AMLODIPINE+HYDROCHLOROTHIAZIDE+OLMESARTAN is an 'anti-hypertensives' medication primarily used for lowering high blood pressure (hypertension) by removing extra fluid (electrolytes) from the body. High blood pressure is a chronic condition in which the blood's force against the artery wall is high. As a result, it increases the risk of heart-related diseases like heart attack, heart failure, stroke, irregular heartbeat and other complications.
AMLODIPINE+HYDROCHLOROTHIAZIDE+OLMESARTAN is a combination of three medicines: Amlodipine, Hydrochlorothiazide and Olmesartan. Amlodipine is a calcium channel blocker that dilates (widens) blood vessels and increases blood flow. Altogether, it helps to lower high blood pressure, chest pain (angina) and other conditions caused by coronary artery disease. Hydrochlorothiazide is a diuretic or water pill that works by removing extra water/fluid and certain electrolyte overload from the body. Together, AMLODIPINE+HYDROCHLOROTHIAZIDE+OLMESARTAN lowers fluid overload, raises blood pressure, improves blood flow and reduces the future risk of a heart attack and stroke. On the other hand, Olmesartan is an angiotensin receptor blocker (ARB) that blocks the hormone angiotensin, thereby relaxing and widening the narrowed blood vessels. This allows the blood to flow more smoothly in the blood vessels, and the heart can pump more efficiently.
You can take AMLODIPINE+HYDROCHLOROTHIAZIDE+OLMESARTAN with food or without food with a glass of water. Do not chew, bite or break it. Your doctor will advise you on how often you take your tablets based on your medical condition. In some cases, you may experience nausea, upset stomach, dehydration, headache, diarrhoea, electrolyte imbalance, dizziness and decreased blood pressure. Most of these side effects of AMLODIPINE+HYDROCHLOROTHIAZIDE+OLMESARTAN do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.
Do not use potassium supplements or salt substitutes unless your doctor tells you. Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Do not take this AMLODIPINE+HYDROCHLOROTHIAZIDE+OLMESARTAN if you have diabetes mellitus, liver and kidney problems and low blood pressure. If you notice unexplained muscle pain, dark colour urine, tenderness or weakness, especially if you also have a fever or unexplained tiredness, immediately contact the doctor. If you have any allergy to amlodipine, hydrochlorothiazide, and olmesartan, then do not take this AMLODIPINE+HYDROCHLOROTHIAZIDE+OLMESARTAN. Try not to stop taking this medicine of your own. Let your doctor know about this, as it may cause a rise in blood pressure and increase heart disease and stroke risk. Inform your doctor if you are suffering from kidney, liver, heart disease, or diabetes.
Hypertension (high blood pressure)
AMLODIPINE+HYDROCHLOROTHIAZIDE+OLMESARTAN is a combination of three medicines: Amlodipine, Hydrochlorothiazide, and Olmesartan. Amlodipine is a calcium channel blocker that dilates (widens) blood vessels and increases blood flow. Altogether, it helps to lower high blood pressure, chest pain (angina) and other conditions caused by coronary artery disease. Hydrochlorothiazide is a diuretic or water pill that works by removing extra water/fluid and certain electrolyte overload from the body. Together, AMLODIPINE+HYDROCHLOROTHIAZIDE+OLMESARTAN lowers fluid overload, raises blood pressure, improves blood flow and reduces the future risk of a heart attack and stroke. On the other hand, Olmesartan is an angiotensin receptor blocker (ARB) that blocks the hormone angiotensin, thereby relaxing and widening the narrowed blood vessels. This allows the blood to flow more smoothly in the blood vessels, and the heart can pump more efficiently.
