule helps regulate lipid metabolism and reduce inflammation, without significantly raising LDL cholesterol like some other omega-3 formulations.

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Directions for Use

  • Trascepa 1000 Softgel Capsule can be taken with food or as advised by the doctor.
  • It is usually recommended to take twice daily; however, follow your doctor’s advice regarding the dosage and duration.
  • Swallow Trascepa 1000 Softgel Capsule as a whole with water.
  • Do not crush, break or chew it.

Key Benefits

  • Trascepa 1000 Softgel Capsule contains Icosapent Ethyl, a lipid-lowering medicine belonging to the group of antilipemic (lipid-regulating) agents. It helps reduce high triglyceride levels and improves the overall cholesterol profile.
  • It works by decreasing the production of triglycerides and other fats in the liver.
  • It is used along with lifestyle modifications such as diet control, weight management, and exercise for better heart protection.
  • It helps lower the risk of heart attack, stroke, and other serious cardiovascular events.
  • It is especially beneficial in adults with high triglyceride levels who also have heart disease or diabetes with additional cardiovascular risk factors.
  • It supports long-term heart health by reducing fat buildup in blood vessels and improving blood flow.

How Trascepa 1000 Softgel Capsule Works

Trascepa 1000 Softgel Capsule contains Icosapent Ethyl, which works by decreasing the amount of triglycerides and other fats made in the liver. Reduced cholesterol lowers the chance of a heart attack, stroke, or other heart issues that need to be hospitalised in some patients with high triglyceride levels, heart disease, or diabetes who also have two or more additional heart disease risk factors.

Storage

Store in a cool and dry place away from sunlight
Side effects of Trascepa 1000 Softgel Capsule
  • Wear compression garments like stockings, sleeves, or gloves to apply pressure and help stop fluid from building up, especially after the swelling goes down.
  • Move around and do exercises to help the fluid circulate, especially in swollen limbs. Ask your doctor for specific exercises.
  • Raise the swollen area above your heart level several times a day, even while sleeping, to help reduce swelling.
  • Gently massage the swollen area with firm but not painful pressure.
  • Keep the swollen area clean and moisturized to prevent injury and infection.
  • Reduce salt intake to help prevent fluid from building up and worsening the swelling, as advised by a doctor.
  • If the swelling does not get better after a few days of home treatment or worsens, consult your doctor right away.
  • Drink plenty of water to eliminate uric acid.
  • Avoid purine-rich foods such as red meat, organ meats, certain seafood (sardines, anchovies) and too much alcohol.
  • Regularly do low impact exercises like swimming or walking.
  • To reduce pain and swelling, apply ice packs to the affected area.
  • Take rest and avoid activities that strain the affected joint.
  • Elevate the affected joint to encourage fluid drainage.
  • Aim for weight loss and maintain a healthy body weight to reduce the risk of gout.
Here are the steps to manage Joint Pain caused by medication usage:
  • Please inform your doctor about joint pain symptoms, as they may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Your doctor may prescribe common pain relievers if necessary to treat joint discomfort.
  • Maintaining a healthy lifestyle is key to relieving joint discomfort. Regular exercise, such as low-impact sports like walking, cycling, or swimming, should be combined with a well-balanced diet. Aim for 7-8 hours of sleep per night to assist your body in repairing and rebuilding tissue.
  • Applying heat or cold packs to the affected joint can help reduce pain and inflammation.
  • Please track when joint pain occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • If your joint pain is severe or prolonged, consult a doctor to rule out any underlying disorders that may require treatment.
  • Throat pain can worsen if there is no proper rest for your throat.
  • Drink plenty of warm fluids and frequently gargle with salt water.
  • Humidify the surrounding air using a humidifier, as dry air may increase dryness and throat pain.
  • Consider taking lozenges or hard candy throat pain relievers, which give a soothing effect.
  • Take enough rest and stay in warm places to reduce pain quickly.

What if I have taken an overdose of Trascepa 1000 Softgel Capsule

Do not take more than the prescribed dose. Using more medication will not improve your symptoms; instead, it may cause poisoning or serious side effects. If you suspect that you may have overdosed on Trascepa 1000 Softgel Capsule or observe any side effects, please go to the emergency department of the closest hospital or nursing home.

Drug Warnings

  • Before taking Trascepa 1000 Softgel Capsule , let your doctor know about all your medical conditions (especially liver or kidney impairment, atrial fibrillation, muscle problems and bleeding disorders), sensitivities or allergic conditions, and all medications you are using.
  • Avoid drinking alcohol while on this medication, as it can raise triglyceride levels and may increase your risk of liver damage.
  • It is not advised during pregnancy, for children, or young adults under the age of 18.
  • Consult your doctor right away if you become pregnant while taking Icosapent Ethyl.
  • Let your doctor know if you are taking any other medicines.

