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About PARACETAMOL+PHENYLEPHRINE HYDROCHLORIDE+CHLORPHENIRAMINE MALEATE

CHLORPHENIRAMINE MALEATE+PARACETAMOL+PHENYLEPHRINE HYDROCHLORIDE belongs to the class of medication called 'cough and cold medications' primarily used to treat symptoms of the common cold and allergies like sneezing, runny/stuffy nose, fever, headache, body pains, congestion, or watery eyes. The common cold is a respiratory illness affecting the nose and throat. It is mostly caused by viruses known as 'rhinovirus'. The virus enters the body through the nose, mouth, or eyes and spreads easily through droplets in the air when the person who is sick sneezes, coughs, or talks.

CHLORPHENIRAMINE MALEATE+PARACETAMOL+PHENYLEPHRINE HYDROCHLORIDE is a combination of three drugs, namely: Paracetamol (mild analgesic and antipyretic), Phenylephrine hydrochloride (decongestant), and Chlorpheniramine maleate (antihistamine/antiallergic). Paracetamol works by inhibiting the production of certain chemical messengers in the brain known as prostaglandins responsible for pain and fever. Phenylephrine hydrochloride works by shrinking the blood vessels in the nasal passage. Thereby providing relief from congestion and decreasing excess mucus production. Chlorpheniramine maleate works by blocking the action of histamine, a substance responsible for causing allergic reactions. It helps to provide relief from symptoms of allergy.

Take CHLORPHENIRAMINE MALEATE+PARACETAMOL+PHENYLEPHRINE HYDROCHLORIDE as prescribed. Your doctor will recommend how often you need to take CHLORPHENIRAMINE MALEATE+PARACETAMOL+PHENYLEPHRINE HYDROCHLORIDE based on your medical condition. Some people may experience drowsiness, nervousness, headache, dizziness, insomnia (difficulty falling or staying asleep), blurred vision, constipation, and dry mouth. Most of these side effects of CHLORPHENIRAMINE MALEATE+PARACETAMOL+PHENYLEPHRINE HYDROCHLORIDE do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to CHLORPHENIRAMINE MALEATE+PARACETAMOL+PHENYLEPHRINE HYDROCHLORIDE or any other medicines, please tell your doctor. If you are pregnant, it is advised to inform your doctor before using CHLORPHENIRAMINE MALEATE+PARACETAMOL+PHENYLEPHRINE HYDROCHLORIDE. Do not use CHLORPHENIRAMINE MALEATE+PARACETAMOL+PHENYLEPHRINE HYDROCHLORIDE if you are breastfeeding without a doctor’s advice, as it may be excreted in breast milk and cause harm to the baby. CHLORPHENIRAMINE MALEATE+PARACETAMOL+PHENYLEPHRINE HYDROCHLORIDE is not recommended for children below 4 years. Please do not take more than the prescribed dose of CHLORPHENIRAMINE MALEATE+PARACETAMOL+PHENYLEPHRINE HYDROCHLORIDE as it may cause liver damage. 

Uses of PARACETAMOL+PHENYLEPHRINE HYDROCHLORIDE+CHLORPHENIRAMINE MALEATE

Common cold, Allergies

Medicinal Benefits

CHLORPHENIRAMINE MALEATE+PARACETAMOL+PHENYLEPHRINE HYDROCHLORIDE contains Paracetamol, Phenylephrine hydrochloride, and Chlorpheniramine maleate. Paracetamol is a mild analgesic (relieves pain) and antipyretic (reduces fever) that works by inhibiting the production of certain chemical messengers in the brain known as prostaglandins that are responsible for pain and fever. Phenylephrine hydrochloride is a decongestant that works by contracting and narrowing the blood vessels. Thereby, providing relief from congestion and decreasing mucus production. Chlorpheniramine maleate is an antihistamine (anti-allergic drug) that works by blocking the action of histamine, a substance responsible for causing allergic reactions. It helps to provide relief from symptoms of allergy such as sneezing, running nose, watery eyes, itching, swelling, and congestion or stiffness.

Directions for Use

Tablet/capsule: Take it with or without food as advised by the doctor. Swallow it whole with a glass of water. Do not crush, chew or break it. Oral syrup: Shake the bottle well before use. Check the label for directions and take the syrup with or without food in doses as prescribed by a doctor with the help of a measuring cup.

