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Trigaine Solution 60 ml
Trigaine Solution 60 ml
Trigaine Solution 60 ml
Trigaine Solution is used to treat hair loss. It works by blocking certain enzymes that cause hair loss, improving blood circulation, and stimulating hair growth. In some cases, this medicine may cause side effects such as headache, itching, or irritation at the site of the application. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions. It is for external use only.
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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

AZELAIC ACID-1.5%W/V+MINOXIDIL-2%W/V+TRETINOIN-0.025%W/V

Manufacturer/Marketer :

Apple Therapeutics Pvt Ltd

Consume Type :

Topical

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Trigaine Solution

Trigaine Solution belongs to a class of medicines called dermatological used to treat hair loss. Alopecia (hair loss) is the thinning or loss of hair on the scalp or any part of the body.

Trigaine Solution is a combination of three drugs: Azelaic acid, Minoxidil (vasodilator), and Tretinoin (a form of vitamin A). Azelaic acid is a naturally occurring acid that works by blocking a 5-alpha-reductase enzyme in the body that converts testosterone (male hormone) into dihydrotestosterone which causes hair loss. Thereby, it reduces dihydrotestosterone levels and slows down hair loss. Minoxidil widens the blood vessels and improves blood circulation to the hair follicles. Thus, it prevents hair loss and stimulates hair growth. Tretinoin is a form of vitamin A that promotes hair follicle growth on the scalp.

Use Trigaine Solution as suggested by your doctor. In some cases, you may experience headaches, itching, or irritation at the site of the application. Most of these side effects of Trigaine Solution do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Trigaine Solution or any other medicines, please tell your doctor. Trigaine Solution is not recommended for children below 18 years of age. If you are pregnant or breastfeeding, please consult a doctor before using Trigaine Solution. You are recommended to avoid using Trigaine Solution if your scalp is irritated, infected, painful, inflamed, or red. If you experience unwanted facial hair growth, scalp redness or irritation, and swelling in hands and legs, avoid using Trigaine Solution and consult a doctor.

Uses of Trigaine Solution

Trigaine Solution is used in the treatment of Alopecia (Hair loss). The detailed uses of Trigaine Solution are as follows:

  • Promotes Hair Growth: Trigaine Solution stimulates dormant hair follicles and encourages new hair formation.
  • Treats Baldness: Trigaine Solution is especially effective in the early stages of hair thinning.

Key Benefits

Trigaine Solution contains Azelaic acid, Minoxidil and Tretinoin used to treat hair loss. Azelaic acid is a naturally occurring acid that blocks the action of a 5-alpha-reductase enzyme in the body that converts testosterone (male hormone) into dihydrotestosterone which causes hair loss. Thereby, it reduces dihydrotestosterone levels and slows down hair loss. Minoxidil is a vasodilator that widens the blood vessels and improves blood circulation to the hair follicles. Thus, it prevents hair loss and stimulates hair growth. Tretinoin is a form of vitamin A that promotes hair follicle growth on the scalp.

Side effects of Trigaine Solution 60 ml
  • Stop taking the medication you suspect for causing a burning sensation and talk to your doctor about other treatment options.
  • Use creams or ointments with corticosteroids on the affected area to help reduce swelling and itching.
  • Stay out of the sun and avoid extreme temperatures, as they can make the burning sensation worse.
  • Applying a cool compress to the area can help soothe it temporarily.
  • Drink lots of fluids or water to keep your skin hydrated.
  • Avoid harsh soaps, strong chemicals, hot water, and tight clothing that can irritate your skin.
  • Eat foods that are high in antioxidants and omega-3 to help keep your skin healthy.
Here are the steps to manage medication-triggered Burning Or Stinging:
  • If you experience burning or stinging sensations and suspect that they may be related to medication, consult a doctor or healthcare expert to determine the cause and best course of treatment.
  • Avoid harsh products, extreme temperatures, and other potential irritants that may exacerbate burning or stinging.
  • Your healthcare professional may recommend applying a soothing or protective agent, such as a cream, gel, or ointment, to help alleviate burning or stinging.
  • Follow your healthcare professional's advice on how to care for the affected area, as gentle cleaning and care instructions may vary depending on the location and severity of the burning or stinging.
  • Schedule follow-up appointments with your doctor to monitor your symptoms and adjust your treatment plan as needed. If the burning or irritation persists or worsens, seek medical attention.

