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About NEBIVOLOL+S AMLODIPINE

NEBIVOLOL+S AMLODIPINE is a combination of blood pressure-lowering medicine primarily used to treat high blood pressure and reduce the further risk of heart attack or stroke. Hypertension or high blood pressure is a chronic condition in which the blood's force against the artery wall is high. As a result, it leads to heart disease, irregular heartbeat, and other complications. NEBIVOLOL+S AMLODIPINE lowers your blood pressure and reduces the risk of having a stroke, a heart attack, other heart problems, or kidney problems in the future.

NEBIVOLOL+S AMLODIPINE is a combination of S Amlodipine (calcium channel blocker) and Nebivolol (beta-blocker). S Amlodipine acts by relaxing the blood vessels and reducing the heart's workload, and making the heart more efficient at pumping blood throughout the body. Nebivolol helps in relaxing the blood vessels by blocking the action of certain natural substances in the body.

Take NEBIVOLOL+S AMLODIPINE as prescribed by your doctor. You are advised to take NEBIVOLOL+S AMLODIPINE for as long as your doctor has prescribed it for you, depending on your medical condition.  Some people may experience headaches, feeling exhausted and swollen ankles. Most of these side effects of NEBIVOLOL+S AMLODIPINE do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

It is advisable to drink plenty of fluids while taking this medicine to overcome muscle weakness, dry mouth, and extreme thirst. Do not take grapefruit or grapefruit juices with NEBIVOLOL+S AMLODIPINE as it can increase the concentration of NEBIVOLOL+S AMLODIPINE in the blood and worsen its side effects. Please inform your doctor if you have had an allergic reaction to NEBIVOLOL+S AMLODIPINE, are pregnant, plan to get pregnant, are breastfeeding, have liver disease, kidney disease, heart failure, diabetes, a heart valve problem, or heart attack. Reducing the amount of table salt will happen.

Uses of NEBIVOLOL+S AMLODIPINE

Hypertension (high blood pressure)

Medicinal Benefits

NEBIVOLOL+S AMLODIPINE is a combination of two medicines: S Amlodipine and Nebivolol, which help lower raised blood pressure effectively. S Amlodipine, a calcium channel blocker that acts by relaxing the blood vessels. This reduces the heart's workload and makes the heart more efficient at pumping blood throughout the body. Nebivolol (beta-blocker) helps in relaxing our blood vessels by blocking the action of certain natural substances in your body. This lowers your blood pressure and reduces your risk of having a stroke, a heart attack, other heart problems, or kidney problems in the future. This medicine needs to be taken regularly to be effective. 

Directions for Use

Take NEBIVOLOL+S AMLODIPINE with or without food as advised by your doctor. Swallow it as a whole with a glass of water. Do not crush, chew, or break it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of NEBIVOLOL+S AMLODIPINE

  • Bradycardia (slow heart rate)
  • Increased blood potassium level
  • Cold extremities
  • Gastrointestinal disturbances 
  • Nausea
  • Fatigue

In-Depth Precautions and Warning

Drug Warnings

Don't stop taking NEBIVOLOL+S AMLODIPINE without talking to your doctor first. Stopping NEBIVOLOL+S AMLODIPINE abruptly may cause changes in your heart rhythm and blood pressure, cause chest pain, or a heart attack. Your doctor will lower your dose gradually over a period of time to help prevent these symptoms. You should not use NEBIVOLOL+S AMLODIPINE if you have a very slow heartbeat, asthma, serious heart condition (sick sinus syndrome), or any heart blockage. It should not be given to children less than 6 years of age. Before taking NEBIVOLOL+S AMLODIPINE, you should tell the doctor if you have any muscle disorder (myasthenia gravis, rhabdomyolysis), breathing problems (COPD, bronchitis, emphysema), low blood sugar level (hypoglycemia), low blood pressure (hypotension), depression, previous heart failure, liver/kidney disease, thyroid hormone disorder, adrenal gland cancer, or problems with circulation (Raynaud’s syndrome). Prolonged intake of NEBIVOLOL+S AMLODIPINE may lead to a lowering of blood pressure. So, you must closely monitor your blood pressure if you ever have had a stroke, heart attack, or currently taking other blood pressure-lowering pills. It is advised to continue taking this drug and not stop taking it suddenly without consulting your doctor.

