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Zacobal-Forte Tablet is a combination medicine used in the treatment of neuropathic pain, diabetic neuropathy and nutritional deficiencies. This medicine works by altering the nerve signals that cause pain and thereby protects nerve fibres. It helps provide a protective effect on the nerve tissues and the brain. You may experience common side effects like nausea, vomiting, diarrhoea, and stomach upset.

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Written By Dr. Lakshmithulasi Yarragunta , PharmD (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Manufacturer/Marketer :

Fenesta Healthcare LLP

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Zacobal-Forte Tablet

Zacobal-Forte Tablet is a dietary supplement used to support nerve health and help manage nerve pain, particularly in people with diabetic neuropathy, while also helping to correct certain nutritional deficiencies. Its active ingredients work together to replenish essential nutrients, support normal nerve function, and may help relieve symptoms such as burning, tingling, and numbness. However, the response to treatment varies from person to person, and your doctor will assess whether it is benefiting you.

For the best results, take Zacobal-Forte Tablet exactly as suggested. It can be taken with or without food, although taking it with a meal may help reduce stomach discomfort. Following a healthy lifestyle, including a balanced diet, regular physical activity, and good blood sugar control if you have diabetes, can help support nerve health alongside treatment.

Most people tolerate Zacobal-Forte Tablet well, but mild side effects such as nausea or stomach discomfort may occur. Stop taking the medicine and seek medical advice immediately if you develop symptoms of a severe allergic reaction, such as a rash, swelling of the face, lips, tongue, or throat, or difficulty breathing.

Do not take Zacobal-Forte Tablet if you have hypercalcaemia (high calcium levels in your blood) unless advised by your doctor. Tell your doctor before starting this medicine if you have kidney disease, a history of kidney stones, or any other long-term medical condition.

Alcohol and smoking may reduce the effectiveness of some of the vitamin components of this supplement. If you are pregnant, planning to become pregnant, breastfeeding, or taking medicines for diabetes or thyroid disorders, tell your doctor before using Zacobal-Forte Tablet to make sure it is suitable for you.

Uses of Zacobal-Forte Tablet

Zacobal-Forte Tablet may be used to help manage the following conditions:

  • Diabetic neuropathy: Helps protect damaged nerves, relieving symptoms like burning pain, numbness, and shooting sensations in the hands and feet.
  • Nutritional deficiencies: Replenishes essential vitamins and antioxidants that your body needs to maintain healthy nerve and cellular function.
  • General nerve support: Aids in the structural maintenance of the nervous system by supporting the rebuilding of protective nerve layers.
  • Bone health: Provides a necessary form of Vitamin D to improve calcium absorption, which supports bone density and strength.

Key Benefits

When taken as suggested, Zacobal-Forte Tablet may provide the following benefits:

  • Helps Relieve Nerve Pain: Alpha lipoic acid and B vitamins work together to help reduce symptoms of nerve damage, such as burning, tingling, and numbness, making everyday activities more comfortable.
  • Supports Healthy Nerve Function: Mecobalamin, pyridoxine, and folic acid help maintain healthy nerves, support nerve repair, and promote normal nerve signal transmission.
  • Helps Correct Nutritional Deficiencies: Replenishing essential vitamins may improve overall well-being and help reduce fatigue caused by vitamin deficiencies.
  • Supports Bone and Muscle Health: Vitamin D3 helps your body absorb calcium, supporting healthy bones, muscle function, and physical stability.

Directions for Use

  • Zacobal-Forte Tablet can be taken with or without food as advised by the doctor.
  • Take Zacobal-Forte Tablet once daily, or as recommended by your doctor, ideally at the same time each day for consistent results.
  • Swallow Zacobal-Forte Tablet as a whole with a glass of water.
  • Do not crush, chew, or break it.

