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Lignocaine+metronidazole+sucralfate

About Lignocaine+metronidazole+sucralfate

Lignocaine+metronidazole+sucralfate is a specialised rectal medication used to relieve the pain, swelling, and discomfort associated with haemorrhoids (piles) and anal fissures. It combines three active therapeutic actions to numb local pain, reduce bacterial growth, and form a physical barrier over damaged tissue to encourage healing. This product is formulated specifically for localised rectal application to target the root of the discomfort directly.

For best results, you should apply Lignocaine+metronidazole+sucralfate consistently and exactly as directed by your doctor, often after a bowel movement to ensure maximum contact with the affected tissue. This medication does not need to be taken with food, but maintaining a fibre-rich diet and drinking plenty of water during your treatment will help soften your stools and reduce strain. Consistent use as prescribed ensures the tissues have a continuous protective environment to heal.

Most patients tolerate Lignocaine+metronidazole+sucralfate very well, but you may experience mild, temporary local side effects like a brief burning sensation, itching, or redness at the application site. These symptoms usually resolve on their own within a few minutes. However, if you experience severe skin irritation, worsening rectal pain, or signs of an allergic reaction, stop using the product and consult your doctor immediately.

Do not use this medicine if you have a known history of allergy to local anaesthetics or any of the other active ingredients. Before starting Lignocaine+metronidazole+sucralfate, tell your doctor if you have severe liver damage, poor blood circulation, or active open wounds in the rectal area that are deep or bleeding excessively. Your doctor will evaluate if this medication is safe for your specific condition.

Although this medicine is applied rectally, some of the metronidazole may be absorbed into the bloodstream. Tell your healthcareprovider about all the medicines you are taking, including other rectal products. It is also best to avoid alcohol during treatment, as metronidazole may cause an unpleasant reaction in some people, including flushing, nausea, vomiting, stomach cramps, and a fast heartbeat. If you are pregnant, breastfeeding, or planning a pregnancy, talk to your doctor or pharmacist before starting this treatment to ensure it is safe for you.

Uses of Lignocaine+metronidazole+sucralfate

Lignocaine+metronidazole+sucralfate is used in the treatment of piles, fistula and anal fissure. The detailed uses of Lignocaine+metronidazole+sucralfate are as follows:
• Anal Fissures: Lignocaine+metronidazole+sucralfate helps heal small tears in the anal lining and reduces pain while passing stools.
• Hemorrhoids: Lignocaine+metronidazole+sucralfate provides relief from swelling, irritation, and discomfort.
• Post-Surgical Pain Relief: Lignocaine+metronidazole+sucralfate is used after anorectal surgeries to ease pain and promote healing.
• Treatment of fistula: Lignocaine+metronidazole+sucralfate helps in managing fistula-related symptoms like reducing irritation and ease discomfort.

Medicinal Benefits

Lignocaine+metronidazole+sucralfate is used to relieve pain, prevent infection, and promote healing of wounds and anorectal conditions such as anal fissures or post-surgical wounds. It provides symptomatic relief while supporting the natural healing process.

  • Provides Fast Pain Relief: Lignocaine numbs the affected area, helping relieve pain, burning, and discomfort.
  • Helps Prevent Infection: Metronidazole helps control bacterial growth, reducing the risk of infection in the treated area.
  • Promotes Wound Healing: Sucralfate forms a protective barrier over damaged tissues, supporting healing and protecting the wound from further irritation.
  • Reduces Discomfort During Bowel Movements: By relieving pain and protecting the affected area, it helps make bowel movements more comfortable.
  • Supports Tissue Recovery: The combined action of the ingredients helps reduce inflammation, promote tissue repair, and improve overall comfort.

Directions for Use

  • Adhere to your doctor's guidance regarding the dosage and timing of this medication for optimal effectiveness.
  • Apply a small amount of Lignocaine+metronidazole+sucralfate on the clean and dry affected area of the skin of the anus.
  • Wash your hands before and after using Lignocaine+metronidazole+sucralfate.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Lignocaine+metronidazole+sucralfate

Common Side Effects (Usually mild)

  • Mild burning or stinging immediately after application
  • Temporary local redness or itching
  • Slight dryness of the skin around the treated area


Serious Side Effects (Consult your doctor right away)

  • Severe skin rash, hives, or swelling of the face, lips, tongue, or throat
  • Sudden difficulty breathing or severe dizziness
  • orsening rectal bleeding or severe, throbbing pain that does not go away

Drug Warnings

  • Inspect the Medicine Before Use: Do not use the gel if the tube seal is broken or if the product appears discoloured, separated, or has an unusual odour.
  • Clean the Applicator After Use: Wash the applicator thoroughly with warm water and mild soap after each use to help prevent contamination.
  • For External or Rectal Use Only: Use the medicine only as directed. Do not swallow it or allow it to come into contact with your eyes, nose, or mouth.
  • Use Only for the Prescribed Duration: Do not continue using the medicine for longer than recommended, as prolonged use of local anaesthetics may increase the risk of skin sensitivity or delayed healing.
  • Wear Loose, Breathable Clothing: Avoid tight-fitting or non-breathable clothing that may trap moisture and increase irritation around the affected area.