Drug Interactions

Drug-Drug Interaction: NEBIVOLOL+S AMLODIPINE may interact with other beta-blockers (acebutolol, atenolol, bisoprolol, carteolol, esmolol, metoprolol, nadolol, sotalol), causing a dangerous drop in the heart rate. It also reacts with other anti-hypertensive drugs (aliskiren, amiloride, enalapril, captopril, quinapril, diltiazem). Besides this, NEBIVOLOL+S AMLODIPINE should not be used with other asthma medications (theophylline, aminophylline), potassium-rich supplements, or other painkillers (ibuprofen). If you are using these medicines, tell your doctor before taking NEBIVOLOL+S AMLODIPINE.

Drug-Food Interaction: NEBIVOLOL+S AMLODIPINE is known to interact with grapefruit and protein-enriched foods. Using NEBIVOLOL+S AMLODIPINE together with ayurvedic, homeopathy, Unani, herbal supplements, or any other OTC items may decrease the effects of NEBIVOLOL+S AMLODIPINE. Hence, it is better to maintain at least 2 hours gap between the administration of NEBIVOLOL+S AMLODIPINE and these products.

Drug-Disease Interaction: NEBIVOLOL+S AMLODIPINE should not be given to people with diabetes, thyroid disease, asthma, cardiogenic shock (when the heart fails to pump required blood to the body), heart valve problem (stenosis), low blood pressure (hypotension), coronary heart disease, liver disease or heart failure.

Drug-Drug Interactions Checker List:

  • ALISKIREN
  • AMILORIDE
  • ENALAPRIL
  • CAPTOPRIL
  • QUINAPRIL
  • DILITAZEM
  • THEOPHYLLINE
  • AMINOPHYLLINE
  • IBUPROFEN
  • POTASSIUM
  • ATENOLOL
  • ACEBUTOLOL
  • BISOPROLOL
  • CARTEOLOL
  • ESMOLOL
  • METOPROLOL
  • NADOLOL
  • SOTALOL
  • Safety Advice

    • Safety Warning

      Alcohol

      unsafe

      You are recommended not to consume alcohol along with NEBIVOLOL+S AMLODIPINE to avoid unpleasant side-effects.

    • Safety Warning

      Pregnancy

      unsafe

      NEBIVOLOL+S AMLODIPINE should not be taken until prescribed. NEBIVOLOL+S AMLODIPINE can have some harmful effects on the baby (fetus); your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

    • Safety Warning

      Breast Feeding

      caution

      NEBIVOLOL+S AMLODIPINE is usually not recommended in breastfeeding mothers. Limited human data available suggests that the drug does not do any significant harm to the baby. Consume only if benefits outweigh risks.

    • Safety Warning

      Driving

      unsafe

      It is not recommended to drive after taking NEBIVOLOL+S AMLODIPINE as it may occasionally cause drowsiness or fatigue.

    • Safety Warning

      Liver

      caution

      NEBIVOLOL+S AMLODIPINE to be taken with caution, especially if you have a history of liver diseases/conditions. The dose may have to be adjusted by your doctor.

    • Safety Warning

      Kidney

      caution

      NEBIVOLOL+S AMLODIPINE to be taken with caution, especially if you have a history of kidney diseases/conditions. The dose may have to be adjusted by your doctor.