Directions for Use

  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
  • Check the label for directions before using Trigaine Solution. Aim the spray pump towards the required areas of the scalp and pump it once. Then, spread the solution with your fingertips.
  • Avoid breathing in the spray mist and wash your hands thoroughly after application.

How Trigaine Solution Works

Trigaine Solution is a combination of three drugs: Azelaic acid, Minoxidil (vasodilator), and Tretinoin (a form of vitamin A). Azelaic acid is a naturally occurring acid that works by blocking a 5-alpha-reductase enzyme in the body that converts testosterone (male hormone) into dihydrotestosterone which causes hair loss. Thereby, it reduces dihydrotestosterone levels and slows down hair loss. Minoxidil widens the blood vessels and improves blood circulation to the hair follicles. Thus, it prevents hair loss and stimulates hair growth. Tretinoin is a form of vitamin A that promotes hair follicle growth on the scalp.
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Alcohol

Caution

The interaction of alcohol with Trigaine Solution is unknown. Please discuss with your doctor if you have any concerns regarding this.

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Pregnancy

Caution

Please consult a doctor if you are pregnant. Trigaine Solution is not recommended for pregnant women unless suggested by a doctor.

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Breast Feeding

Caution

Please consult a doctor if you are breastfeeding.

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Driving

Safe if suggested

Trigaine Solution usually does not affect your ability to drive or operate machinery.

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Liver

Safe if suggested

If you have any concerns regarding the use of Trigaine Solution in patients with liver problems, please consult a doctor.

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Kidney

Safe if suggested

If you have any concerns regarding the use of Trigaine Solution in patients with kidney problems, please consult a doctor.

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Children

Unsafe

Trigaine Solution is not recommended for children below 18 years as the safety and effectiveness were not established.

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Heart

Caution

Please inform your doctor if you have a history of heart disease before using Trigaine Solution. Your doctor will recommend it only if the benefits outweigh the risks.

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Geriatrics

Consult your doctor

Limited data is available regarding the use of Trigaine Solution in elderly patients. If you have any concerns about the usage of Trigaine Solution in geriatrics, please consult your doctor.

What if I have taken an overdose of Trigaine Solution

Though overdose is unlikely due to low systemic absorption, it is advised to avoid exceeding the recommended dose. Seek immediate medical attention if you experience symptoms of overdose like dizziness, drowsiness, flushing, and fainting.

Diet & Lifestyle Advise

  • Avoid overusing styling tools like blow dryers, curling rods, and chemical dying, which can cause loss of natural hair oils and cause hair fall.
  • Regular oiling helps in the blood circulation of the scalp and nourishes the roots.
  • Wash your hair three times a week with a good shampoo and conditioner to reduce hair fall.
  • Practice yoga and meditation to control your stress.
  • Get your regular medical examinations done to keep a check on your hormonal profile and nutritional deficiencies that cause hair fall.

Have a query?

How Soon It Starts Working

The time required for Trigaine Solution to start to work: The time required for Trigaine Solution to show its action is unknown. The time for which the effects of Trigaine Solution last: The duration of action for Trigaine Solution is clinically unknown.

Storage

• Store in a cool and dry place away from sunlight. • Keep Trigaine Solution out of reach and sight of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if you forget to take Trigaine Solution

If you miss a dose of Trigaine Solution, use it as soon as you remember. If it is almost time for the next dose, skip the missed dose and continue with the regular dosing schedule. Do not use a double dose to make up for the missed dose.

Drug Warnings

If you are allergic to Trigaine Solution or any other medicines, please tell your doctor. Trigaine Solution is not recommended for children below 18 years of age. If you are pregnant or breastfeeding, please consult a doctor before using Trigaine Solution. You are recommended to avoid using Trigaine Solution if your scalp is irritated, infected, painful, inflamed, or red. Keep the Trigaine Solution container away from high heat or open flame as it may explode if it gets too hot. Avoid contact of Trigaine Solution with eyes. If it comes in contact with eyes accidentally, rinse with large amounts of cool tap water. If you experience unwanted facial hair growth, scalp redness or irritation, swelling in hands and legs, avoid using Trigaine Solution and consult a doctor.