How Zacobal-Forte Tablet Works

Zacobal-Forte Tablet contains a combination of active ingredients that work together to support nerve health and correct nutritional deficiencies. Alpha lipoic acid acts as an antioxidant, helping to reduce oxidative stress that can damage nerves and may help relieve symptoms such as burning, tingling, and nerve pain associated with diabetic neuropathy. Mecobalamin, an active form of vitamin B12, supports the formation and maintenance of myelin, the protective covering around nerves, helping them transmit signals normally. Pyridoxine (vitamin B6) helps produce neurotransmitters, which are chemical messengers that allow nerve cells to communicate effectively. Folic acid (vitamin B9) works with vitamin B12 to support healthy red blood cell production, DNA synthesis, and normal cell repair. Vitamin D3 helps the body absorb calcium and phosphorus, supporting healthy bones, muscle function, and normal immune function. Together, these ingredients help maintain healthy nerve function and address nutritional deficiencies that may contribute to nerve-related symptoms.
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Alcohol

Caution

It is advised to limit/avoid alcohol intake to ensure maximum absorption of nutrients.

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Pregnancy

Consult your doctor

Consult your doctor before taking Zacobal-Forte Tablet , your doctor will decide whether Zacobal-Forte Tablet can be taken by pregnant women or not.

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Breast Feeding

Consult your doctor

Consult your doctor before taking Zacobal-Forte Tablet , your doctor will decide whether Zacobal-Forte Tablet can be taken by breastfeeding mothers or not.

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Driving

Caution

It is unknown if Zacobal-Forte Tablet affects your ability to drive. Do not drive or operate machinery unless you are alert.

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Liver

Consult your doctor

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Consult your doctor

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

Zacobal-Forte Tablet should not be given to children as paediatric safety and efficacy have not been established.

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Heart

Safe if suggested

Zacobal-Forte Tablet is usually safe for individuals with heart problems when taken in the recommended dose. However, consult your doctor if you have any concerns or underlying heart issues.

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Geriatrics

Consult your doctor

Zacobal-Forte Tablet should be given to elderly patients only if recommended by a doctor. If you have any concerns, please consult your doctor.

What if I have taken an overdose of Zacobal-Forte Tablet

If you take more than the suggested amount and experience severe symptoms, seek immediate emergency medical care.

Diet & Lifestyle Advise

  • Eat a Balanced Diet: Eat a healthy, balanced diet that includes whole grains, fruits, vegetables, lean protein, and foods rich in B vitamins to help support nerve health and overall well-being.
  • Manage Blood Sugar: If you have diabetes, keep your blood sugar levels within the target range recommended by your doctor, as good glucose control can help reduce the risk of further nerve damage.
  • Stay Physically Active: Regular low-impact activities, such as walking, swimming, or stretching, can help improve circulation, maintain muscle strength, and support overall mobility.
  • Limit Alcohol: Excessive alcohol consumption may interfere with the absorption and use of B vitamins and can worsen nerve damage. Limiting alcohol may help support healthy nerve function.
  • Take Care of Your Feet: If you have diabetes or reduced sensation in your feet, inspect them daily for cuts, blisters, or other injuries, and wear comfortable, well-fitting footwear to help prevent complications.
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Have a query?

How Soon It Starts Working

The time required for Zacobal-Forte Tablet to start to work: The time required for Zacobal-Forte Tablet to show its action is unknown. 

The time for which the effects of Zacobal-Forte Tablet last: The duration of action for Zacobal-Forte Tablet is clinically unknown.

Storage

•Store Zacobal-Forte Tablet at room temperature, ideally between 15°C and 30°C (59°F to 86°F), in a dry place. •Keep the medicine in its original container, tightly closed, to protect it from moisture and direct light.

What if you forget to take Zacobal-Forte Tablet

If you miss a dose, take it as soon as you remember. However, if it is nearly time for your next scheduled dose, skip the missed one and return to your regular dosing schedule. Do not take a double dose to make up for a missed one.