Drug Interactions

Lignocaine+metronidazole+sucralfate may interact with certain medicines, affecting its effectiveness or increasing the risk of side effects.

  • Heart rhythm medicines: May interact with oral antiarrhythmic drugs if significant amounts of the local anaesthetic are absorbed into the bloodstream.
  • Other topical rectal products: Using other rectal creams, ointments, or suppositories at the same time may interfere with the absorption or protective barrier effect of Lignocaine+metronidazole+sucralfate.

Drug-Drug Interactions Checker List:

  • AMIODARONE
  • MEXILETINE
  • PROPRANOLOL
  • METOPROLOL
  • CIMETIDINE
  • WARFARIN
  • TOCAINIDE
  • TUBERCULOSIS VACCINE
  • DICOUMAROL
  • Safety Advice

    • Safety Warning

      Alcohol

      caution

      Interaction of Lignocaine+metronidazole+sucralfate with alcohol is unknown. Please consult a doctor before consuming alcohol while using Lignocaine+metronidazole+sucralfate.

    • Safety Warning

      Pregnancy

      caution

      Please consult a doctor if you are pregnant or planning for pregnancy. Lignocaine+metronidazole+sucralfate is given to pregnant women only if the doctor thinks the benefits outweigh the risks.

    • Safety Warning

      Breast Feeding

      caution

      It is unknown whether Lignocaine+metronidazole+sucralfate is excreted in human milk. Therefore, it is given to breastfeeding mothers only if the doctor thinks benefits are greater than risks.

    • Safety Warning

      Driving

      safe if prescribed

      Lignocaine+metronidazole+sucralfate usually does not affect your ability to drive or operate machinery.

    • Safety Warning

      Liver

      caution

      If you have any concerns regarding the use of Lignocaine+metronidazole+sucralfate in patients with liver problems, please consult a doctor.

    • Safety Warning

      Kidney

      caution

      If you have any concerns regarding the use of Lignocaine+metronidazole+sucralfate in patients with kidney problems, please consult a doctor.

    • Safety Warning

      Children

      caution

      Lignocaine+metronidazole+sucralfate should be used in children only if prescribed by a doctor.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • Increase dietary fibre: Eat more whole grains, fruits, vegetables, and beans to soften your stool and make bowel movements easier.
    • Stay hydrated: Drink at least 8 to 10 glasses of water daily to prevent constipation and reduce straining.
    • Avoid straining: Do not strain or hold your breath during bowel movements, as this increases pressure on the rectal veins.
    • Practice sitz baths: Sit in a tub of warm water for 15 to 20 minutes two to three times a day to soothe the area and improve blood flow.
    • Wear loose clothing: Choose breathable cotton underwear to prevent moisture buildup and reduce friction on the irritated tissues.

    Special Advise

    Follow the WASH regimen for anorectal diseases like piles:

    • W stands for a warm sitz bath for 10 minutes.

    • A stands for analgesic and painkiller.

    • S stands for stool softener.

    • H stands for hemorrhoidal cream. 

    Patients Concern

    Disease/Condition Glossary

    Anal Fissure: It is a small cut or tear in the lining of the anus. Sometimes, the crack may be so deep that it exposes the muscle tissue underneath. It occurs mostly when passing hard or large stools, diarrhoea or chronic constipation. The crack in the skin leads to severe pain and bleeding during and after bowel movements. Anal fissure symptoms include sharp pain in the anal region during bowel movements, itching or burning sensation in the anal region, a visible tear in the skin around the anus, streaks of blood on stools, a skin tag or small lumps or skin next to the tear.

    Piles: It occurs when anus tissue and vein become inflamed and swollen. The size of piles can vary from small to large, either found inside or outside the anus. Piles can occur due to many reasons like chronic constipation, chronic diarrhoea, pregnancy, lifting heavy weights or straining when passing a stool.

    Anal Fistula: It is an abnormal connection between the inside of the anal canal and the skin around the anus resulting from an injury or surgery. Infection or inflammation can also cause a fistula to form.