Drug-Drug Interactions

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Drug-Drug Interaction: Inform your doctor if you use any other products on the scalp.

 

Drug-Food Interaction: No interactions found.

Drug-Disease Interaction: If you have sudden or patchy hair loss, eczema (itchy, swelling of the skin) or any other skin condition, inform your doctor before taking Trigaine Solution.

No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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FAQs

Trigaine Solution contains Azelaic acid, Minoxidil, and Tretinoin. Azelaic acid is a naturally occurring acid that works by blocking the action of a 5-alpha-reductase enzyme in the body that converts testosterone (male hormone) into dihydrotestosterone that causes hair loss. Thereby, it reduces dihydrotestosterone levels and slows down hair loss. Minoxidil works by widening the blood vessels and improves blood circulation to the hair follicles. Thus, it prevents hair loss and stimulates hair growth. Tretinoin is a form of vitamin A that promotes hair follicle growth on the scalp.
You are recommended to use Trigaine Solution as long as suggested by a doctor. However, if there is no hair regrowth after using Trigaine Solution for 4 months, please consult a doctor.
It is recommended to consult a doctor before using Trigaine Solution for treating patchy hair loss. Trigaine Solution is generally used to treat hereditary hair loss.
New hair may be colorless, soft, and barely visible. But with further treatment, new hair may have the same color and thickness as existing hair. However, if you have concerns regarding this, please discuss them with a doctor.
You are not recommended to use Trigaine Solution if the skin on your scalp is infected as it may worsen the condition. However, inform your doctor if you have any infection on your scalp skin before using Trigaine Solution.
It is not required to wash your hair daily after applying Trigaine Solution. However, it is better to wash it with shampoo daily. But, make sure your hair is dry and keep at least 4 hours gap before washing hair with shampoo.
Use of Trigaine Solution is not recommended for beard growth. Trigaine Solution is only suggested for hair loss and thinning of the hairs on the scalp.
Taking Trigaine Solution more than suggested will not make it more effective. Instead, it may lead to negative consequences for hair and worsen hair loss conditions as excessive medication gets absorbed into the scalp.
You will know Trigaine Solution is working by noticing improvements in your hair issues, such as a gradual decrease in hair fall, an increase in hair density, and the appearance of new hair growth.
Store Trigaine Solution in its original container, below 25°C, cool, dry, and out of sunlight. Keep it out of the reach of children. Regularly check the expiration date. To dispose of the product, remove the label, place it in a plastic bag, and throw it away in household trash. Never flush it down the toilet or sink.
The common side effects of Trigaine Solution may include headaches, itching, or irritation at the site of the application. Most of these side effects of Trigaine Solution do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
The use of Trigaine Solution is to treat hair loss conditions, promote hair growth, and improve hair density by dilating blood vessels and improving blood circulation to the hair follicles, which promotes hair follicle growth on the scalp.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. Drugs.com Clinical Review Team. Azelaic Acid Topical Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026] Check here
  2. Drugs.com Clinical Review Team. Minoxidil Topical Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026] Check here
  3. U.S. Food and Drug Administration (FDA). 019501Orig1S029Lbl [FDA Prescribing Information]. Silver Spring, MD: FDA; 2024. [Accessed on 02 Jun. 2026] Check here
  4. Drugs.com Clinical Review Team. Tretinoin Topical Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026] Check here
  5. ScienceDirect ScienceDirect. [Accessed on 29 Mar. 2019] Check here
  6. Tretinoin Tretinoin. 1997. [Accessed on 03 Apr. 2019] Check here
  7. Bazzano GS, Terezakis N, Galen W. Topical tretinoin for hair growth promotion. [Updated on Oct 1986] [Accessed on August 2022]Check here

Country of origin

INDIA

Manufacturer/Marketer address

608, Siddhartha Building- 96, Nehru Place, New Delhi-110019
Other Info - TRI0076

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