    • Safety Warning

      Children

      unsafe

      NEBIVOLOL+S AMLODIPINE is not recommended in children below the age of 6 years. The safety and efficacy of NEBIVOLOL+S AMLODIPINE in children have not yet been established.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • Keep your weight under control with BMI (Body Mass Index) 19.5-24.9.
    • Do regular physical activity or exercise for at least 150 minutes per week, or about 30 minutes most days of the week. Doing this can help you to lower your raised blood pressure by about 5 mm of Hg.
    • Opt for a diet rich in whole grains, fruits, veggies, and low-fat dairy products.
    • If you are taking alcohol, then only one serving for women and two servings for men is advisable.
    • Quitting smoking is the best strategy to lower the risk of heart disease.
    • Avoid chronic stress as it can raise your blood pressure. Try to enjoy and spent time with your loved ones to cope with stress and practice mindfulness techniques.
    • Monitor your blood pressure daily and if there is too much fluctuation, then immediately contact your doctor.
    • Try to include heart-healthy omega 3 fatty acids containing food drinks in your daily diet. You can also use low-fat cooking oil like olive oil, soybean oil, canola oil, and coconut oil to lower your elevated blood pressure.

    Special Advise

    • Limit intake of sodium chloride (table salt) in your daily diet to 2300 mg per day or less than 1500 mg is ideal for most adults.

    Patients Concern

    Disease/Condition Glossary

    Hypertension: It is a chronic condition when blood pressure is too high. This condition can lead to hardened arteries (blood vessels), decreasing the blood and oxygen flow to the heart. Blood pressure is the measurement of the force that our heart uses to pump blood to all parts of the body. Raised blood pressure can cause chest pain (angina) and heart attack (when blood supply to the heart is blocked). Additionally, high blood pressure also causes brain damage (stroke) and kidney failure. High blood pressure can be diagnosed with the help of a blood pressure monitor or sphygmomanometer. Systolic pressure is the pressure when the heart pumps blood out. On the other hand, diastolic pressure is when your heart is at the resting stage between heartbeats. If your blood pressure is 140/90 mm of Hg, it means the systolic pressure is 140 mm of Hg, and diastolic pressure is 90 mm of Hg. Ideal blood pressure should be between 90/60 mm of Hg and 120/80 mm of Hg.

    FAQs

    How does NEBIVOLOL+S AMLODIPINE work?

    NEBIVOLOL+S AMLODIPINE is a combination drug containing, S Amlodipine (calcium channel blocker) and Nebivolol (beta-blocker). Both relax the blood vessels, which lowers your blood pressure and reduces your risk of having a stroke, a heart attack, other heart problems, or kidney problems in the future.

    Will I need to stop NEBIVOLOL+S AMLODIPINE before surgery?

    Your doctor may probably tell you to stop taking NEBIVOLOL+S AMLODIPINE as it lowers blood pressure (hypotension) when combined with general anesthesia before surgery. So, please inform your doctor before surgery if you are taking NEBIVOLOL+S AMLODIPINE.

    For how long can I take NEBIVOLOL+S AMLODIPINE?

    Usually, NEBIVOLOL+S AMLODIPINE is prescribed for a long term or life long treatment for hypertension (high blood pressure). You should follow the doctor's advice and take it until your doctor tells you to stop. Suddenly stop taking NEBIVOLOL+S AMLODIPINE may raise your blood pressure and increase your risk of a heart attack.

    Can NEBIVOLOL+S AMLODIPINE cause ankle swelling (edema)?

    Yes, NEBIVOLOL+S AMLODIPINE is known to cause ankle swelling. Please try to keep your feet up when sitting for long hours. If the problem persists still, consult your doctor and do as advised.

    Can taking NEBIVOLOL+S AMLODIPINE cause dry mouth?

    Yes, NEBIVOLOL+S AMLODIPINE can cause dry mouth. Therefore, it is always advised to increase fluid intake while taking NEBIVOLOL+S AMLODIPINE. If you still feel excessively thirsty, please consult your doctor and do as advised for best results of NEBIVOLOL+S AMLODIPINE.

    Available Medicines for

    NEBIVOLOL+S AMLODIPINE