    FAQs

    Lignocaine+metronidazole+sucralfate is used in the treatment of anal fissures (small tear in the anus lining), fistula (abnormal skin opening near the anus) and piles (inflamed and swollen veins in the rectum).

    Lignocaine+metronidazole+sucralfate contains Lignocaine, Metronidazole and Sucralfate. Lignocaine decreases pain sensation by preventing pain signals transmission from nerves to the brain. Metronidazole minimizes the spread of bacterial infection around the anus skin region due to swelling and inflamed veins. Sucralfate is a protectant that works by forming a protective layer over the affected area of skin and prevents pain, irritation or burning sensation in the anus. Thereby promoting healing of anus skin and the formation of new healthy skin.

    Lignocaine+metronidazole+sucralfate may cause a burning sensation of the skin at the application site as a temporary side effect. However, if the burning sensation persists or worsens, please consult a doctor. Also, avoid using and consult a doctor if you experience increased irritation or redness.

    You are recommended to avoid foods rich in oil content and spicy foods for effective results while taking Lignocaine+metronidazole+sucralfate.

    Yes, Lignocaine+metronidazole+sucralfate provides relief from pain caused by an anal fissure. Lignocaine+metronidazole+sucralfate contains lignocaine, a local anaesthetic that decreases pain sensation by causing numbness around the affected area.

    Do not stop using Lignocaine+metronidazole+sucralfate without consulting your doctor even if you find symptomatic relief as discontinuing suddenly may worsen the condition. Therefore, complete the full course of Lignocaine+metronidazole+sucralfate as your doctor has prescribed it, and if you experience any difficulty while using Lignocaine+metronidazole+sucralfate, please consult your doctor.

    No, Lignocaine+metronidazole+sucralfate should not be used for external wounds. Please consult a doctor so that appropriate medication is prescribed to treat external wounds.

    Lignocaine+metronidazole+sucralfate is usually not recommended to use in children as safety has not been studied.

    No, using higher dosages of Lignocaine+metronidazole+sucralfate won't make it any more effective. An excessive amount of medication may result in unintended adverse effects.

    No, it is not intended to treat burns.

    No, don't stop using Lignocaine+metronidazole+sucralfate. Your symptoms may improve before the condition is completely cured, but you should complete the entire course of treatment.

    Yes, Lignocaine+metronidazole+sucralfate is a combination medicine used in the treatment of anal fissures, anal fistula, and piles (haemorrhoids) effectively.

    Your doctor will advise you how often you need to use Lignocaine+metronidazole+sucralfate based on your medical condition.

    Lignocaine+metronidazole+sucralfate is a combination of three drugs, namely: Lignocaine (local anaesthetic), Metronidazole (antibiotic) and Sucralfate (protectant).

    Use Lignocaine+metronidazole+sucralfate as prescribed by your doctor. Apply a small amount of Lignocaine+metronidazole+sucralfate on the clean and dry affected area of the skin of the anus. Lignocaine+metronidazole+sucralfate is only for external use. Avoid contact of Lignocaine+metronidazole+sucralfate with nose, mouth or eyes. In case Lignocaine+metronidazole+sucralfate comes in contact with these areas accidentally, rinse with water thoroughly. Wash your hands before and after using Lignocaine+metronidazole+sucralfate.

    Sometimes, Lignocaine+metronidazole+sucralfate may cause mild irritation, skin rash, and a tingling or burning sensation at the application site. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

    No, you should not use if you are allergic to any components present in it.

    Do not apply Lignocaine+metronidazole+sucralfate on cuts, wounds, grazes, raw or blistered skin.

    Store in a cool and dry place away from sunlight. Keep Lignocaine+metronidazole+sucralfate out of reach and sight of children.

    You should only use Lignocaine+metronidazole+sucralfate during pregnancy if your doctor specifically prescribes it after assessing the benefits and risks. Talk to your doctor before starting this medication.

    It is best to avoid alcohol while using this medicine and for at least 48 hours after completing treatment. The metronidazole component may cause an unpleasant reaction with alcohol in some people, leading to flushing, nausea, vomiting, stomach cramps, or a fast heartbeat. Alcohol may also worsen dehydration and constipation, which can aggravate piles and anal fissures.

    Lignocaine+metronidazole+sucralfate relieves pain, reduces inflammation, and helps heal damaged tissues, but it may not prevent haemorrhoids from returning if underlying causes like constipation or straining persist. Talk to your doctor about long-term dietary and lifestyle changes to manage your condition.

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