Storage

Store in a cool and dry place away from sunlight

Side Effects of PARACETAMOL+PHENYLEPHRINE HYDROCHLORIDE+CHLORPHENIRAMINE MALEATE

  • Drowsiness
  • Nervousness
  • Headache
  • Dizziness
  • Insomnia (difficulty in falling or staying asleep)
  • Blurred vision
  • Constipation
  • Dry mouth

In-Depth Precautions and Warning

Drug Warnings

If you are allergic to CHLORPHENIRAMINE MALEATE+PARACETAMOL+PHENYLEPHRINE HYDROCHLORIDE or any other medicines, please tell your doctor. If you are pregnant, it is advised to inform your doctor before using CHLORPHENIRAMINE MALEATE+PARACETAMOL+PHENYLEPHRINE HYDROCHLORIDE. Do not use CHLORPHENIRAMINE MALEATE+PARACETAMOL+PHENYLEPHRINE HYDROCHLORIDE if you are breastfeeding without a doctor’s advice as it may be excreted in breast milk and cause harm to the baby. CHLORPHENIRAMINE MALEATE+PARACETAMOL+PHENYLEPHRINE HYDROCHLORIDE is not recommended for children below 4 years. Please do not take more than the prescribed dose of CHLORPHENIRAMINE MALEATE+PARACETAMOL+PHENYLEPHRINE HYDROCHLORIDE as it may cause liver damage.  If you have high blood pressure, diabetes, glaucoma, hyperthyroidism (overactive thyroid), chronic bronchitis, asthma, chronic obstructive pulmonary disease (COPD), blockage in the stomach or intestines, enlarged prostate gland, pheochromocytoma (tumour in the adrenal glands), kidney, liver, heart or urinary problems, inform your doctor before taking CHLORPHENIRAMINE MALEATE+PARACETAMOL+PHENYLEPHRINE HYDROCHLORIDE.

Drug Interactions

Drug-Drug Interaction: CHLORPHENIRAMINE MALEATE+PARACETAMOL+PHENYLEPHRINE HYDROCHLORIDE may interact with anti-allergic drugs (diphenhydramine, cetirizine), antidepressants (duloxetine, escitalopram), anticonvulsants (clonazepam), antianxiety drug (alprazolam), muscle relaxants (cyclobenzaprine), cough suppressants (dextromethorphan), bronchodilator (albuterol), sleeping agent (ramelteon), pain and fever medicines (paracetamol), pain killers (ibuprofen).

Drug-Food Interaction: Avoid intake of CHLORPHENIRAMINE MALEATE+PARACETAMOL+PHENYLEPHRINE HYDROCHLORIDE with chocolate and caffeine-containing foods such as cocoa beans and tea leaves as they may increase the risk of severity of side effects. Avoid consumption of alcohol with CHLORPHENIRAMINE MALEATE+PARACETAMOL+PHENYLEPHRINE HYDROCHLORIDE as it may increase the risk of liver damage and cause increased drowsiness, dizziness and difficulty in concentrating.

Drug-Disease Interaction: If you have high blood pressure, diabetes, glaucoma, hyperthyroidism (overactive thyroid), chronic bronchitis, asthma, chronic obstructive pulmonary disease (COPD), blockage in the stomach or intestines, enlarged prostate gland, pheochromocytoma (tumour in the adrenal glands), kidney, liver, heart or urinary problems, inform your doctor before taking CHLORPHENIRAMINE MALEATE+PARACETAMOL+PHENYLEPHRINE HYDROCHLORIDE.

Drug-Drug Interactions Checker List:

  • DIPHENHYDRAMINE
  • CETIRIZINE
  • DULOXETINE
  • ESCITALOPRAM
  • CLONAZEPAM
  • ALPRAZOLAM
  • CYCLOBENZAPRINE
  • DEXTROMETHORPHAN
  • ALBUTEROL
  • PARACETAMOL
  • IBUPROFEN
  • RAMELTEON

    • Safety Advice

    • Safety Warning

      Alcohol

      unsafe

      Avoid consumption of alcohol with CHLORPHENIRAMINE MALEATE+PARACETAMOL+PHENYLEPHRINE HYDROCHLORIDE as it may increase the risk of liver damage and cause increased drowsiness, dizziness or difficulty in concentrating. Please consult a doctor before consuming alcohol with CHLORPHENIRAMINE MALEATE+PARACETAMOL+PHENYLEPHRINE HYDROCHLORIDE.