Do not use AMLODIPINE+HYDROCHLOROTHIAZIDE+OLMESARTAN if you are pregnant, planning for pregnancy, or unable to urinate (anuria). If you have diabetes and taking AMLODIPINE+HYDROCHLOROTHIAZIDE+OLMESARTAN with other blood pressure-lowering pills like 'aliskiren', immediately stop taking both together and consult a doctor. Besides this, it is contraindicated in low blood pressure (hypotension), cardiogenic shock (sudden stopping of blood flow to the heart) and aortic stenosis (heart valve problem). AMLODIPINE+HYDROCHLOROTHIAZIDE+OLMESARTAN may pass into breast milk, so before starting AMLODIPINE+HYDROCHLOROTHIAZIDE+OLMESARTAN, either you need to stop nursing or you should not take AMLODIPINE+HYDROCHLOROTHIAZIDE+OLMESARTAN while breastfeeding. Please inform your doctor before surgery if you are taking AMLODIPINE+HYDROCHLOROTHIAZIDE+OLMESARTAN as it needs to be stopped because it might lower the blood pressure further if taken along with local anaesthesia. Avoid potassium salt or its substitute intake while using AMLODIPINE+HYDROCHLOROTHIAZIDE+OLMESARTAN to avoid any electrolyte imbalance.
Drug-Drug interactions: AMLODIPINE+HYDROCHLOROTHIAZIDE+OLMESARTAN may interact with an antidepressant (lithium), antidiabetic medicines (metformin, insulin), drugs used to treat erectile dysfunction (sildenafil), medications used to lower cholesterol levels (simvastatin), immunosuppressants (cyclosporine), other anti-hypertensive medicines (atenolol, aliskiren, enalapril, lisinopril, ramipril, metoprolol) and pain killers (ibuprofen).
Drug-Food Interactions: Minimize high potassium foods intake and avoid over-the-counter potassium supplements, grapefruit or grapefruit juice.
Drug-Disease Interactions: AMLODIPINE+HYDROCHLOROTHIAZIDE+OLMESARTAN may interact with disease conditions, including low blood pressure, heart, and kidney, difficulty in urination, liver problems or severe dehydration, hyperkalemia (high potassium levels in the blood), and diabetes should consult the doctor before taking AMLODIPINE+HYDROCHLOROTHIAZIDE+OLMESARTAN.
You are recommended not to consume alcohol and AMLODIPINE+HYDROCHLOROTHIAZIDE+OLMESARTAN to avoid unpleasant side effects like drowsiness, dizziness and liver damage.
AMLODIPINE+HYDROCHLOROTHIAZIDE+OLMESARTAN is not recommended during pregnancy as it is a category D pregnancy drug. This medicine may cause fetal damage and can affect the unborn baby (fetus).
AMLODIPINE+HYDROCHLOROTHIAZIDE+OLMESARTAN is known to pass breast milk, but its effect on the baby is not known. So, before breastfeeding, let your doctor know about this. Either you need to stop breastfeeding for using AMLODIPINE+HYDROCHLOROTHIAZIDE+OLMESARTAN, or you need to stop takingAMLODIPINE+HYDROCHLOROTHIAZIDE+OLMESARTAN.
Drive with caution, AMLODIPINE+HYDROCHLOROTHIAZIDE+OLMESARTAN usually causes drowsiness and affects driving ability.
AMLODIPINE+HYDROCHLOROTHIAZIDE+OLMESARTAN to be taken with caution, especially if you have had a history of liver disease. Your doctor will have to change the dosage depending on your medical condition and your reaction to treatment.
AMLODIPINE+HYDROCHLOROTHIAZIDE+OLMESARTAN to be taken with caution, especially if you have had a history of kidney disease. Your doctor will have to change the dosage depending on your medical condition and your reaction to treatment.
Efficacy and safety of AMLODIPINE+HYDROCHLOROTHIAZIDE+OLMESARTAN have not been established in children. If prescribed, it should be strictly under medical supervision and only if the benefits outweigh the harms.
Hypertension: The blood exerts increased pressure on the walls of blood vessels leading to hypertension. High blood pressure is expressed as systolic/diastolic pressure. Systolic pressure is the pressure in the arteries when the heart beats or pumps out blood. Diastolic pressure is the pressure in the arteries between the heartbeats. Blood pressure is measured in millimetres of mercury (mmHg) by a blood pressure monitor called a sphygmomanometer. Some of the symptoms are headache, dizziness, nosebleeds, altered vision, chest pain, weakness, and shortness of breath. However, most of the time, the signs and symptoms of hypertension are none.