Drug Warnings

  • Follow the Instructions for Your Dosage Form: Different formulations may have different administration instructions. Follow the directions provided with your suggested product or ask your doctor or pharmacist if you are unsure how to take it.
  • Tell Your Doctor About All Medicines and Supplements: Inform your doctor or pharmacist about all suggested medicines, over-the-counter medicines, vitamins, herbal products, and supplements you use before starting Zacobal-Forte Tablet .
  • Take Long-term Treatment Only as Recommended: Do not exceed the suggested dose or duration. Long-term use of high doses of pyridoxine (vitamin B6) may itself cause nerve damage (peripheral neuropathy).
  • Attend Regular Follow-up Appointments: Your doctor may monitor your progress and determine whether continued treatment is appropriate based on your symptoms and underlying condition.
  • Support Your Nerve Health: Eating a balanced diet, limiting alcohol, staying physically active, and keeping blood sugar well controlled if you have diabetes may help support healthy nerve function.

verifiedApollotooltip
  • Diabetes Medicines: Alpha lipoic acid may enhance the blood sugar-lowering effects of insulin and other diabetes medicines. Your doctor may monitor your blood sugar levels and adjust your treatment if needed.
  • Thyroid Medicines: Alpha lipoic acid may reduce the effectiveness of thyroid hormone medicines, such as levothyroxine, if taken at the same time. Your doctor or pharmacist can advise you on how to take these medicines.
  • Anti-seizure Medicines: Medicines such as phenytoin may reduce folic acid levels in the body, which could decrease the effectiveness of the folic acid component of Zacobal-Forte Tablet .
  • Other Medicines and Supplements: Tell your doctor or pharmacist about all suggested medicines, over-the-counter medicines, vitamins, herbal products, and supplements you are taking before starting Zacobal-Forte Tablet .

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verifiedApollotooltip
  • Alcohol: Regular or excessive alcohol consumption may reduce the absorption and effectiveness of mecobalamin and other B vitamins, potentially reducing the benefits of Zacobal-Forte Tablet .

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[NUTRITIONAL SUPPLEMENT]

FAQs

Zacobal-Forte Tablet is primarily used to treat nerve damage and manage nutritional deficiency.
Zacobal-Forte Tablet is a combination of five drugs: Alpha-lipoic acid, folic acid, mecobalamin, pyridoxine and vitamin D. When you lack these vitamins in your body, which cannot be recovered even with food sources, Zacobal-Forte Tablet helps replenish these deficient levels. Collectively, Zacobal-Forte Tablet treats nutritional deficiencies.
To treat your condition effectually, continue taking Zacobal-Forte Tablet for as long as recommended. Do not be reluctant to speak with your doctor if you feel any difficulty while taking Zacobal-Forte Tablet .
Pyridoxine in Zacobal-Forte Tablet may interfere with laboratory tests like urine tests for urobilinogen. Please make sure your doctor and the laboratory staff know that you take Zacobal-Forte Tablet before undergoing blood and urine examinations.
Zacobal-Forte Tablet may cause side effects such as nausea, headache and vomiting. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
Yes, Zacobal-Forte Tablet is typically taken daily to manage nerve health and resolve nutrient deficiencies, but you should always follow the specific schedule suggested by your doctor.
You can take Zacobal-Forte Tablet with or without food. However, taking it with a meal is often recommended if you have a sensitive stomach, as this can help prevent minor stomach irritation. Talk to your doctor or pharmacist if you experience persistent nausea.
If you are pregnant or breastfeeding, you should consult your doctor before starting Zacobal-Forte Tablet to ensure that the vitamin levels are appropriate and safe for you and your baby.
Mild diarrhoea can occasionally occur when starting this supplement and often resolves on its own. Ensure you stay hydrated, but if the diarrhoea becomes severe or persists for several days, talk to your doctor or pharmacist.
If you have kidney disease or a history of kidney stones, you must use caution because Zacobal-Forte Tablet contains Vitamin D3, which affects calcium levels. Talk to your doctor to determine if this supplement is safe for your condition.
It is best to take Zacobal-Forte Tablet with water. Coffee and tea contain compounds that can interfere with the absorption of certain vitamins and minerals. If you enjoy these beverages, try to drink them at least an hour before or after taking your supplement.
Take the missed dose as soon as you remember. If it is almost time for your next scheduled dose, skip the missed dose and continue with your regular routine. Do not double the dose to make up for a missed one.

Disclaimer

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Country of origin

India
Other Info - ZAC0072
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