    • Safety Warning

      Pregnancy

      caution

      The safety of CHLORPHENIRAMINE MALEATE+PARACETAMOL+PHENYLEPHRINE HYDROCHLORIDE in pregnant women is unknown. Therefore, it is given to pregnant women only if the doctor thinks benefits outweigh risks.

    • Safety Warning

      Breast Feeding

      caution

      CHLORPHENIRAMINE MALEATE+PARACETAMOL+PHENYLEPHRINE HYDROCHLORIDE may be excreted in breast milk and cause harm to the baby. Besides this, CHLORPHENIRAMINE MALEATE+PARACETAMOL+PHENYLEPHRINE HYDROCHLORIDE may also slow the milk production, so it is better to contact a doctor before a lactating mother takes it.

    • Safety Warning

      Driving

      caution

      CHLORPHENIRAMINE MALEATE+PARACETAMOL+PHENYLEPHRINE HYDROCHLORIDE may cause blurred vision or impair thinking in some people. Therefore, drive only if you are alert after taking CHLORPHENIRAMINE MALEATE+PARACETAMOL+PHENYLEPHRINE HYDROCHLORIDE.

    • Safety Warning

      Liver

      caution

      Take CHLORPHENIRAMINE MALEATE+PARACETAMOL+PHENYLEPHRINE HYDROCHLORIDE with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

    • Safety Warning

      Kidney

      caution

      Take CHLORPHENIRAMINE MALEATE+PARACETAMOL+PHENYLEPHRINE HYDROCHLORIDE with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

    • Safety Warning

      Children

      caution

      CHLORPHENIRAMINE MALEATE+PARACETAMOL+PHENYLEPHRINE HYDROCHLORIDE is not recommended for children below four years of age. However, please consult a doctor before giving CHLORPHENIRAMINE MALEATE+PARACETAMOL+PHENYLEPHRINE HYDROCHLORIDE to children.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • Wash your hands with soap and water regularly to prevent the spread of germs.
    • Eat plenty of foods rich in good bacteria like yoghurt to improve overall health.
    • Drink plenty of fluids to avoid dehydration.
    • Gargle with salt water for relief from sore throat.
    • Avoid consumption of alcohol with CHLORPHENIRAMINE MALEATE+PARACETAMOL+PHENYLEPHRINE HYDROCHLORIDE as it may cause tiredness, drowsiness, or lack of concentration.

    Special Advise

    • Do not give CHLORPHENIRAMINE MALEATE+PARACETAMOL+PHENYLEPHRINE HYDROCHLORIDE to children below 4 years of age.
    • Do not take CHLORPHENIRAMINE MALEATE+PARACETAMOL+PHENYLEPHRINE HYDROCHLORIDE for longer than 7 days in a row (for adults) and 5 days (for the children above 4 years).
    • If you have allergic skin reactions like skin redness or rash that spreads and causes blistering and peeling, immediately contact a doctor.

    Patients Concern

    Disease/Condition Glossary

    Common cold: The common cold is an infection caused by the virus, mainly known as ‘rhinoviruses’ affecting the nose and throat (upper respiratory tract). Children younger than 6 years are at the most significant risk of colds, but healthy adults can also be affected to have 2-3 colds annually. In most cases, cold symptoms are recovered within a week or ten days. However, symptoms might last longer in people who smoke or are exposed to allergens like pollutants, dust, etc. The symptoms of the common cold include sneezing, sore throat, cough, congestion, mild body pains, low fever, mild headache, feeling unwell, stuffy, or runny nose. In some cases, the discharge from the nose may become thicker and yellow or green, which is not an indication of bacterial infection.

    Allergies: It occurs when allergy-causing agents (allergens) attack and invades our body thereby causing the release of histamines. This chemical messenger 'histamine' causes swelling, inflammation, redness, itchiness, itchy/watery nose, and watery eyes. Allergies generally occur due to chemicals, air pollution, pet danders, dust, pollen hairs, seasonal allergies like hay fever, etc.

    FAQs

    How does CHLORPHENIRAMINE MALEATE+PARACETAMOL+PHENYLEPHRINE HYDROCHLORIDE work?

