Inform your doctor if you develop persistent diarrhoea or vomiting, as it may affect the effectiveness of ATAZANAVIR+RITONAVIR. ATAZANAVIR+RITONAVIR may cause pancreatitis, so inform your doctor if you develop symptoms such as nausea (feeling sick), vomiting, or stomach pain. ATAZANAVIR+RITONAVIR may lead to opportunistic infections (infections that occur frequently or severely in patients with weak immune systems), so inform your doctor immediately if you experience symptoms of infection such as muscle weakness, weakness beginning in the hands and feet that progress towards the trunk, palpitations (pounding heartbeat), and tremors. ATAZANAVIR+RITONAVIR may destroy bone leading to symptoms such as joint stiffness or pain. It may also cause muscle pain, tenderness, or weakness. ATAZANAVIR+RITONAVIR may also cause dizziness and abnormal heartbeat. Inform your doctor immediately if you notice any significant changes in the electrocardiogram (ECG).

Drug-Drug Interactions: You should not take ATAZANAVIR+RITONAVIR with the following medications: anti-allergy medicines (astemizole and terfenadine), medicines used to correct heartbeats (amiodarone, bepridil, dronedarone, flecainide, propafenone, and quinidine), medicines used to treat migraine (dihydroergotamine and ergotamine), medicine used to stop excessive bleeding after childbirth or abortion (ergonovine and methylergonovine), medicines used to relieve anxiety (diazepam, estazolam, flurazepam, triazolam, and midazolam), antipsychotic drugs (clozapine, pimozide, and quetiapine), antidepressants (lurasidone and Hypericum perforatum), medicine used to treat chest pain (ranolazine), medicine used to treat pain (pethidine, piroxicam, buprenorphine, and propoxyphene), medicine used to treat stomach problems (cisapride), antiinfective (rifabutin), antifungal (voriconazole), medicines used to treat high cholesterol (atorvastatin, lomitapide, and rosuvastatin), anticancer agents (neratinib and irinotecan), medicine used to treat enlarged prostate (alfuzosin), antibacterial (fusidic acid), medicines used to treat erectile dysfunction (sildenafil, avanafil, vardenafil, and tadalafil), medicine used to treat gout (colchicine), antiasthma (salmeterol), anticoagulant (warfarin), medicines used to lower blood pressure or correct heart rhythm (amiodarone, diltiazem, systemic lidocaine, and verapamil), medicine used to treat heart disease (digoxin), oral contraceptives (ethinyl estradiol), and medicines that suppress immune system (cyclosporin, tacrolimus, and sirolimus).

Drug-Food Interactions: No interactions found.

Drug-Disease Interactions: ATAZANAVIR+RITONAVIR should not be used in patients with liver disease, hepatitis B or C (liver infections), hemophilia (bleeding disorder), erectile dysfunction, diabetes, gall stones, and kidney disease.

• Eat a healthy and balanced diet. Eat vitamin and nutrient-rich food such as dark-green, yellow, orange, and red vegetables and fruit as it helps to boost your immune system. Option for lean protein and whole grains.
• Avoid eating raw meat and eggs. Consume properly boiled and cooked meat, poultry, or seafood.
• Eat bland and low-fat foods and avoid spicy or oily foods if you experience nausea or vomiting.
• Try to reduce emotional and physical stress by spending time with family or whatever makes you happy.
• Drink more fluids and avoid alcoholic beverages to prevent dehydration.  
• Wash your hands properly before and after eating.
• Make sure you sleep at least 8 hours a day.

• ATAZANAVIR+RITONAVIR may still develop infections or other illnesses associated with HIV infection or AIDS. So, people taking ATAZANAVIR+RITONAVIR should be carefully monitored throughout the treatment.
• You can still infect other people while taking ATAZANAVIR+RITONAVIR. So, use necessary precautions to avoid infecting others.
• ATAZANAVIR+RITONAVIR may cause abnormal liver function tests. So, regular monitoring of liver function is necessary while taking this medicine.