LAMIVUDINE+ZIDOVUDINE belongs to the class of medicines called 'anti-retroviral agents', used for the treatment of immunodeficiency virus (HIV) infection. HIV (human immunodeficiency virus) is a virus that attacks the body’s immune system. If HIV is not treated, it can lead to AIDS (acquired immunodeficiency syndrome). This medicine is not a cure for HIV. It only prevents the virus from multiplying in your body.
LAMIVUDINE+ZIDOVUDINE contains lamivudine and zidovudine. LAMIVUDINE+ZIDOVUDINE works by preventing HIV (virus) from multiplying, thereby reducing the amount of virus in your body. They also increase the CD4 cell (white blood cells that protect against infection) count in your blood.
Take LAMIVUDINE+ZIDOVUDINE as advised by your doctor. LAMIVUDINE+ZIDOVUDINE may cause common side effects like nausea, diarrhoea, headache, fatigue, cough, a feeling of discomfort, and nasal congestion (stuffy nose). Most of these side effects gradually resolve over time and do not require medical attention. However, if these side effects persist or worsen, please consult your doctor immediately.
Inform your doctor if you are allergic to any of the components in LAMIVUDINE+ZIDOVUDINE. Please consult your doctor if you are pregnant, planning to conceive or breastfeeding. Let your doctor know if you have kidney, liver, or pancreatic disease. Please tell your doctor if you have a low red blood cell count (anaemia), low white blood cell count (neutropenia), osteonecrosis (death of bone tissue due to a lack of blood supply), or lactic acidosis.
Human immunodeficiency virus (HIV) infection.
LAMIVUDINE+ZIDOVUDINE contains a combination of two medicines, namely: lamivudine and zidovudine, that belong to the group of medications called anti-retroviral agents. LAMIVUDINE+ZIDOVUDINE is primarily used for the treatment of human immunodeficiency virus (HIV) infection. LAMIVUDINE+ZIDOVUDINE works by preventing HIV (virus) from multiplying, thereby reducing the amount of virus in your body. They also increase the CD4 cell (white blood cells that protect against infection) count in your blood.
Inform your doctor if you are allergic to any of the components in LAMIVUDINE+ZIDOVUDINE. Please consult your doctor if you are pregnant, planning to conceive or breastfeeding. Let your doctor know if you have kidney, liver, pancreatic, or bone marrow suppression. Please tell your doctor if you have a low red blood cell count (anaemia), low white blood cell count (neutropenia), osteonecrosis (death of bone tissue due to a lack of blood supply), lactic acidosis, or opportunistic infections. LAMIVUDINE+ZIDOVUDINE may cause muscle disorders, especially when used for a long period. Tell your doctor if you have or have ever had any disease of the muscles or muscle weakness. If you experience muscle pain or muscle weakness, call your doctor immediately.
Drug-Drug Interaction: LAMIVUDINE+ZIDOVUDINE may interact with other antiretroviral (didanosine, efavirenz), antibiotic (atovaquone, clarithromycin, ganciclovir), anti-fungal (cotrimoxazole, fluconazole), anti-mycobacterial (rifampicin), anti-convulsants (phenobarbital, phenytoin, valproic acid), anti-histamines (ranitidine, cimetidine), cytotoxics (cladribine), opioids (methadone), uricosuric (probenecid), anti-cancer (methotrexate), anti-lipemic (atorvastatin, fenofibrate), anti-psychotic (clozapine).
Drug-Food Interaction: No interaction found/established.
Drug-Disease Interaction: Before taking LAMIVUDINE+ZIDOVUDINE, let your doctor know if you have any kidney disease, liver disease, pancreatic disease, bone marrow suppression, low red blood cell count (anaemia), low white blood cell count (neutropenia), osteonecrosis (death of bone tissue due to a lack of blood supply), lactic acidosis or muscle disorders.
LAMIVUDINE+ZIDOVUDINE with alcohol can cause unpleasant side effects. So please consult your doctor before consumption of alcohol while taking LAMIVUDINE+ZIDOVUDINE.
LAMIVUDINE+ZIDOVUDINE is not recommended for use in pregnant women unless necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
LAMIVUDINE+ZIDOVUDINE is not recommended for use in breastfeeding women unless necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may advise you to discontinue the drug or breastfeeding based on your clinical condition.
LAMIVUDINE+ZIDOVUDINE may cause dizziness or sleepiness. Don't drive or do anything requiring concentration until you know how it affects you.
LAMIVUDINE+ZIDOVUDINE should be used with caution in liver patients due to the increased risk of worsening the patient's condition. So please consult your doctor before taking LAMIVUDINE+ZIDOVUDINE.
LAMIVUDINE+ZIDOVUDINE should be used with caution in kidney patients due to the increased risk of serious side effects. So please consult your doctor before taking LAMIVUDINE+ZIDOVUDINE.
LAMIVUDINE+ZIDOVUDINE should be used with caution in Children. Your doctor may prescribe LAMIVUDINE+ZIDOVUDINE by adjusting the dose based on the height and weight of the children.
HIV (human immunodeficiency virus): HIV (human immunodeficiency virus) is a virus that attacks the body's immune system. If HIV is not treated, it can lead to AIDS (acquired immunodeficiency syndrome). There is currently no effective cure. Once people get HIV, they have it for life. But with proper medical care, HIV can be controlled. Symptoms include swollen lymph nodes, recurrent fevers, night sweats, fatigue, nausea, vomiting, diarrhoea, weight loss, skin rashes, recurrent oral or vaginal yeast infections, and pneumonia. The human immunodeficiency virus causes HIV infection. You can get HIV from contact with infected blood, semen, or vaginal fluids. Most people get the virus by having unprotected sex with someone who has HIV.