    CHLORPHENIRAMINE MALEATE+PARACETAMOL+PHENYLEPHRINE HYDROCHLORIDE contains Paracetamol, Phenylephrine hydrochloride, and Chlorpheniramine maleate. Paracetamol works by inhibiting the production of certain chemical messengers in the brain known as prostaglandins that are responsible for pain and fever. Phenylephrine hydrochloride works by contracting and narrowing the blood vessels. Thereby, providing relief from congestion and decreasing mucus production. Chlorpheniramine maleate works by blocking the action of histamine, a substance responsible for causing allergic reactions.

    Does CHLORPHENIRAMINE MALEATE+PARACETAMOL+PHENYLEPHRINE HYDROCHLORIDE also relieve pain and fever?

    CHLORPHENIRAMINE MALEATE+PARACETAMOL+PHENYLEPHRINE HYDROCHLORIDE contains paracetamol which acts as a mild pain killer (analgesic) and fever reducer (antipyretic). It works by inhibiting the production of certain chemical messengers in the brain known as prostaglandins responsible for pain and fever.

    Does CHLORPHENIRAMINE MALEATE+PARACETAMOL+PHENYLEPHRINE HYDROCHLORIDE cause drowsiness?

    CHLORPHENIRAMINE MALEATE+PARACETAMOL+PHENYLEPHRINE HYDROCHLORIDE may cause drowsiness. It is not necessary for everyone taking CHLORPHENIRAMINE MALEATE+PARACETAMOL+PHENYLEPHRINE HYDROCHLORIDE to experience this side effect. Therefore, avoid driving or operating heavy machinery if you feel drowsy after taking CHLORPHENIRAMINE MALEATE+PARACETAMOL+PHENYLEPHRINE HYDROCHLORIDE.

    Can I take CHLORPHENIRAMINE MALEATE+PARACETAMOL+PHENYLEPHRINE HYDROCHLORIDE with Cetirizine (an antiallergic medicine)?

    You are not recommended to take CHLORPHENIRAMINE MALEATE+PARACETAMOL+PHENYLEPHRINE HYDROCHLORIDE with Cetirizine as co-administration of these two medicines may increase sedation and can cause drowsiness, dizziness and difficulty in concentrating. However, please consult a doctor before taking CHLORPHENIRAMINE MALEATE+PARACETAMOL+PHENYLEPHRINE HYDROCHLORIDE with other medicines.

    Can I stop taking CHLORPHENIRAMINE MALEATE+PARACETAMOL+PHENYLEPHRINE HYDROCHLORIDE on my own?

    You are not recommended to stop taking CHLORPHENIRAMINE MALEATE+PARACETAMOL+PHENYLEPHRINE HYDROCHLORIDE without consulting your doctor as it may worsen the condition or cause recurring symptoms. Therefore, take CHLORPHENIRAMINE MALEATE+PARACETAMOL+PHENYLEPHRINE HYDROCHLORIDE for as long as your doctor has prescribed it, and if you experience any difficulty while taking CHLORPHENIRAMINE MALEATE+PARACETAMOL+PHENYLEPHRINE HYDROCHLORIDE, please consult your doctor.

    In which condition should I avoid taking CHLORPHENIRAMINE MALEATE+PARACETAMOL+PHENYLEPHRINE HYDROCHLORIDE?

    Do not use CHLORPHENIRAMINE MALEATE+PARACETAMOL+PHENYLEPHRINE HYDROCHLORIDE if you have used an MAO inhibitor in the past 14 days, like isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, or tranylcypromine. Tell your doctor before taking CHLORPHENIRAMINE MALEATE+PARACETAMOL+PHENYLEPHRINE HYDROCHLORIDE if you have nausea, stomach pain, itchy skin, loss of appetite, dark urine, clay-coloured stools, or jaundice (yellowing of your skin or eyes). In rare cases, paracetamol present in CHLORPHENIRAMINE MALEATE+PARACETAMOL+PHENYLEPHRINE HYDROCHLORIDE may cause a severe skin allergic reaction. So, if you observe any skin blisters or redness or rash, stop taking CHLORPHENIRAMINE MALEATE+PARACETAMOL+PHENYLEPHRINE HYDROCHLORIDE and contact your doctor.

    Available Medicines for

    CHLORPHENIRAMINE MALEATE+PARACETAMOL+PHENYLEPHRINE HYDROCHLORIDE