Drug-Drug Interactions

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No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

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ICOSAPENT ETHYL-1000MGTyramine-containing food

Drug-Food Interactions

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ICOSAPENT ETHYL-1000MGTyramine-containing food
Common Foods to Avoid:
Fish

How to manage the interaction:
It is obtained from oil of fish and has a risk of allergy in patients with known hypersensitivity. Patients with known hypersensitivity to fish and/or shellfish should discontinue Trascepa 1000 Softgel Capsule and seek medical attention if any reactions occur.

Diet & Lifestyle Advise

  • Try aromatherapy, yoga, and meditation to help relax your body and mind.
  • Try to do breathing exercises to get more oxygen.
  • Eat a healthy diet, especially rich in soluble fibre like beans, legumes, whole grains, flax, apples, and citrus fruits.
  • Try to replace most of your saturated fats with unsaturated fats that can reduce total cholesterol and LDL cholesterol quickly; avocados, olive oil, fatty fish, and nuts contain lots of heart-healthy unsaturated fats, so it’s beneficial to eat them regularly.
  • Try to adopt a Mediterranean-style diet rich in olive oil, fruits, vegetables, nuts, whole grains, and fish, and low in red meat and most dairy.
  • Try to give priority to more fruits and veggies in your daily meals, as these contain antioxidants which help to lower LDL.
  • Minimise the intake of added sugar. The American Heart Association (ADA) recommends that one should not eat more than 100 calories (25 grams) of added sugar for women and children and no more than 150 calories (37.5 grams) for men every day.
  • The American Heart Association recommends that sodium chloride (table salt) should not exceed 2,300 mg per day as part of a healthy eating pattern.
  • As a precautionary measure, do not consume alcohol and quit smoking.

Habit Forming

No

Therapeutic Class

[ANTILIPEMICS]

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Alcohol

Safe if prescribed

While using this medication, avoid consuming alcohol because it can elevate triglyceride levels and increase your risk of liver damage.

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Pregnancy

Consult your doctor

Trascepa 1000 Softgel Capsule is not recommended during pregnancy as it may cause major birth defects.

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Breast Feeding

Consult your doctor

If you are breastfeeding, inform your doctor before taking Trascepa 1000 Softgel Capsule .

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Driving

Safe if prescribed

Trascepa 1000 Softgel Capsule has negligible influence on the ability to drive and use machines.

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Liver

Consult your doctor

Caution should be exercised while using Trascepa 1000 Softgel Capsule in patients with hepatic impairment. Your doctor may monitor levels of alanine aminotransferase (ALT) and aspartate aminotransferase (AST). So, inform your doctor before receiving Trascepa 1000 Softgel Capsule if you have had a liver impairment.

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Kidney

Consult your doctor

It has not been studied in patients with kidney impairment. So, inform your doctor before receiving Trascepa 1000 Softgel Capsule if you have had kidney problems. Your doctor will prescribe only if the benefits outweigh the risks.

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Children

Safe if prescribed

Trascepa 1000 Softgel Capsule is not recommended for children younger than 18 years old.

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Heart

Trascepa 1000 Softgel Capsule is generally safe for heart patients if prescribed, but should be used under medical supervision.

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Geriatrics

Consult your doctor

Limited information available about the use of Trascepa 1000 Softgel Capsule in geriatric patients. Please consult your physician.

FAQs

Trascepa 1000 Softgel Capsule is used together with lifestyle changes (diet, weight loss, exercise) to lower high cholesterol or increased cholesterol levels and triglycerides in the blood.

Trascepa 1000 Softgel Capsule contains Icosapent Ethyl work, which works by decreasing the amount of triglycerides and other fats made in the liver.

In a clinical investigation, Trascepa 1000 Softgel Capsule was known to cause an increased risk of bleeding. Patients taking antithrombotic drugs such as aspirin, clopidogrel, or warfarin had a higher risk of bleeding. If you have any concerns, please consult your healthcare practitioner.

There is no strong evidence to suggest that taking Trascepa 1000 Softgel Capsule will reduce fertility in either men or women. However, it is advisable to consult a doctor before taking it if you are likely to get pregnant or are pregnant.

Increase your daily diet with fibre, fruits, vegetables, whole grains and fish, and cut saturated fat as well. Stop smoking and drinking, and try to work out every day as well.

No, you should not stop taking Trascepa 1000 Softgel Capsule without consulting your doctor. Please take advice from the doctor before quitting.

Yoghurt is a probiotic that can help lower the raised cholesterol level if taken with Trascepa 1000 Softgel Capsule . Yoghurt eaters have a better metabolic profile than those who do not eat yoghurt.

Country of origin

India
Other Info - TRA1044

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